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Volumn 19, Issue 10, 2014, Pages 1076-1083

Age-specific changes in intrinsic breast cancer subtypes: A focus on older women

Author keywords

Age; Breast cancer; Elderly; Gene microarray

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; PROGESTERONE RECEPTOR; ERBB2 PROTEIN, HUMAN; ESTROGEN RECEPTOR;

EID: 84929918938     PISSN: 10837159     EISSN: 1549490X     Source Type: Journal    
DOI: 10.1634/theoncologist.2014-0184     Document Type: Article
Times cited : (122)

References (41)
  • 2
    • 0034607235 scopus 로고    scopus 로고
    • Tumor characteristics and clinical outcome of elderly womenwith breast cancer
    • Diab SG, Elledge RM, Clark GM. Tumor characteristics and clinical outcome of elderly womenwith breast cancer. J Natl Cancer Inst 2000; 92: 550-556.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 550-556
    • Diab, S.G.1    Elledge, R.M.2    Clark, G.M.3
  • 3
    • 44649165728 scopus 로고    scopus 로고
    • A significant proportion of elderly patients develop hormonedependant "luminal-B" tumours associated with aggressive characteristics
    • Durbecq V, Ameye L, Veys I et al. A significant proportion of elderly patients develop hormonedependant "luminal-B" tumours associated with aggressive characteristics. Crit Rev Oncol Hematol 2008; 67: 80-92.
    • (2008) Crit Rev Oncol Hematol , vol.67 , pp. 80-92
    • Durbecq, V.1    Ameye, L.2    Veys, I.3
  • 4
    • 0035816019 scopus 로고    scopus 로고
    • Cancer screening in elderly patients: A framework for individualized decision making
    • Walter LC, Covinsky KE. Cancer screening in elderly patients: A framework for individualized decision making. JAMA 2001; 285: 2750-2756.
    • (2001) JAMA , vol.285 , pp. 2750-2756
    • Walter, L.C.1    Covinsky, K.E.2
  • 5
    • 84866888703 scopus 로고    scopus 로고
    • PAM50 breast cancer subtyping by RT-qPCR and concordance with standard clinical molecular markers
    • Bastien RR, Rodriguez-Lescure A, Ebbert MT et al. PAM50 breast cancer subtyping by RT-qPCR and concordance with standard clinical molecular markers. BMC Med Genomics 2012; 5: 44.
    • (2012) BMC Med Genomics , vol.5 , pp. 44
    • Bastien, R.R.1    Rodriguez-Lescure, A.2    Ebbert, M.T.3
  • 6
    • 78049453780 scopus 로고    scopus 로고
    • A comparison of PAM50 intrinsic subtyping with immunohistochemistry and clinical prognostic factors in tamoxifen-treated estrogen receptorpositive breast cancer
    • Nielsen TO, Parker JS, Leung S et al. A comparison of PAM50 intrinsic subtyping with immunohistochemistry and clinical prognostic factors in tamoxifen-treated estrogen receptorpositive breast cancer. Clin Cancer Res 2010; 16: 5222-5232.
    • (2010) Clin Cancer Res , vol.16 , pp. 5222-5232
    • Nielsen, T.O.1    Parker, J.S.2    Leung, S.3
  • 7
    • 84872550777 scopus 로고    scopus 로고
    • Prognostic significance of progesterone receptor-positive tumor cells within immunohistochemically defined luminal a breast cancer
    • Prat A, Cheang MC, Martin M et al. Prognostic significance of progesterone receptor-positive tumor cells within immunohistochemically defined luminal a breast cancer. J Clin Oncol 2013; 31: 203-209.
    • (2013) J Clin Oncol , vol.31 , pp. 203-209
    • Prat, A.1    Cheang, M.C.2    Martin, M.3
  • 8
    • 79959268722 scopus 로고    scopus 로고
    • Randomized phase II neoadjuvant comparison between letrozole, anastrozole, and exemestane for postmenopausal women with estrogen receptor-rich stage 2 to 3 breast cancer: Clinical and biomarker outcomes and predictive value of the baseline PAM50-based intrinsic subtype-ACOSOGZ1031
    • Ellis MJ, Suman VJ, Hoog J et al. Randomized phase II neoadjuvant comparison between letrozole, anastrozole, and exemestane for postmenopausal women with estrogen receptor-rich stage 2 to 3 breast cancer: Clinical and biomarker outcomes and predictive value of the baseline PAM50-based intrinsic subtype-ACOSOGZ1031. J Clin Oncol 2011; 29: 2342-2349.
