메뉴 건너뛰기




Volumn 26, Issue 9, 2012, Pages

Adjuvant therapy of breast cancer in women 70 years of age and older: Tough decisions, high stakes

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE; AROMATASE INHIBITOR; CAPECITABINE; CARBOPLATIN; CYCLOPHOSPHAMIDE; DENOSUMAB; DOCETAXEL; DOXORUBICIN; EPIRUBICIN; FLUOROURACIL; METHOTREXATE; PACLITAXEL; TAMOXIFEN; TRASTUZUMAB;

EID: 84874586547     PISSN: 08909091     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (18)

References (45)
  • 1
    • 84855273791 scopus 로고    scopus 로고
    • National Center for Health and Statistics. Available at
    • National Center for Health and Statistics. Tables on trends in health and aging; life expectancy. 2012. Available at: http://www.cdc.gov/nchs/fastats/lifexpec.Htm.
    • (2012) Tables on trends in health and aging; life expectancy
  • 3
    • 27244434470 scopus 로고    scopus 로고
    • Effect of screening and adjuvant therapy on mortality from breast cancer
    • Berry DA, Cronin KA, Plevritis SK, et al. Effect of screening and adjuvant therapy on mortality from breast cancer. N Engl J Med. 2005;353:1784-92.
    • (2005) N Engl J Med. , vol.353 , pp. 1784-1792
    • Berry, D.A.1    Cronin, K.A.2    Plevritis, S.K.3
  • 4
    • 83355174078 scopus 로고    scopus 로고
    • Improvement in breast cancer outcomes over time: Are older women missing out?
    • Smith BD, Jiang J, McLaughlin SS, et al. Improvement in breast cancer outcomes over time: are older women missing out? J Clin Oncol. 2011; 29:4647-53.
    • (2011) J Clin Oncol. , vol.29 , pp. 4647-4653
    • Smith, B.D.1    Jiang, J.2    McLaughlin, S.S.3
  • 5
    • 72049090936 scopus 로고    scopus 로고
    • Screening for breast cancer: An update for the U.S. Preventive Services Task Force
    • Nelson HD, Tyne K, Naik A, et al. Screening for breast cancer: an update for the U.S. Preventive Services Task Force. Ann Intern Med. 2009;151:727-37.
    • (2009) Ann Intern Med. , vol.151 , pp. 727-737
    • Nelson, H.D.1    Tyne, K.2    Naik, A.3
  • 6
    • 4644265882 scopus 로고    scopus 로고
    • Compliance with consensus recommendations for systemic therapy is associated with improved survival of women with node-negative breast cancer
    • Hebert-Croteau N, Brisson J, Latreille J, et al. Compliance with consensus recommendations for systemic therapy is associated with improved survival of women with node-negative breast cancer. J Clin Oncol. 2004;22:3685-93.
    • (2004) J Clin Oncol. , vol.22 , pp. 3685-3693
    • Hebert-Croteau, N.1    Brisson, J.2    Latreille, J.3
  • 7
    • 84859140429 scopus 로고    scopus 로고
    • Management of elderly patients with breast cancer: Updated recommendations of the International Society of Geriatric Oncology (SIOG) and European Society of Breast Cancer Specialists (EUSOMA)
    • Biganzoli L, Wildiers H, Oakman C, et al. Management of elderly patients with breast cancer: updated recommendations of the International Society of Geriatric Oncology (SIOG) and European Society of Breast Cancer Specialists (EUSOMA). Lancet Oncol. 2012;13:e148-60.
    • (2012) Lancet Oncol. , vol.13
    • Biganzoli, L.1    Wildiers, H.2    Oakman, C.3
  • 8
    • 84961396700 scopus 로고    scopus 로고
    • Adjuvant therapy for older women with early-stage breast cancer: Treatment selection in a complex population
    • Alexandria, Va: American Society of Clinical Oncology
    • Owusu C, Hurria A, Muss HB. Adjuvant therapy for older women with early-stage breast cancer: treatment selection in a complex population; ASCO Educational Book. Alexandria, Va: American Society of Clinical Oncology, 2012; pp 3-9.
