From loss to loneliness: The relationship between bereavement and depressive symptoms

Journal of Abnormal Psychology

Volumn 124, Issue 2, 2015, Pages 256-265

  Fried, Eiko I ^a   Bockting, Claudi ^b,c   Arjadi, Retha ^b   Borsboom, Denny ^d   Amshoff, Maximilian ^b   Cramer, Angélique O J ^d   Epskamp, Sacha ^d   Tuerlinckx, Francis ^a   Carr, Deborah ^e   Stroebe, Margaret ^b,c  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY OF GRONINGEN   (Netherlands)

^c UTRECHT UNIVERSITY   (Netherlands)

^d UNIVERSITY OF AMSTERDAM   (Netherlands)

^e Camden Campus of Rutgers The State University of New Jersey   (United States)

Author keywords

Bereavement; Depressive symptoms; Latent variable model; Loneliness; Networks

Indexed keywords

AGED; ALGORITHM; ARTICLE; BEREAVEMENT; CENTER FOR EPIDEMIOLOGIC STUDIES DEPRESSION SCALE; CONTROLLED STUDY; DEATH; DEPRESSION; FEMALE; HAPPINESS; HUMAN; LIFE EVENT; LONELINESS; LOSS OF APPETITE; MAJOR CLINICAL STUDY; MALE; MENTAL DISEASE ASSESSMENT; PREDICTION; PROSPECTIVE STUDY; SADNESS; SPOUSE; STATISTICAL MODEL; STATISTICAL PARAMETERS; SYMPTOMATOLOGY; WIDOW; WIDOWER; FOLLOW UP; PSYCHOLOGY; VERY ELDERLY;

AGED; AGED, 80 AND OVER; BEREAVEMENT; DEPRESSION; FEMALE; FOLLOW-UP STUDIES; HUMANS; LONELINESS; MALE;

EID: 84929516553     PISSN: 0021843X     EISSN: 19391846     Source Type: Journal    
DOI: 10.1037/abn0000028     Document Type: Article

References (83)

