Expression of aquaporin-1, aquaporin-3, and aquaporin-5 correlates with nodal metastasis in colon cancer

Oncology (Switzerland)

Volumn 88, Issue 6, 2015, Pages 369-376

  Kang, Byung Woog ^a   Kim, Jong Gwang ^a   Lee, Soo Jung ^a   Chae, Yee Soo ^a   Jeong, Ji Yun ^a,b   Yoon, Ghil Suk ^a   Park, Soo Yeun ^a   Kim, Hye Jin ^a   Park, Jun Seok ^a   Choi, Gyu Seog ^a  

^a Kyungpook National University School of Medicine   (South Korea)

^b Soonchunhyang University College of Medicine   (South Korea)

Author keywords

Aquaporin; Colorectal cancer; Prognosis

Indexed keywords

AQUAPORIN 1; AQUAPORIN 3; AQUAPORIN 5; CARCINOEMBRYONIC ANTIGEN; FLUOROURACIL; AQP1 PROTEIN, HUMAN; AQP3 PROTEIN, HUMAN; AQP5 PROTEIN, HUMAN;

ADULT; AGED; ARTICLE; CANCER ADJUVANT THERAPY; CANCER PATIENT; CANCER STAGING; CANCER SURGERY; CANCER SURVIVAL; COLON CANCER; DISEASE FREE SURVIVAL; FEMALE; FOLLOW UP; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; LYMPH VESSEL METASTASIS; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PERINEURAL INVASION; PRIORITY JOURNAL; PROTEIN EXPRESSION; TISSUE MICROARRAY; TUMOR INVASION; VERY ELDERLY; COLONIC NEOPLASMS; GENE EXPRESSION REGULATION; GENETIC ASSOCIATION; METABOLISM; MIDDLE AGED; MULTIVARIATE ANALYSIS; PATHOLOGY;

ADULT; AGED; AQUAPORIN 1; AQUAPORIN 3; AQUAPORIN 5; COLONIC NEOPLASMS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC ASSOCIATION STUDIES; HUMANS; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; TISSUE ARRAY ANALYSIS;

EID: 84930155037     PISSN: 00302414     EISSN: 14230232     Source Type: Journal    
DOI: 10.1159/000369073     Document Type: Article

References (25)

