Anodal transcranial direct current stimulation to the cerebellum improves handwriting and cyclic drawing kinematics in focal hand dystonia

Frontiers in Human Neuroscience

Volumn 9, Issue MAY, 2015, Pages

  Bradnam, Lynley V ^a,b   Graetz, Lynton J ^b   McDonnell, Michelle N ^c   Ridding, Michael C ^d  

^a UNIVERSITY OF TECHNOLOGY SYDNEY   (Australia)

^b FLINDERS UNIVERSITY   (Australia)

^c UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

^d UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

Cerebellar brain inhibition; Cerebellum; Focal hand dystonia; Handwriting; Kinematics; Transcranial direct current stimulation

Indexed keywords

ADULT; AGED; ANODAL TRANSCRANIAL DIRECT CURRENT STIMULATION; ARM DYSTONIA DISABILITY SCALE; ARTICLE; BRAIN DEPTH STIMULATION; CEREBELLAR BRAIN INHIBITION; CEREBELLUM; CLINICAL ARTICLE; CONTROLLED STUDY; DRAWING; FEMALE; FOCAL HAND DYSTONIA; FUNCTIONAL STATUS ASSESSMENT; HANDWRITING; HUMAN; KINEMATICS; MALE; MIDDLE AGED; MOTOR PERFORMANCE; NERVOUS SYSTEM PARAMETERS; TRANSCRANIAL DIRECT CURRENT STIMULATION; TRANSCRANIAL MAGNETIC STIMULATION; TREATMENT OUTCOME; VERY ELDERLY; WRITER CRAMP RATING SCALE;

EID: 84929457385     PISSN: None     EISSN: 16625161     Source Type: Journal    
DOI: 10.3389/fnhum.2015.00286     Document Type: Article

References (36)