1. Andreasen, N. (2001). Brave new brain: Conquering mental illness in the era of the genome. New York, NY: Oxford University Press.
2. American Psychiatric Association. (1980). Diagnostic and statistical manual of mental disorders (3rd ed.). Washington, DC: Author.
3. American Psychiatric Association. (2000). Diagnostic and Statistical Manual of Mental Disorders (4th ed., text rev.). Washington, DC: Author.
4. American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Washington, DC: Author.
5. Beck, A. T., Rush, J. A., Shaw, F. S., & Emery, G. (1979). Cognitive therapy of depression. New York, NY: Guilford Press.
6. Beck, A. T., Steer, R. A., & Garbin, M. G. (1988). Psychometric properties of the Beck Depression Inventory: Twenty-five years of evaluation. Clinical Psychology Review, 8, 77-100. http://dx.doi.org/10.1016/0272-7358(88)90050-5
7. Bonanno, G. A., Wortman, C. B., Lehman, D. R., Tweed, R. G., Haring, M., Sonnega, J., . . . Nesse, R. M. (2002). Resilience to loss and chronic grief: A prospective study from preloss to 18-months postloss. Journal of Personality and Social Psychology, 83, 1150-1164. http://dx.doi.org/10.1037/0022-3514.83.5.1150
8. Boomsma, D., Busjahn, A., & Peltonen, L. (2002). Classical twin studies and beyond. Nature Reviews Genetics, 3, 872-882. http://dx.doi.org/10.1038/nrg932
9. Borsboom, D., & Cramer, A. O. J. (2013). Network analysis: An integrative approach to the structure of psychopathology. Annual Review of Clinical Psychology, 9, 91-121. http://dx.doi.org/10.1146/annurevclinpsy-050212-185608
10. Brown, G. W., & Harris, T. O. (1989). Depression. In G. W. Brown & T. O. Harris (Eds.), Life events and illness (pp. 49-93). New York, NY: Guilford Press.
11. Cacioppo, J. T., Hawkley, L. C., & Thisted, R. A. (2010). Perceived social isolation makes me sad: 5-year cross-lagged analyses of loneliness and depressive symptomatology in the Chicago Health, Aging, and Social Relations Study. Psychology and Aging, 25, 453-463. http://dx.doi.org/10.1037/a0017216
12. Carr, D. (2009). Who's to blame? Perceived responsibility for spousal death and psychological distress among older widowed persons. Journal of Health and Social Behavior, 50, 359-375. http://dx.doi.org/10.1177/002214650905000308
13. Carr, D., House, J. S., Kessler, R. C., Nesse, R. M., Sonnega, J., & Wortman, C. (2000). Marital quality and psychological adjustment to widowhood among older adults: A longitudinal analysis. The Journals of Gerontology: Series B: Psychological Sciences and Social Sciences, 55, S197-S207. http://dx.doi.org/10.1093/geronb/55.4.S197
14. Carr, D., House, J. S., Wortman, C., Nesse, R., & Kessler, R. C. (2001). Psychological adjustment to sudden and anticipated spousal loss among older widowed persons. The Journals of Gerontology: Series B: Psychological Sciences and Social Sciences, 56, S237-S248. http://dx.doi .org/10.1093/geronb/56.4.S237
15. Carr, D., Nesse, R. M., & Wortman, C. (2006). Spousal bereavement in late life. New York: Springer.
16. Charles, S., & Carstensen, L. (2013). Emotion regulation and aging. In J. Gross (Ed.), Handbook of emotion regulation (2nd ed., pp. 202-218). New York, NY: Guilford Press.
17. Cramer, A. O. J., Borsboom, D., Aggen, S. H., & Kendler, K. S. (2013). The pathoplasticity of dysphoric episodes: Differential impact of stressful life events on the pattern of depressive symptom inter-correlations. Psychological Medicine, 42, 957-965. http://dx.doi.org/10.1017/S003329171100211X
18. Cramer, A. O. J., Waldorp, L. J., van der Maas, H. L. J., & Borsboom, D. (2010). Comorbidity: A network perspective. Behavioral and Brain Sciences, 33, 137-150. http://dx.doi.org/10.1017/S0140525X09991567
