High prevalence of azithromycin-resistant neisseria gonorrhoeae isolates with a multidrug resistance phenotype in Fukuoka, Japan

Sexually Transmitted Diseases

Volumn 42, Issue 6, 2015, Pages 337-341

  Tanaka, Masatoshi ^a   Furuya, Ryusaburo ^a   Irie, Shinichiro ^a   Kanayama, Akiko ^b   Kobayashi, Intetsu ^b  

^a FUKUOKA UNIVERSITY   (Japan)

^b TOHO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AZITHROMYCIN; CEFIXIME; CEFTRIAXONE; CIPROFLOXACIN; PENICILLIN DERIVATIVE; TETRACYCLINE; ANTIINFECTIVE AGENT; BACTERIAL DNA;

ALLELE; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIUM ISOLATE; GENE SEQUENCE; JAPAN; MINIMUM INHIBITORY CONCENTRATION; MULTIANTIGEN SEQUENCE TYPING; MULTIDRUG RESISTANCE; NEISSERIA GONORRHOEAE; NONHUMAN; PHENOTYPE; POR GENE; PREVALENCE; SEQUENCE ANALYSIS; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; TBPB GENE; DNA SEQUENCE; DRUG EFFECTS; FEMALE; GENETICS; GONORRHEA; HUMAN; MALE; MICROBIAL SENSITIVITY TEST; MOLECULAR TYPING; PHYSIOLOGY;

ANTI-BACTERIAL AGENTS; DNA, BACTERIAL; DRUG RESISTANCE, MULTIPLE, BACTERIAL; FEMALE; GONORRHEA; HUMANS; JAPAN; MALE; MICROBIAL SENSITIVITY TESTS; MOLECULAR TYPING; NEISSERIA GONORRHOEAE; PHENOTYPE; PREVALENCE; SEQUENCE ANALYSIS, DNA;

EID: 84929904802     PISSN: 01485717     EISSN: 15374521     Source Type: Journal    
DOI: 10.1097/OLQ.0000000000000279     Document Type: Article

References (25)

