Genome sequence analysis of in vitro and in vivo phenotypes of Bunyamwera and Ngari virus isolates from Northern Kenya

PLoS ONE

Volumn 9, Issue 8, 2014, Pages

  Odhiambo, Collins ^a,b,c   Venter, Marietjie ^b,d   Limbaso, Konongoi ^c   Swanepoel, Robert ^b   Sang, Rosemary ^a,c  

^a INTERNATIONAL CENTRE OF INSECT PHYSIOLOGY AND ECOLOGY ICIPE   (Kenya)

^b UNIVERSITY OF PRETORIA   (South Africa)

^c KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

^d CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARBOVIRUS; ARTICLE; BUNYAMWERA VIRUS; CONTROLLED STUDY; GENE MUTATION; GENE SEQUENCE; GENETIC CONSERVATION; GENETIC VARIABILITY; GROWTH RATE; IN VITRO STUDY; IN VIVO STUDY; KENYA; MOUSE; NEWBORN; NGARI VIRUS; NONHUMAN; PHENOTYPE; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS; VERO CELL LINE; VIRUS ATTENUATION; VIRUS GENOME; VIRUS ISOLATION; VIRUS PATHOGENESIS; VIRUS REPLICATION; ANIMAL; CLASSIFICATION; GENETICS; HUMAN; ISOLATION AND PURIFICATION;

ANIMALS; BUNYAMWERA VIRUS; GENETIC VARIATION; GENOME, VIRAL; HUMANS; KENYA; MICE; PHENOTYPE; SEQUENCE ANALYSIS, RNA;

EID: 84929518169     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0105446     Document Type: Article

References (27)

