Racial disparities in outcomes of adult heart transplantation

Circulation

Volumn 131, Issue 10, 2015, Pages 882-889

  Kilic, Arman ^a   Higgins, Robert S D ^b   Whitson, Bryan A ^b   Kilic, Ahmet ^a,b  

^a JOHNS HOPKINS HOSPITAL   (United States)

^b THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

Author keywords

Heart failure; Morbidity; Mortality; Surgery; Transplantation

Indexed keywords

ADULT; ARTICLE; CARDIOVASCULAR MORTALITY; CARDIOVASCULAR RISK; CONTROLLED STUDY; CORRELATION ANALYSIS; EDUCATIONAL STATUS; FEMALE; HEALTH INSURANCE; HEART TRANSPLANTATION; HISPANIC; HUMAN; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RACE DIFFERENCE; RISK ASSESSMENT; TASK PERFORMANCE; BLACK PERSON; CAUCASIAN; CLINICAL TRIAL; COMPARATIVE STUDY; ETHNOLOGY; FOLLOW UP; HEALTH CARE DISPARITY; HEART FAILURE; MIDDLE AGED; MORTALITY; MULTICENTER STUDY; MULTIVARIATE ANALYSIS; REGISTER; RETROSPECTIVE STUDY; RISK FACTOR; SURVIVAL RATE; TREATMENT OUTCOME;

ADULT; AFRICAN CONTINENTAL ANCESTRY GROUP; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; FOLLOW-UP STUDIES; HEALTHCARE DISPARITIES; HEART FAILURE; HEART TRANSPLANTATION; HISPANIC AMERICANS; HUMANS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; REGISTRIES; RETROSPECTIVE STUDIES; RISK FACTORS; SURVIVAL RATE; TREATMENT OUTCOME;

EID: 84929428616     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.114.011676     Document Type: Article

References (28)

