-
1
-
-
79955399340
-
Definition and classification of cancer cachexia: An international consensus
-
Fearon K, Strasser F, Anker SD, et al. Definition and classification of cancer cachexia: an international consensus. Lancet Oncol. 2011; 12:489-495.
-
(2011)
Lancet Oncol
, vol.12
, pp. 489-495
-
-
Fearon, K.1
Strasser, F.2
Anker, S.D.3
-
2
-
-
84864646651
-
Cancer cachexia: Mediators, signaling, and metabolic pathways
-
Fearon KC, Glass DJ, Guttridge DC. Cancer cachexia: mediators, signaling, and metabolic pathways. Cell Metab. 2012;16:153-166.
-
(2012)
Cell Metab
, vol.16
, pp. 153-166
-
-
Fearon, K.C.1
Glass, D.J.2
Guttridge, D.C.3
-
3
-
-
65249138226
-
Sarcopenia as a determinant of chemotherapy toxicity and time to tumor progression in metastatic breast cancer patients receiving capecitabine treatment
-
Prado CM, Baracos VE, McCargar LJ, et al. Sarcopenia as a determinant of chemotherapy toxicity and time to tumor progression in metastatic breast cancer patients receiving capecitabine treatment. Clin Cancer Res. 2009;15:2920-2926.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 2920-2926
-
-
Prado, C.M.1
Baracos, V.E.2
McCargar, L.J.3
-
4
-
-
84855318187
-
Body composition, symptoms, and survival in advanced cancer patients referred to a phase I service
-
Parsons HA, Baracos VE, Dhillon N, Hong DS, Kurzrock R. Body composition, symptoms, and survival in advanced cancer patients referred to a phase I service. PLoS One. 2012;7:e29330.
-
(2012)
PLoS One
, vol.7
, pp. e29330
-
-
Parsons, H.A.1
Baracos, V.E.2
Dhillon, N.3
Hong, D.S.4
Kurzrock, R.5
-
5
-
-
67650717476
-
The biology of activin: Recent advances in structure, regulation and function
-
Xia Y, Schneyer AL. The biology of activin: recent advances in structure, regulation and function. J Endocrinol. 2009;202:1-12.
-
(2009)
J Endocrinol
, vol.202
, pp. 1-12
-
-
Xia, Y.1
Schneyer, A.L.2
-
6
-
-
0038237434
-
Serum concentrations of activin and follistatin are elevated and run in parallel in patients with septicemia
-
Michel U, Ebert S, Phillips D, Nau R. Serum concentrations of activin and follistatin are elevated and run in parallel in patients with septicemia. Eur J Endocrinol. 2003;148:559-564.
-
(2003)
Eur J Endocrinol
, vol.148
, pp. 559-564
-
-
Michel, U.1
Ebert, S.2
Phillips, D.3
Nau, R.4
-
7
-
-
84881257262
-
The activins and their binding protein, follistatin-Diagnostic and therapeutic targets in inflammatory disease and fibrosis
-
Hedger MP, de Kretser DM. The activins and their binding protein, follistatin-Diagnostic and therapeutic targets in inflammatory disease and fibrosis. Cytokine Growth Factor Rev. 2013;24:285-295.
-
(2013)
Cytokine Growth Factor Rev
, vol.24
, pp. 285-295
-
-
Hedger, M.P.1
De Kretser, D.M.2
-
8
-
-
84886735949
-
Serum activin A and B levels predict outcome in patients with acute respiratory failure: A prospective cohort study
-
de Kretser DM, Bensley JG, Pettila V, et al. Serum activin A and B levels predict outcome in patients with acute respiratory failure: a prospective cohort study. Crit Care. 2013;17:R263.
-
(2013)
Crit Care
, vol.17
, pp. R263
-
-
De Kretser, D.M.1
Bensley, J.G.2
Pettila, V.3
-
9
-
-
0029950962
-
Serum immunoreactive activin A levels in normal subjects and patients with various diseases
-
Harada K, Shintani Y, Sakamoto Y, Wakatsuki M, Shitsukawa K, Saito S. Serum immunoreactive activin A levels in normal subjects and patients with various diseases. J Clin Endocrinol Metab. 1996; 81:2125-2130.
