Neuromotor control in chronic obstructive pulmonary disease

Journal of Applied Physiology

Volumn 114, Issue 9, 2013, Pages 1246-1252

  Mantilla, Carlos B ^a   Sieck, Gary C ^a  

^a MAYO CLINIC   (United States)

Author keywords

Diaphragm muscle; Fiber type; Motor control; Motor unit; Respiratory muscles

Indexed keywords

BREATHING MUSCLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; DIAPHRAGM MUSCLE; ENDURANCE; FIBER TYPE; HUMAN; INNERVATION; MOTONEURON; MOTOR CONTROL; MOTOR UNIT; MUSCLE FATIGUE; NEUROPHYSIOLOGICAL RECRUITMENT; PATHOPHYSIOLOGY; PHYSIOLOGY; REVIEW; SKELETAL MUSCLE;

DIAPHRAGM MUSCLE; FIBER TYPE; MOTOR CONTROL; MOTOR UNIT; RESPIRATORY MUSCLES;

HUMANS; MOTOR NEURONS; MUSCLE FATIGUE; MUSCLE FIBERS, SKELETAL; MUSCLE, SKELETAL; PHYSICAL ENDURANCE; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RECRUITMENT, NEUROPHYSIOLOGICAL; RESPIRATORY MUSCLES;

EID: 84878567678     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.01212.2012     Document Type: Review

References (69)

