Local delivery of minocycline-loaded PEG-PLA nanoparticles for the enhanced treatment of periodontitis in dogs

International Journal of Nanomedicine

Volumn 9, Issue 1, 2014, Pages 3963-3970

  Yao, Wenxin ^a   Xu, Peicheng ^a   Pang, Zhiqing ^b,c   Zhao, Jingjing ^b,c   Chai, Zhilan ^b,c   Li, Xiaoxia ^c   Li, Huan ^b,c   Jiang, Menglin ^b,c   Cheng, Hongbo ^b,c   Zhang, Bo ^b,c   Cheng, Nengneng ^c  

^a Shanghai Xuhui District Dental Center ^*  (China)

^b BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^c FUDAN UNIVERSITY   (China)

Author keywords

Local delivery; Minocycline; Nanoparticles; Periodontitis

Indexed keywords

MACROGOL; MINOCYCLINE; NANOPARTICLE; PERIOCLINE; POLYLACTIC ACID; SOLVENT; TETRACYCLINE DERIVATIVE; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; DRUG CARRIER; LACTIC ACID DERIVATIVE; MACROGOL DERIVATIVE; POLY(LACTIC ACID-ETHYLENE GLYCOL);

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIPERIODONTITIS EFFECT; AREA UNDER THE CURVE; ARTICLE; BIODEGRADABILITY; CONTROLLED STUDY; DOG DISEASE; DRUG ACTIVITY; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG ELIMINATION; DRUG HALF LIFE; DRUG PENETRATION; DRUG RELEASE; DRUG RETENTION; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TISSUE LEVEL; DYNAMIC LIGHT SCATTERING; EMULSION; EVAPORATION; GINGIVITIS; IN VITRO STUDY; IN VIVO STUDY; LIGHT SCATTERING; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PARTICLE SIZE; PERIODONTAL POCKET; PERIODONTITIS; STRUCTURE ANALYSIS; SUSTAINED RELEASE PREPARATION; TIME TO MAXIMUM PLASMA CONCENTRATION; TRANSMISSION ELECTRON MICROSCOPY; ZETA POTENTIAL; ANIMAL; CHEMISTRY; DISEASE MODEL; DOG; DRUG EFFECTS; METABOLISM; PERIODONTICS; RANDOMIZATION;

ANIMALS; ANTI-BACTERIAL AGENTS; DISEASE MODELS, ANIMAL; DOGS; DRUG CARRIERS; GINGIVAL CREVICULAR FLUID; LACTATES; MINOCYCLINE; PARTICLE SIZE; PERIODONTAL INDEX; PERIODONTITIS; POLYETHYLENE GLYCOLS; RANDOM ALLOCATION;

EID: 84930079314     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S67521     Document Type: Article

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