-
(1996)
J Clin Endocrinol Metab
, vol.81
, pp. 2125-2130
-
-
Harada, K.1
Shintani, Y.2
Sakamoto, Y.3
Wakatsuki, M.4
Shitsukawa, K.5
Saito, S.6
-
10
-
-
33748954261
-
Activin A circulating levels in patients with bone metastasis from breast or prostate cancer
-
Leto G, Incorvaia L, Badalamenti G, et al. Activin A circulating levels in patients with bone metastasis from breast or prostate cancer. Clin Exp Metastasis. 2006;23:117-122.
-
(2006)
Clin Exp Metastasis
, vol.23
, pp. 117-122
-
-
Leto, G.1
Incorvaia, L.2
Badalamenti, G.3
-
11
-
-
0031010050
-
Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member
-
McPherron AC, Lawler AM, Lee SJ. Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member. Nature. 1997;387:83-90.
-
(1997)
Nature
, vol.387
, pp. 83-90
-
-
McPherron, A.C.1
Lawler, A.M.2
Lee, S.J.3
-
13
-
-
77955642517
-
Reversal of cancer cachexia and muscle wasting by ActRIIB antagonism leads to prolonged survival
-
Zhou X, Wang JL, Lu J, et al. Reversal of cancer cachexia and muscle wasting by ActRIIB antagonism leads to prolonged survival. Cell. 2010;142:531-543.
-
(2010)
Cell
, vol.142
, pp. 531-543
-
-
Zhou, X.1
Wang, J.L.2
Lu, J.3
-
14
-
-
84901010269
-
Elevated expression of activins promotes muscle wasting and cachexia
-
Chen JL, Walton KL, Winbanks CE, et al. Elevated expression of activins promotes muscle wasting and cachexia. FASEB J. 2014;28: 1711-1723.
-
(2014)
FASEB J
, vol.28
, pp. 1711-1723
-
-
Chen, J.L.1
Walton, K.L.2
Winbanks, C.E.3
-
15
-
-
67650071006
-
Follistatin induces muscle hypertrophy through satellite cell proliferation and inhibition of both myostatin and activin
-
Gilson H, Schakman O, Kalista S, Lause P, Tsuchida K, Thissen JP. Follistatin induces muscle hypertrophy through satellite cell proliferation and inhibition of both myostatin and activin. Am J Physiol Endocrinol Metab. 2009;297:E157-164.
-
(2009)
Am J Physiol Endocrinol Metab
, vol.297
, pp. E157-E164
-
-
Gilson, H.1
Schakman, O.2
Kalista, S.3
Lause, P.4
Tsuchida, K.5
Thissen, J.P.6
-
16
-
-
34347223985
-
Ectopic expression of myostatin induces atrophy of adult skeletal muscle by decreasing muscle gene expression
-
Durieux AC, Amirouche A, Banzet S, et al. Ectopic expression of myostatin induces atrophy of adult skeletal muscle by decreasing muscle gene expression. Endocrinology. 2007;148:3140-3147.
-
(2007)
Endocrinology
, vol.148
, pp. 3140-3147
-
-
Durieux, A.C.1
Amirouche, A.2
Banzet, S.3
-
17
-
-
0037165983
-
Induction of cachexia in mice by systemically administered myostatin
-
Zimmers TA, Davies MV, Koniaris LG, et al. Induction of cachexia in mice by systemically administered myostatin. Science. 2002;296: 1486-1488.
-
(2002)
Science
, vol.296
, pp. 1486-1488
-
-
Zimmers, T.A.1
Davies, M.V.2
Koniaris, L.G.3
-
18
-
-
84866527529
-
Myostatin blockage using actRIIB antagonism in mice bearing the Lewis lung carcinoma results in the improvement of muscle wasting and physical performance
-
Busquets S, Toledo M, Orpí M, et al. Myostatin blockage using actRIIB antagonism in mice bearing the Lewis lung carcinoma results in the improvement of muscle wasting and physical performance. J Cachexia Sarcopenia Muscle. 2012;3:37-43.