    • (2011) J Clin Oncol , vol.29 , pp. 2342-2349
    • Ellis, M.J.1    Suman, V.J.2    Hoog, J.3
  • 9
    • 49149119336 scopus 로고    scopus 로고
    • Young ageat diagnosis correlates withworseprognosisand defines a subset of breast cancers with shared patterns of gene expression
    • Anders CK, Hsu DS, Broadwater G et al. Young ageat diagnosis correlates withworseprognosisand defines a subset of breast cancers with shared patterns of gene expression. J Clin Oncol 2008; 26: 3324-3330.
    • (2008) J Clin Oncol , vol.26 , pp. 3324-3330
    • Anders, C.K.1    Hsu, D.S.2    Broadwater, G.3
  • 10
    • 84884762173 scopus 로고    scopus 로고
    • Comparison of PAM50 risk of recurrence score with oncotype DX and IHC4 for predicting risk of distant recurrence after endocrine therapy
    • Dowsett M, Sestak I, Lopez-Knowles E et al. Comparison of PAM50 risk of recurrence score with oncotype DX and IHC4 for predicting risk of distant recurrence after endocrine therapy. J Clin Oncol 2013; 31: 2783-2790.
    • (2013) J Clin Oncol , vol.31 , pp. 2783-2790
    • Dowsett, M.1    Sestak, I.2    Lopez-Knowles, E.3
  • 11
    • 40949121882 scopus 로고    scopus 로고
    • Basal-like breast cancer defined by five biomarkers has superior prognostic value than triple-negative phenotype
    • Cheang MC, Voduc D, Bajdik C et al. Basal-like breast cancer defined by five biomarkers has superior prognostic value than triple-negative phenotype. Clin Cancer Res 2008; 14: 1368-1376.
    • (2008) Clin Cancer Res , vol.14 , pp. 1368-1376
    • Cheang, M.C.1    Voduc, D.2    Bajdik, C.3
  • 12
    • 84862584058 scopus 로고    scopus 로고
    • Whole-genome analysis informs breast cancer response to aromatase inhibition
    • Ellis MJ, Ding L, Shen D et al. Whole-genome analysis informs breast cancer response to aromatase inhibition. Nature 2012; 486: 353-360.
    • (2012) Nature , vol.486 , pp. 353-360
    • Ellis, M.J.1    Ding, L.2    Shen, D.3
  • 13
    • 84877028141 scopus 로고    scopus 로고
    • Comprehensive molecular portraits of human breast tumours
    • Cancer Genome Atlas Network. Comprehensive molecular portraits of human breast tumours. Nature 2012; 490: 61-70.
    • (2012) Nature , vol.490 , pp. 61-70
    • Cancer Genome Atlas Network1
  • 14
    • 80052223077 scopus 로고    scopus 로고
    • MicroRNA-associated progression pathways and potential therapeutic targets identified by integrated mRNA and microRNA expression profiling in breast cancer
    • Buffa FM, Camps C, Winchester L et al. MicroRNA-associated progression pathways and potential therapeutic targets identified by integrated mRNA and microRNA expression profiling in breast cancer. Cancer Res 2011; 71: 5635-5645.
    • (2011) Cancer Res , vol.71 , pp. 5635-5645
    • Buffa, F.M.1    Camps, C.2    Winchester, L.3
  • 15
    • 38949115186 scopus 로고    scopus 로고
    • Agespecific differences in oncogenic pathway deregulation seen in human breast tumors
    • Anders CK, Acharya CR, Hsu DS et al. Agespecific differences in oncogenic pathway deregulation seen in human breast tumors. PLoS One 2008; 3: e1373.
