-
1
-
-
84869204689
-
Hedgehog signaling blockade delays hepatocarcinogenesis induced by hepatitis B virus X protein
-
Arzumanyan, A., Sambandam, V., Clayton, M. M., Choi, S. S., Xie, G., Diehl, A. M., et al. (2012). Hedgehog signaling blockade delays hepatocarcinogenesis induced by hepatitis B virus X protein. Cancer Res. 72, 5912-5920. doi: 10.1158/0008-5472.CAN-12-2329
-
(2012)
Cancer Res
, vol.72
, pp. 5912-5920
-
-
Arzumanyan, A.1
Sambandam, V.2
Clayton, M.M.3
Choi, S.S.4
Xie, G.5
Diehl, A.M.6
-
2
-
-
80053144962
-
A decade of exploring the cancer epigenome-biological and translational implications
-
Baylin, S. B., and Jones, P. A. (2011). A decade of exploring the cancer epigenome-biological and translational implications. Nat. Rev. Cancer 11, 726-734. doi: 10.1038/nrc3130
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 726-734
-
-
Baylin, S.B.1
Jones, P.A.2
-
3
-
-
61649100307
-
The FGF family: biology, pathophysiology and therapy
-
Beenken, A., and Mohammadi, M. (2009). The FGF family: biology, pathophysiology and therapy. Nat. Rev. Drug Discov. 8, 235-253. doi: 10.1038/nrd2792
-
(2009)
Nat. Rev. Drug Discov
, vol.8
, pp. 235-253
-
-
Beenken, A.1
Mohammadi, M.2
-
4
-
-
14644392179
-
Maintenance of gene expression patterns
-
Brock, H. W., and Fisher, C. L. (2005). Maintenance of gene expression patterns. Dev. Dyn. 232, 633-655. doi: 10.1002/dvdy.20298
-
(2005)
Dev. Dyn
, vol.232
, pp. 633-655
-
-
Brock, H.W.1
Fisher, C.L.2
-
5
-
-
84880449591
-
Lessons learned from lung cancer genomics: the emerging concept of individualized diagnostics and treatment
-
Buettner, R., Wolf, J., and Thomas, R. K. (2013). Lessons learned from lung cancer genomics: the emerging concept of individualized diagnostics and treatment. J. Clin. Oncol. 31, 1858-1865. doi: 10.1200/JCO.2012.45.9867
-
(2013)
J. Clin. Oncol
, vol.31
, pp. 1858-1865
-
-
Buettner, R.1
Wolf, J.2
Thomas, R.K.3
-
6
-
-
0036387193
-
Forkhead transcription factors: key players in development and metabolism
-
Carlsson, P., and Mahlapuu, M. (2002). Forkhead transcription factors: key players in development and metabolism. Dev. Biol. 250, 1-23. doi: 10.1006/dbio.2002.0780
-
(2002)
Dev. Biol
, vol.250
, pp. 1-23
-
-
Carlsson, P.1
Mahlapuu, M.2
-
7
-
-
67449150167
-
A Wnt survival guide: from flies to human disease
-
Chien, A. J., Conrad, W. H., and Moon, R. T. (2009). A Wnt survival guide: from flies to human disease. J. Invest. Dermatol. 129, 1614-1627. doi: 10.1038/jid.2008.445
-
(2009)
J. Invest. Dermatol
, vol.129
, pp. 1614-1627
-
-
Chien, A.J.1
Conrad, W.H.2
Moon, R.T.3
-
8
-
-
40849147041
-
EGFR antagonists in cancer treatment
-
Ciardiello, F., and Tortora, G. (2008). EGFR antagonists in cancer treatment. N. Engl. J. Med. 358, 1160-1174. doi: 10.1056/NEJMra0707704
-
(2008)
N. Engl. J. Med
, vol.358
, pp. 1160-1174
-
-
Ciardiello, F.1
Tortora, G.2
-
9
-
-
33746808398
-