-
(2012)
J Cachexia Sarcopenia Muscle
, vol.3
, pp. 37-43
-
-
Busquets, S.1
Toledo, M.2
Orpí, M.3
-
19
-
-
13044265837
-
Organization of the human myostatin gene and expression in healthy men and HIV-infected men with muscle wasting
-
Gonzalez-Cadavid NF, Taylor WE, Yarasheski K, et al. Organization of the human myostatin gene and expression in healthy men and HIV-infected men with muscle wasting. Proc Natl Acad Sci USA. 1998;95:14938-14943.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 14938-14943
-
-
Gonzalez-Cadavid, N.F.1
Taylor, W.E.2
Yarasheski, K.3
-
20
-
-
0036959537
-
Serum myostatin-immunoreactive protein is increased in 60-92 year old women and men with muscle wasting
-
Yarasheski KE, Bhasin S, Sinha-Hikim I, Pak-Loduca J, Gonzalez-Cadavid NF. Serum myostatin-immunoreactive protein is increased in 60-92 year old women and men with muscle wasting. J Nutr Health Aging. 2002;6:343-348.
-
(2002)
J Nutr Health Aging
, vol.6
, pp. 343-348
-
-
Yarasheski, K.E.1
Bhasin, S.2
Sinha-Hikim, I.3
Pak-Loduca, J.4
Gonzalez-Cadavid, N.F.5
-
22
-
-
84894140559
-
Highly specific detection of myostatin prodomain by an immunoradiometric sandwich assay in serum of healthy individuals and patients
-
Breitbart A, Scharf GM, Duncker D, et al. Highly specific detection of myostatin prodomain by an immunoradiometric sandwich assay in serum of healthy individuals and patients. PLoS One. 2013;8:e80454.
-
(2013)
PLoS One
, vol.8
, pp. e80454
-
-
Breitbart, A.1
Scharf, G.M.2
Duncker, D.3
-
23
-
-
84864762337
-
Myostatin is a novel tumoral factor that induces cancer cachexia
-
Lokireddy S, Wijesoma IW, Bonala S, et al. Myostatin is a novel tumoral factor that induces cancer cachexia. Biochem J. 2012;446: 23-36.
-
(2012)
Biochem J
, vol.446
, pp. 23-36
-
-
Lokireddy, S.1
Wijesoma, I.W.2
Bonala, S.3
-
24
-
-
32944468790
-
Appetite assessment: Simple appetite questionnaire predicts weight loss in community-dwelling adults and nursing home residents
-
Wilson MM, Thomas DR, Rubenstein LZ, et al. Appetite assessment: simple appetite questionnaire predicts weight loss in community-dwelling adults and nursing home residents. Am J Clin Nutr. 2005;82:1074-1081.
-
(2005)
Am J Clin Nutr
, vol.82
, pp. 1074-1081
-
-
Wilson, M.M.1
Thomas, D.R.2
Rubenstein, L.Z.3
-
25
-
-
58949096799
-
A systematic review of the scales used for the measurement of cancer-related fatigue (CRF)
-
Minton O, Stone P. A systematic review of the scales used for the measurement of cancer-related fatigue (CRF). Ann Oncol. 2009; 20:17-25.
-
(2009)
Ann Oncol
, vol.20
, pp. 17-25
-
-
Minton, O.1
Stone, P.2
-
26
-
-
53649107585
-
A practical and precise approach to quantification of body composition in cancer patients using computed tomography images acquired during routine care
-
Mourtzakis M, Prado CM, Lieffers JR, Reiman T, McCargar LJ, Baracos VE. A practical and precise approach to quantification of body composition in cancer patients using computed tomography images acquired during routine care. Appl Physiol Nutr Metab. 2008;33:997-1006.
-
(2008)
Appl Physiol Nutr Metab
, vol.33
, pp. 997-1006
-
-
Mourtzakis, M.1
Prado, C.M.2
Lieffers, J.R.3
Reiman, T.4
McCargar, L.J.5
Baracos, V.E.6
-
27
-
-
84893458950
-
Measurement of skeletal muscle radiation attenuation and basis of its biological variation
-
Aubrey J, Esfandiari N, Baracos VE, et al. Measurement of skeletal muscle radiation attenuation and basis of its biological variation. Acta Physiol (Oxf). 2014;210:489-497.
-
(2014)
Acta Physiol (Oxf)
, vol.210
, pp. 489-497
-
-
Aubrey, J.1
Esfandiari, N.2
Baracos, V.E.3
-
28
-
-
0006728596
-
-
New York, NY: Oxford University Press Inc.
