Household air pollution causes dose-dependent inflammation and altered phagocytosis in human macrophages

American Journal of Respiratory Cell and Molecular Biology

Volumn 52, Issue 5, 2015, Pages 584-593

  Rylance, Jamie ^a,b,d   Fullerton, Duncan G ^a,b   Scriven, James ^a   Aljurayyan, Abdullah N ^a   Mzinza, David ^d   Barrett, Steve ^c   Wright, Adam K A ^a,f   Wootton, Daniel G ^a,b   Glennie, Sarah J ^a,d   Baple, Katy ^a   Knott, Amy ^a   Mortimer, Kevin ^a,b   Russell, David G ^e   Heyderman, Robert S ^d   Gordon, Stephen B ^a  

^a LIVERPOOL SCHOOL OF TROPICAL MEDICINE   (United Kingdom)

^b UNIVERSITY HOSPITAL AINTREE   (United Kingdom)

^c UNIVERSITY OF LIVERPOOL   (United Kingdom)

^d UNIVERSITY OF MALAWI   (Malawi)

^e Cornell University ^*  (United States)

^f and University of Bristol   (United Kingdom)

Author keywords

Alveolar macrophages; Indoor air pollution; Innate immunity; Mycobacterium tuberculosis; Streptococcus pneumoniae

Indexed keywords

FLUORESCEIN ISOTHIOCYANATE; INTERLEUKIN 6; INTERLEUKIN 8; AIR POLLUTANT; AUTACOID; IL6 PROTEIN, HUMAN; IL8 PROTEIN, HUMAN; SOOT;

ADULT; AGED; ARTICLE; CELL FUNCTION; CELL PHAGOCYTOSIS; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; DENSITY GRADIENT CENTRIFUGATION; HUMAN; HUMAN CELL; IN VITRO STUDY; INDOOR AIR POLLUTION; INFLAMMATORY CELL; LUNG ALVEOLUS MACROPHAGE; MALAWI; MYCOBACTERIUM TUBERCULOSIS; NORMAL HUMAN; OXIDATION; PROTEIN SECRETION; QUANTITATIVE ANALYSIS; RESPIRATORY BURST; STREPTOCOCCUS PNEUMONIAE; UNITED KINGDOM; ADVERSE EFFECTS; AIR POLLUTANT; CELL CULTURE; CHEMICALLY INDUCED; CLINICAL TRIAL; DOSE RESPONSE; DRUG EFFECTS; EXPOSURE; HOUSING; IMMUNOLOGY; INNATE IMMUNITY; METABOLISM; MICROBIOLOGY; MIDDLE AGED; MULTICENTER STUDY; PARTICLE SIZE; PHAGOCYTOSIS; PNEUMONIA; SOOT; WOOD; YOUNG ADULT;

CORYNEBACTERINEAE; MYCOBACTERIUM TUBERCULOSIS; STREPTOCOCCUS PNEUMONIAE;

ADULT; AGED; AIR POLLUTANTS; AIR POLLUTION, INDOOR; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENGLAND; HOUSING; HUMANS; IMMUNITY, INNATE; INFLAMMATION MEDIATORS; INHALATION EXPOSURE; INTERLEUKIN-6; INTERLEUKIN-8; MACROPHAGES, ALVEOLAR; MALAWI; MIDDLE AGED; MYCOBACTERIUM TUBERCULOSIS; PARTICLE SIZE; PHAGOCYTOSIS; PNEUMONIA; RESPIRATORY BURST; SOOT; STREPTOCOCCUS PNEUMONIAE; WOOD; YOUNG ADULT;

EID: 84929469767     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2014-0188OC     Document Type: Article

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