Improved survival in heart transplant recipients in the united states racial differences in era effect

Circulation: Heart Failure

Volumn 4, Issue 2, 2011, Pages 153-160

  Singh, Tajinder P ^a,b,c   Almond, Christopher ^a,c   Givertz, Michael M ^b,d   Piercey, Gary ^a   Gauvreau, Kimberlee ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Assessment patient outcomes; Continental population groups; Risk factors; Transplantation

Indexed keywords

ADULT; AFRICAN AMERICAN; AGED; ARTICLE; CAUCASIAN; FEMALE; HAZARD RATIO; HEART TRANSPLANTATION; HISPANIC; HUMAN; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RACE DIFFERENCE; RISK FACTOR; SURVIVAL; TREATMENT OUTCOME; UNITED STATES; ADOLESCENT; CHI SQUARE DISTRIBUTION; COMPARATIVE STUDY; ETHNOLOGY; GRAFT REJECTION; GRAFT SURVIVAL; HEALTH CARE SURVEY; HEALTH DISPARITY; KAPLAN MEIER METHOD; MIDDLE AGED; MORTALITY; PROPORTIONAL HAZARDS MODEL; RETROSPECTIVE STUDY; RISK ASSESSMENT; STATISTICS; SURVIVAL RATE; TIME;

IMMUNOSUPPRESSIVE AGENT;

ADOLESCENT; ADULT; AFRICAN AMERICANS; CHI-SQUARE DISTRIBUTION; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GRAFT REJECTION; GRAFT SURVIVAL; HEALTH CARE SURVEYS; HEALTH STATUS DISPARITIES; HEART TRANSPLANTATION; HISPANIC AMERICANS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; KAPLAN-MEIER ESTIMATE; MALE; MIDDLE AGED; PROPORTIONAL HAZARDS MODELS; RETROSPECTIVE STUDIES; RISK ASSESSMENT; RISK FACTORS; SURVIVAL RATE; TIME FACTORS; TREATMENT OUTCOME; UNITED STATES; YOUNG ADULT;

EID: 79955941172     PISSN: 19413289     EISSN: 19413297     Source Type: Journal    
DOI: 10.1161/CIRCHEARTFAILURE.110.957829     Document Type: Article

References (30)