19. Epskamp, S., Cramer, A. O. J., Waldorp, L. J., Schmittmann, V. D., & Borsboom, D. (2012). qgraph: Network visualizations of relationships in psychometric data. Journal of Statistical Software, 48, 1-18.
20. Frewen, P. A., Allen, S. L., Lanius, R. A., & Neufeld, R. W. J. (2012). Perceived causal relations: Novel methodology for assessing client attributions about causal associations between variables including symptoms and functional impairment. Assessment, 19, 480-493. http://dx.doi .org/10.1177/1073191111418297
21. Frewen, P. A., Schmittmann, V. D., Bringmann, L. F., & Borsboom, D. (2013). Perceived causal relations between anxiety, posttraumatic stress and depression: Extension to moderation, mediation, and network analysis. European Journal of Psychotraumatology, 4(20656).
22. Fried, E. I., & Nesse, R. M. (2015). Depression is not a consistent syndrome: An investigation of unique symptom patterns in the STAR_D study. Journal of Affective Disorders, 172, 96-102. http://dx.doi.org/10.1016/j.jad.2014.10.010
23. Fried, E. I., Nesse, R. M., Zivin, K., Guille, C., & Sen, S. (2014). Depression is more than the sum score of its parts: Individual DSM symptoms have different risk factors. Psychological Medicine, 44, 1-10.
24. Friedman, R. A. (2013). Grief, depression, and the DSM-5. The New England Journal of Medicine, 366, 1855-1857. http://dx.doi.org/10.1056/NEJMp1201794
25. Fruchterman, T., & Reingold, E. (1991). Graph drawing by force-directed placement. Software, Practice & Experience, 21, 1129-1164. http://dx.doi.org/10.1002/spe.4380211102
26. Hammen, C. (2005). Stress and depression. Annual Review of Clinical Psychology, 1, 293-319. http://dx.doi.org/10.1146/annurev.clinpsy.1.102803.143938
27. Hawkley, L. C., & Cacioppo, J. T. (2003). Loneliness and pathways to disease. Brain, Behavior, and Immunity, 17(Suppl 1), S98-S105. http://dx.doi.org/10.1016/S0889-1591(02)00073-9
28. Hawkley, L. C., Preacher, K. J., & Cacioppo, J. T. (2010). Loneliness impairs daytime functioning but not sleep duration. Health Psychology, 29, 124-129. http://dx.doi.org/10.1037/a0018646
29. Hek, K., Demirkan, A., Lahti, J., Terracciano, A., Teumer, A., Cornelis, M. C., . . . Murabito, J. (2013). A genome-wide association study of depressive symptoms. Biological Psychiatry, 73, 667-678. http://dx.doi .org/10.1016/j.biopsych.2012.09.033
30. Hu, L., & Bentler, P. M. (1999). Cutoff criteria for fit indexes in covariance structure analysis: Conventional criteria versus new alternatives. Structural Equation Modeling, 6, 1-55. http://dx.doi.org/10.1080/10705519909540118
31. Jang, K. L., Livesley, W. J., Taylor, S., Stein, M. B., & Moon, E. C. (2004). Heritability of individual depressive symptoms. Journal of Affective Disorders, 80, 125-133. http://dx.doi.org/10.1016/S0165-0327(03)00108-3
32. Jaussent, I., Bouyer, J., Ancelin, M.-L., Akbaraly, T., Pérès, K., Ritchie, K., . . . Dauvilliers, Y. (2011). Insomnia and daytime sleepiness are risk factors for depressive symptoms in the elderly. Sleep: Journal of Sleep and Sleep Disorders Research, 34, 1103-1110.
33. Johnson, W., Penke, L., & Spinath, F. (2011). Heritability in the era of molecular genetics: Some thoughts for understanding genetic influences on behavioural traits. European Journal of Personality, 266, 254-266. http://dx.doi.org/10.1002/per
34. Jones, R. N. (2006). Identification of measurement differences between English and Spanish language versions of the Mini-Mental State Examination. Detecting differential item functioning using MIMIC modeling. Medical Care, 44(11, Suppl 3), S124-S133. http://dx.doi.org/10.1097/01.mlr.0000245250.50114.0f
35. Jöreskog, K., & Goldberger, A. (1975). Estimation of a model with multiple indicators and multiple causes of a single latent variable. Journal of the American Statistical Association, 70, 631-639. http://dx .doi.org/10.2307/2285946
