Female-to-male sex reversal in mice caused by transgenic overexpression of Dmrt1

Development (Cambridge)

Volumn 142, Issue 6, 2015, Pages 1083-1088

  Zhao, Liang ^a   Svingen, Terje ^b   Ng, Ee Ting ^a   Koopman, Peter ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

DM domain genes; Evolution; Mouse; Sex determination; Sox9

Indexed keywords

DMRT1 PROTEIN; DNA BINDING PROTEIN; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG; WNT4 PROTEIN; TRANSCRIPTION FACTOR;

ADULT; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; EMBRYO; FEMALE; FEMALE TO MALE SEX REVERSAL; FETUS; GENE OVEREXPRESSION; GENE REPRESSION; GENITAL SYSTEM; GERM CELL; GONAD; LEYDIG CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SERTOLI CELL; SEX TRANSFORMATION; SEXUAL DEVELOPMENT; SRY GENE; STEROIDOGENESIS; TESTIS CELL; TESTIS SIZE; TRANSGENE; VASCULARIZATION; ANIMAL; BACTERIAL ARTIFICIAL CHROMOSOME; CYTOLOGY; EVOLUTION; FLUORESCENCE MICROSCOPY; GENE EXPRESSION REGULATION; GENE VECTOR; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MOLECULAR CLONING; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; SEX DETERMINATION PROCESS; SEX DIFFERENTIATION; TESTIS; TRANSGENIC MOUSE;

MAMMALIA; METAZOA; MUS;

ANIMALS; BIOLOGICAL EVOLUTION; CHROMOSOMES, ARTIFICIAL, BACTERIAL; CLONING, MOLECULAR; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENETIC VECTORS; GERM CELLS; LEYDIG CELLS; MALE; MICE; MICE, TRANSGENIC; MICROSCOPY, FLUORESCENCE; REAL-TIME POLYMERASE CHAIN REACTION; SEX DETERMINATION PROCESSES; SEX DIFFERENTIATION; TESTIS; TRANSCRIPTION FACTORS;

EID: 84929506393     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.122184     Document Type: Article

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