Detection of early cartilage damage using targeted nanosomes in a post-traumatic osteoarthritis mouse model

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 11, Issue 4, 2015, Pages 939-946

  Cho, Hongsik ^a   Pinkhassik, Eugene ^d   David, Valentin ^c   Stuart, John M ^b   Hasty, Karen A ^a,b  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c NORTHWESTERN UNIVERSITY   (United States)

^d UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

Extracelluar matrix (ECM); Monoclonal antibody (Mab); Nanosomes (nano size of liposome); Near infrared fluorescent (NIF); Osteoarthritis (OA); Post traumatic osteoarthritis (PTOA); Theranostic (therapeutic and diagnostic); Type II collagen (CII)

Indexed keywords

AUTOMOBILE DRIVERS; CARTILAGE; COLLAGEN; CONTROLLED DRUG DELIVERY; DIAGNOSIS; FLUORESCENCE IMAGING; INFRARED DEVICES; MAMMALS; MONOCLONAL ANTIBODIES; TARGETED DRUG DELIVERY; THERANOSTICS;

EXTRACELLUAR MATRIXES; MONOCLONAL ANTIBODIES (MAB); NANO-SIZE; NEAR-INFRARED FLUORESCENT; OSTEOARTHRITIS (OA); POST-TRAUMATIC OSTEOARTHRITIS; THERANOSTIC (THERAPEUTIC AND DIAGNOSTIC); TYPE II COLLAGENS;

DAMAGE DETECTION;

COLLAGEN TYPE 2; COLLAGENASE 3; FLUORESCENT DYE; TUMOR NECROSIS FACTOR ALPHA; ANTIBODY; NANOPARTICLE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARTILAGE INJURY; CONTROLLED STUDY; DISEASE COURSE; FLUORESCENCE IMAGING; GENE EXPRESSION; HISTOPATHOLOGY; KNEE INJURY; MALE; MOUSE; NONHUMAN; OSTEOARTHRITIS; POST TRAUMATIC OSTEOARTHRITIS; UPREGULATION; ANIMAL; CARTILAGE; CHEMISTRY; COMPLICATION; DISEASE MODEL; HUMAN; INJURIES; METABOLISM; OSTEOARTHRITIS, KNEE; PATHOLOGY; PROCEDURES;

MUS;

ANIMALS; ANTIBODIES; CARTILAGE; COLLAGEN TYPE II; DISEASE MODELS, ANIMAL; HUMANS; KNEE INJURIES; MICE; NANOPARTICLES; OPTICAL IMAGING; OSTEOARTHRITIS, KNEE;

EID: 84929324808     PISSN: 15499634     EISSN: 15499642     Source Type: Journal    
DOI: 10.1016/j.nano.2015.01.011     Document Type: Article

References (41)

