Origin in acinetobacter guillouiae and dissemination of the aminoglycoside-modifying enzyme Aph(3′)-VI

mBio

Volumn 5, Issue 5, 2014, Pages

  Yoon, Eun Jeong ^a   Goussard, Sylvie ^a   Touchon, Marie ^a,b   Krizova, Lenka ^c   Cerqueira, Gustavo ^d   Murphy, Cheryl ^d   Lambert, Thierry ^e   Grillot Courvalin, Catherine ^a   Nemec, Alexandr ^c   Courvalin, Patrice ^a  

^a INSTITUT PASTEUR   (France)

^b CNRS   (France)

^c NATIONAL INSTITUTE OF PUBLIC HEALTH   (Czech Republic)

^d BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^e UNIVERSITÉ PARIS SACLAY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; AMINOGLYCOSIDE 3' PHOSPHOTRANSFERASE TYPE VI; GENTAMICIN; KANAMYCIN; PHOSPHOTRANSFERASE; UNCLASSIFIED DRUG; AMINOGLYCOSIDE; ANTIINFECTIVE AGENT; KANAMYCIN KINASE;

ACINETOBACTER; ACINETOBACTER BAUMANNII; ACINETOBACTER GUILLOUIAE; ACINETOBACTER PARVUS; ANTIBIOTIC RESISTANCE; APHA6 GENE; ARTICLE; BACTERIAL CHROMOSOME; BACTERIAL GENOME; BACTERIUM CONJUGATION; GENE EXPRESSION; GENE INSERTION SEQUENCE; GENETIC TRANSCRIPTION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENETIC TREE; PROMOTER REGION; SEQUENCE ANALYSIS; STRUCTURAL GENE; TRANSPOSON; AMINO ACID SEQUENCE; CLUSTER ANALYSIS; DRUG EFFECTS; ENZYMOLOGY; ESCHERICHIA COLI; GENETICS; HORIZONTAL GENE TRANSFER; INTERSPERSED REPEAT; ISOLATION AND PURIFICATION; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; MOLECULAR EVOLUTION; MOLECULAR GENETICS; PHYLOGENY; SEQUENCE HOMOLOGY;

ACINETOBACTER;

ACINETOBACTER; AMINO ACID SEQUENCE; AMINOGLYCOSIDES; ANTI-BACTERIAL AGENTS; BASE SEQUENCE; CLUSTER ANALYSIS; CONJUGATION, GENETIC; DRUG RESISTANCE, BACTERIAL; ENVIRONMENTAL MICROBIOLOGY; ESCHERICHIA COLI; EVOLUTION, MOLECULAR; GENE TRANSFER, HORIZONTAL; INTERSPERSED REPETITIVE SEQUENCES; KANAMYCIN KINASE; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; PHYLOGENY; PROMOTER REGIONS, GENETIC; SEQUENCE HOMOLOGY;

EID: 84908429003     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.01972-14     Document Type: Article

References (36)