Wnt/β-catenin signaling in development and disease
-
Clevers, H. (2006). Wnt/β-catenin signaling in development and disease. Cell 127, 469-480. doi: 10.1016/j.cell.2006.10.018
-
(2006)
Cell
, vol.127
, pp. 469-480
-
-
Clevers, H.1
-
10
-
-
0021214394
-
Tumorigenesis by mouse mammary tumor virus: proviral activation of a cellular gene in the common integration region int-2
-
Dickson, C., Smith, R., Brookes, S., and Peters, G. (1984). Tumorigenesis by mouse mammary tumor virus: proviral activation of a cellular gene in the common integration region int-2. Cell 37, 529-536. doi: 10.1016/0092-8674(84)90383-0
-
(1984)
Cell
, vol.37
, pp. 529-536
-
-
Dickson, C.1
Smith, R.2
Brookes, S.3
Peters, G.4
-
11
-
-
47949089077
-
VEGF-targeted therapy: mechanisms of anti-tumour activity
-
Ellis, L. M., and Hicklin, D. J. (2008). VEGF-targeted therapy: mechanisms of anti-tumour activity. Nat. Rev. Cancer 8, 579-591. doi: 10.1038/nrc2403
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 579-591
-
-
Ellis, L.M.1
Hicklin, D.J.2
-
12
-
-
18144383021
-
Cellular signaling by fibroblast growth factor receptors
-
Eswarakumar, V. P., Lax, I., and Schlessinger, J. (2005). Cellular signaling by fibroblast growth factor receptors. Cytokine Growth Factor Rev. 16, 139-149. doi: 10.1016/j.cytogfr.2005.01.001
-
(2005)
Cytokine Growth Factor Rev
, vol.16
, pp. 139-149
-
-
Eswarakumar, V.P.1
Lax, I.2
Schlessinger, J.3
-
13
-
-
0345700319
-
A human homolog of Additional sex combs, ADDITIONAL SEX COMBS-LIKE 1, maps to chromosome 20q11
-
Fisher, C. L., Berger, J., Randazzo, F., and Brock, H. W. (2003). A human homolog of Additional sex combs, ADDITIONAL SEX COMBS-LIKE 1, maps to chromosome 20q11. Gene 306, 115-126. doi: 10.1016/S0378-1119(03)00430-X
-
(2003)
Gene
, vol.306
, pp. 115-126
-
-
Fisher, C.L.1
Berger, J.2
Randazzo, F.3
Brock, H.W.4
-
14
-
-
84858600403
-
Mutations in ASXL1 are associated with poor prognosis across the spectrum of malignant myeloid diseases
-
Gelsi-Boyer, V., Brecqueville, M., Devillier, R., Murati, A., Mozziconacci, M. J., and Birnbaum, D. (2012). Mutations in ASXL1 are associated with poor prognosis across the spectrum of malignant myeloid diseases. J. Hematol. Oncol. 5, 12. doi: 10.1186/1756-8722-5-12
-
(2012)
J. Hematol. Oncol
, vol.5
, pp. 12
-
-
Gelsi-Boyer, V.1
Brecqueville, M.2
Devillier, R.3
Murati, A.4
Mozziconacci, M.J.5
Birnbaum, D.6
-
15
-
-
84863938543
-
Wnt pathway inhibition via the targeting of Frizzled receptors results in decreased growth and tumorigenicity of human tumors
-
Gurney, A., Axelrod, F., Bond, C. J., Cain, J., Chartier, C., Donigan, L., et al. (2012). Wnt pathway inhibition via the targeting of Frizzled receptors results in decreased growth and tumorigenicity of human tumors. Proc. Natl. Acad. Sci. U.S.A. 109, 11717-11722. doi: 10.1073/pnas.1120068109
-
(2012)
Proc. Natl. Acad. Sci. U.S.A
, vol.109
, pp. 11717-11722
-
-