1. Barreiro E, Ferrer D, Sanchez F, Minguella J, Marin-Corral J, Martinez-Llorens J, Lloreta J, Gea J. Inflammatory cells and apoptosis in respiratory and limb muscles of patients with COPD. J Appl Physiol 111:808-817, 2011.
2. Beck J, Gottfried SB, Navalesi P, Skrobik Y, Comtois N, Rossini M, Sinderby C. Electrical activity of the diaphragm during pressure support ventilation in acute respiratory failure. Am J Respir Crit Care Med 164:419-424, 2001. (Pubitemid 32778209)
3. Beck J, Sinderby C, Lindstrom L, Grassino A. Crural diaphragm activation during dynamic contractions at various inspiratory flow rates. J Appl Physiol 85:451-458, 1998. (Pubitemid 28365810)
4. Beck J, Sinderby C, Lindstrom L, Grassino A. Influence of bipolar esophageal electrode positioning on measurements of human crural diaphragm electromyogram. J Appl Physiol 81:1434-1449, 1996. (Pubitemid 26309159)
5. Burke RE. Motor units: anatomy, physiology and functional organization. In: Handbook of Physiology The Nervous System Motor Control. Bethesda, MD: Am. Physiol. Soc., 1981, p. 345-422.
6. Burke RE, Levine DN, Tsairis P, Zajac FE 3rd. Physiological types and histochemical profiles in motor units of the cat gastrocnemius. J Physiol 234:723-748, 1973.
7. Butler JE, McKenzie DK, Gandevia SC. Discharge properties and recruitment of human diaphragmatic motor units during voluntary inspiratory tasks. J Physiol 518:907-920, 1999. (Pubitemid 29387257)
8. Caron MA, Debigare R, Dekhuijzen PN, Maltais F. Comparative assessment of the quadriceps and the diaphragm in patients with COPD. J Appl Physiol 107:952-961, 2009.
9. Clamann HP. Motor unit recruitment and the gradation of muscle force. Phys Ther 73:830-843, 1993. (Pubitemid 23352667)
10. Clanton TL, Levine S. Respiratory muscle fiber remodeling in chronic hyperinflation: dysfunction or adaptation? J Appl Physiol 107:324-335, 2009.
11. De Troyer A, Leeper JB, McKenzie DK, Gandevia SC. Neural drive to the diaphragm in patients with severe COPD. Am J Respir Crit Care Med 155:1335-1340, 1997. (Pubitemid 27172780)
12. Decramer M, Stas KJ. Corticosteroid-induced myopathy involving respiratory muscles in patients with chronic obstructive pulmonary disease or asthma. Am Rev Respir Dis 146:800-802, 1992.
13. Dick TE, Kong FJ, Berger AJ. Correlation of recruitment order with axonal conduction velocity for supraspinally driven diaphragmatic motor units. J Neurophysiol 57:245-259, 1987. (Pubitemid 17036265)
14. Enad JG, Fournier M, Sieck GC. Oxidative capacity and capillary density of diaphragm motor units. J Appl Physiol 67:620-627, 1989. (Pubitemid 19218657)
15. Fournier M, Sieck GC. Mechanical properties of muscle units in the cat diaphragm. J Neurophysiol 59:1055-1066, 1988.
16. Gasser HS, Grundfest H. Axon diameters in relation to the spike dimensions and the conduction velocity in mammalian A fibers. Am J Physiol 127:393-414, 1939.
17. Geiger PC, Cody MJ, Han YS, Hunter LW, Zhan WZ, Sieck GC. Effects of hypothyroidism on maximum specific force in rat diaphragm muscle fibers. J Appl Physiol 92:1506-1514, 2002. (Pubitemid 34670906)
18. Geiger PC, Cody MJ, Macken RL, Bayrd ME, Sieck GC. Mechanisms underlying increased force generation by rat diaphragm muscle fibers during development. J Appl Physiol 90:380-388, 2001. (Pubitemid 32038541)
19. Geiger PC, Cody MJ, Macken RL, Sieck GC. Maximum specific force depends on myosin heavy chain content in rat diaphragm muscle fibers. J Appl Physiol 89:695-703, 2000. (Pubitemid 30637120)
20. Geiger PC, Cody MJ, Sieck GC. Force-calcium relationship depends on myosin heavy chain and troponin isoforms in rat diaphragm muscle fibers. J Appl Physiol 87:1894-1900, 1999.
21. Gordon T, Thomas CK, Munson JB, Stein RB. The resilience of the size principle in the organization of motor unit properties in normal and reinnervated adult skeletal muscles. Can J Physiol Pharmacol 82:645-661, 2004. (Pubitemid 40065110)
22. Gosker HR, Engelen MP, Van Mameren H, Van Dijk PJ, Van Der Vusse GJ, Wouters EF, Schols AM. Muscle fiber type IIX atrophy is involved in the loss of fat-free mass in chronic obstructive pulmonary disease. Am J Clin Nutr 76:113-119, 2002. (Pubitemid 34686556)
