Mortality and ratio of blood products used in patients with severe trauma [1]

JAMA - Journal of the American Medical Association

Volumn 313, Issue 20, 2015, Pages 2077-2078

  McCurdy, Michael T ^a   Liew Spilger, Alyson ^b   Walsh, Mark ^b  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b is an assistant professor of nursing at Bethel College   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FRESH FROZEN PLASMA;

BLOOD CLOTTING DISORDER; BLUNT TRAUMA; ERYTHROCYTE TRANSFUSION; EXSANGUINATION; HEMATOLOGICAL PARAMETERS; HEMOSTASIS; HUMAN; INJURY; LETTER; MORTALITY; PENETRATING TRAUMA; PLASMA TRANSFUSION; PRIORITY JOURNAL; RATIO FOR UNITS OF PLASMA AND PLATELETS TO RED BLOOD CELLS; RESUSCITATION; THROMBOCYTE DYSFUNCTION; THROMBOCYTE TRANSFUSION; THROMBOELASTOGRAPH; TRAFFIC ACCIDENT; BLOOD COMPONENT THERAPY; FEMALE; MALE; PROCEDURES; SHOCK, HEMORRHAGIC; WOUNDS AND INJURIES;

BLOOD COMPONENT TRANSFUSION; EXSANGUINATION; FEMALE; HUMANS; MALE; SHOCK, HEMORRHAGIC; WOUNDS AND INJURIES;

EID: 84929928032     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/jama.2015.4421     Document Type: Letter

References (5)

1. Holcomb JB, Tilley BC, Baraniuk S, et al; PROPPR Study Group. Transfusion of plasma, platelets, and red blood cells in a 1:1:1 vs a 1:1:2 ratio and mortality in patients with severe trauma: the PROPPR randomized clinical trial. JAMA. 2015; 313(5):471-482.
2. Mitra B, Cameron PA, Gruen RL, Mori A, Fitzgerald M, Street A. The definition of massive transfusion in trauma: a critical variable in examining evidence for resuscitation. Eur J Emerg Med. 2011;18(3):137-142.
3. Schochl H, Nienaber U, Maegele M, et al. Transfusion in trauma: thromboelastometry-guided coagulation factor concentrate-based therapy versus standard fresh frozen plasma-based therapy. Crit Care. 2011;15(2):R83.
4. Zink KA, Sambasivan CN, Holcomb JB, Chisholm G, Schreiber MA. A high ratio of plasma and platelets to packed red blood cells in the first 6 hours of massive transfusion improves outcomes in a large multicenter study. Am J Surg. 2009;197(5):565-570.
5. Wohlauer MV, Moore EE, Thomas S, et al. Early platelet dysfunction: an unrecognized role in the acute coagulopathy of trauma. J AmColl Surg. 2012;214 (5):739-746.