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Volumn 79, Issue 1, 2015, Pages 50-56

Connexin 43 deficiency accelerates skin wound healing and extracellular matrix remodeling in mice

Author keywords

Connexin 43; Gap junction; Skin repair; Wound healing

Indexed keywords

COLLAGEN TYPE 1; COLLAGEN TYPE 3; CONNEXIN 43; GELATINASE A; MESSENGER RNA; TRANSFORMING GROWTH FACTOR BETA1; COLLAGEN;

EID: 84929955715     PISSN: 09231811     EISSN: 1873569X     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2015.03.019     Document Type: Article
Times cited : (38)

References (35)
  • 1
    • 84861583607 scopus 로고    scopus 로고
    • Connexins in wound healing; perspectives in diabetic patients
    • Becker D.L., Thrasivoulou C., Phillips A.R. Connexins in wound healing; perspectives in diabetic patients. Biochim Biophys Acta 2012, 1818:2068-2075.
    • (2012) Biochim Biophys Acta , vol.1818 , pp. 2068-2075
    • Becker, D.L.1    Thrasivoulou, C.2    Phillips, A.R.3
  • 3
    • 84878529977 scopus 로고    scopus 로고
    • Gap junction remodeling in skin repair following wounding and disease
    • Churko J.M., Laird D.W. Gap junction remodeling in skin repair following wounding and disease. Physiology 2013, 28:190-198.
    • (2013) Physiology , vol.28 , pp. 190-198
    • Churko, J.M.1    Laird, D.W.2
  • 4
    • 84898904766 scopus 로고    scopus 로고
    • Connexins: sensors of epidermal integrity that are therapeutic targets
    • Martin P.E., Easton J.A., Hodgins M.B., Wright C.S. Connexins: sensors of epidermal integrity that are therapeutic targets. FEBS Lett 2014, 588:1304-1314.
    • (2014) FEBS Lett , vol.588 , pp. 1304-1314
    • Martin, P.E.1    Easton, J.A.2    Hodgins, M.B.3    Wright, C.S.4
  • 5
    • 21344468839 scopus 로고    scopus 로고
    • Limiting burn extension by transient inhibition of connexin 43 expression at the site of injury
    • Coutinho P., Qiu C., Frank S., Wang C.M., Brown T., Green C.R., et al. Limiting burn extension by transient inhibition of connexin 43 expression at the site of injury. Br J Plast Surg 2005, 58:658-667.
    • (2005) Br J Plast Surg , vol.58 , pp. 658-667
    • Coutinho, P.1    Qiu, C.2    Frank, S.3    Wang, C.M.4    Brown, T.5    Green, C.R.6
  • 6
    • 78649739295 scopus 로고    scopus 로고
    • Connexin 43 mimetic peptide Gap27 reveals potential differences in the role of Cx43 in wound repair between diabetic and non-diabetic cells
    • Pollok S., Pfeiffer A.C., Lobmann R., Wright C.S., Moll I., Martin P.E., et al. Connexin 43 mimetic peptide Gap27 reveals potential differences in the role of Cx43 in wound repair between diabetic and non-diabetic cells. J Cell Mol Med 2011, 15:861-873.
    • (2011) J Cell Mol Med , vol.15 , pp. 861-873
    • Pollok, S.1    Pfeiffer, A.C.2    Lobmann, R.3    Wright, C.S.4    Moll, I.5    Martin, P.E.6
  • 7
    • 2442417362 scopus 로고    scopus 로고
    • Connexins 26, 30, and 43: differences among spontaneous, chronic, and accelerated human wound healing
    • Brandner J.M., Houdek P., Hüsing B., Kaiser C., Moll I. Connexins 26, 30, and 43: differences among spontaneous, chronic, and accelerated human wound healing. J Investig Dermatol 2004, 122:1310-1320.
    • (2004) J Investig Dermatol , vol.122 , pp. 1310-1320
    • Brandner, J.M.1    Houdek, P.2    Hüsing, B.3    Kaiser, C.4    Moll, I.5
  • 8
    • 0041884855 scopus 로고    scopus 로고