    • (2012) ASCO Educational Book , pp. 3-9
    • Owusu, C.1    Hurria, A.2    Muss, H.B.3
  • 9
    • 0035925169 scopus 로고    scopus 로고
    • Effect of age and comorbidity in postmenopausal breast cancer patients aged 55 years and older
    • Yancik R, Wesley MN, Ries LA, et al. Effect of age and comorbidity in postmenopausal breast cancer patients aged 55 years and older. JAMA. 2001;285:885-92.
    • (2001) JAMA. , vol.285 , pp. 885-892
    • Yancik, R.1    Wesley, M.N.2    Ries, L.A.3
  • 10
    • 4444315066 scopus 로고    scopus 로고
    • Probabilities of death from breast cancer and other causes among female breast cancer patients
    • Schairer C, Mink PJ, Carroll L, Devesa SS. Probabilities of death from breast cancer and other causes among female breast cancer patients. J Natl Cancer Inst. 2004;96:1311-21.
    • (2004) J Natl Cancer Inst. , vol.96 , pp. 1311-1321
    • Schairer, C.1    Mink, P.J.2    Carroll, L.3    Devesa, S.S.4
  • 11
    • 84862909269 scopus 로고    scopus 로고
    • Prognostic indices for older adults: A systematic review
    • Yourman LC, Lee SJ, Schonberg MA, et al. Prognostic indices for older adults: a systematic review. JAMA. 2012;307:182-92.
    • (2012) JAMA. , vol.307 , pp. 182-192
    • Yourman, L.C.1    Lee, S.J.2    Schonberg, M.A.3
  • 12
    • 79953836199 scopus 로고    scopus 로고
    • Implementing a geriatric assessment in cooperative group clinical cancer trials: CALGB 360401
    • Hurria A, Cirrincione CT, Muss HB, et al. Implementing a geriatric assessment in cooperative group clinical cancer trials: CALGB 360401. J Clin Oncol. 2011;29:1290-6.
    • (2011) J Clin Oncol. , vol.29 , pp. 1290-1296
    • Hurria, A.1    Cirrincione, C.T.2    Muss, H.B.3
  • 13
    • 84863026958 scopus 로고    scopus 로고
    • Comprehensive geriatric assessment and its clinical impact in oncology
    • Liu JJ, Extermann M. Comprehensive geriatric assessment and its clinical impact in oncology. Clin Geriatr Med. 2012;28:19.
    • (2012) Clin Geriatr Med. , vol.28 , pp. 19
    • Liu, J.J.1    Extermann, M.2
  • 14
    • 33644639190 scopus 로고    scopus 로고
    • Higher vulnerable elders survey scores predict death and functional decline in vulnerable older people
    • Min LC, Elliott MN, Wenger NS, Saliba D. Higher vulnerable elders survey scores predict death and functional decline in vulnerable older people. J Am Geriatr Soc. 2006;54:507-11.
    • (2006) J Am Geriatr Soc. , vol.54 , pp. 507-511
    • Min, L.C.1    Elliott, M.N.2    Wenger, N.S.3    Saliba, D.4
  • 15
    • 0034010518 scopus 로고    scopus 로고
    • Measuring comorbidity in older cancer patients
    • Extermann M. Measuring comorbidity in older cancer patients. Eur J Cancer. 2000;36:453-71.
    • (2000) Eur J Cancer. , vol.36 , pp. 453-471
    • Extermann, M.1
  • 16
    • 38049042806 scopus 로고    scopus 로고
    • Management of the frail elderly with breast cancer
    • Dittus K, Muss HB. Management of the frail elderly with breast cancer. Oncology (Williston Park). 2007;21:1727-34.
