Clindamycin resistant emm33 Streptococcus pyogenes emerged among invasive infections in Helsinki metropolitan area, Finland, 2012 to 2013

Eurosurveillance

Volumn 20, Issue 18, 2015, Pages

  Pesola, A K ^a   Sihvonen, R ^a   Lindholm, L ^b   Patari Sampo A ^a  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

AZITHROMYCIN; BACTERIAL DNA; C REACTIVE PROTEIN; CLINDAMYCIN; DOXYCYCLINE; ERYTHROMYCIN; LEVOFLOXACIN; MOXIFLOXACIN; TELITHROMYCIN; TETRACYCLINE; VANCOMYCIN; ANTIINFECTIVE AGENT;

ADOLESCENT; ADULT; AGED; ANTIBIOTIC RESISTANCE; ARTICLE; BACTEREMIA; BACTERIUM ISOLATE; BLOOD CULTURE; CHILD; DISK DIFFUSION; FEMALE; FINLAND; GENE EXPRESSION; GROUP A STREPTOCOCCAL INFECTION; HUMAN; INFANT; LEUKOCYTE COUNT; MALE; MIDDLE AGED; MINIMUM INHIBITORY CONCENTRATION; MULTIPLEX POLYMERASE CHAIN REACTION; NEWBORN; NONHUMAN; PHENOTYPE; SKIN INFECTION; SOFT TISSUE INFECTION; STREPTOCOCCUS DYSGALACTIAE; STREPTOCOCCUS GROUP A; STREPTOCOCCUS PYOGENES; VERY ELDERLY; BLOOD; DRUG EFFECTS; GENETICS; ISOLATION AND PURIFICATION; MICROBIAL SENSITIVITY TEST; STREPTOCOCCAL INFECTIONS; URBAN POPULATION;

ADULT; AGED; AGED, 80 AND OVER; ANTI-BACTERIAL AGENTS; CLINDAMYCIN; DRUG RESISTANCE, BACTERIAL; ERYTHROMYCIN; FEMALE; FINLAND; HUMANS; MALE; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; PHENOTYPE; STREPTOCOCCAL INFECTIONS; STREPTOCOCCUS PYOGENES; URBAN POPULATION;

EID: 84929429326     PISSN: 1025496X     EISSN: 15607917     Source Type: Journal    
DOI: 10.2807/1560-7917.ES2015.20.18.21117     Document Type: Article

References (28)