    • Altered connexin expression and wound healing in the epidermis of connexin-deficient mice
    • Kretz M., Euwens C., Hombach S., Eckardt D., Teubner B., Traub O., et al. Altered connexin expression and wound healing in the epidermis of connexin-deficient mice. J Cell Sci 2003, 116:3443-3452.
    • (2003) J Cell Sci , vol.116 , pp. 3443-3452
    • Kretz, M.1    Euwens, C.2    Hombach, S.3    Eckardt, D.4    Teubner, B.5    Traub, O.6
  • 9
    • 0141615015 scopus 로고    scopus 로고
    • Targeting connexin 43 expression accelerates the rate of wound repair
    • Qiu C., Coutinho P., Frank S., Franke S., Law L.Y., Martin P., et al. Targeting connexin 43 expression accelerates the rate of wound repair. Curr Biol 2003, 13:1697-1703.
    • (2003) Curr Biol , vol.13 , pp. 1697-1703
    • Qiu, C.1    Coutinho, P.2    Frank, S.3    Franke, S.4    Law, L.Y.5    Martin, P.6
  • 10
    • 33846142148 scopus 로고    scopus 로고
    • Acute downregulation of connexin 43 at wound sites leads to a reduced inflammatory response, enhanced keratinocyte proliferation and wound fibroblast migration
    • Mori R., Power K.T., Wang C.M., Martin P., Becker D.L. Acute downregulation of connexin 43 at wound sites leads to a reduced inflammatory response, enhanced keratinocyte proliferation and wound fibroblast migration. J Cell Sci 2006, 119:5193-5203.
    • (2006) J Cell Sci , vol.119 , pp. 5193-5203
    • Mori, R.1    Power, K.T.2    Wang, C.M.3    Martin, P.4    Becker, D.L.5
  • 11
    • 33847241891 scopus 로고    scopus 로고
    • Variations in gap junctional intercellular communication and connexin expression in fibroblasts derived from keloid and hypertrophic scars
    • Lu F., Gao J., Ogawa R., Hyakusoku H. Variations in gap junctional intercellular communication and connexin expression in fibroblasts derived from keloid and hypertrophic scars. Plast Reconstr Surg 2007, 119:844-851.
    • (2007) Plast Reconstr Surg , vol.119 , pp. 844-851
    • Lu, F.1    Gao, J.2    Ogawa, R.3    Hyakusoku, H.4
  • 12
    • 35748935253 scopus 로고    scopus 로고
    • Abnormal connexin expression underlies delayed wound healing in diabetic skin
    • Wang C.M., Lincoln J., Cook J.E., Becker D.L. Abnormal connexin expression underlies delayed wound healing in diabetic skin. Diabetes 2007, 56:2809-2817.
    • (2007) Diabetes , vol.56 , pp. 2809-2817
    • Wang, C.M.1    Lincoln, J.2    Cook, J.E.3    Becker, D.L.4
  • 14
    • 79954453232 scopus 로고    scopus 로고
    • Morphological and molecular pathology of CCL4-induced hepatic fibrosis in connexin 43-deficient mice
    • Cogliati B., Da Silva T.C., Aloia T.P., Chaible L.M., Real-Lima M.A., Sanches D.S., et al. Morphological and molecular pathology of CCL4-induced hepatic fibrosis in connexin 43-deficient mice. Microsc Res Tech 2011, 74:421-429.
    • (2011) Microsc Res Tech , vol.74 , pp. 421-429
    • Cogliati, B.1    Da Silva, T.C.2    Aloia, T.P.3    Chaible, L.M.4    Real-Lima, M.A.5    Sanches, D.S.6
  • 15
    • 24944485546 scopus 로고    scopus 로고
    • Animal models for adult dermal wound healing
    • Birch M., Tomlinson A., Ferguson M.W. Animal models for adult dermal wound healing. Methods Mol Med 2005, 117:223-235.
    • (2005) Methods Mol Med , vol.117 , pp. 223-235
    • Birch, M.1    Tomlinson, A.2    Ferguson, M.W.3
  • 16
    • 0014310218 scopus 로고