-
Gibson RS. Nutritional Assessment. New York, NY: Oxford University Press Inc.; 1993.
-
(1993)
Nutritional Assessment
-
-
Gibson, R.S.1
-
29
-
-
0036175293
-
Impedance vector distribution by sex, race, body mass index, and age in the United States: Standard reference intervals as bivariate Z scores
-
Piccoli A, Pillon L, Dumler F. Impedance vector distribution by sex, race, body mass index, and age in the United States: standard reference intervals as bivariate Z scores. Nutrition. 2002;18:153-167.
-
(2002)
Nutrition
, vol.18
, pp. 153-167
-
-
Piccoli, A.1
Pillon, L.2
Dumler, F.3
-
30
-
-
0033912816
-
Skeletal muscle attenuation determined by computed tomography is associated with skeletal muscle lipid content
-
Goodpaster BH, Kelley DE, Thaete FL, He J, Ross R. Skeletal muscle attenuation determined by computed tomography is associated with skeletal muscle lipid content. J Appl Physiol. 2000;89:104-110.
-
(2000)
J Appl Physiol
, vol.89
, pp. 104-110
-
-
Goodpaster, B.H.1
Kelley, D.E.2
Thaete, F.L.3
He, J.4
Ross, R.5
-
31
-
-
84867135322
-
Circulating activin-A is elevated in patients with advanced multiple myeloma and correlates with extensive bone involvement and inferior survival; no alterations post-lenalidomide and dexamethasone therapy
-
Terpos E, Kastritis E, Christoulas D, et al. Circulating activin-A is elevated in patients with advanced multiple myeloma and correlates with extensive bone involvement and inferior survival; no alterations post-lenalidomide and dexamethasone therapy. Ann Oncol. 2012;23:2681-2686.
-
(2012)
Ann Oncol
, vol.23
, pp. 2681-2686
-
-
Terpos, E.1
Kastritis, E.2
Christoulas, D.3
-
32
-
-
84862502202
-
Changes in myostatin signaling in non-weight-losing cancer patients
-
Aversa Z, Bonetto A, Penna F, et al. Changes in myostatin signaling in non-weight-losing cancer patients. Ann Surg Oncol. 2012;19: 1350-1356.
-
(2012)
Ann Surg Oncol
, vol.19
, pp. 1350-1356
-
-
Aversa, Z.1
Bonetto, A.2
Penna, F.3
-
33
-
-
84896771237
-
Clinical classification of cancer cachexia: Phenotypic correlates in human skeletal muscle
-
Johns N, Hatakeyama S, Stephens NA, et al. Clinical classification of cancer cachexia: phenotypic correlates in human skeletal muscle. PLoS One. 2014;9:e83618.
-
(2014)
PLoS One
, vol.9
, pp. e83618
-
-
Johns, N.1
Hatakeyama, S.2
Stephens, N.A.3
-
34
-
-
84862885577
-
Intramyocellular lipid droplets increase with progression of cachexia in cancer patients
-
Stephens NA, Skipworth RJ, Macdonald AJ, Greig CA, Ross JA, Fearon KC. Intramyocellular lipid droplets increase with progression of cachexia in cancer patients. J Cachexia Sarcopenia Muscle. 2011;2:111-117.
-
(2011)
J Cachexia Sarcopenia Muscle
, vol.2
, pp. 111-117
-
-
Stephens, N.A.1
Skipworth, R.J.2
Macdonald, A.J.3
Greig, C.A.4
Ross, J.A.5
Fearon, K.C.6
-
35
-
-
84883565044
-
Skeletal muscle density predicts prognosis in patients with metastatic renal cell carcinoma treated with targeted therapies
-
Antoun S, Lanoy E, Iacovelli R, et al. Skeletal muscle density predicts prognosis in patients with metastatic renal cell carcinoma treated with targeted therapies. Cancer. 2013;119:3377-3384.
