Genome-wide RNAi ionomics screen reveals new genes and regulation of human trace element metabolism

Nature Communications

Volumn 5, Issue , 2014, Pages

  Malinouski, Mikalai ^a,b   Hasan, Nesrin M ^c   Zhang, Yan ^a,d   Seravalli, Javier ^b   Lin, Jie ^d   Avanesov, Andrei ^a   Lutsenko, Svetlana ^c   Gladyshev, Vadim N ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b UNIVERSITY OF NEBRASKA LINCOLN   (United States)

^c JOHNS HOPKINS UNIVERSITY   (United States)

^d UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

[No Author keywords available]

Indexed keywords

HEME; IRON; PROTEIN S6; RIBOSOME PROTEIN; SELENIUM; SELENOCYSTEINE; SELENOPROTEIN; SMALL INTERFERING RNA; TRACE ELEMENT; ZINC; ADENOSINE TRIPHOSPHATASE; ATP7A PROTEIN, HUMAN; CATION TRANSPORT PROTEIN;

BIOCHEMISTRY; CELLS AND CELL COMPONENTS; ENZYME ACTIVITY; GENE EXPRESSION; GENOME; ION; LIPID; METABOLISM; NUTRITIONAL STATUS; PROTEIN; RNA; TRACE ELEMENT;

ARTICLE; BIOCHEMICAL ANALYSIS; CELL ASSAY; CONTROLLED STUDY; COPPER METABOLISM; FEMALE; GENE IDENTIFICATION; GENE SILENCING; HIGH THROUGHPUT SCREENING; HOMEOSTASIS; HUMAN; HUMAN CELL; LIPID METABOLISM; MAMMAL CELL; METABOLIC REGULATION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PROCESSING; PROTEIN TRANSPORT; REGULATORY MECHANISM; RNA INTERFERENCE; ZINC METABOLISM; GENE EXPRESSION REGULATION; HEK293 CELL LINE; MASS SPECTROMETRY; METABOLISM; TUMOR CELL LINE;

ADENOSINE TRIPHOSPHATASES; CATION TRANSPORT PROTEINS; CELL LINE, TUMOR; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; MASS SPECTROMETRY; RNA, SMALL INTERFERING; SELENIUM; TRACE ELEMENTS;

EID: 84929659249     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms4301     Document Type: Article

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