    • Studies on the biology of collagen during wound healing. Rate of collagen synthesis and deposition in cutaneous wounds in the rat
    • Madden J.W., Peacock E.E. Studies on the biology of collagen during wound healing. Rate of collagen synthesis and deposition in cutaneous wounds in the rat. Surgery 1968, 64:288-294.
    • (1968) Surgery , vol.64 , pp. 288-294
    • Madden, J.W.1    Peacock, E.E.2
  • 17
    • 64149097786 scopus 로고    scopus 로고
    • The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments
    • Bustin S.A., Benes V., Garson J.A., Hellemans J., Huggett J., Kubista M., et al. The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. Clin Chem 2009, 55:611-622.
    • (2009) Clin Chem , vol.55 , pp. 611-622
    • Bustin, S.A.1    Benes, V.2    Garson, J.A.3    Hellemans, J.4    Huggett, J.5    Kubista, M.6
  • 18
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
    • Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 2001, 25:402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 19
    • 0014089460 scopus 로고
    • Intercellular communication and tissue growth. I. Cancerous growth
    • Loewenstein W.R., Kanno Y. Intercellular communication and tissue growth. I. Cancerous growth. J Cell Biol 1967, 33:225-234.
    • (1967) J Cell Biol , vol.33 , pp. 225-234
    • Loewenstein, W.R.1    Kanno, Y.2
  • 20
    • 0014097086 scopus 로고
    • Hexagonal array of subunits in intercellular junctions of the mouse heart and liver
    • Revel J.P., Karnovsky M.J. Hexagonal array of subunits in intercellular junctions of the mouse heart and liver. J Cell Biol 1967, 33:C7-C12.
    • (1967) J Cell Biol , vol.33 , pp. C7-C12
    • Revel, J.P.1    Karnovsky, M.J.2
  • 21
    • 0016366332 scopus 로고
    • Bulk isolation of mouse hepatocyte gap junctions. Characterization of the principal protein, connexin
    • Goodenough D.A. Bulk isolation of mouse hepatocyte gap junctions. Characterization of the principal protein, connexin. J Cell Biol 1974, 61:557-563.
    • (1974) J Cell Biol , vol.61 , pp. 557-563
    • Goodenough, D.A.1
  • 22
    • 0029950947 scopus 로고    scopus 로고
    • Role of connexin genes in growth control
    • Yamasaki H., Naus C.C. Role of connexin genes in growth control. Carcinogenesis 1996, 17:1199-1213.
    • (1996) Carcinogenesis , vol.17 , pp. 1199-1213
    • Yamasaki, H.1    Naus, C.C.2
  • 24
    • 0030250227 scopus 로고    scopus 로고
    • Role of disrupted gap junctional intercellular communication in detection and characterization of carcinogens
    • Yamasaki H. Role of disrupted gap junctional intercellular communication in detection and characterization of carcinogens. Mutat Res 1996, 365:91-105.
    • (1996) Mutat Res , vol.365 , pp. 91-105
    • Yamasaki, H.1
  • 25
    • 0000299698 scopus 로고    scopus 로고
    • Cell-cell communication in carcinogenesis
    • d208ÿd236
    • Trosko J.E., Ruch R.J. Cell-cell communication in carcinogenesis. Front Biosci 1998, 3:d208ÿd236.
    • (1998) Front Biosci , vol.3
    • Trosko, J.E.1    Ruch, R.J.2
  • 26
    • 0036890347 scopus 로고    scopus 로고
    • Gap junctions as targets for cancer chemoprevention and chemotherapy
    • Trosko J.E., Ruch R.J. Gap junctions as targets for cancer chemoprevention and chemotherapy. Curr Drug Targets 2002, 3:465-482.
    • (2002) Curr Drug Targets , vol.3 , pp. 465-482
    • Trosko, J.E.1    Ruch, R.J.2
  • 29
    • 34250807258 scopus 로고    scopus 로고
