Predicting essential genes and synthetic lethality via influence propagation in signaling pathways of cancer cell fates

Journal of Bioinformatics and Computational Biology

Volumn 13, Issue 3, 2015, Pages

  Zhang, Fan ^a   Wu, Min ^b   Li, Xue Juan ^a   Li, Xiao Li ^b   Kwoh, Chee Keong ^a   Zheng, Jie ^a,c  

^a NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^b INSTITUTE FOR INFOCOMM RESEARCH   (Singapore)

^c GENOME INSTITUTE OF SINGAPORE   (Singapore)

Author keywords

data driven; signaling pathways; Synthetic lethality

Indexed keywords

ALGORITHM; BIOLOGICAL MODEL; CELL DEATH; COMPUTER SIMULATION; ESSENTIAL GENE; GENE SILENCING; GENETICS; HUMAN; NEOPLASM; PATHOLOGY; PERSONALIZED MEDICINE; PROCEDURES; SIGNAL TRANSDUCTION;

ALGORITHMS; CELL DEATH; COMPUTER SIMULATION; GENE KNOCKDOWN TECHNIQUES; GENES, ESSENTIAL; HUMANS; MODELS, GENETIC; NEOPLASMS; PRECISION MEDICINE; SIGNAL TRANSDUCTION;

EID: 84929340603     PISSN: 02197200     EISSN: 17576334     Source Type: Journal    
DOI: 10.1142/S0219720015410024     Document Type: Conference Paper

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