Association between circulating irisin and homocysteine in patients with nonalcoholic fatty liver disease

Endocrine

Volumn 49, Issue 2, 2015, Pages 560-562

  Polyzos, Stergios A ^a,b   Kountouras, Jannis ^c   Anastasilakis, Athanasios D ^c   Margouta, Anastasia ^d   Mantzoros, Christos S ^b  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^b HARVARD MEDICAL SCHOOL   (United States)

^c 424 General Army Hospital   (Greece)

^d UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; GAMMA GLUTAMYLTRANSFERASE; HOMOCYSTEINE; INSULIN; IRISIN; TRIACYLGLYCEROL; FIBRONECTIN; FNDC5 PROTEIN, HUMAN;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; HUMAN; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; LETTER; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; NON INSULIN DEPENDENT DIABETES MELLITUS; NONALCOHOLIC FATTY LIVER; OBESITY; PRIORITY JOURNAL; TRIACYLGLYCEROL BLOOD LEVEL; BLOOD;

FEMALE; FIBRONECTINS; HOMOCYSTEINE; HUMANS; MALE; MIDDLE AGED; NON-ALCOHOLIC FATTY LIVER DISEASE;

EID: 84929947111     PISSN: 1355008X     EISSN: 15590100     Source Type: Journal    
DOI: 10.1007/s12020-014-0473-x     Document Type: Letter

References (15)

1. S.A. Polyzos, J. Kountouras, C. Zavos, Nonalcoholic fatty liver disease: the pathogenetic roles of insulin resistance and adipocytokines. Curr. Mol. Med. 9, 299–314 (2009)
2. S.A. Polyzos, J. Kountouras, C. Zavos, G. Deretzi, Nonalcoholic fatty liver disease: multimodal treatment options for a pathogenetically multiple-hit disease. J. Clin. Gastroenterol. 46, 272–284 (2012)
3. M.J. Armstrong, L.A. Adams, A. Canbay, W.K. Syn, Extrahepatic complications of nonalcoholic fatty liver disease. Hepatology 59, 1174–1197 (2014)
4. S.A. Polyzos, J. Kountouras, K. Shields, C.S. Mantzoros, Irisin: a renaissance in metabolism? Metabolism 62, 1037–1044 (2013)
5. K.N. Aronis, M. Moreno, S.A. Polyzos, J.M. Moreno-Navarrete, W. Ricart, E. Delgado, J. de la Hera, A. Sahin-Efe, J.P. Chamberland, R. Berman, A. Spiro Iii, P. Vokonas, P. Vokonas, J.M. Fernandez-Real, C.S. Mantzoros, Circulating irisin levels and coronary heart disease: association with future acute coronary syndrome and major adverse cardiovascular events. Int. J. Obes. (2013). doi:10.1038/ijo.2014.101
6. H.S. Moon, C.S. Mantzoros, Regulation of cell proliferation and malignant potential by irisin in endometrial, colon, thyroid and esophageal cancer cell lines. Metabolism 63, 188–193 (2014)
7. D.S. Wald, M. Law, J.K. Morris, Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis. B.M.J. 325, 1202 (2002)
8. K. Yu, J. Zhang, J. Zhang, C. Dou, S. Gu, Y. Xie, Y. Mao, C. Ji, Methionine synthase A2756G polymorphism and cancer risk: a meta-analysis. Eur. J. Hum. Genet. 18, 370–378 (2010)
9. F. Sanchis-Gomar, R. Alis, H. Pareja-Galeano, E. Sola, V.M. Victor, M. Rocha, A. Hernandez-Mijares, M. Romagnoli, Circulating irisin levels are not correlated with BMI, age, and other biological parameters in obese and diabetic patients. Endocrine 46, 674–677 (2014)
10. R. Alis, F. Sanchis-Gomar, H. Pareja-Galeano, A. Hernandez-Mijares, M. Romagnoli, V.M. Victor, M. Rocha, Association between irisin and homocysteine in euglycemic and diabetic subjects. Clin. Biochem. (2014). doi:10.1016/j.clinbiochem.2014.08.017
11. S.A. Polyzos, J. Kountouras, A.D. Anastasilakis, E.V. Geladari, C.S. Mantzoros, Irisin in patients with nonalcoholic fatty liver disease. Metabolism 63, 207–217 (2014)
12. S.A. Polyzos, J. Kountouras, K. Patsiaoura, E. Katsiki, E. Zafeiriadou, G. Deretzi, C. Zavos, E. Gavalas, P. Katsinelos, V. Mane, A. Slavakis, Serum homocysteine levels in patients with nonalcoholic fatty liver disease. Ann. Hepatol. 11, 68–76 (2012)
13. D.E. Kleiner, E.M. Brunt, M. Van Natta, C. Behling, M.J. Contos, O.W. Cummings, L.D. Ferrell, Y.C. Liu, M.S. Torbenson, A. Unalp-Arida, M. Yeh, A.J. McCullough, A.J. Sanyal, Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology 41, 1313–1321 (2005)
14. D. Kraus, Q. Yang, D. Kong, A.S. Banks, L. Zhang, J.T. Rodgers, E. Pirinen, T.C. Pulinilkunnil, F. Gong, Y.C. Wang, Y. Cen, A.A. Sauve, J.M. Asara, O.D. Peroni, B.P. Monia, S. Bhanot, L. Alhonen, P. Puigserver, B.B. Kahn, Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity. Nature 508, 258–262 (2014)
15. C. Canto, J. Auwerx, NAD + as a signaling molecule modulating metabolism. Cold Spring Harb. Symp. Quant. Biol. 76, 291–298 (2011)