36. Keller, M. C., Neale, M. C., & Kendler, K. S. (2007). Association of different adverse life events with distinct patterns of depressive symptoms. The American Journal of Psychiatry, 164, 1521-1529. http://dx .doi.org/10.1176/appi.ajp.2007.06091564
37. Keller, M. C., & Nesse, R. M. (2005). Is low mood an adaptation? Evidence for subtypes with symptoms that match precipitants. Journal of Affective Disorders, 86, 27-35. http://dx.doi.org/10.1016/j.jad.2004.12.005
38. Keller, M. C., & Nesse, R. M. (2006). The evolutionary significance of depressive symptoms: Different adverse situations lead to different depressive symptom patterns. Journal of Personality and Social Psychology, 91, 316-330. http://dx.doi.org/10.1037/0022-3514.91.2.316
39. Kendler, K. S. (2012). The dappled nature of causes of psychiatric illness: Replacing the organic-functional/hardware-software dichotomy with empirically based pluralism. Molecular Psychiatry, 17, 377-388. http://dx.doi.org/10.1038/mp.2011.182
40. Kendler, K. S., Aggen, S. H., & Neale, M. C. (2013). Evidence for multiple genetic factors underlying DSM-IV criteria for major depression. JAMA Psychiatry, 70, 599-607. http://dx.doi.org/10.1001/jamapsychiatry .2013.751
41. Kendler, K. S., Myers, J., & Zisook, S. (2008). Does bereavement-related major depression differ from major depression associated with other stressful life events? The American Journal of Psychiatry, 165, 1449-1455. http://dx.doi.org/10.1176/appi.ajp.2008.07111757
42. Kersting, A., Brähler, E., Glaesmer, H., & Wagner, B. (2011). Prevalence of complicated grief in a representative population-based sample. Journal of Affective Disorders, 131, 339-343. http://dx.doi.org/10.1016/j.jad .2010.11.032
43. Kessler, R. C., Berglund, P., Demler, O., Jin, R., Koretz, D., Merikangas, K. R., . . . Wang, P. S., & the National Comorbidity Survey Replication. (2003). The epidemiology of major depressive disorder: Results from the National Comorbidity Survey Replication (NCS-R). JAMA: Journal of the American Medical Association, 289, 3095-3105. http://dx.doi.org/10.1001/jama.289.23.3095
44. Kessler, R. C., Chiu, W. T., Demler, O., Merikangas, K. R., & Walters, E. E. (2005). Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. Archives of General Psychiatry, 62, 617-627. http://dx.doi.org/10.1001/archpsyc.62.6.617
45. Kim, N. S., & Ahn, W. K. (2002). Clinical psychologists' theory-based representations of mental disorders predict their diagnostic reasoning and memory. Journal of Experimental Psychology: General, 131, 451-476. http://dx.doi.org/10.1037/0096-3445.131.4.451
46. Knight, B., & Silverstein, M. (2014). Editors' preface to the special issue on widowhood and bereavement. The Journals of Gerontology: Series B: Psychological Sciences and Social Sciences, 69B(1), 1. http://dx.doi .org/10.1093/geronb/gbt115
47. Kohout, F. J., Berkman, L. F., Evans, D., & Cornoni-Huntley, J. (1993). Two shorter forms of the CES-D Depression Symptoms Index. Journal of Aging and Health, 5, 179-193. http://dx.doi.org/10.1177/089826439300500202
48. Lehman, D. R., Wortman, C. B., & Williams, A. F. (1987). Long-term effects of losing a spouse or child in a motor vehicle crash. Journal of Personality and Social Psychology, 52, 218-231. http://dx.doi.org/10.1037/0022-3514.52.1.218
49. Lund, D. (1989). Conclusions about bereavement in later life and implications for interventions and future research. In D. Lund (Ed.), Older bereaved spouses: Research with practical applications (pp. 217-231). Amityville, NY: Taylor and Francis/Hemisphere.
50. Luo, Y., Hawkley, L. C., Waite, L. J., & Cacioppo, J. T. (2012). Loneliness, health, and mortality in old age: A national longitudinal study. Social Science & Medicine, 74, 907-914. http://dx.doi.org/10.1016/j .socscimed.2011.11.028