1. Dijkshoorn L, Nemec A, Seifert H. 2007. An increasing threat in hospitals: multidrug-resistant Acinetobacter baumannii. Nat. Rev. Microbiol. 5:939-951. http://dx.doi.org/10.1038/nrmicro1789.
2. Turton JF, Shah J, Ozongwu C, Pike R. 2010. Incidence of Acinetobacter species other than A. baumannii among clinical isolates of Acinetobacter: evidence for emerging species. J. Clin. Microbiol. 48:1445-1449. http:// dx.doi.org/10.1128/JCM.02467-09.
3. Goldstein FW, Labigne-Roussel A, Gerbaud G, Carlier C, Collatz E, Courvalin P. 1983. Transferable plasmid-mediated antibiotic resistance in Acinetobacter. Plasmid 10:138 -147. http://dx.doi.org/10.1016/0147- 619X(83)90066-5.
4. Devaud M, Kayser FH, Bächi B. 1982. Transposon-mediated multiple antibiotic resistance in Acinetobacter strains. Antimicrob. Agents Chemother. 22:323-329. http://dx.doi.org/10.1128/AAC.22.2.323.
5. Fournier PE, Vallenet D, Barbe V, Audic S, Ogata H, Poirel L, Richet H, Robert C, Mangenot S, Abergel C, Nordmann P, Weissenbach J, Raoult D, Claverie JM. 2006. Comparative genomics of multidrug resistance in Acinetobacter baumannii. PLoS Genet. 2:e7. http://dx.doi.org/ 10.1371/journal.pgen.0020007.
6. Adams MD, Chan ER, Molyneaux ND, Bonomo RA. 2010. Genomewide analysis of divergence of antibiotic resistance determinants in closely related isolates of Acinetobacter baumannii. Antimicrob. Agents Chemother. 54:3569-3577. http://dx.doi.org/10.1128/AAC.00057-10.
7. Magnet S, Courvalin P, Lambert T. 2001. Resistance-nodulation-cell division-type efflux pump involved in aminoglycoside resistance in Acinetobacter baumannii strain BM4454. Antimicrob. Agents Chemother. 45: 3375-3380. http://dx.doi.org/10.1128/AAC.45.12.3375-3380.2001.
8. Galimand M, Courvalin P, Lambert T. 2003. Plasmid-mediated highlevel resistance to aminoglycosides in Enterobacteriaceae due to 16S rRNA methylation. Antimicrob. Agents Chemother. 47:2565-2571. http:// dx.doi.org/10.1128/AAC.47.8.2565-2571.2003.
9. Magnet S, Smith TA, Zheng R, Nordmann P, Blanchard JS. 2003. Aminoglycoside resistance resulting from tight drug binding to an altered aminoglycoside acetyltransferase. Antimicrob. Agents Chemother. 47: 1577-1583. http://dx.doi.org/10.1128/AAC.47.5.1577-1583.2003.
10. Lambert T. 2010. Aminoglycosides and gram-negative bacteria, p 2251577-242. In Courvalin P, Leclercq R, Rice LB (ed), Antibiogram. ASM Press, Washington, DC.
11. Nemec A, Dolzani L, Brisse S, van den Broek P, Dijkshoorn L. 2004. Diversity of aminoglycoside-resistance genes and their association with class 1 integrons among 2 strains of pan-European Acinetobacter baumannii clones. J. Med. Microbiol. 53:1233-1240. http://dx.doi.org/10.1099/ jmm.0.45716-0.
12. Lambert T, Gerbaud G, Courvalin P. 1988. Transferable amikacin resistance in Acinetobacter spp. due to a new type of 3=-aminoglycoside phosphotransferase. Antimicrob. Agents Chemother. 32:15-19. http:// dx.doi.org/10.1128/AAC.32.1.15.
13. Lambert T, Gerbaud G, Courvalin P. 1994. Characterization of transposon Tn1528, which confers amikacin resistance by synthesis of aminoglycoside 3=-O-phosphotransferase type VI. Antimicrob. Agents Chemother. 38:702-706. http://dx.doi.org/10.1128/AAC.38.4.702.
14. Nigro SJ, Post V, Hall RM. 2011. Aminoglycoside resistance in multiply antibiotic-resistant Acinetobacter baumannii belonging to global clone 2 from Australian hospitals. J. Antimicrob. Chemother. 66:1504 -1509. http://dx.doi.org/10.1093/jac/dkr163.
15. Périchon B, Goussard S, Walewski V, Krizova L, Cerqueira G, Murphy C, Feldgarden M, Wortman J, Clermont D, Nemec A, Courvalin P. 2014. Identification of 50 class D beta-lactamases and 65 Acinetobacterderived cephalosporinases in Acinetobacter spp. Antimicrob. Agents Chemother. 58:936-949. http://dx.doi.org/10.1128/AAC.01261-13.
16. Dortet L, Nordmann P, Poirel L. 2012. Association of the emerging carbapenemase NDM-1 with a bleomycin resistance protein in Enterobacteriaceae and Acinetobacter baumannii. Antimicrob. Agents Chemother. 56:1693-1697. http://dx.doi.org/10.1128/AAC.05583-11.
17. NDM-1is a chimera likely constructed in Acinetobacter baumannii. Antimicrob. Agents Chemother. 56:2773-2776. http://dx.doi.org/10.1128/AAC.06297-11.
18. Clinical and Laboratory Standards Institute. 2012. Performance standards for antimicrobial susceptibility testing, vol -M100-MS22. Clinical and Laboratory Standards Institute, Wayne, PA.
19. European Committee on Antimicrobial Susceptibility Testing. 2014. Breakpoint tables for interpretation of MICs and zone diameters, version 4.0. http://eucast.org/clinical_breakpoints/. Accessed 18 January 2014.
20. Fong DH, Berghuis AM. 2002. Substrate promiscuity of an aminoglycoside antibiotic resistance enzyme via target mimicry. EMBO J. 21: 2323-2331. http://dx.doi.org/10.1093/emboj/21.10.2323.