Gurney, A.1
Axelrod, F.2
Bond, C.J.3
Cain, J.4
Chartier, C.5
Donigan, L.6
-
16
-
-
62549108593
-
The evolution of Fox genes and their role in development and disease
-
Hannenhalli, S., and Kaestner, K. H. (2009). The evolution of Fox genes and their role in development and disease. Nat. Rev. Genet. 10, 233-240. doi: 10.1038/nrg2523
-
(2009)
Nat. Rev. Genet
, vol.10
, pp. 233-240
-
-
Hannenhalli, S.1
Kaestner, K.H.2
-
17
-
-
0021880669
-
A group of genes controlling the spatial expression of the bithorax complex in Drosophila
-
Jürgens, G. (1985). A group of genes controlling the spatial expression of the bithorax complex in Drosophila. Nature 316, 153-155. doi: 10.1038/316153a0
-
(1985)
Nature
, vol.316
, pp. 153-155
-
-
Jürgens, G.1
-
18
-
-
1842845264
-
Paradigm shift in gene-finding method: from bench-top approach to desk-top approach
-
Katoh, M. (2002a). Paradigm shift in gene-finding method: from bench-top approach to desk-top approach. Int. J. Mol. Med. 10, 677-682
-
(2002)
Int. J. Mol. Med
, vol.10
, pp. 677-682
-
-
Katoh, M.1
-
19
-
-
0242381919
-
WNT and FGF gene clusters
-
Katoh, M. (2002b). WNT and FGF gene clusters. Int. J. Oncol. 21, 1269-1273
-
(2002)
Int. J. Oncol
, vol.21
, pp. 1269-1273
-
-
Katoh, M.1
-
20
-
-
84881108886
-
Functional and cancer genomics of ASXL family members
-
Katoh, M. (2013a). Functional and cancer genomics of ASXL family members. Br. J. Cancer 109, 299-306. doi: 10.1038/bjc.2013.281
-
(2013)
Br. J. Cancer
, vol.109
, pp. 299-306
-
-
Katoh, M.1
-
21
-
-
84883312340
-
Therapeutics targeting angiogenesis: genetics and epigenetics, extracellular miRNAs and signaling networks
-
Katoh, M. (2013b). Therapeutics targeting angiogenesis: genetics and epigenetics, extracellular miRNAs and signaling networks. Int. J. Mol. Med. 32, 763-767. doi: 10.3892/ijmm.2013.1444
-
(2013)
Int. J. Mol. Med
, vol.32
, pp. 763-767
-
-
Katoh, M.1
-
22
-
-
84870376109
-
Cancer genetics and genomics of human FOX family genes
-
Katoh, M., Igarashi, M., Fukuda, H., Nakagama, H., and Katoh, M. (2013). Cancer genetics and genomics of human FOX family genes. Cancer Lett. 328, 198-206. doi: 10.1016/j.canlet.2012.09.017
-
(2013)
Cancer Lett
, vol.328
, pp. 198-206
-
-
Katoh, M.1
Igarashi, M.2
Fukuda, H.3
Nakagama, H.4
Katoh, M.5
-
23
-
-
1542325025
-
Identification and characterization of ASXL2 gene in silico
-
Katoh, M., and Katoh, M. (2003). Identification and characterization of ASXL2 gene in silico. Int. J. Oncol. 23, 845-850
-
(2003)
Int. J. Oncol
, vol.23
, pp. 845-850
-
-
Katoh, M.1
Katoh, M.2
-
24
-
-
16644382513
-
Human FOX gene family
-
Katoh, M., and Katoh, M. (2004a). Human FOX gene family. Int. J. Oncol. 25, 1495-500
-
(2004)
Int. J. Oncol
, vol.25
, pp. 1495-1500
-
-
Katoh, M.1
Katoh, M.2
-
25
-
-
14644397144
-
Identification and characterization of ASXL3 gene in silico
-