1. Liu V, Bhattacharya J, Weill D, Hlatky MA. Persistent racial disparities in survival after heart transplantation. Circulation. 2011;123:1642-1649. doi: 10.1161/CIRCULATIONAHA.110.976811.
2. Singh TP, Almond C, Givertz MM, Piercey G, Gauvreau K. Improved survival in heart transplant recipients in the United States: racial differences in era effect. Circ Heart Fail. 2011;4:153-160. doi: 10.1161/CIRCHEARTFAILURE.110.957829.
3. Kilic A, Weiss ES, George TJ, Arnaoutakis GJ, Yuh DD, Shah AS, Conte JV. What predicts long-term survival after heart transplantation? An analysis of 9,400 ten-year survivors. Ann Thorac Surg. 2012;93:699-704. doi: 10.1016/j.athoracsur.2011.09.037.
4. Morris AA, Cole RT, Veledar E, Bellam N, Laskar SR, Smith AL, Gebel HM, Bray RA, Butler J. Influence of race/ethnic differences in pre-transplantation panel reactive antibody on outcomes in heart transplant recipients. J Am Coll Cardiol. 2013;62:2308-2315. doi: 10.1016/j.jacc.2013.06.054.
5. Allen JG, Weiss ES, Arnaoutakis GJ, Russell SD, Baumgartner WA, Conte JV, Shah AS. The impact of race on survival after heart transplantation: an analysis of more than 20,000 patients. Ann Thorac Surg. 2010;89:1956-1963. doi: 10.1016/j.athoracsur.2010.02.093.
6. Weiss ES, Allen JG, Arnaoutakis GJ, George TJ, Russell SD, Shah AS, Conte JV. Creation of a quantitative recipient risk index for mortality prediction after cardiac transplantation (IMPACT). Ann Thorac Surg. 2011;92:914-921. doi: 10.1016/j.athoracsur.2011.04.030.
7. Kilic A, Allen JG, Weiss ES. Validation of the United States-derived Index for Mortality Prediction After Cardiac Transplantation (IMPACT) using international registry data. J Heart Lung Transplant. 2013;32:492-498. doi: 10.1016/j.healun.2013.02.001.
8. Weiss ES, Allen JG, Kilic A, Russell SD, Baumgartner WA, Conte JV, Shah AS. Development of a quantitative donor risk index to predict short-term mortality in orthotopic heart transplantation. J Heart Lung Transplant. 2012;31:266-273. doi: 10.1016/j.healun.2011.10.004.
9. Rogers CA, Akan E, Bonser RS, Banner NR. US-derived quantitative donor risk score predicts mortality after orthotopic heart transplantation in the UK. J Heart Lung Transplant. 2011;30:S120.
10. Ayanian JZ, Cleary PD, Weissman JS, Epstein AM. The effect of patients' preferences on racial differences in access to renal transplantation. N Engl J Med. 1999;341:1661-1669. doi: 10.1056/NEJM199911253412206.
11. Isaacs RB, Lobo PI, Nock SL, Hanson JA, Ojo AO, Pruett TL. Racial disparities in access to simultaneous pancreas-kidney transplantation in the United States. Am J Kidney Dis. 2000;36:526-533. doi: 10.1053/ajkd.2000.9793.
12. Higgins RS, Fishman JA. Disparities in solid organ transplantation for ethnic minorities: facts and solutions. Am J Transplant. 2006;6:2556-2562. doi: 10.1111/j.1600-6143.2006.01514.x.
13. Bibbins-Domingo K, Pletcher MJ, Lin F, Vittinghoff E, Gardin JM, Arynchyn A, Lewis CE, Williams OD, Hulley SB. Racial differences in incident heart failure among young adults. N Engl J Med. 2009;360:1179-1190. doi: 10.1056/NEJMoa0807265.
14. Carson P, Ziesche S, Johnson G, Cohn JN. Racial differences in response to therapy for heart failure: analysis of the vasodilator-heart failure trials. Vasodilator-Heart Failure Trial Study Group. J Card Fail. 1999;5:178-187.
15. Exner DV, Dries DL, Domanski MJ, Cohn JN. Lesser response to angiotensin-converting-enzyme inhibitor therapy in black as compared with white patients with left ventricular dysfunction. N Engl J Med. 2001;344:1351-1357. doi: 10.1056/NEJM200105033441802.
16. Yancy CW, Fowler MB, Colucci WS, Gilbert EM, Bristow MR, Cohn JN, Lukas MA, Young ST, Packer M; U.S. Carvedilol Heart Failure Study Group. Race and the response to adrenergic blockade with carvedilol in patients with chronic heart failure. N Engl J Med. 2001;344:1358-1365. doi: 10.1056/NEJM200105033441803.
17. Stehlik J, Starling RC, Movsesian MA, Fang JC, Brown RN, Hess ML, Lewis NP, Kirklin JK; Cardiac Transplant Research Database Group. Utility of long-term surveillance endomyocardial biopsy: a multi-institutional analysis. J Heart Lung Transplant. 2006;25:1402-1409. doi: 10.1016/j.healun.2006.10.003.
18. Mehra MR, Uber PA, Scott RL, Park MH. Ethnic disparity in clinical outcome after heart transplantation is abrogated using tacrolimus and mycophenolate mofetil-based immunosuppression. Transplantation. 2002;74:1568-1573. doi: 10.1097/01.TP.0000036054.13870.E7.
19. United States Census Bureau Population. Marital status and living arrangements. http://www.census.gov/hhes/families/data/cps2013A.htmlhttp://www.census.gov/hhes/families/data/cps2013A.html. Accessed April 21, 2014.
20. Tam V, Arnaoutakis GJ, George TJ, Russell SD, Merlo CA, Conte JV, Baumgartner WA, Shah AS. Marital status improves survival after orthotopic heart transplantation. J Heart Lung Transplant. 2011;30:1389-1394. doi: 10.1016/j.healun.2011.07.020.
21. Centers for Medicare and Medicaid Services. Medicaid data sources. http://www.cms.gov. Accessed April 23, 2014.
22. Allen JG, Weiss ES, Arnaoutakis GJ, Russell SD, Baumgartner WA, Shah AS, Conte JV. Insurance and education predict long-term survival after orthotopic heart transplantation in the United States. J Heart Lung Transplant. 2012;31:52-60. doi: 10.1016/j.healun.2011.07.019.
23. Johnson MR, Meyer KH, Haft J, Kinder D, Webber SA, Dyke DB. Heart transplantation in the United States, 1999-2008. Am J Transplant. 2010;10(4 pt 2):1035-1046. doi: 10.1111/j.1600-6143.2010.03042.x.
24. Kilic A, Weiss ES, Yuh DD, Shah AS, Cameron DE, Baumgartner WA, Conte JV. Institutional factors beyond procedural volume significantly impact center variability in outcomes after orthotopic heart transplantation. Ann Surg. 2012;256:616-623. doi: 10.1097/SLA.0b013e31826b4bc9.
25. Dimick JB, Pronovost PJ, Heitmiller RF, Lipsett PA. Intensive care unit physician staffing is associated with decreased length of stay, hospital cost, and complications after esophageal resection. Crit Care Med. 2001;29:753-758.
26. Aiken LH, Clarke SP, Sloane DM, Sochalski J, Silber JH. Hospital nurse staffing and patient mortality, nurse burnout, and job dissatisfaction. JAMA. 2002;288:1987-1993.
27. Low DE, Kunz S, Schembre D, Otero H, Malpass T, Hsi A, Song G, Hinke R, Kozarek RA. Esophagectomy-it's not just about mortality anymore: standardized perioperative clinical pathways improve outcomes in patients with esophageal cancer. J Gastrointest Surg. 2007;11:1395-1402. doi: 10.1007/s11605-007-0265-1.
28. American Heart Association. Get with the guidelines. http://www.heart. org/HEARTORG/HealthcareResearch/GetWithTheGuidelinesHFStroke/Get-With-The-Guidelines---HFStroke-UCM-001099-SubHomePage. jsp. Accessed September 16, 2014.