1. Felson D.T., Lawrence R.C., Dieppe P.A., et al. Osteoarthritis: new insights. Part 1: the disease and its risk factors. Ann Intern Med 2000, 133:635-646.
2. Stolz M., Gottardi R., Raiteri R., Miot S., Martin I., Imer R., et al. Early detection of aging cartilage and osteoarthritis in mice and patient samples using atomic force microscopy. Nat Nanotechnol 2009, 4:186-192.
3. Anderson D., Chubinskaya S., Guilak F., Martin J.A., Oegema T.R., Olson S.A., et al. Post-traumatic osteoarthritis: improved understanding and opportunities for early intervention. J Orthop Res 2011, 29:802-809.
4. Lotz M.K. Posttraumatic osteoarthritis: pathogenesis and pharmacological treatment options. Arthritis Res Ther 2010, 12:211-220.
5. Kramer W.C., Hendricks K.J., Wang J. Pathogenetic mechanisms of posttraumatic osteoarthritis: opportunities for early intervention. Int J Clin Exp Med 2011, 4(4):285-298.
6. Martin J.A., Brown T., Heiner A., Buckwalter J.A. Post-traumatic osteoarthritis: the role of accelerated chondrocyte senescence. Biorheology 2004, 41:479-491.
7. von Porat A., Roos E.M., Roos H. High prevalence of osteoarthritis 14 years after anterior cruciate ligament tear in male soccer players: a study of radiographic and patient relevant outcomes. Ann Rheum Dis 2004, 63:269-273.
8. Lohmander L.S., Englund P.M., Dahl L.L., Roos E.M. The long-term consequence of anterior cruciate ligament and meniscus injuries. Am J Sports Med 2007, 35:1756-1769.
9. Anderson D.D., Marsh J.L., Brown T.D. The pathomechanical etiology of post-traumatic osteoarthritis following intraarticular fractures. Iowa Orthop J 2011, 31:1-20.
10. Christiansen B.A., Lee C.A., Anderson M.J., Williams J.C., Yik J., Haudenschild D.R. Musculoskeletal changes following non-invasive knee injury using a novel mouse model of post-traumatic osteoarthritis. Osteoarthr Cartil 2012, 20:773-782.
11. Poulet B., Hamilton R.W., Shefelbine S., Pitsillides A.A. Characterizing a novel and adjustable noninvasive murine joint loading model. Arthritis Rheum 2011, 63(1):13-47.
12. Hollander A.P., Heathfield T.F., Webber C., Iwata Y., Boume R., Rorabeck C., et al. Increased damage to type II collagen in osteoarthritic articular cartilage detected by a new immunoassay. J Clin Invest 1994, 93:1722-1732.
13. Smith G.N. The role of collagenolytic matrix metalloproteinases in the loss of articular cartilage in osteoarthritis. Front Biosci 2006, 11:3081-3095.
14. Karsdal M.A., Madsen S.H., Christiansen C., Henriksen K., Fosang A.J., Sondergaard B.C. Cartilage degradation is fully reversible in the presence of aggrecanase but not matrix metalloproteinase activity. Arthritis Res Ther 2008, 10:1-12. [R63].
15. Homandberg G.A., Hui F., Wen C., Purple C., Bewsey K., Koepp H., et al. Fibronectin-fragment-induced cartilage chondrolysis is associated with release of catabolic cytokines. Biochem J 1997, 321(Pt 3):751-757.
16. Jasin H.E., Taurog J.D. Mechanisms of disruption of articular cartilage surface in inflammation. J Clin Investig 1991, 87:1531-1536.
17. Jasin H.E., Noyori K., Takagi T., Taurog J.D. Characteristics of antitype II collagen antibody binding to articular cartilage. Arthritis Rheum 1993, 36:651-659.
18. Noyori K., Koshino T., Takagi T., Okamoto R., Jasin H.E. Binding characteristics of antitype II collagen antibody to the surface of diseased human cartilage as a probe for tissue damage. J Rheumatol 1994, 21:293-296.
19. Cho H., Stuart J., Magid R., Danila D.C., Pinkhassik E., Hasty K.A. Theranostic immunoliposomes for osteoarthritis. Nanomedicine: NBM 2014, 10(3):619-627.
20. Vasir Jaspreet K., Reddy Maram K., Labhasetwar Vinod D. Nanosystems in drug targeting: opportunities and challenges. Curr Nanosci 2005, 1:47-64.
21. Torchilin V.P. Recent advances with liposomes as pharmaceutical carriers. Nat Rev 2005, 4:145-160.