    • Aberrant hemichannel properties of Cx26 mutations causing skin disease and deafness
    • Gerido D.A., DeRosa A.M., Richard G., White T.W. Aberrant hemichannel properties of Cx26 mutations causing skin disease and deafness. Am J Physiol Cell Physiol 2004, 293:C337-C345.
    • (2004) Am J Physiol Cell Physiol , vol.293 , pp. C337-C345
    • Gerido, D.A.1    DeRosa, A.M.2    Richard, G.3    White, T.W.4
  • 30
    • 84055176143 scopus 로고    scopus 로고
    • The Cx26-G45E mutation displays increased hemichannel activity in a mouse model of the lethal form of keratitis-ichthyosis-deafness syndrome
    • Mese G., Sellitto C., Li L., Wang H.Z., Valiunas V., Richard G., et al. The Cx26-G45E mutation displays increased hemichannel activity in a mouse model of the lethal form of keratitis-ichthyosis-deafness syndrome. Mol Biol Cell 2011, 22:4776-4786.
    • (2011) Mol Biol Cell , vol.22 , pp. 4776-4786
    • Mese, G.1    Sellitto, C.2    Li, L.3    Wang, H.Z.4    Valiunas, V.5    Richard, G.6
  • 31
    • 84879171256 scopus 로고    scopus 로고
    • The human Cx26-D50A and Cx26-A88V mutations causing keratitis-ichthyosis-deafness syndrome display increased hemichannel activity
    • Mhaske P.V., Levit N.A., Li L., Wang H.Z., Lee J.R., Shuja Z., et al. The human Cx26-D50A and Cx26-A88V mutations causing keratitis-ichthyosis-deafness syndrome display increased hemichannel activity. Am J Physiol Cell Physiol 2013, 304:C1150-C1158.
    • (2013) Am J Physiol Cell Physiol , vol.304 , pp. C1150-C1158
    • Mhaske, P.V.1    Levit, N.A.2    Li, L.3    Wang, H.Z.4    Lee, J.R.5    Shuja, Z.6
  • 32
    • 0032932259 scopus 로고    scopus 로고
    • Cell-to-cell communication and expression of gap junctional proteins in human diabetic and nondiabetic skin fibroblasts: effects of basic fibroblast growth factor
    • Abdullah K.M., Luthra G., Bilski J.J., Abdullah S.A., Reynolds L.P., Redmer D.A., et al. Cell-to-cell communication and expression of gap junctional proteins in human diabetic and nondiabetic skin fibroblasts: effects of basic fibroblast growth factor. Endocrine 1999, 10:35-41.
    • (1999) Endocrine , vol.10 , pp. 35-41
    • Abdullah, K.M.1    Luthra, G.2    Bilski, J.J.3    Abdullah, S.A.4    Reynolds, L.P.5    Redmer, D.A.6
  • 34
    • 62449100273 scopus 로고    scopus 로고
    • Connexin mimetic peptides improve cell migration rates of human epidermal keratinocytes and dermal fibroblasts in vitro
    • Wright C.S., van Steensel M.A., Hodgins M.B., Martin P.E. Connexin mimetic peptides improve cell migration rates of human epidermal keratinocytes and dermal fibroblasts in vitro. Wound Repair Regen 2009, 17:240-249.
    • (2009) Wound Repair Regen , vol.17 , pp. 240-249
    • Wright, C.S.1    van Steensel, M.A.2    Hodgins, M.B.3    Martin, P.E.4
  • 35
    • 80054951128 scopus 로고    scopus 로고
    • The connexin mimetic peptide Gap27 increases human dermal fibroblast migration in hyperglycemic and hyperinsulinemic conditions in vitro
    • Wright C.S., Pollok S., Flint D.J., Brandner J.M., Martin P.E. The connexin mimetic peptide Gap27 increases human dermal fibroblast migration in hyperglycemic and hyperinsulinemic conditions in vitro. J Cell Physiol 2012, 227:77-87.
    • (2012) J Cell Physiol , vol.227 , pp. 77-87
    • Wright, C.S.1    Pollok, S.2    Flint, D.J.3    Brandner, J.M.4    Martin, P.E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.