CD1d-dependent expansion of NKT follicular helper cells in vivo and in vitro is a product of cellular proliferation and differentiation

International Immunology

Volumn 27, Issue 5, 2015, Pages 253-263

  Rampuria, Pragya ^a   Lang, Mark L ^a  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

CD1d; Follicular helper cells; NKT cells

Indexed keywords

CD1D ANTIGEN; CHEMOKINE RECEPTOR CXCR5; INTERLEUKIN 2; PROTEIN BCL 6; ALPHA-GALACTOSYLCERAMIDE; BCL6 PROTEIN, MOUSE; BLR1 PROTEIN, MOUSE; DNA BINDING PROTEIN; GALACTOSYLCERAMIDE; ICOS PROTEIN, MOUSE; INDUCIBLE T CELL COSTIMULATOR; LYMPHOCYTE ANTIGEN RECEPTOR; PDCD1 PROTEIN, MOUSE; PROGRAMMED DEATH 1 RECEPTOR;

ADOPTIVE TRANSFER; ANIMAL CELL; ARTICLE; CELL COUNT; CELL DIFFERENTIATION; CELL DIVISION; CELL EXPANSION; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; HELPER CELL; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NATURAL KILLER T CELL; NKT FOLLICULAR HELPER CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SPLEEN CELL; ANIMAL; C57BL MOUSE; GENETICS; GERMINAL CENTER; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; TRANSPLANTATION;

ADOPTIVE TRANSFER; ANIMALS; ANTIGENS, CD1D; CELL DIFFERENTIATION; CELL PROLIFERATION; DNA-BINDING PROTEINS; FEMALE; GALACTOSYLCERAMIDES; GERMINAL CENTER; IN VITRO TECHNIQUES; INDUCIBLE T-CELL CO-STIMULATOR PROTEIN; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NATURAL KILLER T-CELLS; PROGRAMMED CELL DEATH 1 RECEPTOR; PROTO-ONCOGENE PROTEINS C-BCL-6; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; RECEPTORS, CXCR5;

EID: 84929666197     PISSN: 09538178     EISSN: 14602377     Source Type: Journal    
DOI: 10.1093/intimm/dxv007     Document Type: Article

References (29)