23. Gosker HR, Kubat B, Schaart G, Van Der Vusse GJ, Wouters EF, Schols AM. Myopathological features in skeletal muscle of patients with chronic obstructive pulmonary disease. Eur Respir J 22:280-285, 2003. (Pubitemid 36986998)
24. Hamm TM, Nemeth PM, Solanki L, Gordon DA, Reinking RM, Stuart DG. Association between biochemical and physiological properties in single motor units. Muscle Nerve 11:245-254, 1988. (Pubitemid 18087363)
25. Hemmerling TM, Schmidt J, Wolf T, Hanusa C, Siebzehnruebl E, Schmitt H. Intramuscular versus surface electromyography of the diaphragm for determining neuromuscular blockade. Anesth Analg 92:106-111, 2001. (Pubitemid 32039187)
26. Henneman E. Relation between size of neurons and their susceptibility to discharge. Science 126:1345-1347, 1957.
27. Henneman E, Olson CB. Relations between structure and function in the design of skeletal muscles. J Neurophysiol 28:581-598, 1965.
28. Henneman E, Somjen G, Carpenter DO. Functional significance of cell size in spinal motoneurons. J Neurophysiol 28:560-580, 1965.
29. Hopkinson NS, Tennant RC, Dayer MJ, Swallow EB, Hansel TT, Moxham J, Polkey MI. A prospective study of decline in fat free mass and skeletal muscle strength in chronic obstructive pulmonary disease. Respir Res 8:25, 2007.
30. Iscoe S, Dankoff J, Migicovsky R, Polosa C. Recruitment and discharge frequency of phrenic motoneurones during inspiration. Respir Physiol 26:113-128, 1976.
31. Jodkowski JS, Viana F, Dick TE, Berger AJ. Electrical properties of phrenic motoneurons in the cat: correlation with inspiratory drive. J Neurophysiol 58:105-124, 1987. (Pubitemid 17095166)
32. Jodkowski JS, Viana F, Dick TE, Berger AJ. Repetitive firing properties of phrenic motoneurons in the cat. J Neurophysiol 60:687-702, 1988.
33. Kernell D. The Motoneurone and Its Muscle Fibres. New York: Oxford Univ. Press, 2006.
34. Levine S, Nguyen T, Kaiser LR, Rubinstein NA, Maislin G, Gregory C, Rome LC, Dudley GA, Sieck GC, Shrager JB. Human diaphragm remodeling associated with chronic obstructive pulmonary disease: clinical implications. Am J Respir Crit Care Med 168:706-713, 2003. (Pubitemid 37175973)
35. Lewis MI, Sieck GC. Effect of acute nutritional deprivation on diaphragm structure and function. J Appl Physiol 68:1938-1944, 1990. (Pubitemid 20183080)
36. Lewis MI, Zhan WZ, Sieck GC. Adaptations of the diaphragm in emphysema. J Appl Physiol 72:934-943, 1992.
37. Luthje L, Raupach T, Michels H, Unsold B, Hasenfuss G, Kogler H, Andreas S. Exercise intolerance and systemic manifestations of pulmonary emphysema in a mouse model. Respir Res 10:7, 2009.
38. Mantilla CB, Seven YB, Zhan WZ, Sieck GC. Diaphragm motor unit recruitment in rats. Respir Physiol Neurobiol 173:101-106, 2010.
39. Mantilla CB, Sieck GC. Phrenic motor unit recruitment during ventilatory and non-ventilatory behaviors. Respir Physiol Neurobiol 179:57-63, 2011.
40. McPhedran AM, Wuerker RB, Henneman E. Properties of motor units in a homogeneous red muscle (soleus) of the cat. J Neurophysiol 28:71-84, 1965.
41. Mendell LM. The size principle: a rule describing the recruitment of motoneurons. J Neurophysiol 93:3024-3026, 2005. (Pubitemid 40720879)
42. Miyata H, Zhan WZ, Prakash YS, Sieck GC. Myoneural interactions affect diaphragm muscle adaptations to inactivity. J Appl Physiol 79:1640-1649, 1995.
43. Nemeth PM, Solanki L, Gordon DA, Hamm TM, Reinking RM, Stuart DG. Uniformity of metabolic enzymes within individual motor units. J Neurosci 6:892-898, 1986. (Pubitemid 16134927)
44. Nguyen T, Rubinstein NA, Vijayasarathy C, Rome LC, Kaiser LR, Shrager JB, Levine S. Effect of chronic obstructive pulmonary disease on calcium pump ATPase expression in human diaphragm. J Appl Physiol 98:2004-2010, 2005. (Pubitemid 40726890)
45. Nguyen T, Shrager J, Kaiser L, Mei L, Daood M, Watchko J, Rubinstein N, Levine S. Developmental myosin heavy chains in the adult human diaphragm: coexpression patterns and effect of COPD. J Appl Physiol 88:1446-1456, 2000. (Pubitemid 30217448)