1. Ku G, Tan IB, Yau T, Boku N, Laohavinij S, Cheng AL, Kang YK, de Lima Lopes G: Management of colon cancer: resource-stratified guidelines from the Asian Oncology Summit 2012. Lancet Oncol 2012; 13:e470-e481.
2. Ribatti D, Ranieri G, Annese T, Nico B: Aquaporins in cancer. Biochim Biophys Acta 2014; 1840: 1550-1553.
3. Willaert W, Mareel M, Van De Putte D, Van Nieuwenhove Y, Pattyn P, Ceelen W: Lymphatic spread, nodal count and the extent of lymphadenectomy in cancer of the colon. Cancer Treat Rev 2014; 40: 405-413.
4. El Hindy N, Bankfalvi A, Herring A, Adamzik M, Lambertz N, Zhu Y, Siffert W, Sure U, Sandalcioglu IE: Correlation of aquaporin-1 water channel protein expression with tumor angiogenesis in human astrocytoma. Anticancer Res 2013; 33: 609-613.
5. Frede J, Fraser SP, Oskay-Ozcelik G, Hong Y, Ioana Braicu E, Sehouli J, Gabra H, Djamgoz MB: Ovarian cancer: ion channel and aquaporin expression as novel targets of clinical potential. Eur J Cancer 2013; 49: 2331-2344.
6. Liu YL, Matsuzaki T, Nakazawa T, Murata S, Nakamura N, Kondo T, Iwashina M, Mochizuki K, Yamane T, Takata K, Katoh R: Expression of aquaporin 3 (AQP3) in normal and neoplastic lung tissues. Hum Pathol 2007; 38: 171-178.
7. Mobasheri A, Barrett-Jolley R: Aquaporin water channels in the mammary gland: from physiology to pathophysiology and neoplasia. J Mammary Gland Biol Neoplasia 2014; 19: 91-102.
8. Verkman AS: Aquaporins. Curr Biol 2013; 23:R52-R55.
9. Jung HJ, Park JY, Jeon HS, Kwon TH: Aquaporin-5: A marker protein for proliferation and migration of human breast cancer cells. PLoS One 2011; 6:e28492.
10. Lee SJ, Chae YS, Kim JG, Kim WW, Jung JH, Park HY, Jeong JY, Park JY, Jung HJ, Kwon TH: Aqp5 expression predicts survival in patients with early breast cancer. Ann Surg Oncol 2014; 21: 375-383.
11. Yoshida T, Hojo S, Sekine S, Sawada S, Okumura T, Nagata T, Shimada Y, Tsukada K: Expression of aquaporin-1 is a poor prognostic factor for stage II and III colon cancer. Mol Clin Oncol 2013; 1: 953-958.
12. Li A, Lu D, Zhang Y, Li J, Fang Y, Li F, Sun J: Critical role of aquaporin-3 in epidermal growth factor-induced migration of colorectal carcinoma cells and its clinical significance. Oncol Rep 2013; 29: 535-540.
13. Matsuzaki T, Tajika Y, Ablimit A, Aoki T, Hagiwara H, Takata K: Aquaporins in the digestive system. Med Electron Microsc 2004; 37: 71-80.
14. Verkman AS, Anderson MO, Papadopoulos MC: Aquaporins: important but elusive drug targets. Nat Rev Drug Discov 2014; 13: 259-277.
15. Akagi Y, Adachi Y, Kinugasa T, Oka Y, Mizobe T, Shirouzu K: Lymph node evaluation and survival in colorectal cancer: review of population-based, prospective studies. Anticancer Res 2013; 33: 2839-2847.
16. Wang W, Li Q, Yang T, Bai G, Li D, Sun H: Expression of AQP5 and AQP8 in human colorectal carcinoma and their clinical significance. World J Surg Oncol 2012; 10: 242.
17. Aishima S, Kuroda Y, Nishihara Y, Taguchi K, Iguchi T, Taketomi A, Maehara Y, Tsuneyoshi M: Down-regulation of aquaporin-1 in intrahepatic cholangiocarcinoma is related to tumor progression and mucin expression. Hum Pathol 2007; 38: 1819-1825.
18. Kawedia JD, Nieman ML, Boivin GP, Melvin JE, Kikuchi K, Hand AR, Lorenz JN, Menon AG: Interaction between transcellular and paracellular water transport pathways through aquaporin 5 and the tight junction complex. Proc Natl Acad Sci USA 2007; 104: 3621-3626.
19. Martin TA, Jiang WG: Loss of tight junction barrier function and its role in cancer metastasis. Biochim Biophys Acta 2009; 1788: 872-891.
20. Moon C, Soria JC, Jang SJ, Lee J, Obaidul Hoque M, Sibony M, Trink B, Chang YS, Sidransky D, Mao L: Involvement of aquaporins in colorectal carcinogenesis. Oncogene 2003; 22: 6699-6703.
21. Kao SC, Armstrong N, Condon B, Griggs K, McCaughan B, Maltby S, Wilson A, Henderson DW, Klebe S: Aquaporin 1 is an independent prognostic factor in pleural malignant mesothelioma. Cancer 2012; 118: 2952-2961.
22. Sekine S, Shimada Y, Nagata T, Moriyama M, Omura T, Watanabe T, Hori R, Yoshioka I, Okumura T, Sawada S, Fukuoka J, Tsukada K: Prognostic significance of aquaporins in human biliary tract carcinoma. Oncol Rep 2012; 27: 1741-1747.
23. Mobasheri A, Airley R, Hewitt SM, Marples D: Heterogeneous expression of the aquaporin 1 (AQP1) water channel in tumors of the prostate, breast, ovary, colon and lung: A study using high density multiple human tumor tissue microarrays. Int J Oncol 2005; 26: 1149-1158.
24. Pei HP, Liu Z, Huang LS, Zhu H: Significance of aquaporin-1 and aquaporin-3 expression in colorectal carcinoma (in Chinese). Zhonghua Wei Chang Wai Ke Za Zhi 2011; 14: 275-278.
25. Otto W, Rubenwolf PC, Burger M, Fritsche HM, Roßler W, May M, Hartmann A, Hofstadter F, Wieland WF, Denzinger S: Loss of aquaporin 3 protein expression constitutes an independent prognostic factor for progression-free survival: an immunohistochemical study on stage pT1 urothelial bladder cancer. BMC Cancer 2012; 12: 459.