22. Park S.H., Seth A., Lee S., Min B.H., Kim S.J., Hasty K.A., et al. Recent advances in liposome techniques and the applications in arthritis. Recent Pat Biomed Eng 2012, 5(1):57-62.
23. Huang J., Ballou L.R., Hasty K.A. Cyclic equibiaxial tensile strain induces both anabolic and catabolic responses in articular chondrocytes. Gene 2007, 404:101-109.
24. Overbergh L., Valckx D., Waer M., Mathieu C. Quantification of murine cytokine mRNAs using real time quantitative reverse transcriptase PCR. Cytokine 1999, 11:305-312.
25. Giulietti A., Overbergh L., Valckx D., Decallonne B., Bouillon R., Mathieu C. An overview of real-time quantitative PCR: applications to quantify cytokine gene expression. Methods 2001, 2:386-401.
26. Huwyler J., Wu D., Pardridge W.M. Brain drug delivery of small molecules using immunoliposomes. Proc Natl Acad Sci 1996, 93:14164-14169.
27. Rongen H.A.H., Bult A., van Bennekom W.P. Liposomes and immunoassays. J Immunol Methods 1997, 204(2):105-133.
28. Terato K., Hasty K.A., Reife R.A., Cremer M.A., Kang A.H., Stuart J.M. Induction of arthritis with monoclonal antibodies to collagen. J Immunol 1992, 148(7):2103-2108.
29. Glasson S.S., Chambers M.G., Van Den Berg W.B., Little C.B. The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the mouse. Osteoarthritis Cartilage 2010, 18(3):S17-S23.
30. van Osch G.J., van der Kraan P.M., Blankevoort L., Huiskes R., van den Berg W.B. Relation of ligament damage with site specific cartilage loss and osteophyte formation in collagenase induced osteoarthritis in mice. J Rheumatol 1996, 23(7):1227-1232.
31. Joosten L.A., Smeets R.L., Koenders M.I., van den Bersselaar L.A., Helsen M.M., Oppers-Walgreen B., et al. Interleukin-18 promotes joint inflammation and induces interleukin-1-driven cartilage destruction. Am J Pathol 2004, 165(3):959-967.
32. Clements K.M., Price J.S., Chambers M.G., Visco D.M., Poole A.R., Mason R.M. Gene deletion of either interleukin-1 beta, interleukin-1 beta converting enzyme, inductible nitric oxide sythetase, or stomelysin 1 accelerates the development of knee osteoarthritis in mice after surgical transection of the medial collateral ligament and partial medial meniscectomy. Arthritis Rheum 2003, 48(12):3452-3463.
33. Kamekura S., Hoshi K., Shimoaka T., Chung U., Chikuda H., Yamada T., et al. Osteoarthritis development in novel experimental mouse models induced by knee joint instability. Osteoarthritis Cartilage 2005, 13(7):632-641.
34. Glasson S.S., Blanchet T.J., Morris E.A. The surgical destabilization of the medial meniscus (DMM) model of osteoarthritis in the 129/SvEv mouse. Osteoarthritis Cartilage 2007, 15(9):1061-1069.
35. Pearle A.D., Warren R.F., Rodeo S.A. Basic science of articular cartilage and osteoarthritis. Clin Sports Med 2005, 24:1-12.
36. Sandell L.J., Aigner T. Articular cartilage and changes in arthritis. An introduction: cell biology of osteoarthritis. Arthritis Res Ther 2001, 3:107-113.
37. Pitsillides A., Beier F. Cartilage biology in osteoarthritis: lessons from developmental biology. Nat Rev Rheumatol 2011, 7:654-663.
38. Brandt K.D., Braunstein E.M., Visco D.M., O'Connor B., Heck D., Albrecht M. Anterior (cranial) cruciate ligament transection in the dog: a bona fide model of osteoarthritis, not merely of cartilage injury and repair. J Rheumatol 1991, 18(3):436-446.
39. Eyre D.R., McDevitt C.A., Billingham M.E.J., Muir H. Biosynthesis of collagen and other matrix proteins by articular cartilage in experimental osteoarthrosis. Biochem J 1980, 188:823-837.
40. Hollander A.P., Pidoux I., Reiner A., Rorabeck C., Bourne R., Poole R. Damage to type II collagen in aging and osteoarthritis starts at the articular surface, originates around chondrocytes, and extends into the cartilage with progressive degeneration. J Clin Invest 1995, 96:2859-2869.
41. Fosang A.J., Beier F. Emerging frontiers in cartilage and chondrocyte biology. Best Pract Res Clin Rheumatol 2011, 25(6):751-766.