Activation of cryptic hop genes from streptomyces peucetius ATCC 27952 involved in hopanoid biosynthesis

Journal of Microbiology and Biotechnology

Volumn 25, Issue 5, 2015, Pages 658-661

  Ghimire, Gopal Prasad ^a   Koirala, Niranjan ^a   Sohng, Jae Kyung ^a  

^a SunMoon University   (South Korea)

Author keywords

Cryptic genes; Genome; Heterologous expression; Hopanoid biosynthesis; S. peucetius

Indexed keywords

HOPANOID; HOPENE; LYASE; POLYPRENYL DIPHOSPHATE SYNTHASE; SQUALENE HOPENE CYCLASE; SQUALENE PHYTOENE SYNTHASE; SYNTHETASE; TRITERPENOID; UNCLASSIFIED DRUG; RECOMBINANT PROTEIN; TRITERPENE;

ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BIOSYNTHESIS; CONTROLLED STUDY; GENE ACTIVATION; GENE CLUSTER; GENETIC TRANSCRIPTION; GENETIC TRANSFORMATION; HETEROLOGOUS EXPRESSION; HOP GENE; HOPAB GENE; HOPD GENE; HOPE GENE; MASS FRAGMENTOGRAPHY; MOLECULAR CLONING; NONHUMAN; POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY; STREPTOMYCES; STREPTOMYCES PEUCETIUS; STREPTOMYCES VENEZUELAE; GENETICS; METABOLISM; MULTIGENE FAMILY;

STREPTOMYCES PEUCETIUS ATCC 27952; STREPTOMYCES VENEZUELAE;

CLONING, MOLECULAR; GENES, BACTERIAL; MULTIGENE FAMILY; RECOMBINANT PROTEINS; STREPTOMYCES; TRITERPENES;

EID: 84930000615     PISSN: 10177825     EISSN: 17388872     Source Type: Journal    
DOI: 10.4014/jmb.1408.08058     Document Type: Article

References (25)

1. Anding C, Rohmer M, Qurisson G. 1976. Nonspecific biosynthesis of hopane triterpenes in a cell-free system from Acetobacter rancens. J. Am. Chem. Soc. 98: 1274-1275.
2. Bisseret P, Wolff G, Albrecht AM, Tanaka T, Nakatani Y, Ourisson G. 1983. A direct study of the cohesion of lecithin bilayers: the effect of hopanoids and α,ω- dihydroxycarotenoids. Biochem. Biophys. Res. Commun. 110: 320-324.
3. Bligh EG, Dyer WJ. 1959. A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 37: 911-917.
4. Corey EJ, Russey WE, Ortiz de Montellano PR. 1966. 2,3- Oxidosqualene, an intermediate in the biological synthesis of sterols from squalene. J. Am. Chem. Soc. 88: 4750-4751.
5. Ghimire GP, Oh TJ, Liou K, Sohng JK. 2008. Identification of a cryptic type III polyketide synthase (1,3,6,8-tetrahydroxynaphthalene synthase) from Streptomyces peucetius ATCC 27952. Mol. Cells 26: 362-367.
6. Ghimire GP, Oh TJ, Lee HC, Kim BG, Sohng JK. 2008. Cloning and functional characterization of germacradienol synthase (spterp13) from Streptomyces peucetius ATCC 27952. J. Microbiol. Biotechnol. 18: 1216-1220.
7. Ghimire GP, Oh TJ, Lee HC, Sohng JK. 2009. Squalene-hopene cyclase (Spterp25) from Streptomyces peucetius: sequence analysis, expression and functional characterization. Biotechnol. Lett. 31: 565-569.
8. Ghimire GP, Lee HC, Sohng JK. 2009. Improved squalene production via modulation of the methylerythritol 4-phosphate pathway and heterologous expression of genes from Streptomyces peucetius ATCC 27952 in Escherichia coli. Appl. Environ. Microbiol. 75: 7291-7293.
9. Goldstein JL, Brown MS. 1990. Regulation of the mevalonate pathway. Nature 343: 425-430.
10. Jones GH, Hopwood DA. 1984. Activation of phenoxazinone synthase expression in Streptomyces lividans by cloned DNA sequences from Streptomyces antibioticus. J. Biol. Chem. 259: 14158-14164.
11. Kannenberg EL, Perzl M, Muller P, Hartner T, Poralla K. 1996. Hopanoid lipids in Bradyrhizobium a nd other plant-associa ted bacteria and cloning of the Bradyrhizobium japonicum squalenehopene cyclase. Plant Soil 186: 107-112.
12. Kannenberg EL, Poralla K. 1999. Hopanoid biosynthesis and function in bacteria. Naturwissenschaften 86: 168-176.
13. Kieser T, Bibb MJ, Buttner MJ, Chater KF, Hopwood DA. 2000. Practical Streptomyces Genetics. The John Innes Foundation, Norwich, England.
14. Meyer O, Grosdemanage-Billard C, Tritsch D, Rohmer M. 2003. Isoprenoid biosynthesis via the MEP pathway. Synthesis of (3R,4S)-3,4-dihydroxy-5-oxohexylphosphonic acid, an isosteric analogue of 1-deoxy-D-xylulose 5-phosphate, the substrate of the 1-deoxy-D-xylulose 5-phosphate reductoisomerase. Org. Biomol. Chem. 1: 4367-4372.
15. Palmu K, Ishida K, Mantsala P, Hertweck C, Mesta-Ketele M. 2007. Artificial reconstruction of two cryptic angucycline antibiotic biosynthetic pathways. Chembiochem 8: 1577-1584.
16. Pa rker LL, B etts PW, Hall BG. 1988. Activa tion o f a c ryptic gene by excision of a DNA fragment. J. Bacteriol. 170: 218-222.
17. Poralla K, Kannenberg E, Blume A. 1980. A glycolipid containing hopane isolated from Bacillus acidocaldarius has a cholesterol like function in membranes. FEBS Lett. 113: 107-110.
18. Poralla K, Hartner T, Kannenberg E. 1984. Effect of temperature and pH on the hopanoid content of Bacillus acidocaldarius. FEMS Microbiol. Lett. 23: 253-256.
19. Poralla K, Muth G, Harter T. 2000. Hopanoids are formed during transition from substrate to aerial hyphae in Streptomyces coelicolor A3 (2). FEMS Microbiol. Lett. 189: 93-95.
20. Qurisson G, Albrecht P, Rohmer M. 1979. The hopanoids: paleochemistry and biochemistry of a group of natural products. Pure Appl. Chem. 51: 709-729.
21. Roberts SC. 2007. Production and engineering of terpenoids in plant cell culture. Nat. Chem. Biol. 3: 387-395.
22. Rohmer M, Bouvier-Nave P, Ourisson G. 1984. Distribution of hopaniods in prokaryotes. J. Gen. Microbiol. 130: 1137-1150.
23. Sahm H, Rhomer M, Bringer-Meyer S, Sprenger GA, Welle R. 1993. Biochemistry and physiology of hopanoids in bacteria. Adv. Microb. Physiol. 35: 247-273.
24. Van Tamelen EE, Willett JD, Clayton RB, Lord KE. 1966. Enzymatic conversion of squalene 2,3-oxide to lanosterol and cholesterol. J. Am. Chem. Soc. 88: 4752-4754.
25. Withers ST, Keasling JD. 2007. Biosynthesis and engineering of isoprenoid small molecules. Appl. Microbiol. Biotechnol. 73: 980-990.