Long-term safety and efficacy of stiripentol for the treatment of Dravet syndrome: A multicenter, open-label study in Japan

Epilepsy Research

Volumn 113, Issue , 2015, Pages 90-97

  Inoue, Yushi ^a   Ohtsuka, Yoko ^b   Ikeda, Hiroko ^c   Yoshinaga, Harumi ^d   Kobayashi, Katsuhiro ^d   Tohyama, Jun ^e   Baba, Hiroshi ^f   Ishitsu, Takateru ^g   Nishizato, Chizuru ^g   Osawa, Makiko ^h   Suzuki, Yasuhiro ⁱ   Takeuchi, Yoshihiro ^j   Osaka, Hitoshi ^k   Maegaki, Yoshihiro ^l   Kubota, Masaya ^m   Fujiwara, Tateki ^a   Ogino, Tatsuya ⁿ  

^a SHIZUOKA INSTITUTE OF EPILEPSY AND NEUROLOGICAL DISORDERS   (Japan)

^b OKAYAMA UNIVERSITY   (Japan)

^c Department of Neurology   (Japan)

^d OKAYAMA UNIVERSITY HOSPITAL   (Japan)

^e NISHI NIIGATA CHUO NATIONAL HOSPITAL   (Japan)

^f NATIONAL HOSPITAL ORGANIZATION NAGASAKI MEDICAL CENTER   (Japan)

^g Kumamoto Saishunsou National Hospital   (Japan)

^h TOKYO WOMEN S MEDICAL UNIVERSITY MEDICAL CENTER EAST   (Japan)

ⁱ RESEARCH INSTITUTE FOR MATERNAL AND CHILD HEALTH   (Japan)

^j SHIGA UNIVERSITY OF MEDICAL SCIENCE HOSPITAL   (Japan)

^k KANAGAWA CHILDREN'S MEDICAL CENTER   (Japan)

^l TOTTORI UNIVERSITY   (Japan)

^m NATIONAL CENTER FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

ⁿ Chugoku Gakuen University   (Japan)

more..

Author keywords

Dravet syndrome; Efficacy; Long term administration; Severe myoclonic epilepsy in infancy; Stiripentol; Tolerability

Indexed keywords

ALKALINE PHOSPHATASE; CLOBAZAM; GAMMA GLUTAMYLTRANSFERASE; STIRIPENTOL; VALPROIC ACID; 1,3 DIOXOLANE DERIVATIVE; ANTICONVULSIVE AGENT; BENZODIAZEPINE DERIVATIVE;

ADD ON THERAPY; ADULT; ARTICLE; ATAXIA; BRONCHITIS; CHILD; CLINICAL ARTICLE; CONSTIPATION; DECREASED APPETITE; DIARRHEA; DOSE RESPONSE; DRUG DOSE ESCALATION; DRUG DOSE REDUCTION; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; DRY SKIN; FEMALE; HUMAN; INSOMNIA; JAPAN; LOSS OF APPETITE; MALE; MALNUTRITION; MULTICENTER STUDY; MUSCLE HYPOTONIA; NEUTROPENIA; OPEN STUDY; PNEUMONIA; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; SEVERE MYOCLONIC EPILEPSY IN INFANCY; SOMNOLENCE; THROMBOCYTOPENIA; TREATMENT DURATION; TREATMENT OUTCOME; UNSPECIFIED SIDE EFFECT; WEIGHT REDUCTION; YOUNG ADULT; ADOLESCENT; CLINICAL TRIAL; DRUG COMBINATION; EPILEPSIES, MYOCLONIC; INFANT;

ADOLESCENT; ADULT; ANTICONVULSANTS; BENZODIAZEPINES; CHILD; CHILD, PRESCHOOL; DIOXOLANES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG THERAPY, COMBINATION; EPILEPSIES, MYOCLONIC; FEMALE; HUMANS; INFANT; JAPAN; MALE; TREATMENT OUTCOME; VALPROIC ACID; YOUNG ADULT;

EID: 84929429500     PISSN: 09201211     EISSN: 18726844     Source Type: Journal    
DOI: 10.1016/j.eplepsyres.2015.03.012     Document Type: Article

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