    • (2007) Oncology (Williston Park). , vol.21 , pp. 1727-1734
    • Dittus, K.1    Muss, H.B.2
  • 17
    • 33645512610 scopus 로고    scopus 로고
    • Surgery versus primary endocrine therapy for operable primary breast cancer in elderly women (70 years plus)
    • Hind D, Wyld L, Beverley CB, Reed MW. Surgery versus primary endocrine therapy for operable primary breast cancer in elderly women (70 years plus). Cochrane Database Syst Rev. 2006:CD004272.
    • (2006) Cochrane Database Syst Rev.
    • Hind, D.1    Wyld, L.2    Beverley, C.B.3    Reed, M.W.4
  • 18
    • 24644490871 scopus 로고    scopus 로고
    • Neoadjuvant treatment of postmenopausal breast cancer with anastrozole, tamoxifen, or both in combination: The immediate preoperative anastrozole, tamoxifen, or combined with tamoxifen (IMPACT) multicenter double-blind randomized trial
    • Smith IE, Dowsett M, Ebbs SR, et al. Neoadjuvant treatment of postmenopausal breast cancer with anastrozole, tamoxifen, or both in combination: the immediate preoperative anastrozole, tamoxifen, or combined with tamoxifen (IMPACT) multicenter double-blind randomized trial. J Clin Oncol. 2005; 23:5108-16.
    • (2005) J Clin Oncol. , vol.23 , pp. 5108-5116
    • Smith, I.E.1    Dowsett, M.2    Ebbs, S.R.3
  • 19
    • 4344707888 scopus 로고    scopus 로고
    • Tamoxifen with or without breast irradiation in women 50 years of age or older with early breast cancer
    • Fyles AW, McCready DR, Manchul LA, et al. Tamoxifen with or without breast irradiation in women 50 years of age or older with early breast cancer. N Engl J Med. 2004;351:963-70.
    • (2004) N Engl J Med. , vol.351 , pp. 963-970
    • Fyles, A.W.1    McCready, D.R.2    Manchul, L.A.3
  • 20
    • 4344628403 scopus 로고    scopus 로고
    • Lumpectomy plus tamoxifen with or without irradiation in women 70 years of age or older with early breast cancer
    • Hughes KS, Schnaper LA, Berry D, et al. Lumpectomy plus tamoxifen with or without irradiation in women 70 years of age or older with early breast cancer. N Engl J Med. 2004;351:971-7.
    • (2004) N Engl J Med. , vol.351 , pp. 971-977
    • Hughes, K.S.1    Schnaper, L.A.2    Berry, D.3
  • 21
    • 77955859047 scopus 로고    scopus 로고
    • Lumpectomy plus tamoxifen with or without irradiation in women age 70 or older with early breast cancer
    • and CALGB, ECOG, RTOG:;abstr 507
    • Hughes KS, Schnaper LA, Cirrincione C, et al, and CALGB, ECOG, RTOG: lumpectomy plus tamoxifen with or without irradiation in women age 70 or older with early breast cancer. J Clin Oncol. 2010;28(15s): abstr 507.
    • (2010) J Clin Oncol. , vol.28 , Issue.15 S
    • Hughes, K.S.1    Schnaper, L.A.2    Cirrincione, C.3
  • 22
    • 81055155920 scopus 로고    scopus 로고
    • Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: Meta-analysis of individual patient data for 10,801 women in 17 randomised trials
    • Darby S, McGale P, Correa C, et al. Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10,801 women in 17 randomised trials. Lancet. 2011;378:1707-16.
    • (2011) Lancet , vol.378 , pp. 1707-1716
    • Darby, S.1    McGale, P.2    Correa, C.3
  • 23
    • 77953248475 scopus 로고    scopus 로고
    • Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: A collaborative analysis of data for 10,159 cases from 12 studies
    • Blows FM, Driver KE, Schmidt MK, et al. Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: a collaborative analysis of data for 10,159 cases from 12 studies. PLoS Med. 2010; 7:e1000279.
