Effects of 8 weeks of CPAP on lipid-based oxidative markers in obstructive sleep apnea: A randomized trial

Journal of Sleep Research

Volumn 24, Issue 3, 2015, Pages 339-345

  Sivam, Sheila ^a,b,c   Witting, Paul K ^a   Hoyos, Camilla M ^a,b   Maw, Aung M ^a   Yee, Brendon J ^a,b,c   Grunstein, Ronald R ^a,b,c   Phillips, Craig L ^a,b,d  

^a UNIVERSITY OF SYDNEY   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

^c ROYAL PRINCE ALFRED HOSPITAL   (Australia)

^d ROYAL NORTH SHORE HOSPITAL   (Australia)

Author keywords

Oxidized lipids

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ARACHIDONIC ACID DERIVATIVE; CHOLESTEROL; CHOLESTEROL ESTER; CHOLESTERYL ARACHIDONATE; CHOLESTERYL LINOLEATE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXIDE; LINOLEIC ACID; LIPID; LIPID HYDROPEROXIDE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MARKER; OXYGEN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; BIOLOGICAL MARKER;

ADULT; APNEA HYPOPNEA INDEX; ARTICLE; BODY MASS; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; LIPID OXIDATION; LIPID PEROXIDATION; LIPOPHILICITY; MALE; OXIDATIVE STRESS; OXYGEN SATURATION; POSITIVE END EXPIRATORY PRESSURE; POSITIVE END EXPIRATORY PRESSURE VENTILATOR; POSTPRANDIAL STATE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SHAM PROCEDURE; SLEEP; SLEEP DISORDERED BREATHING; TRIACYLGLYCEROL BLOOD LEVEL; BLOOD; CHEMISTRY; METABOLISM; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL; SLEEP APNEA, OBSTRUCTIVE; TIME;

ANTIOXIDANTS; BIOLOGICAL MARKERS; BODY MASS INDEX; CONTINUOUS POSITIVE AIRWAY PRESSURE; FEMALE; HUMANS; LIPIDS; MALE; MIDDLE AGED; OXIDATIVE STRESS; SLEEP; SLEEP APNEA, OBSTRUCTIVE; TIME FACTORS; VITAMIN E;

EID: 84929453769     PISSN: 09621105     EISSN: 13652869     Source Type: Journal    
DOI: 10.1111/jsr.12271     Document Type: Article

References (43)

