Regular exercise decreases liver tumors development in hepatocyte-specific PTEN-deficient mice independently of steatosis

Journal of Hepatology

Volumn 62, Issue 6, 2015, Pages 1296-1303

  Piguet, Anne Christine ^a   Saran, Uttara ^a   Simillion, Cedric ^a   Keller, Irene ^a   Terracciano, Luigi ^b   Reeves, Helen L ^c,d   Dufour, Jean François ^a,e  

^a UNIVERSITY OF BERN   (Switzerland)

^b UNIVERSITY HOSPITAL BASEL   (Switzerland)

^c NEWCASTLE UNIVERSITY   (United Kingdom)

^d NEWCASTLE UNIVERSITY   (United Kingdom)

^e UNIVERSITY OF BERN   (Switzerland)

Author keywords

AMPK; Hepatocellular carcinoma; mTOR; Non alcoholic fatty liver disease; Non alcoholic steatohepatitis

Indexed keywords

ADENYLATE KINASE; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MTOR PROTEIN, MOUSE; PTEN PROTEIN, MOUSE; TARGET OF RAPAMYCIN KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER SIZE; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE; LIPID DIET; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; LIVER INJURY; LIVER NODULE; MALE; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; PRIORITY JOURNAL; TREADMILL EXERCISE; TUMOR CELL; ANIMAL; BODY WEIGHT; DEFICIENCY; GENETICS; HUMAN; KNOCKOUT MOUSE; LIVER; LIVER CELL; LIVER NEOPLASMS, EXPERIMENTAL; METABOLISM; NON-ALCOHOLIC FATTY LIVER DISEASE; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; BODY WEIGHT; GLUCOSE; HEPATOCYTES; HUMANS; LIVER; LIVER NEOPLASMS, EXPERIMENTAL; MALE; MICE; MICE, KNOCKOUT; NON-ALCOHOLIC FATTY LIVER DISEASE; PHYSICAL CONDITIONING, ANIMAL; PTEN PHOSPHOHYDROLASE; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84929606030     PISSN: 01688278     EISSN: 16000641     Source Type: Journal    
DOI: 10.1016/j.jhep.2015.01.017     Document Type: Article

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