Katoh, M., and Katoh, M. (2004b). Identification and characterization of ASXL3 gene in silico. Int. J. Oncol. 24, 1617-1622
-
(2004)
Int. J. Oncol
, vol.24
, pp. 1617-1622
-
-
Katoh, M.1
Katoh, M.2
-
26
-
-
6944226171
-
Identification and characterization of human FOXN5 and rat Foxn5 genes in silico
-
Katoh, M., and Katoh, M. (2004c). Identification and characterization of human FOXN5 and rat Foxn5 genes in silico. Int. J. Oncol. 24, 1339-1344
-
(2004)
Int. J. Oncol
, vol.24
, pp. 1339-1344
-
-
Katoh, M.1
Katoh, M.2
-
27
-
-
34547107319
-
WNT signaling pathway and stem cell signaling network
-
Katoh, M., and Katoh, M. (2007). WNT signaling pathway and stem cell signaling network. Clin. Cancer Res. 13, 4042-4045. doi: 10.1158/1078-0432.CCR-06-2316
-
(2007)
Clin. Cancer Res
, vol.13
, pp. 4042-4045
-
-
Katoh, M.1
Katoh, M.2
-
28
-
-
70350534843
-
Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation
-
Katoh, Y., and Katoh, M. (2009). Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation. Curr. Mol. Med. 9, 873-886. doi: 10.2174/156652409789105570
-
(2009)
Curr. Mol. Med
, vol.9
, pp. 873-886
-
-
Katoh, Y.1
Katoh, M.2
-
29
-
-
84895057195
-
FGF receptors: cancer biology and therapeutics
-
[Epub ahead of print]
-
Katoh, M., and Nakagama, H. (2013). FGF receptors: cancer biology and therapeutics. Med. Res. Rev. doi: 10.1002/med.21288. [Epub ahead of print]
-
(2013)
Med. Res. Rev
-
-
Katoh, M.1
Nakagama, H.2
-
30
-
-
0033584401
-
Molecular cloning of Frizzled-10, a novel member of the Frizzled gene family
-
Koike, J., Takagi, A., Miwa, T., Hirai, M., Terada, M., and Katoh, M. (1999). Molecular cloning of Frizzled-10, a novel member of the Frizzled gene family. Biochem. Biophys. Res. Commun. 262, 39-43. doi: 10.1006/bbrc.1999.1161
-
(1999)
Biochem. Biophys. Res. Commun
, vol.262
, pp. 39-43
-
-
Koike, J.1
Takagi, A.2
Miwa, T.3
Hirai, M.4
Terada, M.5
Katoh, M.6
-
31
-
-
78049425319
-
Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer
-
Kwak, E. L., Bang, Y. J., Camidge, D. R., Shaw, A. T., Solomon, B., Maki, R. G., et al. (2010). Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer. N. Engl. J. Med. 363, 1693-1703. doi: 10.1056/NEJMoa1006448
-
(2010)
N. Engl. J. Med
, vol.363
, pp. 1693-1703
-
-
Kwak, E.L.1
Bang, Y.J.2
Camidge, D.R.3
Shaw, A.T.4
Solomon, B.5
Maki, R.G.6
-
32
-
-
42149181885
-
Structural diversity of G protein-coupled receptors and significance for drug discovery
-
Lagerström, M. C., and Schiöth, H. B. (2008). Structural diversity of G protein-coupled receptors and significance for drug discovery. Nat. Rev. Drug Discov. 7, 339-357. doi: 10.1038/nrd2518
-
(2008)
Nat. Rev. Drug Discov
, vol.7
, pp. 339-357
-
-
Lagerström, M.C.1
Schiöth, H.B.2
-
33
-
-
78650845707
-
G protein-coupled receptors: novel targets for drug discovery in cancer
-
Lappano, R., and Maggiolini, M. (2011). G protein-coupled receptors: novel targets for drug discovery in cancer. Nat. Rev. Drug Discov. 10, 47-60. doi: 10.1038/nrd3320