-
(2013)
Cancer
, vol.119
, pp. 3377-3384
-
-
Antoun, S.1
Lanoy, E.2
Iacovelli, R.3
-
36
-
-
36049023174
-
Activin A is a critical component of the inflammatory response, and its binding protein, follistatin, reduces mortality in endotoxemia
-
Jones KL, Mansell A, Patella S, et al. Activin A is a critical component of the inflammatory response, and its binding protein, follistatin, reduces mortality in endotoxemia. Proc Natl Acad Sci U S A. 2007; 104:16239-16244.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 16239-16244
-
-
Jones, K.L.1
Mansell, A.2
Patella, S.3
-
37
-
-
0030018821
-
The relationship between weight loss and interleukin 6 in non-small-cell lung cancer
-
Scott HR, McMillan DC, Crilly A, McArdle CS, Milroy R. The relationship between weight loss and interleukin 6 in non-small-cell lung cancer. Br J Cancer. 1996;73:1560-1562.
-
(1996)
Br J Cancer
, vol.73
, pp. 1560-1562
-
-
Scott, H.R.1
McMillan, D.C.2
Crilly, A.3
McArdle, C.S.4
Milroy, R.5
-
38
-
-
67449088926
-
Pro-inflammatory cytokine release by peripheral blood mononuclear cells from patients with advanced pancreatic cancer: Relationship to acute phase response and survival
-
Moses AG, Maingay J, Sangster K, Fearon KC, Ross JA. Pro-inflammatory cytokine release by peripheral blood mononuclear cells from patients with advanced pancreatic cancer: relationship to acute phase response and survival. Oncol Rep. 2009;21:1091-1095.
-
(2009)
Oncol Rep
, vol.21
, pp. 1091-1095
-
-
Moses, A.G.1
Maingay, J.2
Sangster, K.3
Fearon, K.C.4
Ross, J.A.5
-
39
-
-
84856229722
-
Is IL-6 the best pro-inflammatory biomarker of clinical outcomes of cancer cachexia?
-
Scheede-Bergdahl C, Watt HL, Trutschnigg B, et al. Is IL-6 the best pro-inflammatory biomarker of clinical outcomes of cancer cachexia? Clin Nutr. 2012;31:85-88.
-
(2012)
Clin Nutr
, vol.31
, pp. 85-88
-
-
Scheede-Bergdahl, C.1
Watt, H.L.2
Trutschnigg, B.3
-
40
-
-
77950459905
-
A placebo-controlled, double-blind trial of infliximab for cancer-associated weight loss in elderly and/or poor performance non-small cell lung cancer patients (N01C9)
-
Jatoi A, Ritter HL, Dueck A, et al. A placebo-controlled, double-blind trial of infliximab for cancer-associated weight loss in elderly and/or poor performance non-small cell lung cancer patients (N01C9). Lung Cancer. 2010;68:234-239.
-
(2010)
Lung Cancer
, vol.68
, pp. 234-239
-
-
Jatoi, A.1
Ritter, H.L.2
Dueck, A.3
-
41
-
-
80555127351
-
A humanized anti-IL-6 antibody (ALD518) in non-small cell lung cancer
-
Bayliss TJ, Smith JT, Schuster M, Dragnev KH, Rigas JR. A humanized anti-IL-6 antibody (ALD518) in non-small cell lung cancer. Expert Opin Biol Ther. 2011;11:1663-1668.
-
(2011)
Expert Opin Biol Ther
, vol.11
, pp. 1663-1668
-
-
Bayliss, T.J.1
Smith, J.T.2
Schuster, M.3
Dragnev, K.H.4
Rigas, J.R.5
-
42
-
-
27644555549
-
Myostatin, the cardiac chalone of insulin-like growth factor-1
-
Gaussin V, Depre C. Myostatin, the cardiac chalone of insulin-like growth factor-1. Cardiovasc Res. 2005;68:347-349.
-
(2005)
Cardiovasc Res
, vol.68
, pp. 347-349
-
-
Gaussin, V.1
Depre, C.2
-
43
-
-
45149105837
-
Muscle myostatin signalling is enhanced in experimental cancer cachexia
-
Costelli P, Muscaritoli M, Bonetto A, et al. Muscle myostatin signalling is enhanced in experimental cancer cachexia. Eur J Clin Invest. 2008;38:531-538.
-
(2008)
Eur J Clin Invest
, vol.38
, pp. 531-538
-
-
Costelli, P.1
Muscaritoli, M.2
Bonetto, A.3
|