1. Cunningham MW. Pathogenesis of group A streptococcal infections. Clin Microbiol Rev. 2000;13(3):470-511. http://dx.doi.org/10.1128/CMR.13.3.470-511.2000: PMID:10885988
2. McMillan DJ, Drèze PA, Vu T, Bessen DE, Guglielmini J, Steer AC, et al. Updated model of group A Streptococcus M proteins based on a comprehensive worldwide study. Clin Microbiol Infect. 2013;19(5):E222-9. http://dx.doi.org/10.1111/1469-0691.12134: PMID:23464795
3. Metzgar D, McDonough EA, Hansen CJ, Blaesing CR, Baynes D, Hawksworth AW, et al. Local changes in rates of group A Streptococcus disease and antibiotic resistance are associated with geographically widespread strain turnover events. Virulence. 2010;1(4):247-53. http://dx.doi.org/10.4161/viru.1.4.11979: PMID:21178449
4. Perez-Trallero E, Marimón JM, Montes M, Orden B, de Pablos M. Clonal differences among erythromycin-resistant Streptococcus pyogenes in Spain. Emerg Infect Dis. 1999;5(2):235-40. http://dx.doi.org/10.3201/eid0502.990207: PMID:10221875
5. Martin JM, Green M, Barbadora KA, Wald ER. Erythromycinresistant group A streptococci in schoolchildren in Pittsburgh. N Engl J Med. 2002;346(16):1200-6. http://dx.doi.org/10.1056/NEJMoa013169: PMID:11961148
6. Green M, Martin JM, Barbadora KA, Beall B, Wald ER. Reemergence of macrolide resistance in pharyngeal isolates of group a streptococci in southwestern Pennsylvania. Antimicrob Agents Chemother. 2004;48(2):473-6. http://dx.doi.org/10.1128/AAC.48.2.473-476.2004: PMID:14742197
7. Reinert RR, Lütticken R, Sutcliffe JA, Tait-Kamradt A, Cil MY, Schorn HM, et al. Clonal relatedness of erythromycin-resistant Streptococcus pyogenes isolates in Germany. Antimicrob Agents Chemother. 2004;48(4):1369-73. http://dx.doi.org/10.1128/AAC.48.4.1369-1373.2004: PMID:15047546
8. Richter SS, Heilmann KP, Beekmann SE, Miller NJ, Miller AL, Rice CL, et al. Macrolide-resistant Streptococcus pyogenes in the United States, 2002-2003. Clin Infect Dis. 2005;41(5):599-608. http://dx.doi.org/10.1086/432473: PMID:16080080
9. Gunell M, Hakanen A, Jalava J, Nissinen A, Rantakokko-Jalava K, Saha K, et al. Antimicrobial Resistance in Finland - Finres. 2012. Helsinki: National Institute of Health and Welfare; 2012. Available from: http://urn.fi/URN:ISBN:978-952-302-183-9
10. Vaara M. HUSRES Annual Report 2012. HUS; 2012. Available from: http://www.hus.fi/ammattilaiselle/huslab-ammattilaisille/tilastot/Bakteerilydsten%20mikrobilkeherkkyystilastoja%20Helsin/Herkkyystilastot%20(Helsinki%20ja%20Uusimaa)%202012.pdf
11. Siljander T, Karppelin M, Vähäkuopus S, Syrjänen J, Toropainen M, Kere J, et al. Acute bacterial, nonnecrotizing cellulitis in Finland: microbiological findings. Clin Infect Dis. 2008;46(6):855-61. http://dx.doi.org/10.1086/527388: PMID:18260753
12. Jalava J, Marttila H. Application of molecular genetic methods in macrolide, lincosamide and streptogramin resistance diagnostics and in detection of drug-resistant Mycobacterium tuberculosis. APMIS. 2004;112(11-12):838-55. http://dx.doi.org/10.1111/j.1600-0463.2004.apm11211-1209.x: PMID:15638840
13. Seppälä H, Skurnik M, Soini H, Roberts MC, Huovinen P. A novel erythromycin resistance methylase gene (ermTR) in Streptococcus pyogenes. Antimicrob Agents Chemother. 1998;42(2):257-62: PMID:9527769
14. Tyrrell GJ, Lovgren M, St Jean T, Hoang L, Patrick DM, Horsman G, et al. Epidemic of group A Streptococcus M/emm59 causinginvasive disease in Canada. Clin Infect Dis. 2010;51(11):1290-7. http://dx.doi.org/10.1086/657068: PMID:21034198
15. Eriksson BK, Andersson J, Holm SE, Norgren M. Epidemiological and clinical aspects of invasive group A streptococcal infections and the streptococcal toxic shock syndrome. Clin Infect Dis. 1998;27(6):1428-36. http://dx.doi.org/10.1086/515012: PMID:9868656
16. Bessen DE, Sotir CM, Readdy TL, Hollingshead SK. Genetic correlates of throat and skin isolates of group A streptococci. J Infect Dis. 1996;173(4):896-900. http://dx.doi.org/10.1093/infdis/173.4.896: PMID:8603968
17. Svensson MD, Sjöbring U, Bessen DE. Selective distribution of a high-affinity plasminogen-binding site among group A streptococci associated with impetigo. Infect Immun. 1999;67(8):3915-20: PMID:10417156
18. Sanderson-Smith M, De Oliveira DMP, Guglielmini J, McMillan DJ, Vu T, Holien JK, et al.; M Protein Study Group. A systematic and functional classification of Streptococcus pyogenes that serves as a new tool for molecular typing and vaccine development. J Infect Dis. 2014;210(8):1325-38. http://dx.doi.org/10.1093/infdis/jiu260: PMID:24799598
19. Lamagni TL, Neal S, Keshishian C, Hope V, George R, Duckworth G, et al. Epidemic of severe Streptococcus pyogenes infections in injecting drug users in the UK, 2003-2004. Clin Microbiol Infect. 2008;14(11):1002-9. http://dx.doi.org/10.1111/j.1469-0691.2008.02076.x: PMID:19040471
20. Lamagni TL, Darenberg J, Luca-Harari B, Siljander T, Efstratiou A, Henriques-Normark B, et al.; Strep-EURO Study Group. Epidemiology of severe Streptococcus pyogenes disease in Europe. J Clin Microbiol. 2008;46(7):2359-67. http://dx.doi.org/10.1128/JCM.00422-08: PMID:18463210
21. Darenberg J, Henriques-Normark B, Lepp T, Tegmark-Wisell K, Tegnell A, Widgren K. Increased incidence of invasive group A streptococcal infections in Sweden, January 2012-February 2013. Euro Surveill. 2013;18(14):20443. http://dx.doi.org/10.2807/1560-7917.ES2013.18.14.20443: PMID:23594518
22. Sutcliffe J, Tait-Kamradt A, Wondrack L. Streptococcus pneumoniae and Streptococcus pyogenes resistant to macrolides but sensitive to clindamycin: a common resistance pattern mediated by an efflux system. Antimicrob Agents Chemother. 1996;40(8):1817-24: PMID:8843287
23. Kataja J, Huovinen P, Muotiala A, Vuopio-Varkila J, Efstratiou A, Hallas G, et al.; Finnish Study Group for Antimicrobial Resistance. Clonal spread of group A streptococcus with the new type of erythromycin resistance. J Infect Dis. 1998;177(3):786-9. http://dx.doi.org/10.1086/517809: PMID:9498465
24. Leclercq R. Mechanisms of resistance to macrolides and lincosamides: nature of the resistance elements and their clinical implications. Clin Infect Dis. 2002;34(4):482-92. http://dx.doi.org/10.1086/324626: PMID:11797175
25. Kataja J, Huovinen P, Skurnik M, Seppälä H; The Finnish Study Group for Antimicrobial Resistance. Erythromycin resistance genes in group A streptococci in Finland. Antimicrob Agents Chemother. 1999;43(1):48-52: PMID:9869564
26. Bemer-Melchior P, Juvin M-E, Tassin S, Bryskier A, Schito GC, Drugeon H-B. In vitro activity of the new ketolide telithromycin compared with those of macrolides against Streptococcus pyogenes: influences of resistance mechanisms and methodological factors. Antimicrob Agents Chemother. 2000;44(11):2999-3002. http://dx.doi.org/10.1128/AAC.44.11.2999-3002.2000: PMID:11036012
27. Giovanetti E, Montanari MP, Marchetti F, Varaldo PE. In vitro activity of ketolides telithromycin and HMR 3004 against italian isolates of Streptococcus pyogenes and Streptococcus pneumoniae with different erythromycin susceptibility. J Antimicrob Chemother. 2000;46(6):905-8. http://dx.doi.org/10.1093/jac/46.6.905: PMID:11102408
28. Zimbelman J, Palmer A, Todd J. Improved outcome of clindamycin compared with beta-lactam antibiotic treatment for invasive Streptococcus pyogenes infection. Pediatr Infect Dis J. 1999;18(12):1096-100. http://dx.doi.org/10.1097/00006454-199912000-00014: PMID:10608632