1. Taylor DO, Edwards LB, Aurora P, Christie JD, Dobbels F, Kirk R, Rahmel AO, Kucheryavaya AY, Hertz MI. Registry of the International Society for Heart and Lung Transplantation: Twenty-fifth official adult heart transplant report-2008. J Heart Lung Transplant. 2008;27: 943-956.
2. Taylor DO, Stehlik J, Edwards LB, Aurora P, Christie JD, Dobbels F, Kirk R, Kucheryavaya AY, Rahmel AO, Hertz MI. Registry of the International Society for Heart and Lung Transplantation: Twenty-sixth official adult heart transplant report-2009. J Heart Lung Transplant. 2009;28:1007-1022.
3. Marelli D, Laks H, Kobashigawa JA, Bresson J, Ardehali A, Esmailian F, Plunkett MD, Kubak B. Seventeen-year experience with 1,083 heart transplants at a single institution. Ann Thorac Surg. 2002;74:1558-1566.
4. John R, Rajasinghe HA, Chen JM, Weinberg AD, Sinha P, Mancini DM, Naka Y, Oz MC, Smith CR, Rose EA, Edwards NM. Long-term outcomes after cardiac transplantation: An experience based on different eras of immunosuppressive therapy. Ann Thorac Surg. 2001;72:440-449. (Pubitemid 32727143)
5. Kofler S, Bigdeli AK, Kaczmarek I, Kellerer D, Muller T, Schmoeckel M, Steinbeck G, Uberfuhr P, Reichart B, Meiser B. Long-term outcomes after 1000 heart transplantations in six different eras of innovation in a single center. Transpl Int. 2009;22:1140-1150.
6. Cohen O, De La Zerda D, Beygui RE, Hekmat D, Laks H. Ethnicity as a predictor of graft longevity and recipient mortality in heart transplantation. Transplant Proc. 2007;39:3297-3302. (Pubitemid 350251467)
7. Mills RM, Naftel DC, Kirklin JK, Van Bakel AB, Jaski BE, Massin EK, Eisen HJ, Lee FA, Fishbein DP, Bourge RC. Heart transplant rejection with hemodynamic compromise: A multiinstitutional study of the role of endomyocardial cellular infiltrate. Cardiac Transplant Research Database. J Heart Lung Transplant. 1997;16:813-821. (Pubitemid 27362681)
8. Park MH, Tolman DE, Kimball PM. Disproportionate HLA matching may contribute to racial disparity in patient survival following cardiac transplantation. Clin Transplant. 1996;10:625-628. (Pubitemid 27010913)
9. Valente JF, Hariharan S, Peddi VR, Schroeder TJ, Ogle CK, Alexander JW, First MR. Causes of renal allograft loss in black vs. white transplant recipients in the cyclosporine era. Clin Transplant. 1997;11:231-236. (Pubitemid 27230803)
10. Mahle WT, Kanter KR, Vincent RN. Disparities in outcome for blafor black patients after pediatric heart transplantation. J Pediatr. 2005;147:739-743. (Pubitemid 41774827)
11. Costanzo MR, Naftel DC, Pritzker MR, Heilman JK III, Boehmer JP, Brozena SC, Dec GW, Ventura HO, Kirklin JK, Bourge RC, Miller LW. Heart transplant coronary artery disease detected by coronary angiography: A multiinstitutional study of preoperative donor and recipient risk factors. Cardiac Transplant Research Database. J Heart Lung Transplant. 1998;17:744-753. (Pubitemid 28396983)
12. Allen JG, Weiss ES, Arnaoutakis GJ, Russell SD, Baumgartner WA, Conte JV, Shah AS. The impact of race on survival after heart transplantation: An analysis of more than 20,000 patients. Ann Thorac Surg. 2010;89:1956 -1963.
13. Park MH, Tolman DE, Kimball PM. The impact of race and HLA matching on long-term survival following cardiac transplantation. Transplant Proc. 1997;29:1460-1463. (Pubitemid 27126271)
14. Girnita DM, Webber SA, Ferrell R, Burckart GJ, Brooks MM, McDade KK, Chinnock R, Canter C, Addonizio L, Bernstein D, Kirklin JK, Girnita AL, Zeevi A. Disparate distribution of 16 candidate single nucleotide polymorphisms among racial and ethnic groups of pediatric heart transplant patients. Transplantation. 2006;82:1774-1780. (Pubitemid 46035666)
15. Singh TP, Givertz MM, Semigran M, Denofrio D, Costantino F, Gauvreau K. Socioeconomic position, ethnicity, and outcomes in heart transplant recipients. Am J Cardiol. 2010;105:1024-1029.
16. Singh TP, Gauvreau K, Bastardi HJ, Blume ED, Mayer JE. Socioeconomic position and graft failure in pediatric heart transplant recipients. Circ Heart Fail. 2009;2:160-165.
17. Stephens MR, Evans M, Ilham MA, Marsden A, Asderakis A. The influence of socioeconomic deprivation on outcomes following renal transplantation in the United Kingdom. Am J Transplant. 2010;10:1605-1612.
18. Hutchings A, Purcell WM, Benfield MR. Increased costimulatory responses in African-American kidney allograft recipients. Transplantation. 2001;71: 692-695. (Pubitemid 32268075)
19. Gordon EJ, Ladner DP, Caicedo JC, Franklin J. Disparities in kidney transplant outcomes: A review. Semin Nephrol. 2010;30:81-89.
20. Kobashigawa JA, Meiser BM. Review of major clinical trials with mycophenolate mofetil in cardiac transplantation. Transplantation. 2005;80: S235-S243. (Pubitemid 41552910)
21. Kobashigawa JA, Miller LW, Russell SD, Ewald GA, Zucker MJ, Goldberg LR, Eisen HJ, Salm K, Tolzman D, Gao J, Fitzsimmons W, First R. Tacrolimus with mycophenolate mofetil (MMF) or sirolimus vs. cyclosporine with MMF in cardiac transplant patients: 1-year report. Am J Transplant. 2006;6:1377-1386. (Pubitemid 44030320)
22. Mancini D, Pinney S, Burkhoff D, LaManca J, Itescu S, Burke E, Edwards N, Oz M, Marks AR. Use of rapamycin slows progression of cardiac transplantation vasculopathy. Circulation. 2003;108:48-53. (Pubitemid 36859019)
23. Kobashigawa JA, Katznelson S, Laks H, Johnson JA, Yeatman L, Wang XM, Chia D, Terasaki PI, Sabad A, Cogert GA, Trosian K, Hamilton MA, Moriguchi JD, Kawata N, Hage A, Drinkwater DC, Stevenson LW. Effect of pravastatin on outcomes after cardiac transplantation. N Engl J Med. 1995;333:621-627.
24. Oliver JD III, Neff RT, Leeser DB, Swanson SJ, Yuan CM, Falta EM, Elster E, Reinmuth B, Bohen EM, Jindal RM, Abbott KC. Influence of race on kidney transplantation in the Department of Defense healthcare system. Am J Nephrol. 2009;29:327-333.
25. Schlotthauer AE, Badler A, Cook SC, Perez DJ, Chin MH. Evaluating interventions to reduce health care disparities: An RWJF program. Health Aff (Millwood). 2008;27:568-573. (Pubitemid 351490349)
26. Bibbins-Domingo K, Pletcher MJ, Lin F, Vittinghoff E, Gardin JM, Arynchyn A, Lewis CE, Williams OD, Hulley SB. Racial differences in incident heart failure among young adults. N Engl J Med. 2009;360: 1179-1190.
27. Mensah GA, Mokdad AH, Ford ES, Greenlund KJ, Croft JB. State of disparities in cardiovascular health in the United States. Circulation. 2005;111:1233-1241. (Pubitemid 40389086)
28. Rose G. Strategy of prevention: Lessons from cardiovascular disease. BMJ (Clin Res Ed). 1981;282:1847-1851. (Pubitemid 11047749)
29. Nelson AR. Unequal treatment: Report of the Institute of Medicine on racial and ethnic disparities in healthcare. Ann Thorac Surg. 2003;76: S1377-S1381. (Pubitemid 37204781)
30. Chin MH, Walters AE, Cook SC, Huang ES. Interventions to reduce racial and ethnic disparities in health care. Med Care Res Rev. 2007;64:7S-28S. (Pubitemid 47459675)