1. Alonso-Fernandez, A., Garcia-Rio, F., Arias, M. A. et al. Effects of CPAP on oxidative stress and nitrate efficiency in sleep apnoea: a randomised trial. Thorax, 2009, 64: 581-586.
2. American Academy of Sleep Medicine Task Force. Sleep-related breathing disorders in adults: recommendations for syndrome definition and measurement techniques in clinical research. The Report of an American Academy of Sleep Medicine Task Force. Sleep, 1999, 22: 667-689.
3. Arias, M. A., Garcia-Rio, F., Alonso-Fernandez, A., Mediano, O., Martinez, I. and Villamor, J. Obstructive sleep apnea syndrome affects left ventricular diastolic function: effects of nasal continuous positive airway pressure in men. Circulation, 2005, 112: 375-383.
4. Barcelo, A., Miralles, C., Barbe, F., Vila, M., Pons, S. and Agusti, A. G. Abnormal lipid peroxidation in patients with sleep apnoea. Eur. Respir. J., 2000, 16: 644-647.
5. Barcelo, A., Barbe, F., De La Pena, M. et al. Antioxidant status in patients with sleep apnoea and impact of continuous positive airway pressure treatment. Eur. Respir. J., 2006, 27: 756-760.
6. Carpagnano, G. E., Kharitonov, S. A., Resta, O., Foschino-Barbaro, M. P., Gramiccioni, E. and Barnes, P. J. 8-Isoprostane, a marker of oxidative stress, is increased in exhaled breath condensate of patients with obstructive sleep apnea after night and is reduced by continuous positive airway pressure therapy. Chest, 2003, 124: 1386-1392.
7. Celec, P., Jurkovicova, I., Buchta, R. et al. Antioxidant vitamins prevent oxidative and carbonyl stress in an animal model of obstructive sleep apnea. Sleep Breath., 2013, 17: 867-871.
8. Christou, K., Moulas, A. N., Pastaka, C. and Gourgoulianis, K. I. Antioxidant capacity in obstructive sleep apnea patients. Sleep Med., 2003, 4: 225-228.
9. Christou, K., Kostikas, K., Pastaka, C., Tanou, K., Antoniadou, I. and Gourgoulianis, K. I. Nasal continuous positive airway pressure treatment reduces systemic oxidative stress in patients with severe obstructive sleep apnea syndrome. Sleep Med., 2009, 10: 87-94.
10. Davies, S. S. and Roberts, L. J. 2nd F2-isoprostanes as an indicator and risk factor for coronary heart disease. Free Radic. Biol. Med., 2011, 50: 559-566.
11. Ehara, S., Ueda, M., Naruko, T. et al. Elevated levels of oxidized low density lipoprotein show a positive relationship with the severity of acute coronary syndromes. Circulation, 2001, 103: 1955-1960.
12. Gomez, M., Vila, J., Elosua, R. et al. Relationship of lipid oxidation with subclinical atherosclerosis and 10-year coronary events in general population. Atherosclerosis, 2014, 232: 134-140.
13. Grebe, M., Eisele, H. J., Weissmann, N. et al. Antioxidant vitamin C improves endothelial function in obstructive sleep apnea. Am. J. Respir. Crit. Care Med., 2006, 173: 897-901.
14. Grimsrud, P. A., Xie, H., Griffin, T. J. and Bernlohr, D. A. Oxidative stress and covalent modification of protein with bioactive aldehydes. J. Biol. Chem., 2008, 283: 21837-21841.
15. Halliwell, B. and Gutteridge, J. M. Role of free radicals and catalytic metal ions in human disease: an overview. Methods Enzymol., 1990, 186: 1-85.
16. Halliwell, B. and Lee, C. Y. J. Using isoprostanes as biomarkers of oxidative stress: some rarely considered issues. Antioxid. Redox Signal., 2009, 13: 145-156.
17. Helin, P. and Lorenzen, I. Arteriosclerosis in rabbit aorta induced by systemic hypoxia. Biochemical and morphologic studies. Angiology, 1969, 20: 1-12.
18. Itzhaki, S., Dorchin, H., Clark, G., Lavie, L., Lavie, P. and Pillar, G. The effects of 1-year treatment with a herbst mandibular advancement splint on obstructive sleep apnea, oxidative stress, and endothelial function. Chest, 2007, 131: 740-749.
19. Janicka, M., Kot-Wasik, A., Kot, J. and Namiesnik, J. Isoprostanes-biomarkers of lipid peroxidation: their utility in evaluating oxidative stress and analysis. Int. J. Mol. Sci., 2010, 11: 4631-4659.
20. Jelic, S., Padeletti, M., Kawut, S. M. et al. Inflammation, oxidative stress, and repair capacity of the vascular endothelium in obstructive sleep apnea. Circulation, 2008, 117: 2270-2278.