    • (2010) PLoS Med. , vol.7
    • Blows, F.M.1    Driver, K.E.2    Schmidt, M.K.3
  • 24
    • 0029759541 scopus 로고    scopus 로고
    • Annual hazard rates of recurrence for breast cancer after primary therapy
    • Saphner T, Tormey DC, Gray R. Annual hazard rates of recurrence for breast cancer after primary therapy. J Clin Oncol. 1996;14:2738-46.
    • (1996) J Clin Oncol. , vol.14 , pp. 2738-2746
    • Saphner, T.1    Tormey, D.C.2    Gray, R.3
  • 25
    • 57449098840 scopus 로고    scopus 로고
    • Human epidermal growth factor receptor 2 overexpression as a prognostic factor in a large tissue microarray series of node-negative breast cancers
    • Chia S, Norris B, Speers C, et al. Human epidermal growth factor receptor 2 overexpression as a prognostic factor in a large tissue microarray series of node-negative breast cancers. J Clin Oncol. 2008; 26:5697-704.
    • (2008) J Clin Oncol. , vol.26 , pp. 5697-5704
    • Chia, S.1    Norris, B.2    Speers, C.3
  • 26
    • 19344364880 scopus 로고    scopus 로고
    • Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: An overview of the randomised trials
    • Early Breast Cancer Trialists' Collaborative Group (EBCTCG)
    • Early Breast Cancer Trialists' Collaborative Group (EBCTCG). Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials. Lancet. 2005;365:1687-717.
    • (2005) Lancet , vol.365 , pp. 1687-1717
  • 27
    • 84862242969 scopus 로고    scopus 로고
    • Is adjuvant chemotherapy useful for women with luminal A breast cancer?
    • Coates AS, Colleoni M, Goldhirsch A. Is adjuvant chemotherapy useful for women with luminal A breast cancer? J Clin Oncol. 2012;30:1260-3.
    • (2012) J Clin Oncol. , vol.30 , pp. 1260-1263
    • Coates, A.S.1    Colleoni, M.2    Goldhirsch, A.3
  • 28
    • 77951637777 scopus 로고    scopus 로고
    • Prediction of risk of distant recurrence using the 21-gene recurrence score in node-negative and node-positive postmenopausal patients with breast cancer treated with anastrozole or tamoxifen: A TransATAC study
    • Dowsett M, Cuzick J, Wale C, et al. Prediction of risk of distant recurrence using the 21-gene recurrence score in node-negative and node-positive postmenopausal patients with breast cancer treated with anastrozole or tamoxifen: a TransATAC study. J Clin Oncol. 2010;28:1829-34.
    • (2010) J Clin Oncol. , vol.28 , pp. 1829-1834
    • Dowsett, M.1    Cuzick, J.2    Wale, C.3
  • 29
    • 33744814477 scopus 로고    scopus 로고
    • Gene expression and benefit of chemotherapy in women with node-negative, estrogen receptor-positive breast cancer
    • Paik S, Tang G, Shak S, et al. Gene expression and benefit of chemotherapy in women with node-negative, estrogen receptor-positive breast cancer. J Clin Oncol 2006;24:3726-34.
    • (2006) J Clin Oncol , vol.24 , pp. 3726-3734
    • Paik, S.1    Tang, G.2    Shak, S.3
  • 30
    • 0035865149 scopus 로고    scopus 로고
    • Computer program to assist in making decisions about adjuvant therapy for women with early breast cancer
    • Ravdin PM, Siminoff LA, Davis GJ, et al. Computer program to assist in making decisions about adjuvant therapy for women with early breast cancer. J Clin Oncol. 2001;19:980-91.
    • (2001) J Clin Oncol. , vol.19 , pp. 980-991
    • Ravdin, P.M.1    Siminoff, L.A.2    Davis, G.J.3
  • 31
    • 39149107837 scopus 로고    scopus 로고
    • Predictors of tamoxifen discontinuation among older women with estrogen receptor-positive breast cancer
    • Owusu C, Buist DS, Field TS, et al. Predictors of tamoxifen discontinuation among older women with estrogen receptor-positive breast cancer. J Clin Oncol. 2008;26:549-55.
