Transcriptional repression of ER through hMAPK dependent histone deacetylation by class I HDACs

Breast Cancer Research and Treatment

Volumn 147, Issue 2, 2014, Pages 249-263

  Plotkin, Amy ^a   Volmar, Claude Henry ^a   Wahlestedt, Claes ^a   Ayad, Nagi ^a   El Ashry, Dorraya ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

Breast cancer; Estrogen receptor; HDAC; Histone deacetylase inhibitor; Hormonal status; MAPK; Transcriptional repression

Indexed keywords

ESTROGEN RECEPTOR; HDAC1 PROTEIN, HUMAN; HISTONE DEACETYLASE; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE INHIBITOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE;

ACETYLATION; BIOSYNTHESIS; BREAST NEOPLASMS; DNA METHYLATION; DRUG EFFECTS; FEMALE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; HUMAN; MCF 7 CELL LINE; METABOLISM; PROMOTER REGION; TUMOR CELL LINE;

ACETYLATION; BREAST NEOPLASMS; CELL LINE, TUMOR; DNA METHYLATION; FEMALE; GENE EXPRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; HUMANS; MCF-7 CELLS; MITOGEN-ACTIVATED PROTEIN KINASES; PROMOTER REGIONS, GENETIC; RECEPTORS, ESTROGEN; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

EID: 84929989448     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-014-3093-5     Document Type: Article

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