-
(2011)
Nat. Rev. Drug Discov
, vol.10
, pp. 47-60
-
-
Lappano, R.1
Maggiolini, M.2
-
34
-
-
0037866671
-
Fox's in development and disease
-
Lehmann, O. J., Sowden, J. C., Carlsson, P., Jordan, T., and Bhattacharya, S. S. (2003). Fox's in development and disease. Trends Genet. 19, 339-344. doi: 10.1016/S0168-9525(03)00111-2
-
(2003)
Trends Genet
, vol.19
, pp. 339-344
-
-
Lehmann, O.J.1
Sowden, J.C.2
Carlsson, P.3
Jordan, T.4
Bhattacharya, S.S.5
-
35
-
-
84875937242
-
Genotyping and genomic profiling of non-small-cell lung cancer: implications for current and future therapies
-
Li, T., Kung, H. J., Mack, P. C., and Gandara, D. R. (2013). Genotyping and genomic profiling of non-small-cell lung cancer: implications for current and future therapies. J. Clin. Oncol. 31, 1039-1049. doi: 10.1200/JCO.2012.45.3753
-
(2013)
J. Clin. Oncol
, vol.31
, pp. 1039-1049
-
-
Li, T.1
Kung, H.J.2
Mack, P.C.3
Gandara, D.R.4
-
36
-
-
78751558425
-
Development of RET kinase inhibitors for targeted cancer therapy
-
Mologni, L. (2011). Development of RET kinase inhibitors for targeted cancer therapy. Curr. Med. Chem. 18, 162-175. doi: 10.2174/092986711794088308
-
(2011)
Curr. Med. Chem
, vol.18
, pp. 162-175
-
-
Mologni, L.1
-
37
-
-
0021270667
-
Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15
-
Nusse, R., van Ooyen, A., Cox, D., Fung, Y. K., and Varmus, H. (1984). Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15. Nature 307, 131-136. doi: 10.1038/307131a0
-
(1984)
Nature
, vol.307
, pp. 131-136
-
-
Nusse, R.1
van Ooyen, A.2
Cox, D.3
Fung, Y.K.4
Varmus, H.5
-
38
-
-
77956058729
-
Epigenetics and cardiovascular disease
-
Ordovás, J. M., and Smith, C. E. (2010). Epigenetics and cardiovascular disease. Nat. Rev. Cardiol. 7, 510-519. doi: 10.1038/nrcardio.2010.104
-
(2010)
Nat. Rev. Cardiol
, vol.7
, pp. 510-519
-
-
Ordovás, J.M.1
Smith, C.E.2
-
39
-
-
48549088705
-
Vascular endothelial growth factor in eye disease
-
Penn, J. S., Madan, A., Caldwell, R. B., Bartoli, M., Caldwell, R. W., and Hartnett, M. E. (2008). Vascular endothelial growth factor in eye disease. Prog. Retin. Eye Res. 27, 331-371. doi: 10.1016/j.preteyeres.2008.05.001
-
(2008)
Prog. Retin. Eye Res
, vol.27
, pp. 331-371
-
-
Penn, J.S.1
Madan, A.2
Caldwell, R.B.3
Bartoli, M.4
Caldwell, R.W.5
Hartnett, M.E.6
-
40
-
-
80052420490
-
Hedgehog signaling antagonist promotes regression of both liver fibrosis and hepatocellular carcinoma in a murine model of primary liver cancer
-
Philips, G. M., Chan, I. S., Swiderska, M., Schroder, V. T., Guy, C., Karaca, G. F., et al. (2011). Hedgehog signaling antagonist promotes regression of both liver fibrosis and hepatocellular carcinoma in a murine model of primary liver cancer. PLoS ONE 6:e23943. doi: 10.1371/journal.pone.0023943
-
(2011)
PLoS ONE
, vol.6
-
-
Philips, G.M.1
Chan, I.S.2
Swiderska, M.3
Schroder, V.T.4