    • (2008) PLoS One , vol.3
    • Anders, C.K.1    Acharya, C.R.2    Hsu, D.S.3
  • 16
    • 13844310310 scopus 로고    scopus 로고
    • Gene-expression profilesto predictdistantmetastasis oflymph-nodenegative primary breast cancer
    • WangY, Klijn JG, Zhang Y et al. Gene-expression profilesto predictdistantmetastasis oflymph-nodenegative primary breast cancer. Lancet 2005; 365: 671-679.
    • (2005) Lancet , vol.365 , pp. 671-679
    • Wang, Y.1    Klijn, J.G.2    Zhang, Y.3
  • 17
    • 33751261643 scopus 로고    scopus 로고
    • Genetic reclassification of histologic grade delineates new clinical subtypes of breast cancer
    • Ivshina AV, George J, Senko O et al. Genetic reclassification of histologic grade delineates new clinical subtypes of breast cancer. Cancer Res 2006; 66: 10292-10301.
    • (2006) Cancer Res , vol.66 , pp. 10292-10301
    • Ivshina, A.V.1    George, J.2    Senko, O.3
  • 18
    • 79955798310 scopus 로고    scopus 로고
    • A genomic predictor of response and survival following taxaneanthracycline chemotherapy for invasive breast cancer
    • Hatzis C, Pusztai L, Valero V et al. A genomic predictor of response and survival following taxaneanthracycline chemotherapy for invasive breast cancer. JAMA 2011; 305: 1873-1881.
    • (2011) JAMA , vol.305 , pp. 1873-1881
    • Hatzis, C.1    Pusztai, L.2    Valero, V.3
  • 19
    • 23144461051 scopus 로고    scopus 로고
    • Genes that mediate breast cancer metastasis to lung
    • Minn AJ, Gupta GP, Siegel PM et al. Genes that mediate breast cancer metastasis to lung. Nature 2005; 436: 518-524.
    • (2005) Nature , vol.436 , pp. 518-524
    • Minn, A.J.1    Gupta, G.P.2    Siegel, P.M.3
  • 20
    • 33144462268 scopus 로고    scopus 로고
    • Gene expression profiling in breast cancer: Understanding the molecular basis of histologic grade to improve prognosis
    • Sotiriou C, Wirapati P, Loi S et al. Gene expression profiling in breast cancer: Understanding the molecular basis of histologic grade to improve prognosis. J Natl Cancer Inst 2006; 98: 262-272.
    • (2006) J Natl Cancer Inst , vol.98 , pp. 262-272
    • Sotiriou, C.1    Wirapati, P.2    Loi, S.3
  • 21
    • 78049308800 scopus 로고    scopus 로고
    • Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer
    • Prat A, Parker JS, KarginovaO et al. Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer. Breast Cancer Res 2010; 12: R68.
    • (2010) Breast Cancer Res , vol.12 , pp. R68
    • Prat, A.1    Parker, J.S.2    Karginova, O.3
  • 22
    • 84861527388 scopus 로고    scopus 로고
    • The genomic and transcriptomic architecture of 2, 000 breast tumours reveals novel subgroups
    • Curtis C, Shah SP, Chin SF et al. The genomic and transcriptomic architecture of 2, 000 breast tumours reveals novel subgroups. Nature 2012; 486: 346-352.
    • (2012) Nature , vol.486 , pp. 346-352
    • Curtis, C.1    Shah, S.P.2    Chin, S.F.3
  • 23
    • 62449131093 scopus 로고    scopus 로고
    • Supervised risk predictor of breast cancer based on intrinsic subtypes
    • Parker JS, Mullins M, Cheang MC et al. Supervised risk predictor of breast cancer based on intrinsic subtypes. J Clin Oncol 2009; 27: 1160-1167.
    • (2009) J Clin Oncol , vol.27 , pp. 1160-1167
    • Parker, J.S.1    Mullins, M.2    Cheang, M.C.3
  • 25
    • 84865125800 scopus 로고    scopus 로고
    • PAM50 assay and the three-gene model for identifying the major and clinically relevant molecular subtypes of breast cancer
    • Prat A, Parker JS, Fan C, Perou CM. PAM50 assay and the three-gene model for identifying the major and clinically relevant molecular subtypes of breast cancer. Breast Cancer Res Treat 2012; 135: 301-306.