51. Masi, C. M., Chen, H.-Y., Hawkley, L. C., & Cacioppo, J. T. (2011). A meta-analysis of interventions to reduce loneliness. Personality and Social Psychology Review, 15, 219-266. http://dx.doi.org/10.1177/1088868310377394
52. Mazure, C. M. (1998). Life stressors as risk factors in depression. Clinical Psychology: Science and Practice, 5, 291-313. http://dx.doi.org/10.1111/j .1468-2850.1998.tb00151.x
53. Mitchell, A. M., Kim, Y., Prigerson, H. G., & Mortimer-Stephens, M. (2004). Complicated grief in survivors of suicide. Crisis, 25, 12-18. http://dx.doi.org/10.1027/0227-5910.25.1.12
54. Muthén, B. O., & Muthén, L. (2012). Mplus user's guide (7th ed.). Los Angeles, CA: Muthén & Muthén.
55. Myung, W., Song, J., Lim, S.-W., Won, H.-H., Kim, S., Lee, Y., . . . Kim, D. K. (2012). Genetic association study of individual symptoms in depression. Psychiatry Research, 198, 400-406. http://dx.doi.org/10.1016/j.psychres.2011.12.037
56. Nesse, R. M., & Stein, D. J. (2012). Towards a genuinely medical model for psychiatric nosology. BMC Medicine, 10, 1-9. http://dx.doi.org/10.1186/1741-7015-10-5
57. Nolen-Hoeksema, S. (2000). The role of rumination in depressive disorders and mixed anxiety/depressive symptoms. Journal of Abnormal Psychology, 109, 504-511.
58. Østergaard, S. D., Jensen, S. O. W., & Bech, P. (2011). The heterogeneity of the depressive syndrome: When numbers get serious. Acta Psychiatrica Scandinavica, 124, 495-496. http://dx.doi.org/10.1111/j.1600-0447.2011.01744.x
59. Peplau, L., & Perlman, D. (Eds.). (1982). Loneliness: A sourcebook of current theory, research, and therapy. New York, NY: Wiley and Sons.
60. Radloff, L. S. (1977). The CES-D Scale: A self-report depression scale for research in the general population. Applied Psychological Measurement, 1, 385-401. http://dx.doi.org/10.1177/014662167700100306
61. Ravikumar, P., Wainwright, M. J., & Lafferty, J. D. (2010). Highdimensional Ising model selection using _ 1-regularized logistic regression. Annals of Statistics, 38, 1287-1319. http://dx.doi.org/10.1214/09-AOS691
62. R Development Core Team. (2008). R: A language and environment for statistical computing. Vienna, Austria: R Foundation for Statistical Computing.
63. Regier, D. A., Narrow, W. E., Clarke, D. E., Kraemer, H. C., Kuramoto, S. J., Kuhl, E. A., & Kupfer, D. J. (2013). DSM-5 field trials in the United States and Canada, Part II: Test-retest reliability of selected categorical diagnoses. The American Journal of Psychiatry, 170, 59-70. http://dx.doi.org/10.1176/appi.ajp.2012.12070999
64. Robinaugh, D. J., LeBlanc, N. J., Vuletich, H. A., & McNally, R. J. (2014). Network analysis of persistent complex bereavement disorder in conjugally bereaved adults. Journal of Abnormal Psychology, 123, 510-522. http://dx.doi.org/10.1037/abn0000002
65. Rojo-Moreno, L., Livianos-Aldana, L., Cervera-Martínez, G., Dominguez-Carabantes, J. A., & Reig-Cebrian, M. J. (2002). The role of stress in the onset of depressive disorders. Social Psychiatry and Psychiatric Epidemiology, 37, 592-598. http://dx.doi.org/10.1007/s00127-002-0595-y
66. Schmittmann, V. D., Cramer, A. O. J., Waldorp, L. J., Epskamp, S., Kievit, R. A., & Borsboom, D. (2013). Deconstructing the construct: A network perspective on psychological phenomena. New Ideas in Psychology, 31, 43-53. http://dx.doi.org/10.1016/j.newideapsych.2011.02.007
67. Shankar, A., McMunn, A., Banks, J., & Steptoe, A. (2011). Loneliness, social isolation, and behavioral and biological health indicators in older adults. Health Psychology, 30, 377-385. http://dx.doi.org/10.1037/a0022826