21. Kent, B. D., Ryan, S. and Mcnicholas, W. T. Obstructive sleep apnea and inflammation: relationship to cardiovascular co-morbidity. Respir. Physiol. Neurobiol., 2011, 178: 475-481.
22. Lau, A. K., Chaufour, X., Mclachlan, C. et al. Intimal thickening after arterial balloon injury is increased by intermittent repetitive hypoxia, but intermittent repetitive hyperoxia is not protective. Atherosclerosis, 2006, 185: 254-263.
23. Lavie, L. Oxidative stress-a unifying paradigm in obstructive sleep apnea and comorbidities. Prog. Cardiovasc. Dis., 2009, 51: 303-312.
24. Lavie, L., Vishnevsky, A. and Lavie, P. Evidence for lipid peroxidation in obstructive sleep apnea. Sleep, 2004, 27: 123-128.
25. Linna, M., Ahotupa, M., Lopponen, M. K., Irjala, K. and Vasankari, T. Circulating oxidised LDL lipids, when proportioned to HDL-c, emerged as a risk factor of all-cause mortality in a population-based survival study. Age Ageing, 2013, 42: 110-113.
26. Marin, J. M., Carrizo, S. J., Vicente, E. and Agusti, A. G. Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: an observational study. Lancet, 2005, 365: 1046-1053.
27. Minoguchi, K., Yokoe, T., Tanaka, A. et al. Association between lipid peroxidation and inflammation in obstructive sleep apnoea. Eur. Respir. J., 2006, 28: 378-385.
28. Moon, G. J., Kim, S. J., Cho, Y. H., Ryoo, S. and Bang, O. Y. Antioxidant effects of statins in patients with atherosclerotic cerebrovascular disease. J. Clin. Neurol., 2014, 10: 140-147.
29. Moselhy, H. F., Reid, R. G., Yousef, S. and Boyle, S. P. A specific, accurate, and sensitive measure of total plasma malondialdehyde by HPLC. J. Lipid Res., 2013, 54: 852-858.
30. Nourooz-Zadeh, J. Key issues in F2-isoprostane analysis. Biochem. Soc. Trans., 2008, 36: 1060-1065.
31. Phillips, C. L., Yee, B. J., Marshall, N. S., Liu, P. Y., Sullivan, D. R. and Grunstein, R. R. Continuous positive airway pressure reduces post prandial lipidemia in obstructive sleep apnea. A randomised, placebo controlled crossover trial. Am. J. Respir. Crit. Care Med., 2011, 184: 355-361.
32. Phillips, C. L., Butlin, M., Wong, K. K. and Avolio, A. P. Is obstructive sleep apnoea causally related to arterial stiffness? A critical review of the experimental evidence. Sleep Med. Rev., 2013, 17: 7-18.
33. Raitakari, O. T., McCredie, R. J., Witting, P. et al. Coenzyme Q improves LDL resistance to ex vivo oxidation but does not enhance endothelial function in hypercholesterolemic young adults. Free Radic. Biol. Med., 2000, 28: 1100-1105.
34. Robinson, G. V., Pepperell, J. C., Segal, H. C., Davies, R. J. and Stradling, J. R. Circulating cardiovascular risk factors in obstructive sleep apnoea: data from randomised controlled trials. Thorax, 2004, 59: 777-782.
35. Steinberg, D. The LDL modification hypothesis of atherogenesis: an update. J. Lipid Res., 2009, 50(Suppl): S376-S381.
36. Suzuki, Y. J., Jain, V., Park, A. M. and Day, R. M. Oxidative stress and oxidant signaling in obstructive sleep apnea and associated cardiovascular diseases. Free Radic. Biol. Med., 2006, 40: 1683-1692.
37. Svatikova, A., Wolk, R., Lerman, L. O. et al. Oxidative stress in obstructive sleep apnoea. Eur. Heart J., 2005, 26: 2435-2439.
38. Valko, M., Leibfritz, D., Moncol, J., Cronin, M. T., Mazur, M. and Telser, J. Free radicals and antioxidants in normal physiological functions and human disease. Int. J. Biochem. Cell Biol., 2007, 39: 44-84.
39. Witting, P. K., Mohr, D. and Stocker, R. Assessment of prooxidant activity of vitamin E in human low-density lipoprotein and plasma. Methods Enzymol., 1999, 299: 362-375.
40. Yamamoto, Y., Brodsky, M. H., Baker, J. C. and Ames, B. N. Detection and characterization of lipid hydroperoxides at picomole levels by high-performance liquid chromatography. Anal. Biochem., 1987, 160: 7-13.
41. Yamauchi, M., Nakano, H., Maekawa, J. et al. Oxidative stress in obstructive sleep apnea. Chest, 2005, 127: 1674-1679.
42. Yin, H., Morrow, J. D. and Porter, N. A. Identification of a novel class of endoperoxides from arachidonate autoxidation. J. Biol. Chem., 2004, 279: 3766-3776.
43. Young, T., Palta, M., Dempsey, J., Skatrud, J., Weber, S. and Badr, S. The occurrence of sleep-disordered breathing among middle-aged adults. N. Engl. J. Med., 1993, 328: 1230-1235.