    • (2012) Breast Cancer Res Treat , vol.135 , pp. 301-306
    • Prat, A.1    Parker, J.S.2    Fan, C.3    Perou, C.M.4
  • 26
    • 78951482208 scopus 로고    scopus 로고
    • Deconstructing the molecular portraits of breast cancer
    • Prat A, Perou CM. Deconstructing the molecular portraits of breast cancer. Mol Oncol 2011; 5: 5-23.
    • (2011) Mol Oncol , vol.5 , pp. 5-23
    • Prat, A.1    Perou, C.M.2
  • 27
    • 84863728650 scopus 로고    scopus 로고
    • Tumour biomarker expression relative to age and molecular subtypes of invasive breast cancer
    • Morrison DHRD, Rahardja D, King E et al. Tumour biomarker expression relative to age and molecular subtypes of invasive breast cancer. Br J Cancer 2012; 107: 382-387.
    • (2012) Br J Cancer , vol.107 , pp. 382-387
    • Morrison, D.H.R.D.1    Rahardja, D.2    King, E.3
  • 28
    • 35248837469 scopus 로고    scopus 로고
    • Molecular breast cancer subtypes in premenopausal and postmenopausal African-American women: Age-specific prevalence and survival
    • Ihemelandu CULL, Leffall LD Jr., Dewitty RL et al. Molecular breast cancer subtypes in premenopausal and postmenopausal African-American women: Age-specific prevalence and survival. J Surg Res 2007; 143: 109-118.
    • (2007) J Surg Res , vol.143 , pp. 109-118
    • Ihemelandu, C.U.L.L.1    Leffall, L.D.2    Dewitty, R.L.3
  • 29
    • 81155123192 scopus 로고    scopus 로고
    • Influence of comorbidities and age on risk of death without recurrence: Aretrospective analysis of the arimidex, tamoxifen alone or in combination trial
    • Ring A, Sestak I, Baum M et al. Influence of comorbidities and age on risk of death without recurrence: Aretrospective analysis of the arimidex, tamoxifen alone or in combination trial. J Clin Oncol 2011; 29: 4266-4272.
    • (2011) J Clin Oncol , vol.29 , pp. 4266-4272
    • Ring, A.1    Sestak, I.2    Baum, M.3
  • 30
    • 20044388527 scopus 로고    scopus 로고
    • Adjuvant chemotherapy in older and younger women with lymph node-positive breast cancer
    • Muss HB, Woolf S, Berry D et al. Adjuvant chemotherapy in older and younger women with lymph node-positive breast cancer. JAMA 2005; 293: 1073-1081.
    • (2005) JAMA , vol.293 , pp. 1073-1081
    • Muss, H.B.1    Woolf, S.2    Berry, D.3
  • 31
    • 79951962586 scopus 로고    scopus 로고
    • Breast carcinomas arising at a young age: Unique biology or a surrogate for aggressive intrinsic subtypes?
    • Anders CKFC, Fan C, Parker JS et al. Breast carcinomas arising at a young age: Unique biology or a surrogate for aggressive intrinsic subtypes? J Clin Oncol 2011; 29: e18-e20.
    • (2011) J Clin Oncol , vol.29 , pp. e18-e20
    • Anders, C.K.F.C.1    Fan, C.2    Parker, J.S.3
  • 32
    • 33744814477 scopus 로고    scopus 로고
    • Gene expression and benefit of chemotherapy in women with nodenegative, estrogen receptor-positive breast cancer
    • Paik S, Tang G, Shak S et al. Gene expression and benefit of chemotherapy in women with nodenegative, estrogen receptor-positive breast cancer. J Clin Oncol 2006; 24: 3726-3734.
    • (2006) J Clin Oncol , vol.24 , pp. 3726-3734
    • Paik, S.1    Tang, G.2    Shak, S.3
  • 33
    • 84894092094 scopus 로고    scopus 로고
    • Long-term impact of the 70-gene signature on breast cancer outcome
    • Drukker CA, van Tinteren H, Schmidt MK et al. Long-term impact of the 70-gene signature on breast cancer outcome. Breast Cancer Res Treat 2014; 143: 587-592.
