Quadriceps muscle weakness and atrophy are associated with a differential epigenetic profile in advanced COPD

Clinical Science

Volumn 128, Issue 12, 2015, Pages 905-921

  Puig Vilanova, Ester ^a,b   Martínez Llorens, Juana ^a,b   Ausin, Pilar ^a,b   Roca, Josep ^b,c   Gea, Joaquim ^a,b   Barreiro, Esther ^a,b  

^a UNIVERSITAT POMPEU FABRA   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Atrophy; Chronic obstructive pulmonary disease (COPD); Comorbidities; Epigenetic regulation; Limb muscle weakness; Muscle growth signalling

Indexed keywords

FOLLISTATIN; HISTONE; HISTONE ACETYLTRANSFERASE; HISTONE DEACETYLASE; HISTONE DEACETYLASE 3; HISTONE DEACETYLASE 4; HISTONE H3; HISTONE H4; MICRORNA; MICRORNA 1; MICRORNA 206; MICRORNA 27A; MYOSTATIN; PROTEIN KINASE B; SERUM RESPONSE FACTOR; SIRTUIN 1; SOMATOMEDIN C; SUMO PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; BIOLOGICAL MARKER;

AGED; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; EPIGENETICS; GENE EXPRESSION PROFILING; GENETIC ASSOCIATION; HISTONE ACETYLATION; HUMAN; HUMAN TISSUE; MALE; MUSCLE ATROPHY; MUSCLE CELL; MUSCLE DEVELOPMENT; MUSCLE GROWTH; MUSCLE WEAKNESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUADRICEPS FEMORIS MUSCLE; SEDENTARY LIFESTYLE; SIGNAL TRANSDUCTION; VASTUS LATERALIS MUSCLE; ANTHROPOMETRY; CASE CONTROL STUDY; COMPLICATION; GENETIC EPIGENESIS; GENETICS; METABOLISM; MUSCULAR ATROPHY; PATHOLOGY; PATHOPHYSIOLOGY; PROCEDURES;

ANTHROPOMETRY; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; EPIGENESIS, GENETIC; HUMANS; MALE; MICRORNAS; MUSCLE WEAKNESS; MUSCULAR ATROPHY; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; QUADRICEPS MUSCLE;

EID: 84929941350     PISSN: 01435221     EISSN: 14708736     Source Type: Journal    
DOI: 10.1042/CS20140428     Document Type: Article

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