1. Albanese, A., Bhatia, K., Bressman, S. B., Delong, M. R., Fahn, S., Fung, V. S., et al. (2013). Phenomenology and classification of dystonia: a consensus update. Mov. Disord. 28, 863-873. doi: 10.1002/mds.25475
2. Argyelan, M., Carbon, M., Niethammer, M., Ulug, A. M., Voss, H. U., Bressman, S. B., et al. (2009). Cerebellothalamocortical connectivity regulates penetrance in dystonia.J. Neurosci. 29, 9740-9747. doi: 10.1523/JNEUROSCI.2300-09.2009
3. Baarbé, J., Yielder, P., Daligadu, J., Behbahani, H., Haavik, H., and Murphy, B. (2014). A novel protocol to investigate motor training-induced plasticity and sensorimotor integration in the cerebellum and motor cortex. J. Neurophysiol. 111, 715-721. doi: 10.1152/jn.00661.2013
4. Bonnì, S., Ponzo, V., Caltagirone, C., and Koch, G. (2014). Cerebellar theta burst stimulation in stroke patients with ataxia. Funct. Neurol. 7, 1-5. doi: 10.11138/FNeur/2014.29.1.041
5. Bradnam, L., and Barry, C. (2013). The role of the trigeminal sensory nuclear complex in the pathophysiology of craniocervical dystonia. J. Neurosci. 33, 18358-18367. doi: 10.1523/JNEUROSCI.3544-13.2013
6. Brighina, F., Romano, M., Giglia, G., Saia, V., Puma, A., Giglia, F., et al. (2009). Effects of cerebellar TMS on motor cortex of patients with focal dystonia: a preliminary report. Exp. Brain Res. 192, 651-656. doi: 10.1007/s00221-008-1572-9
7. Brusa, L., Ponzo, V., Mastropasqua, C., Picazio, S., Bonnì, S., Di Lorenzo, F., et al. (2014). Theta burst stimulation modulates cerebellar-cortical connectivity in patients with progressive supranuclear palsy. Brain Stimul. 7, 29-35. doi: 10.1016/j.brs.2013.07.003
8. Carrillo, F., Palomar, F. J., Conde, V., Diaz-Corrales, F. J., Porcacchia, P., Fernández-Del-Olmo, M., et al. (2013). Study of cerebello-thalamocortical pathway by transcranial magnetic stimulation in Parkinson's disease. Brain Stimul. 6, 582-589. doi: 10.1016/j.brs.2012.12.004
9. Daskalakis, Z. J., Paradiso, G. O., Christensen, B. K., Fitzgerald, P. B., Gunraj, C., and Chen, R. (2004). Exploring the connectivity between the cerebellum and motor cortex in humans. J. Physiol. 557, 689-700. doi: 10.1113/jphysiol.2003.059808
10. Fahn, S. (1984). The varied clinical expressions of dystonia. Neurol. Clin. 2, 541-554.
11. Ferrucci, R., Brunoni, A. R., Parazzini, M., Vergari, M., Rossi, E., Fumagalli, M., et al. (2013). Modulating human procedural learning by cerebellar transcranial direct current stimulation. Cerebellum 12, 485-492. doi: 10.1007/s12311-012-0436-9
12. Filip, P., Lungu, O. V., and Bares, M. (2013). Dystonia and the cerebellum: a new field of interest in movement disorders? Clin. Neurophysiol. 124, 1269-1276. doi: 10.1016/j.clinph.2013.01.003
13. Galea, J. M., Jayaram, G., Ajagbe, L., and Celnik, P. (2009). Modulation of cerebellar excitability by polarity-specific noninvasive direct current stimulation. J. Neurosci.29, 9115-9122. doi: 10.1523/JNEUROSCI.2184-09.2009
14. Gandiga, P. C., Hummel, F. C., and Cohen, L. G. (2006). Transcranial DC stimulation (tDCS): a tool for double-blind sham-controlled clinical studies in brain stimulation.Clin. Neurophysiol. 117, 845-850. doi: 10.1016/j.clinph.2005.12.003
15. Gilio, F., Currà, A., Inghilleri, M., Lorenzano, C., Suppa, A., Manfredi, M., et al. (2003). Abnormalities of motor cortex excitability preceding movement in patients with dystonia. Brain 126, 1745-1754. doi: 10.1093/brain/awg188
16. Grimaldi, G., Argyropoulos, G. P., Boehringer, A., Celnik, P., Edwards, M. J., Ferrucci, R., et al. (2014). Non-invasive cerebellar stimulation-a consensus paper. Cerebellum13, 121-138. doi: 10.1007/s12311-013-0514-7
17. Hardwick, R. M., Lesage, E., and Miall, R. C. (2014). Cerebellar transcranial magnetic stimulation: the role of coil geometry and tissue depth. Brain Stimul. 7, 643-649. doi: 10.1016/j.brs.2014.04.009
18. Jinnah, H. A., and Hess, E. J. (2006). A new twist on the anatomy of dystonia: the basal ganglia and the cerebellum? Neurology 67, 1740-1741. doi: 10.1212/01.wnl.0000246112.19504.61