Guy, C.5
Karaca, G.F.6
-
41
-
-
0032501156
-
Molecular cloning, differential expression, and chromosomal localization of human Frizzled-1, Frizzled-2, and Frizzled-7
-
Sagara, N., Toda, G., Hirai, M., Terada, M., and Katoh, M. (1998). Molecular cloning, differential expression, and chromosomal localization of human Frizzled-1, Frizzled-2, and Frizzled-7. Biochem. Biophys. Res. Commun. 252, 117-122. doi: 10.1006/bbrc.1998.9607
-
(1998)
Biochem. Biophys. Res. Commun
, vol.252
, pp. 117-122
-
-
Sagara, N.1
Toda, G.2
Hirai, M.3
Terada, M.4
Katoh, M.5
-
42
-
-
84860391821
-
Oncogenic activation of FOXR1 by 11q23 intrachromosomal deletion-fusions in neuroblastoma
-
Santo, E. E., Ebus, M. E., Koster, J., Schulte, J. H., Lakeman, A., van Sluis, P., et al. (2012). Oncogenic activation of FOXR1 by 11q23 intrachromosomal deletion-fusions in neuroblastoma. Oncogene 31, 1571-1581. doi: 10.1038/onc.2011.344
-
(2012)
Oncogene
, vol.31
, pp. 1571-1581
-
-
Santo, E.E.1
Ebus, M.E.2
Koster, J.3
Schulte, J.H.4
Lakeman, A.5
van Sluis, P.6
-
43
-
-
84881159953
-
Structural biology: meet the B family
-
Sexton, P. M., and Wootten, D. (2013). Structural biology: meet the B family. Nature 499, 417-418. doi: 10.1038/nature12413
-
(2013)
Nature
, vol.499
, pp. 417-418
-
-
Sexton, P.M.1
Wootten, D.2
-
44
-
-
0031946630
-
The Additional sex combs gene of Drosophila encodes a chromatin protein that binds to shared and unique Polycomb group sites on polytene chromosomes
-
Sinclair, D. A., Milne, T. A., Hodgson, J. W., Shellard, J., Salinas, C. A., Kyba, M., et al. (1998). The Additional sex combs gene of Drosophila encodes a chromatin protein that binds to shared and unique Polycomb group sites on polytene chromosomes. Development 125, 1207-1216
-
(1998)
Development
, vol.125
, pp. 1207-1216
-
-
Sinclair, D.A.1
Milne, T.A.2
Hodgson, J.W.3
Shellard, J.4
Salinas, C.A.5
Kyba, M.6
-
45
-
-
12344274486
-
The biology of vascular endothelial growth factors
-
Tammela, T., Enholm, B., Alitalo, K., and Paavonen, K. (2005). The biology of vascular endothelial growth factors. Cardiovasc. Res. 65, 550-563. doi: 10.1016/j.cardiores.2004.12.002
-
(2005)
Cardiovasc. Res
, vol.65
, pp. 550-563
-
-
Tammela, T.1
Enholm, B.2
Alitalo, K.3
Paavonen, K.4
-
46
-
-
84867915488
-
Extracellular miRNAs: the mystery of their origin and function
-
Turchinovich, A., Weiz, L., and Burwinkel, B. (2012). Extracellular miRNAs: the mystery of their origin and function. Trends Biochem. Sci. 37, 460-465. doi: 10.1016/j.tibs.2012.08.003
-
(2012)
Trends Biochem. Sci
, vol.37
, pp. 460-465
-
-
Turchinovich, A.1
Weiz, L.2
Burwinkel, B.3
-
47
-
-
78649474756
-
Serum microRNAs as powerful cancer biomarkers
-
Wittmann, J., and Jäck, H. M. (2010). Serum microRNAs as powerful cancer biomarkers. Biochim. Biophys. Acta. 1806, 200-207
-
(2010)
Biochim. Biophys. Acta
, vol.1806
, pp. 200-207
-
-
Wittmann, J.1
Jäck, H.M.2
|