A sphingosine-1 phosphate agonist (FTY720) limits trauma/hemorrhagic shock-induced multiple organ dysfunction syndrome

Shock

Volumn 42, Issue 5, 2014, Pages 448-455

  Bonitz, Joyce ^a   Son, Julie ^a   Chandler, Benjamin ^a   Tomaio, Jacquelyn ^a   Qin, Yong ^a   Prescott, Lauriston ^a   Feketeova, Eleonora ^a   Deitch, Edwin ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

Acute lung injury; lymph; neutrophil activation; red blood cell rigidity

Indexed keywords

EVANS BLUE; FINGOLIMOD; IMMUNOSUPPRESSIVE AGENT; PROPANEDIOL DERIVATIVE; SPHINGOSINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ERYTHROCYTE; HEMORRHAGIC SHOCK; INTESTINE INJURY; LUNG INJURY; LYMPH; LYMPH VESSEL; MALE; MULTIPLE ORGAN FAILURE; NEUTROPHIL; NONHUMAN; PERMEABILITY; RAT; RESPIRATORY BURST; RESUSCITATION; RIGIDITY; ACUTE LUNG INJURY; ANALOGS AND DERIVATIVES; ANIMAL; BLOOD; COMPLICATION; DOSE RESPONSE; DRUG EFFECTS; DRUG SCREENING; ERYTHROCYTE DEFORMABILITY; LEUKOCYTE ACTIVATION; PHYSIOLOGY; PROCEDURES; SHOCK, HEMORRHAGIC; SPRAGUE DAWLEY RAT;

ACUTE LUNG INJURY; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; ERYTHROCYTE DEFORMABILITY; IMMUNOSUPPRESSIVE AGENTS; MALE; MULTIPLE ORGAN FAILURE; NEUTROPHIL ACTIVATION; PROPYLENE GLYCOLS; RATS, SPRAGUE-DAWLEY; RESPIRATORY BURST; SHOCK, HEMORRHAGIC; SPHINGOSINE;

EID: 84930089996     PISSN: 10732322     EISSN: 15400514     Source Type: Journal    
DOI: 10.1097/SHK.0000000000000227     Document Type: Article

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