    • (2014) Breast Cancer Res Treat , vol.143 , pp. 587-592
    • Drukker, C.A.1    van Tinteren, H.2    Schmidt, M.K.3
  • 34
    • 84892776195 scopus 로고    scopus 로고
    • Research-based PAM50 subtype predictor identifies higher responses and improved survival outcomes in HER2-positive breast cancer in the NOAH study
    • Prat A, Bianchini G, Thomas M et al. Research-based PAM50 subtype predictor identifies higher responses and improved survival outcomes in HER2-positive breast cancer in the NOAH study. Clin Cancer Res 2014; 20: 511-521.
    • (2014) Clin Cancer Res , vol.20 , pp. 511-521
    • Prat, A.1    Bianchini, G.2    Thomas, M.3
  • 35
    • 79958766471 scopus 로고    scopus 로고
    • Association between breast cancer subtypes and response to neoadjuvant anastrozole
    • Dunbier AK, Anderson H, Ghazoui Z et al. Association between breast cancer subtypes and response to neoadjuvant anastrozole. Steroids 2011; 76: 736-740.
    • (2011) Steroids , vol.76 , pp. 736-740
    • Dunbier, A.K.1    Anderson, H.2    Ghazoui, Z.3
  • 36
    • 84865191389 scopus 로고    scopus 로고
    • Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: Results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657)
    • Esserman LJ, Berry DA, Cheang MC et al. Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: Results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657). Breast Cancer Res Treat 2012; 132: 1049-1062.
    • (2012) Breast Cancer Res Treat , vol.132 , pp. 1049-1062
    • Esserman, L.J.1    Berry, D.A.2    Cheang, M.C.3
  • 37
    • 84879420977 scopus 로고    scopus 로고
    • PAM50 proliferation score as a predictor of weekly paclitaxel benefit in breast cancer
    • Martín M, Prat A, Rodríguez-Lescure A et al. PAM50 proliferation score as a predictor of weekly paclitaxel benefit in breast cancer. BreastCancer Res Treat 2013; 138: 457-466.
    • (2013) BreastCancer Res Treat , vol.138 , pp. 457-466
    • Martín, M.1    Prat, A.2    Rodríguez-Lescure, A.3
  • 38
    • 84874586547 scopus 로고    scopus 로고
    • Adjuvant therapy of breast cancer in women 70 years of age and older: Tough decisions, high stakes
    • Jones EL, Leak A, MussHB. Adjuvant therapy of breast cancer in women 70 years of age and older: Tough decisions, high stakes. Oncology (Williston Park) 2012; 26: 793-801.
    • (2012) Oncology (Williston Park) , vol.26 , pp. 793-801
    • Jones, E.L.1    Leak, A.2    Muss, H.B.3
  • 39
    • 84862909269 scopus 로고    scopus 로고
    • Prognostic indices for older adults: A systematic review
    • Yourman LCLS, Lee SJ, Schonberg MA et al. Prognostic indices for older adults: A systematic review. JAMA 2012; 307: 182-192.
    • (2012) JAMA , vol.307 , pp. 182-192
    • Yourman, L.C.L.S.1    Lee, S.J.2    Schonberg, M.A.3
  • 40
    • 0038662715 scopus 로고    scopus 로고
    • Participation of patients 65 years of age or older in cancer clinical trials
    • Lewis JHKM, Kilgore ML, Goldman DP et al. Participation of patients 65 years of age or older in cancer clinical trials. J Clin Oncol 2003; 21: 1383-1389.
    • (2003) J Clin Oncol , vol.21 , pp. 1383-1389
    • Lewis, J.H.K.M.1    Kilgore, M.L.2    Goldman, D.P.3
  • 41
    • 84898456463 scopus 로고    scopus 로고
    • Eribulin Monotherapy in Patients Aged 70 Years and Older With Metastatic Breast Cancer
    • Hyman Muss, Javier Cortes, Linda T. Vahdat et al. Eribulin Monotherapy in Patients Aged 70 Years and Older With Metastatic Breast Cancer. The Oncologist 2014; 19: 318-327.
    • (2014) The Oncologist , vol.19 , pp. 318-327
    • Muss, H.1    Cortes, J.2    Vahdat, L.T.3


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