21. Rudant E, Courvalin P, Lambert T. 1998. Characterization of IS18, an element capable of activating the silent aac(6')-Ij gene of Acinetobacter sp. 13 strain BM2716 by transposition. Antimicrob. Agents Chemother. 42: 2759-2761.
22. Hamidian M, Hancock DP, Hall RM. 2013. Horizontal transfer of an ISAba125-activated ampC gene between Acinetobacter baumannii strains leading to cephalosporin resistance. J. Antimicrob. Chemother. 68: 244-245. http://dx.doi.org/10.1093/jac/dks345.
23. Courvalin P, Weisblum B, Davies J. 1977. Aminoglycoside-modifying enzyme of an antibiotic-producing bacterium acts as a determinant of antibiotic resistance in Escherichia coli. Proc. Natl. Acad. Sci. U. S. A. 74:999-1003. http://dx.doi.org/10.1073/pnas.74.3.999.
24. Poirel L, Figueiredo S, Cattoir V, Carattoli A, Nordmann P. 2008. Acinetobacter radioresistens as a silent source of carbapenem resistance for Acinetobacter spp. Antimicrob. Agents Chemother. 52:1252-1256. http:// dx.doi.org/10.1128/AAC.01304-07.
25. Humeniuk C, Arlet G, Gautier V, Grimont P, Labia R, Philippon A. 2002. Beta-lactamases of Kluyvera ascorbata, probable progenitors of some plasmid-encoded CTX-M types. Antimicrob. Agents Chemother. 46:3045-3049. http://dx.doi.org/10.1128/AAC.46.9.3045-3049.2002.
26. Poirel L, Rodriguez-Martinez JM, Mammeri H, Liard A, Nordmann P. 2005. Origin of plasmid-mediated quinolone resistance determinant QnrA. Antimicrob. Agents Chemother. 49:3523-3525. http://dx.doi.org/ 10.1128/AAC.49.8.3523-3525.2005.
27. Spanogiannopoulos P, Waglechner N, Koteva K, Wright GD. 2014. A rifamycin inactivating phosphotransferase family shared by environmental and pathogenic bacteria. Proc. Natl. Acad. Sci. U. S. A. 111:7102-7107. http://dx.doi.org/10.1073/pnas.1402358111.
28. Pruitt KD, Tatusova T, Maglott DR. 2007. NCBI reference sequences (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins. Nucleic Acids Res. 35:D61-D65. http://dx.doi.org/ 10.1093/nar/gkl842.
29. Lesho E, Yoon EJ, McGann P, Snesrud E, Kwak Y, Milillo M, Onmus- Leone F, Preston L, St Clair K, Nikolich M, Viscount H, Wortmann G, Zapor M, Grillot-Courvalin C, Courvalin P, Clifford R, Waterman PE. 2013. Emergence of colistin-resistance in extremely drug-resistant Acinetobacter baumannii containing a novel pmrCAB operon during colistin therapy of wound infections. J. Infect. Dis. 208:1142-1151. http:// dx.doi.org/10.1093/infdis/jit293.
30. Coyne S, Guigon G, Courvalin P, Périchon B. 2010. Screening and quantification of the expression of antibiotic resistance genes in Acinetobacter baumannii with a microarray. Antimicrob. Agents Chemother. 54: 333-340. http://dx.doi.org/10.1128/AAC.01037-09.
31. Nemec A, Musílek M, Sedo O, De Baere T, Maixnerová M, van der Reijden TJ, Zdráhal Z, Vaneechoutte M, Dijkshoorn L. 2010. Acinetobacter bereziniae sp. nov. and Acinetobacter guillouiae sp. nov., to accommodate Acinetobacter genomic species 10 and 11, respectively. Int. J. Syst. Evol. Microbiol. 60:896-903. http://dx.doi.org/10.1099/ijs.0.013656-0.
32. Nemec A, Krizova L, Maixnerova M, van der Reijden TJ, Deschaght P, Passet V, Vaneechoutte M, Brisse S, Dijkshoorn L. 2011. Genotypic and phenotypic characterization of the Acinetobacter calcoaceticus- Acinetobacter baumannii complex with the proposal of Acinetobacter pittii sp. nov. (formerly Acinetobacter genomic species 3) and Acinetobacter nosocomialis sp. nov. (formerly Acinetobacter genomic species 13TU). Res. Microbiol. 162:393-404. http://dx.doi.org/10.1016/j.resmic.2011.02.006.
33. Altschul SF, Madden TL, Schäffer AA, Zhang J, Zhang Z, Miller W, Lipman DJ. 1997. Gapped BLAST and psi-blast: a new generation of protein database search programs. Nucleic Acids Res. 25:3389 -3402. http://dx.doi.org/10.1093/nar/25.17.3389.
34. Martin P, Jullien E, Courvalin P. 1988. Nucleotide sequence of Acinetobacter baumannii aphA-6 gene: evolutionary and functional implications of sequence homologies with nucleotide-binding proteins, kinases and other aminoglycoside-modifying enzymes. Mol. Microbiol. 2:615-625. http://dx.doi.org/10.1111/j.1365-2958.1988.tb00070.x.
35. Vila J, Ruiz J, Navia M, Becerril B, Garcia I, Perea S, Lopez-Hernandez I, Alamo I, Ballester F, Planes AM, Martinez-Beltran J, de Anta TJ. 1999. Spread of amikacin resistance in Acinetobacter baumannii strains isolated in Spain due to an epidemic strain. J. Clin. Microbiol. 37:758-761.
36. Hunger M, Schmucker R, Kishan V, Hillen W. 1990. Analysis and nucleotide sequence of an origin of DNA replication in Acinetobacter calcoaceticus and its use for Escherichia coli shuttle plasmids. Gene 87:45-51. http://dx.doi.org/10.1016/0378-1119(90)90494-C.