46. Ottenheijm CA, Heunks LM, Hafmans T, Van Der Ven PF, Benoist C, Zhou H, Labeit S, Granzier HL, Dekhuijzen PN. Titin and diaphragm dysfunction in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 173:527-534, 2006.
47. Ottenheijm CA, Heunks LM, Sieck GC, Zhan WZ, Jansen SM, Degens H, De Boo T, Dekhuijzen PN. Diaphragm dysfunction in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 172:200-205, 2005. (Pubitemid 40981194)
48. Oyer LM, Knuth SL, Ward DK, Bartlett DJ. Patterns of neural and muscular electrical activity in costal and crural portions of the diaphragm. J Appl Physiol 66:2092-2100, 1989. (Pubitemid 19142356)
49. Prakash YS, Mantilla CB, Zhan WZ, Smithson KG, Sieck GC. Phrenic motoneuron morphology during rapid diaphragm muscle growth. J Appl Physiol 89:563-572, 2000. (Pubitemid 30637103)
50. Reid WD, Wiggs BR, Pare PD, Pardy RL. Fiber type and regional differences in oxidative capacity and glycogen content in the hamster diaphragm. Am Rev Respir Dis 146:1266-1271, 1992.
51. Seven YB, Mantilla CB, Zhan WZ, Sieck GC. Non-stationarity and power spectral shifts in EMG activity reflect motor unit recruitment in rat diaphragm muscle. Respir Physiol Neurobiol 185:400-409, 2013.
52. Seymour JM, Ward K, Raffique A, Steier JS, Sidhu PS, Polkey MI, Moxham J, Rafferty GF. Quadriceps and ankle dorsiflexor strength in chronic obstructive pulmonary disease. Muscle Nerve 46:548-554, 2012.
53. Seymour JM, Ward K, Sidhu PS, Puthucheary Z, Steier J, Jolley CJ, Rafferty G, Polkey MI, Moxham J. Ultrasound measurement of rectus femoris cross-sectional area and the relationship with quadriceps strength in COPD. Thorax 64:418-423, 2009.
54. Sieck GC. Diaphragm muscle: structural and functional organization. Clin Chest Med 9:195-210, 1988.
55. Sieck GC. Neural control of the inspiratory pump. News Physiol Sci 6:260-264, 1991.
56. Sieck GC. Organization and recruitment of diaphragm motor units. In: The Thorax, edited by Roussos C. New York: Dekker, 1995, p. 783-820.
57. Sieck GC. Physiological effects of diaphragm muscle denervation and disuse. Clin Chest Med 15:641-659, 1994. (Pubitemid 24371952)
58. Sieck GC, Fournier M. Developmental aspects of diaphragm muscle cells: Structural and functional organization. In: Developmental Neurobiology of Breathing, edited by Haddad GG, Farber JP. New York: Dekker, 1991, p. 375-428.
59. Sieck GC, Fournier M. Diaphragm motor unit recruitment during ventilatory and nonventilatory behaviors. J Appl Physiol 66:2539-2545, 1989. (Pubitemid 19164947)
60. Sieck GC, Fournier M, Enad JG. Fiber type composition of muscle units in the cat diaphragm. Neurosci Lett 97:29-34, 1989. (Pubitemid 19048906)
61. Sieck GC, Fournier M, Prakash YS, Blanco CE. Myosin phenotype and SDH enzyme variability among motor unit fibers. J Appl Physiol 80:2179-2189, 1996. (Pubitemid 26243800)
62. Sieck GC, Lewis MI, Blanco CE. Effects of undernutrition on diaphragm fiber size, SDH activity, and fatigue resistance. J Appl Physiol 66:2196-2205, 1989. (Pubitemid 19142370)
63. Sieck GC, Prakash YS. Cross bridge kinetics in respiratory muscles. Eur Respir J 10:2147-2158, 1997. (Pubitemid 27406457)
64. Sinderby C, Beck J, Spahija J, Weinberg J, Grassino A. Voluntary activation of the human diaphragm in health and disease. J Appl Physiol 85:2146-2158, 1998. (Pubitemid 28558071)
65. Su CK, Mellen NM, Feldman JL. Intrinsic and extrinsic factors affecting phrenic motoneuronal excitability in neonatal rats. Brain Res 774:62-68, 1997. (Pubitemid 28007884)
66. Sypert GW, Munson JB. Basis of segmental motor control: Motoneuron size or motor unit type? Neurosurgery 8:608-621, 1981.
67. Walmsley B, Hodgson JA, Burke RE. Forces produced by medial gastrocnemius and soleus muscles during locomotion in freely moving cats. J Neurophysiol 41:1203-1216, 1978. (Pubitemid 9011388)
68. Zajac FE, Faden JS. Relationship among recruitment order, axonal conduction velocity, and muscle-unit properties of type-identified motor units in cat plantaris muscle. J Neurophysiol 53:1303-1322, 1985. (Pubitemid 15033047)
69. Zhan WZ, Miyata H, Prakash YS, Sieck GC. Metabolic and phenotypic adaptations of diaphragm muscle fibers with inactivation. J Appl Physiol 82:1145-1153, 1997. (Pubitemid 27172316)