New plasmid-mediated aminoglycoside 6′-N-acetyltransferase, AAC(6′)-Ian, and ESBL, TLA-3, from a Serratia marcescens clinical isolate

Journal of Antimicrobial Chemotherapy

Volumn 70, Issue 5, 2014, Pages 1331-1337

  Jin, Wanchun ^a   Wachino, Jun Ichi ^a   Kimura, Kouji ^a   Yamada, Keiko ^a   Arakawa, Yoshichika ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Amikacin resistance; Antibiotic resistance genes; S. marcescens

Indexed keywords

ACETYL COENZYME A; ACYLTRANSFERASE; AMIKACIN; AMINOGLYCOSIDE; AMINOGLYCOSIDE 6' N ACYLTRANSFERASE IAN; APRAMYCIN; BACTERIAL ENZYME; EXTENDED SPECTRUM BETA LACTAMASE; GENTAMICIN; HABEKACIN; ISEPAMICIN; KANAMYCIN; NEOMYCIN; NETILMICIN; PAROMOMYCIN; RIBOSTAMYCIN; SISOMICIN; SPECTINOMYCIN; TLA 3 PROTEIN; TOBRAMYCIN; UNCLASSIFIED DRUG; AMINOGLYCOSIDE N(6')-ACETYLTRANSFERASE; BACTERIAL DNA; BETA LACTAMASE;

ACINETOBACTER BAUMANNII; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM CONJUGATION; BACTERIUM ISOLATE; BACTERIUM TRANSFORMATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME PURIFICATION; ENZYME SPECIFICITY; ESCHERICHIA COLI; GENE OVEREXPRESSION; GENETIC ANALYSIS; GENETIC ORGANIZATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MOLECULAR CLONING; NEXT GENERATION SEQUENCING; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMID; PROTEIN TRANSPORT; PROTEUS MIRABILIS; SEQUENCE ANALYSIS; SERRATIA MARCESCENS; THIN LAYER CHROMATOGRAPHY; TURNOVER NUMBER; ANALYSIS; CHEMISTRY; DNA SEQUENCE; DRUG EFFECTS; ENZYMOLOGY; GENETICS; HIGH THROUGHPUT SEQUENCING; HORIZONTAL GENE TRANSFER; HUMAN; ISOLATION AND PURIFICATION; LIQUID CHROMATOGRAPHY; MICROBIOLOGY; SERRATIA INFECTION;

ACETYLTRANSFERASES; BETA-LACTAMASES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, LIQUID; CHROMATOGRAPHY, THIN LAYER; CONJUGATION, GENETIC; DNA, BACTERIAL; GENE TRANSFER, HORIZONTAL; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; PLASMIDS; SEQUENCE ANALYSIS, DNA; SERRATIA INFECTIONS; SERRATIA MARCESCENS;

EID: 84929715405     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dku537     Document Type: Article

References (24)

1. Leibovici L, Vidal L, Paul M. Aminoglycoside drugs in clinical practice: an evidence-based approach. J Antimicrob Chemother 2009; 63: 246-51.
2. Magnet S, Blanchard JS. Molecular insights into aminoglycoside action and resistance. Chem Rev 2005; 105: 477-98.
3. Wachino J, Arakawa Y. Exogenously acquired 16S rRNA methyltransferases found in aminoglycoside-resistant pathogenic Gram-negative bacteria: an update. Drug Resist Updat 2012; 15: 133-48.
4. Yamane K, Wachino J, Suzuki S et al. 16S rRNA methylaseproducing, gram-negative pathogens, Japan. Emerg Infect Dis 2007; 13: 642-6.
5. Azucena E, Mobashery S. Aminoglycoside-modifying enzymes: mechanisms of catalytic processes and inhibition. Drug Resist Updat 2001; 4: 106-17.
6. ′)-VI. MBio 2014; 5: e01972-14.
7. ′)-Iad among Acinetobacter clinical isolates in Japan. Antimicrob Agents Chemother 2004; 48: 2075-80.
8. ′)-Iae gene cassette encoding a novel aminoglycoside acetyltransferase. Antimicrob Agents Chemother 2005; 49: 3734-42.
9. ′-N-acetyltransferase from multidrug-resistant Pseudomonas aeruginosa clinical isolates. Antimicrob Agents Chemother 2009; 53: 2327-34.
10. ′)-Iaj from a clinical isolate of Pseudomonas aeruginosa. Antimicrob Agents Chemother 2013; 57: 96-100.
11. IMP-1-integron in a multidrug-resistant Pseudomonas aeruginosa. PLoS One 2013; 8: e70557.
12. Andrews JM. Determination of minimum inhibitory concentrations. J Antimicrob Chemother 2001; 48 Suppl 1: 5-16.
13. Doi Y, Arakawa Y. 16S ribosomal RNA methylation: emerging resistance mechanism against aminoglycosides. Clin Infect Dis 2007; 45: 88-94.
14. Wachino J, Shibayama K, Kurokawa H et al. Novel plasmid-mediated 16S rRNA m1A1408 methyltransferase, NpmA, found in a clinically isolated Escherichia coli strain resistant to structurally diverse aminoglycosides. Antimicrob Agents Chemother 2007; 51: 4401-9.
15. Lovering AM, White LO, Reeves DS. Identification of aminoglycosideacetylating enzymes by high-pressure liquid chromatographic determination of their reaction products. Antimicrob Agents Chemother 1984; 26: 10-2.
16. Fournier PE, Vallenet D, Barbe V et al. Comparative genomics of multidrug resistance in Acinetobacter baumannii. PLoS Genet 2006; 2: e7.
17. Kim MJ, Hirono I, Kurokawa K et al. Complete DNA sequence and analysis of the transferable multiple-drug resistance plasmids (R plasmids) from Photobacterium damselae subsp. piscicida isolates collected in Japan and the United States. Antimicrob Agents Chemother 2008; 52: 606-11.
18. Heuer H, Kopmann C, Binh CT et al. Spreading antibiotic resistance through spread manure: characteristics of a novel plasmid type with low %G+C content. Environ Microbiol 2009; 11: 937-49.
19. Alcantar-Curiel D, Tinoco JC, Gayosso C et al. Nosocomial bacteremia and urinary tract infections caused by extended-spectrum β-lactamaseproducing Klebsiella pneumoniae with plasmids carrying both SHV-5 and TLA-1 genes. Clin Infect Dis 2004; 38: 1067-74.
20. Silva J, Aguilar C, Ayala G et al. TLA-1: a new plasmid-mediated extended-spectrum β-lactamase from Escherichia coli. Antimicrob Agents Chemother 2000; 44: 997-1003.
21. TLA-1 with a novel ISCR element, ISCR20. Antimicrob Agents Chemother 2010; 54: 4026-8.
22. Girlich D, Poirel L, Schluter A et al. TLA-2, a novel Ambler class A expanded-spectrum β-lactamase. Antimicrob Agents Chemother 2005; 49: 4767-70.
23. Pitout JD, Nordmann P, Laupland KB et al. Emergence of Enterobacteriaceae producing extended-spectrum β-lactamases (ESBLs) in the community. J Antimicrob Chemother 2005; 56: 52-9.
24. ′-amino group except arbekacin and neomycin. J Antibiot (Tokyo) 1999; 52: 889-94.