19. Kassavetis, P., Hoffland, B. S., Saifee, T. A., Bhatia, K. P., van de Warrenburg, B. P., Rothwell, J. C., et al. (2011). Cerebellar brain inhibition is decreased in active and surround muscles at the onset of voluntary movement. Exp. Brain Res. 209, 437-442. doi: 10.1007/s00221-011-2575-5
20. Koch, G., Mori, F., Marconi, B., Codecà, C., Pecchioli, C., Salerno, S., et al. (2008). Changes in intracortical circuits of the human motor cortex following theta burst stimulation of the lateral cerebellum. Clin. Neurophysiol. 119, 2559-2569. doi: 10.1016/j.clinph.2008.08.008
21. Koch, G., Oliveri, M., Torriero, S., Salerno, S., Lo Gerfo, E., and Caltagirone, C. (2007). Repetitive TMS of cerebellum interferes with millisecond time processing.Exp. Brain Res. 179, 291-299. doi: 10.1007/s00221-006-0791-1
22. Koch, G., Porcacchia, P., Ponzo, V., Carrillo, F., Cáceres-Redondo, M. T., Brusa, L., et al. (2014). Effects of two weeks of cerebellar Theta burst stimulation in cervical dystonia patients. Brain Stimul. 7, 564-572. doi: 10.1016/j.brs.2014.05.002
23. Neychev, V. K., Gross, R. E., Lehéricy, S., Hess, E. J., and Jinnah, H. A. (2011). The functional neuroanatomy of dystonia. Neurobiol. Dis. 42, 185-201. doi: 10.1016/j.nbd.2011.01.026
24. Oldfield, R. C. (1971). The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia 9, 97-113. doi: 10.1016/0028-3932(71)90067-4
25. Prudente, C. N., Pardo, C. A., Xiao, J., Hanfelt, J., Hess, E. J., Ledoux, M. S., et al. (2013). Neuropathology of cervical dystonia. Exp. Neurol. 241, 95-104. doi: 10.1016/j.expneurol.2012.11.019
26. Rossi, S., Hallett, M., Rossini, P. M., Pascual-Leone, A., and Safety of TMS Consensus Group. (2009). Safety, ethical considerations and application guidelines for the use of transcranial magnetic stimulation in clinical practice and research. Clin. Neurophysiol.120, 2008-2039. doi: 10.1016/j.clinph.2009.08.016
27. Rossini, P. M., Barker, A. T., Berardelli, A., Caramia, M. D., Caruso, G., Cracco, R. Q., et al. (1994). Non-invasive electrical and magnetic stimulation of the brain, spinal cord and roots: basic principles and procedures for routine clinical application. Report of an IFCN committee. Electroencephalogr. Clin. Neurophysiol. 91, 79-92. doi: 10.1016/0013-4694(94)90029-9
28. Sadnicka, A., Hamada, M., Bhatia, K. P., Rothwell, J. C., and Edwards, M. J. (2014). Cerebellar stimulation fails to modulate motor cortex plasticity in writing dystonia.Mov. Disord. 29, 1304-1307. doi: 10.1002/mds.25881
29. Sadnicka, A., Hoffland, B. S., Bhatia, K. P., van de Warrenburg, B. P., and Edwards, M. J. (2012). The cerebellum in dystonia-help or hindrance? Clin. Neurophysiol. 123, 65-70. doi: 10.1016/j.clinph.2011.04.027
30. Schabrun, S. M., Stinear, C. M., Byblow, W. D., and Ridding, M. C. (2009). Normalizing motor cortex representations in focal hand dystonia. Cereb. Cortex 19, 1968-1977. doi: 10.1093/cercor/bhn224
31. Standaert, D. G. (2011). Update on the pathology of dystonia. Neurobiol. Dis. 42, 148-151. doi: 10.1016/j.nbd.2011.01.012
32. Ugawa, Y., Uesaka, Y., Terao, Y., Hanajima, R., and Kanazawa, I. (1995). Magnetic stimulation over the cerebellum in humans. Ann. Neurol. 37, 703-713. doi: 10.1002/ana.410370603
33. Weise, D., Gentner, R., Zeller, D., Nagel, A., Reinsberger, C., Rumpf, J. J., et al. (2012). Focal hand dystonia: lack of evidence for abnormality of motor representation at rest.Neurology 78, 122-128. doi: 10.1212/WNL.0b013e31823efce6
34. Wilson, B. K., and Hess, E. J. (2013). Animal models for dystonia. Mov. Disord. 28, 982-989. doi: 10.1002/mds.25526
35. Wissel, J., Kabus, C., Wenzel, R., Klepsch, S., Schwarz, U., Nebe, A., et al. (1996). Botulinum toxin in writer's cramp: objective response evaluation in 31 patients. J. Neurol. Neurosurg. Psychiatry 61, 172-175. doi: 10.1136/jnnp.61.2.172
36. Zeuner, K. E., Peller, M., Knutzen, A., Holler, I., Munchau, A., Hallett, M., et al. (2007). How to assess motor impairment in writer's cramp. Mov. Disord. 22, 1102-1109. doi: 10.1002/mds.21294