1. Crotty, S. 2011. Follicular helper CD4 T cells (TFH). Annu. Rev. Immunol. 29:621.
2. McHeyzer-Williams, L. J. and McHeyzer-Williams, M. G. 2005. Antigen-specific memory B cell development. Annu. Rev. Immunol. 23:487.
3. Spolski, R. and Leonard, W. J. 2010. IL-21 and T follicular helper cells. Int. Immunol. 22:7.
4. Chang, P. P., Barral, P., Fitch, J. et al. 2012. Identification of Bcl-6-dependent follicular helper NKT cells that provide cognate help for B cell responses. Nat. Immunol. 13:35.
5. King, I. L., Fortier, A., Tighe, M. et al. 2012. Invariant natural killer T cells direct B cell responses to cognate lipid antigen in an IL-21-dependent manner. Nat. Immunol. 13:44.
6. Tonti, E., Fedeli, M., Napolitano, A. et al. 2012. Follicular helper NKT cells induce limited B cell responses and germinal center formation in the absence of CD4(+) T cell help. J. Immunol. 188:3217.
7. Taniguchi, M., Seino, K. and Nakayama, T. 2003. The NKT cell system:bridging innate and acquired immunity. Nat. Immunol. 4:1164.
8. Kronenberg, M. 2005. Toward an understanding of NKT cell biology:progress and paradoxes. Annu. Rev. Immunol. 23:877.
9. Brigl, M., Tatituri, R. V., Watts, G. F. et al. 2011. Innate and cytokine-driven signals, rather than microbial antigens, dominate in natural killer T cell activation during microbial infection. J. Exp. Med. 208:1163.
10. Rhost, S., Sedimbi, S., Kadri, N. and Cardell, S. L. 2012. Immunomodulatory type II natural killer T lymphocytes in health and disease. Scand. J. Immunol. 76:246.
11. Jahng, A., Maricic, I., Aguilera, C., Cardell, S., Halder, R. C. and Kumar, V. 2004. Prevention of autoimmunity by targeting a distinct, noninvariant CD1d-reactive T cell population reactive to sulfatide. J. Exp. Med. 199:947.
12. Shah, H. B., Devera, T. S., Rampuria, P., Lang, G. A. and Lang, M. L. 2012. Type II NKT cells facilitate Alum-sensing and humoral immunity. J. Leukoc. Biol. 92:883.
13. Zhao, J., Weng, X., Bagchi, S. and Wang, C. R. 2014. Polyclonal type II natural killer T cells require PLZF and SAP for their development and contribute to CpG-mediated antitumor response. Proc. Natl Acad. Sci. USA 111:2674.
14. Galli, G., Pittoni, P., Tonti, E. et al. 2007. Invariant NKT cells sustain specific B cell responses and memory. Proc. Natl Acad. Sci. USA 104:3984.
15. Lang, G. A., Exley, M. A. and Lang, M. L. 2006. The CD1d-binding glycolipid alpha-galactosylceramide enhances humoral immunity to T-dependent and T-independent antigen in a CD1d-dependent manner. Immunology 119:116
16. Devera, T. S., Shah, H. B., Lang, G. A. and Lang, M. L. 2008. Glycolipid-activated NKT cells support the induction of persistent plasma cell responses and antibody titers. Eur. J. Immunol. 38:1001.
17. Devera, T. S., Aye, L. M., Lang, G. A., Joshi, S. K., Ballard, J. D. and Lang, M. L. 2010. CD1d-dependent B-cell help by NK-like T cells leads to enhanced and sustained production of Bacillus anthracis lethal toxin-neutralizing antibodies. Infect. Immun. 78:1610.
18. Devera, T. S., Joshi, S. K., Aye, L. M., Lang, G. A., Ballard, J. D. and Lang, M. L. 2011. Regulation of anthrax toxin-specific antibody titers by natural killer T cell-derived IL-4 and IFNγ. PLoS One 6:e23817.
19. Ko, S. Y., Ko, H. J., Chang, W. S., Park, S. H., Kweon, M. N. and Kang, C. Y. 2005. alpha-Galactosylceramide can act as a nasal vaccine adjuvant inducing protective immune responses against viral infection and tumor. J. Immunol. 175:3309.
20. Bai, L., Deng, S., Reboulet, R. et al. 2013. Natural killer T (NKT)-B-cell interactions promote prolonged antibody responses and long-term memory to pneumococcal capsular polysaccharides. Proc. Natl Acad. Sci. USA 110:16097.
21. Uldrich, A. P., Crowe, N. Y., Kyparissoudis, K. et al. 2005. NKT cell stimulation with glycolipid antigen in vivo: costimulation-dependent expansion, Bim-dependent contraction, and hyporesponsiveness to further antigenic challenge. J. Immunol. 175:3092.
22. Parekh, V. V., Wilson, M. T., Olivares-Villagómez, D. et al. 2005. Glycolipid antigen induces long-term natural killer T cell anergy in mice. J. Clin. Invest. 115:2572.
23. Ballesteros-Tato, A., León, B., Graf, B. A. et al. 2012. Interleukin-2 inhibits germinal center formation by limiting T follicular helper cell differentiation. Immunity 36:847.
24. Exley, M. A., Bigley, N. J., Cheng, O. et al. 2003. Innate immune response to encephalomyocarditis virus infection mediated by CD1d. Immunology 110:519.
25. Lang, G. A., Johnson, A. M., Devera, T. S., Joshi, S. K. and Lang, M. L. 2011. Reduction of CD1d expression in vivo minimally affects NKT-enhanced antibody production but boosts B-cell memory. Int. Immunol. 23:251.
26. Godfrey, D. I., Stankovic, S. and Baxter, A. G. 2010. Raising the NKT cell family. Nat. Immunol. 11:197.
27. Taniguchi, M., Harada, M., Kojo, S., Nakayama, T. and Wakao, H. 2003. The regulatory role of Valpha14 NKT cells in innate and acquired immune response. Annu. Rev. Immunol. 21:483.
28. Venkataswamy, M. M. and Porcelli, S. A. 2010. Lipid and glycolipid antigens of CD1d-restricted natural killer T cells. Semin. Immunol. 22:68.
29. Lee, Y. J., Holzapfel, K. L., Zhu, J., Jameson, S. C. and Hogquist, K. A. 2013. Steady-state production of IL-4 modulates immunity in mouse strains and is determined by lineage diversity of iNKT cells. Nat. Immunol. 14:1146.