1. Lewis DA. Global resistance of Neisseria gonorrhoeae: When theory becomes reality. Curr Opin Infect Dis 2014; 27:62-67.
2. Centers for Disease Control and Prevention. Update to CDC's sexually transmitted diseases treatment guidelines, 2010: Oral cephalosporins no longer a recommended treatment for gonococcal infections. Morb Mortal Wkly Rep 2012; 61:590-594.
3. Bignell C, UnemoM, European STI Guidelines Editorial Board. 2012 European guideline on the diagnosis and treatment of gonorrhoea in adults. Int J STD AIDS 2013; 24:85-92.
4. Japanese Society of Sexually Transmitted Infections. The guideline of the diagnosis and treatment for gonococcal infections [in Japanese]. Jpn J STI 2011; 22:52-59.
5. Takayama Y, Nakayama S, Shimuta K, et al. Characterization of azithromycin-resistant Neisseria gonorrhoeae isolated in Tokyo in 2005-2011. J Infect Chemother 2014; 20:339-341.
6. Starnino S, Stefanelli P, Neisseria gonorrhoeae Italian Study Group. Azithromycin-resistant Neisseria gonorrhoeae strains recently isolated in Italy. J Antimicrob Chemother 2009; 63:1200-1204.
7. Allen VG, Seah C, Martin I, et al. Azithromycin resistance is coevolving with reduced susceptibility to cephalosporins in Neisseria gonorrhoeae in Ontario, Canada. Antimicrob Agents Chemother 2014; 58:2528-2534.
8. UnemoM, Golparian D, Hellmark B. First three Neisseria gonorrhoeae isolates with high-level resistance to azithromycin in Sweden: A threat to currently available dual-antimicrobial regimens for treatment of gonorrhea? Antimicrob Agents Chemother 2014; 58:624-625.
9. Clinical and Laboratory Standards Institute. Performance Standards for Antimicrobial Susceptibility Testing; 22nd Informational Supplement. CLSI Document M100-S22.Wayne, PA: Clinical and Laboratory Standards Institute; 2012.
10. The European Committee on Antimicrobial Susceptibility Testing (EUCAST) Breakpoints tables for interpretation of MICs and zone diameters, Version 4.0, 2014. Available at: http://www.eucast.org/. Accessed February 10, 2015
11. Tapsall JW, Ndowa F, Lewis DA, et al. Meeting the public health challenge of multidrug and extensively drug-resistant Neisseria gonorrhoeae. Expert Rev Anti Infect Ther 2009; 7:821-834.
12. Martin IM, Ison CA, Aanensen DM, et al. Rapid sequence-based identification of gonococcal transmission clusters in a large metropolitan area. J Infect Dis 2004; 189:1497-1505.
13. European Centre for Disease Prevention and Control. Molecular typing of Neisseria gonorrhoeae. Results from a pilot study 2010-2011. 2012. Available at: http://www.ecdc.europa.eu/en/publications/Publications/ 2012 11109-Molecular-typing-gonorrhea.pdf.
14. Tamura K, Peterson D, Peterson N, et al. MEGA5: Molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Mol Biol Evol 2011; 28:2731-2739.
15. Morita-Ishihara T, Unemo M, Furubayashi K, et al. Treatment failure with 2 g of azithromycin (extended-release formulation) in gonorrhoea in Japan caused by the international multidrug-resistant ST1407 strain of Neisseria gonorrhoeae. J Antimicrob Chemother 2014; 69: 2086-2090.
16. Yasuda M, Ito S, Kido A, et al. A single 2 g oral dose of extendedrelease azithromycin for treatment of gonococcal urethritis. J Antimicrob Chemother 2014; 69:3116-3118.
17. Unemo M, Golparian D, Potočnik M, Jeverica S. Treatment failure of pharyngeal gonorrhoea with internationally recommended first-line ceftriaxone verified in Slovenia, September 2011. Euro Surveill 2012; 17:pii: 20200.
18. Unemo M, Golparian D, Hestner A. Ceftriaxone treatment failure of pharyngeal gonorrhoea verified by international recommendations, Sweden, July 2010. Euro Surveill 2011; 16:pii: 19792.
19. Hottes TS, Lester RT, Hoang LM, et al. Cephalosporin and azithromycin susceptibility in Neisseria gonorrhoeae isolates by site of infection, British Columbia, 2006 to 2011. Sex Transm Dis 2013; 40: 46-51.
20. Carannante A, Renna G, Dal Conte I, et al. Changing antimicrobial resistance profiles among Neisseria gonorrhoeae isolates in Italy, 2003 to 2012. Antimicrob Agents Chemother 2014; 58:5871-5876.
21. Mlynarczyk-Bonikowska B, Serwin AB, Golparian D, et al. Antimicrobial susceptibility/resistance and genetic characteristics of Neisseria gonorrhoeae isolates from Poland, 2010-2012. BMC Infect Dis 2014; 14:65.
22. Endimiani A, Guilarte YN, Tinguely R, et al. Characterization of Neisseria gonorrhoeae isolates detected in Switzerland (1998-2012): Emergence of multidrug-resistant clones less susceptible to cephalosporins. BMC Infect Dis 2014; 14:106.
23. Brunner A, Nemes-Nikodem E, Mihalik N, et al. Incidence and antimicrobial susceptibility of Neisseria gonorrhoeae isolates from patients attending the national Neisseria gonorrhoeae reference laboratory of Hungary. BMC Infect Dis 2014; 14:433.
24. Tanaka M, Koga Y, Nakayama H, et al. Antibiotic-resistant phenotypes and genotypes of Neisseria gonorrhoeae isolates in Japan: identification of strain clusters with multidrug-resistant phenotypes. Sex Transm Dis 2011; 38:871-875.
25. Unemo M, Nicholas RA. Emergence of multidrug-resistant, extensively drug-resistant and untreatable gonorrhea. Future Microbiol 2012; 7: 1401-1422.