68. Shi, J., Potash, J. B., Knowles, J. A., Weissman, M. M., Coryell, W., Scheftner, W. A., . . . Levinson, D. F. (2011). Genome-wide association study of recurrent early-onset major depressive disorder. Molecular Psychiatry, 16, 193-201. http://dx.doi.org/10.1038/mp.2009.124
69. Shrout, P. E., Link, B. G., Dohrenwend, B. P., Skodol, A. E., Stueve, A., & Mirotznik, J. (1989). Characterizing life events as risk factors for depression: The role of fateful loss events. Journal of Abnormal Psychology, 98, 460-467. http://dx.doi.org/10.1037/0021-843X.98.4.460
70. Stroebe, M., Stroebe, W., & Abakoumkin, G. (2005). The broken heart: Suicidal ideation in bereavement. The American Journal of Psychiatry, 162, 2178-2180. http://dx.doi.org/10.1176/appi.ajp.162.11.2178
71. Tansey, K. E., Guipponi, M., Perroud, N., Bondolfi, G., Domenici, E., Evans, D., . . . Uher, R. (2012). Genetic predictors of response to serotonergic and noradrenergic antidepressants in major depressive disorder: A genome-wide analysis of individual-level data and a metaanalysis. PLoS Medicine, 9(10), e1001326. http://dx.doi.org/10.1371/journal.pmed.1001326
72. The Lancet. (2012). Living with grief. Lancet, 379, 589. http://dx.doi.org/10.1016/S0140-6736(12)60248-7
73. Utz, R. L., Swenson, K. L., Caserta, M., Lund, D., & deVries, B. (2014). Feeling lonely versus being alone: Loneliness and social support among recently bereaved persons. The Journals of Gerontology: Series B: Psychological Sciences and Social Sciences, 69B, 85-94. http://dx.doi .org/10.1093/geronb/gbt075
74. van Borkulo, C. D., Borsboom, D., Epskamp, S., Blanken, T. F., Boschloo, L., Schoevers, R. A., & Waldorp, L. J. (2014). A new method for constructing networks from binary data. Scientific Reports, 4, Article No. 5918.
75. van der Heiden, C., Muris, P., & van der Molen, H. T. (2012). Randomized controlled trial on the effectiveness of metacognitive therapy and intolerance-of-uncertainty therapy for generalized anxiety disorder. Behaviour Research and Therapy, 50, 100-109. http://dx.doi.org/10.1016/j.brat.2011.12.005
76. Wakefield, J. C. (1997). Diagnosing DSM-IV-Part I: DSM-IV and the concept of disorder. Behaviour Research and Therapy, 35, 633-649. http://dx.doi.org/10.1016/S0005-7967(97)00018-1
77. Wichers, M. C. (2014). The dynamic nature of depression: A new microlevel perspective of mental disorder that meets current challenges. Psychological Medicine, 616, 1-12.
78. Wilson, R. S., Krueger, K. R., Arnold, S. E., Schneider, J. A., Kelly, J. F., Barnes, L. L., . . . Bennett, D. A. (2007). Loneliness and risk of Alzheimer disease. Archives of General Psychiatry, 64, 234-240. http://dx.doi.org/10.1001/archpsyc.64.2.234
79. Wray, N. R., Pergadia, M. L., Blackwood, D. H. R., Penninx, B. W. J. H., Gordon, S. D., Nyholt, D. R., . . . Sullivan, P. F. (2012). Genome-wide association study of major depressive disorder: New results, metaanalysis, and lessons learned. Molecular Psychiatry, 17, 36-48.
80. Zisook, S., Corruble, E., Duan, N., Iglewicz, A., Karam, E. G., Lanouette, N., . . . Young, I. T. (2012). The bereavement exclusion and DSM-5. Depression and Anxiety, 29, 425-443. http://dx.doi.org/10.1002/da .21927
81. Zisook, S., & Kendler, K. S. (2007). Is bereavement-related depression different than non-bereavement-related depression? Psychological Medicine, 37, 779-794. http://dx.doi.org/10.1017/S0033291707009865
82. Zisook, S., & Shuchter, S. R. (1991). Depression through the first year after the death of a spouse. The American Journal of Psychiatry, 148, 1346-1352.
83. Zuk, O., Hechter, E., Sunyaev, S. R., & Lander, E. S. (2012). The mystery of missing heritability: Genetic interactions create phantom heritability. Proceedings of the National Academy of Sciences, USA, 109, 1193-1198. http://dx.doi.org/10.1073/pnas.1119675109