    • (2008) J Clin Oncol. , vol.26 , pp. 549-555
    • Owusu, C.1    Buist, D.S.2    Field, T.S.3
  • 32
    • 77955551055 scopus 로고    scopus 로고
    • American Society of Clinical Oncology clinical practice guideline: Update on adjuvant endocrine therapy for women with hormone receptor-positive breast cancer
    • Burstein HJ, Prestrud AA, Seidenfeld J, et al. American Society of Clinical Oncology clinical practice guideline: update on adjuvant endocrine therapy for women with hormone receptor-positive breast cancer. J Clin Oncol. 2010;28:3784-96.
    • (2010) J Clin Oncol. , vol.28 , pp. 3784-3796
    • Burstein, H.J.1    Prestrud, A.A.2    Seidenfeld, J.3
  • 33
    • 83355166958 scopus 로고    scopus 로고
    • Older women with breast cancer: Slow progress, great opportunity, now is the time
    • Muss HB, Busby-Whitehead J. Older women with breast cancer: slow progress, great opportunity, now is the time. J Clin Oncol. 2011;29:4608-10.
    • (2011) J Clin Oncol. , vol.29 , pp. 4608-4610
    • Muss, H.B.1    Busby-Whitehead, J.2
  • 34
    • 77957936884 scopus 로고    scopus 로고
    • Early discontinuation and nonadherence to adjuvant hormonal therapy in a cohort of 8,769 early-stage breast cancer patients
    • Hershman DL, Kushi LH, Shao T, et al. Early discontinuation and nonadherence to adjuvant hormonal therapy in a cohort of 8,769 early-stage breast cancer patients. J Clin Oncol. 2010;28:4120-8.
    • (2010) J Clin Oncol. , vol.28 , pp. 4120-4128
    • Hershman, D.L.1    Kushi, L.H.2    Shao, T.3
  • 35
    • 45549095232 scopus 로고    scopus 로고
    • Adherence to oral endocrine therapy for breast cancer: A nursing perspective
    • Miaskowski C, Shockney L, Chlebowski RT. Adherence to oral endocrine therapy for breast cancer: a nursing perspective. Clin J Oncol Nurs. 2008;12:213-21.
    • (2008) Clin J Oncol Nurs. , vol.12 , pp. 213-221
    • Miaskowski, C.1    Shockney, L.2    Chlebowski, R.T.3
  • 36
    • 84856636292 scopus 로고    scopus 로고
    • Comparisons between different polychemotherapy regimens for early breast cancer: Meta-analyses of long-term outcome among 100 000 women in 123 randomised trials
    • Early Breast Cancer Trialists' Collaborative Group (EBCTCG)
    • Early Breast Cancer Trialists' Collaborative Group (EBCTCG), Peto R, Davies C, et al. Comparisons between different polychemotherapy regimens for early breast cancer: meta-analyses of long-term outcome among 100 000 women in 123 randomised trials. Lancet. 2012;379:432-44.
    • (2012) Lancet , vol.379 , pp. 432-444
    • Peto, R.1    Davies, C.2
  • 37
    • 62449193617 scopus 로고    scopus 로고
    • Docetaxel with cyclophosphamide is associated with an overall survival benefit compared with doxorubicin and cyclophosphamide: 7-year follow-up of US Oncology research trial 9735
    • Jones S, Holmes FA, O'Shaughnessy J, et al. Docetaxel with cyclophosphamide is associated with an overall survival benefit compared with doxorubicin and cyclophosphamide: 7-year follow-up of US Oncology research trial 9735. J Clin Oncol. 2009; 27:1177-83.
    • (2009) J Clin Oncol. , vol.27 , pp. 1177-1183
    • Jones, S.1    Holmes, F.A.2    O'Shaughnessy, J.3
  • 38
    • 80053253110 scopus 로고    scopus 로고
    • Adjuvant docetaxel/cyclophosphamide in breast cancer patients over the age of 70: Results of an observational study
    • Freyer G, Campone M, Peron J, et al. Adjuvant docetaxel/cyclophosphamide in breast cancer patients over the age of 70: results of an observational study. Crit Rev Oncol Hematol. 2011;80:466-73.