1. Gonzalez JP, Georges AJ (1988) Bunyaviral fevers: Bunyamwera, Ilesha, Germiston, Bwamba and Tataguine. In: Monath T, editor The Arboviruses: Epidemiology and Ecology. Boca Raton, FL: CRC press.pp. 87-98.
2. Bowen MD, Trappier SG, Sanchez AJ, Meyer RF, Goldsmith CS, et al. (2001) A reassortant bunyavirus isolated from acute hemorrhagic fever cases in Kenya and Somalia. Virol 291: 185-190. (Pubitemid 34095174)
3. Briese T, Bird B, Kapoor V, Nichol ST, Lipkin WI (2006) Batai and Ngari viruses: M segment reassortment and association with severe febrile disease outbreaks in East Africa. J Virol 80: 5627-5630.
4. Gerrard SR, Li L, Barrett AD, Nichol ST (2004) Ngari virus is a Bunyamwera virus reassortant that can be associated with large outbreaks of hemorrhagic fever in Africa. J Virol 78: 8922-8926. (Pubitemid 39025158)
5. Elliot RM, Bouloy M, Calisher CH, Goldbach R, Moyer JT, et al. (2000) Family Bunyaviridae. In. van Regenmortel MHV, Fauquet CM, Bishop DHL, Carsten EB, Estes MK, Lemon SM, Maniloff J, Mayo MA, McGeoch DJ, Pringle CR, Wickner RB, editors. Virus taxonomy: VIIth report of the International Committee on Taxonomy of Viruses.San Diego: Academic press. pp. 599-621.
6. Schmaljohn CS, Hooper JW (2001) Bunyaviridae: The viruses and their replication In: Fields BN, Howley PM, Griffin DE, editors. Bunyaviridae: The viruses and their replication. Philadelphia PA: Fields' virology Lippincott Williams and Wilkins. pp. 1581-1602.
7. Sundstrom KB, Stoltz M, Lagerqvist N, Lundkvist A, Nemirov K, et al. (2011) Characterization of two substrains of Puumala virus that show phenotypes that are different from each other and from the original strain. J Virol 85: 1747-1756.
8. Davis CT, Beasley DW, Guzman H, Siirin M, Parsons RE, et al. (2004) Emergence of attenuated West Nile virus variants in Texas, 2003. Virol 330: 342-350. (Pubitemid 39446591)
9. Blaney JE Jr, Johnson DH, Firestone CY, Hanson CT, Murphy BR, et al. (2001) Chemical Mutagenesis of Dengue Virus Type 4 Yields Mutant Viruses Which Are Temperature Sensitive in Vero Cells or Human Liver Cells and Attenuated in Mice. J Virol 75: 9731-9740. (Pubitemid 32900108)
10. Blaney JE Jr, Johnson DH, Manipon GG, Firestone CY, Hanson CT, et al. (2002) Genetic basis of attenuation of dengue virus type 4 small plaque mutants with restricted replication in suckling mice and in SCID mice transplanted with human liver cells. Virol 300: 125-139.
11. Blaney JE Jr, Manipon GG, Murphy BR, Whitehead SS (2003) Temperature sensitive mutations in the genes encoding the NS1, NS2A, NS3, and NS5 nonstructural proteins of dengue virus type 4 restrict replication in the brains of mice 4. Arch Virol 148: 999-1006. (Pubitemid 36562489)
12. Eastman PS, Blair CD (1985) Temperature-sensitive mutants of Japanese encephalitis virus. J Virol 55: 611-616. (Pubitemid 16249668)
13. Ochieng C, Lutomiah J, Makio A, Koka H, Chepkorir E, et al. (2013) Mosquito-borne arbovirus surveillance at selected sites in diverse ecological zones of Kenya; 2007-2012. Virol J 10: 140.
14. R Development Core Team (2008) R: A language and environment for statistical computing: statistical computing. R Foundation for Statistical Computing. Vienna, Austria. ISBN 3-900051-07-0. Available: http://www.Rproject. org.
15. Jost H, Bialonski A, Schmetz C, Gunther S, Becker N, et al. (2011) Isolation and phylogenetic analysis of Batai virus, Germany. Am J Trop Med Hyg 84: 241-243.
16. Yanase T, Kato T, Yamakawa M, Takayoshi K, Nakamura K, et al. (2006) Genetic characterization of Batai virus indicates a genomic reassortment between orthobunyaviruses in nature. Arch Virol 151: 2253-2260. (Pubitemid 44627760)
17. Altschul SF, Gish W, Miller W, Myers EW, Lipman DJ (1990) Basic local alignment search tool. J Mol Biol 215: 403-410.
18. Tamura K, Peterson D, Peterson N, Stecher G, Nei M, et al. (2011) MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Mol Biol Evol 28: 2731-2739.
19. Kanno T, Inoue T, Mackay D, Kitching P, Yamaguchi S, et al. (1998) Viruses produced from complementary DNA of virulent and avirulent strains of swine vesicular disease viruses retain the in vivo and in vitro characteristics of the parental strain. Arch Virol 143: 1055-1062. (Pubitemid 28324184)
20. Ramsingh AI, Caggana M, Ronstrom S (1995) Genetic mapping of the determinants of plaque morphology of coxsackievirus B4. Arch Virol 140: 2215-2226.
21. Zhang H, Blake NW, Ouyang X, Pandolfino YA, Morgan-Capner P, et al. (1995) A single amino acid substitution in the capsid protein VP1 of coxsackievirus B3 (CVB3) alters plaque phenotype in Vero cells but not cardiovirulence in a mouse model. Arch Virol 140: 959-966.
22. Kanno T, Mackay D, Inoue T, Wilsden G, Yamakawa M, et al. (1999) Mapping the genetic determinants of pathogenicity and plaque phenotype in swine vesicular disease virus. J Virol 73: 2710-2716. (Pubitemid 29135656)
23. Endres MJ, Griot C, Gonzalez-Scarano F, Nathanson N (1991) Neuroattenuation of an avirulent bunyavirus variant maps to the L RNA segment. J Virol 65: 5465-5470.
24. Shi X, Elliott RM (2009) Generation and analysis of recombinant Bunyamwera orthobunyaviruses expressing V5 epitope-tagged L proteins. J Gen Virol 90: 297-306.
25. Kohl A, Lowen AC, Léonard VHJ, Elliott RM (2006) Genetic elements regulating packaging of the Bunyamwera orthobunyavirus genome. J Gen Virol 87: 177-187. (Pubitemid 43056956)
26. Lowen AC, Elliott RM (2005) Mutational analyses of the nonconserved sequences in the Bunyamwera Orthobunyavirus S segment untranslated regions. J Virol 79: 12861-12870. (Pubitemid 41433205)
27. Mazel-Sanchez B, Elliott RM (2012) Attenuation of bunyamwera orthobunya-virus replication by targeted mutagenesis of genomic untranslated regions and creation of viable viruses with minimal genome segments. J Virol 86: 13672-13678.