    • (2011) Crit Rev Oncol Hematol. , vol.80 , pp. 466-473
    • Freyer, G.1    Campone, M.2    Peron, J.3
  • 39
    • 20044388527 scopus 로고    scopus 로고
    • Adjuvant chemotherapy in older and younger women with lymph node-positive breast cancer
    • Muss HB, Woolf S, Berry D, et al. Adjuvant chemotherapy in older and younger women with lymph node-positive breast cancer. JAMA. 2005;293:1073-81.
    • (2005) JAMA. , vol.293 , pp. 1073-1081
    • Muss, H.B.1    Woolf, S.2    Berry, D.3
  • 40
    • 65649108950 scopus 로고    scopus 로고
    • Adjuvant chemotherapy in older women with early-stage breast cancer
    • Muss HB, Berry DA, Cirrincione CT, et al. Adjuvant chemotherapy in older women with early-stage breast cancer. N Engl J Med 2009;360:2055-65.
    • (2009) N Engl J Med , vol.360 , pp. 2055-2065
    • Muss, H.B.1    Berry, D.A.2    Cirrincione, C.T.3
  • 41
    • 58149339881 scopus 로고    scopus 로고
    • Impact of chemotherapy dose intensity on cancer patient outcomes
    • Lyman GH. Impact of chemotherapy dose intensity on cancer patient outcomes. J Natl Compr Canc Netw. 2009;7:99-108.
    • (2009) J Natl Compr Canc Netw. , vol.7 , pp. 99-108
    • Lyman, G.H.1
  • 42
    • 82455168000 scopus 로고    scopus 로고
    • Effect of primary prophylactic G-CSF use on systemic therapy administration for elderly breast cancer patients
    • Rajan S, Stearns S, Lyman G, Carpenter W. Effect of primary prophylactic G-CSF use on systemic therapy administration for elderly breast cancer patients. Breast Cancer Res Treat. 2011;130:255-66.
    • (2011) Breast Cancer Res Treat. , vol.130 , pp. 255-266
    • Rajan, S.1    Stearns, S.2    Lyman, G.3    Carpenter, W.4
  • 43
    • 84862986506 scopus 로고    scopus 로고
    • Appropriate chemotherapy dosing for obese adult patients with cancer: American Society of Clinical Oncology clinical practice guideline
    • Griggs JJ, Mangu PB, Anderson H, et al. Appropriate chemotherapy dosing for obese adult patients with cancer: American Society of Clinical Oncology clinical practice guideline. J Clin Oncol. 2012;30:1553-61.
    • (2012) J Clin Oncol. , vol.30 , pp. 1553-1561
    • Griggs, J.J.1    Mangu, P.B.2    Anderson, H.3
  • 44
    • 80053539103 scopus 로고    scopus 로고
    • Adjuvant trastuzumab in HER2-positive breast cancer
    • Slamon D, Eiermann W, Robert N, et al. Adjuvant trastuzumab in HER2-positive breast cancer. N Engl J Med. 2011;365:1273-83.
    • (2011) N Engl J Med. , vol.365 , pp. 1273-1283
    • Slamon, D.1    Eiermann, W.2    Robert, N.3
  • 45
    • 79956346875 scopus 로고    scopus 로고
    • Chemotherapy options in elderly and frail patients with metastatic colorectal cancer (MRS FOCUS2): An open-label, randomised factorial trial
    • Seymour MT, Thompson LC, Wasan HS, et al. Chemotherapy options in elderly and frail patients with metastatic colorectal cancer (MRS FOCUS2): an open-label, randomised factorial trial. Lancet. 2011;377:1749-59.
    • (2011) Lancet , vol.377 , pp. 1749-1759
    • Seymour, M.T.1    Thompson, L.C.2    Wasan, H.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.