Characterization of reward and effort mechanisms in apathy

Journal of Physiology Paris

Volumn 109, Issue 1-3, 2015, Pages 16-26

  Bonnelle, Valerie ^a   Veromann, Kai Riin ^a   Burnett Heyes, Stephanie ^a   Lo Sterzo, Elena ^a   Manohar, Sanjay ^a,b   Husain, Masud ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Action initiation; Apathy; Decision making; Effort discounting; Motivation

Indexed keywords

ADAPTIVE BEHAVIOR; ADULT; AGED; APATHY; ARTICLE; DECISION MAKING; FEEDBACK SYSTEM; FEMALE; HUMAN; HUMAN EXPERIMENT; IMPULSIVENESS; LILLE APATHY RATING SCALE; MALE; MOTIVATION; NEUROMODULATION; NORMAL HUMAN; PERCEPTIVE THRESHOLD; PHYSICAL CAPACITY; RATING SCALE; REWARD; STIMULUS RESPONSE; TASK PERFORMANCE; ADOLESCENT; ALGORITHM; ANALYSIS OF VARIANCE; MIDDLE AGED; PHYSIOLOGY; STATISTICS; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; ALGORITHMS; ANALYSIS OF VARIANCE; APATHY; DECISION MAKING; FEEDBACK, PSYCHOLOGICAL; FEMALE; HUMANS; MALE; MIDDLE AGED; MOTIVATION; REWARD; STATISTICS AS TOPIC; YOUNG ADULT;

EID: 84929324315     PISSN: 09284257     EISSN: 17697115     Source Type: Journal    
DOI: 10.1016/j.jphysparis.2014.04.002     Document Type: Article

References (34)

1. Adam R., Leff A., Sinha N., Turner C., Bays P., Draganski B., Husain M. Dopamine reverses reward insensitivity in apathy following globus pallidus lesions. Cortex J. Devoted Study Nerv. Syst. Behav. 2013, 49:1292-1303.
2. Bijleveld E., Custers R., Aarts H. Adaptive reward pursuit: how effort requirements affect unconscious reward responses and conscious reward decisions. J. Exp. Psychol. Gen. 2012, 141:728-742.
3. Botvinick M.M., Huffstetler S., McGuire J.T. Effort discounting in human nucleus accumbens. Cogn. Affect. Behav. Neurosci. 2009, 9:16-27.
4. Brodaty H., Altendorf A., Withall A., Sachdev P. Do people become more apathetic as they grow older? A longitudinal study in healthy individuals. Int. Psychogeriatr. 2010, 22:426-436.
5. Caeiro L., Ferro J.M., Costa J. Apathy secondary to stroke: a systematic review and meta-analysis. Cerebrovasc. Dis. Basel Switz. 2013, 35:23-39.
6. Clarke D.E., Ko J.Y., Lyketsos C., Rebok G.W., Eaton W.W. Apathy and cognitive and functional decline in community-dwelling older adults: results from the Baltimore ECA longitudinal study. Int. Psychogeriatr. IPA 2010, 22:819-829.
7. Foussias, G., Agid, O., Fervaha, G., Remington, G. Negative symptoms of schizophrenia: Clinical features, relevance to real world functioning and specificity versus other CNS disorders. Eur. Neuropsychopharmacol, [Epub ahead of print]. doi:10.1016/j.euroneuro.2013.10.017.
8. Friman P.C., Poling A. Making life easier with effort: basic findings and applied research on response effort. J. Appl. Behav. Anal. 1995, 28:583-590.
9. Gold J.M., Strauss G.P., Waltz J.A., Robinson B.M., Brown J.K., Frank M.J. Negative symptoms of schizophrenia are associated with abnormal effort-cost computations. Biol. Psychiat. 2013, 74:130-136.
10. Hartmann M.N., Hager O.M., Tobler P.N., Kaiser S. Parabolic discounting of monetary rewards by physical effort. Behav. Process. 2013, 100:192-196.
11. Kable J.W., Glimcher P.W. The neural correlates of subjective value during intertemporal choice. Nat. Neurosci. 2007, 10:1625-1633.
12. Kivetz R. The effects of effort and intrinsic motivation on risky choice. Mark. Sci. 2003, 22:477-502.
13. Kool W., McGuire J.T., Rosen Z.B., Botvinick M.M. Decision making and the avoidance of cognitive demand. J. Exp. Psychol. Gen. 2010, 139:665-682.
14. Kurniawan I.T., Seymour B., Talmi D., Yoshida W., Chater N., Dolan R.J. Choosing to make an effort: the role of striatum in signaling physical effort of a chosen action. J. Neurophysiol. 2010, 104:313-321.
15. Kurniawan I.T., Guitart-Masip M., Dolan R.J.( Dopamine and effort-based decision making. Front. Neurosci. 2011, 5.
16. Levy R., Dubois B. Apathy and the functional anatomy of the prefrontal cortex-basal ganglia circuits. Cereb. Cortex N. Y. N 2006, 1991(16):916-928.
17. Lovibond P.F., Lovibond S.H. The structure of negative emotional states: comparison of the depression anxiety stress scales (DASS) with the Beck depression and anxiety inventories. Behav. Res. Ther. 1995, 33:335-343.
18. Marin R.S., Wilkosz P.A. Disorders of diminished motivation. J. Head Trauma Rehabil. 2005, 20:377-388.
19. Marin R.S., Biedrzycki R.C., Firinciogullari S. Reliability and validity of the apathy evaluation scale. Psychiat. Res. 1991, 38:143-162.
20. Pedersen K.F., Alves G., Aarsland D., Larsen J.P. Occurrence and risk factors for apathy in Parkinson disease: a 4-year prospective longitudinal study. J. Neurol. Neurosurg. Psychiat. 2009, 80:1279-1282.
21. Robert P.H., Mulin E., Malléa P., David R. Review: apathy diagnosis, assessment, and treatment in Alzheimer's disease. CNS Neurosci. Ther. 2010, 16:263-271.
22. Rochat L., der Linden M.V., Renaud O., Epiney J.-B., Michel P., Sztajzel R., Spierer L., Annoni J.-M. Poor reward sensitivity and apathy after stroke implication of basal ganglia. Neurology 2013, 81:1674-1680.
23. Schmidt L., d' Arc B.F., Lafargue G., Galanaud D., Czernecki V., Grabli D., Schüpbach M., Hartmann A., Lévy R., Dubois B., et al. Disconnecting force from money: effects of basal ganglia damage on incentive motivation. Brain 2008, 131:1303-1310.
24. Snaith R.P., Hamilton M., Morley S., Humayan A., Hargreaves D., Trigwell P. A scale for the assessment of hedonic tone the Snaith-Hamilton pleasure scale. Br. J. Psychiat. J. Ment. Sci. 1995, 167:99-103.
25. Sockeel P., Dujardin K., Devos D., Denève C., Destée A., Defebvre L. The Lille apathy rating scale (LARS), a new instrument for detecting and quantifying apathy: validation in Parkinson's disease. J. Neurol. Neurosurg. Psychiat. 2006, 77:579-584.
26. Starkstein S.E., Mayberg H.S., Preziosi T.J., Andrezejewski P., Leiguarda R., Robinson R.G. Reliability, validity, and clinical correlates of apathy in Parkinson's disease. J. Neuropsych. Clin. Neurosci. 1992, 4:134-139.
27. Stuss D.T., Van Reekum R., Murphy K. Differentiation of states and causes of apathy. Neuropsychol. Emotion 2000, 340-363.
28. Treadway M.T., Zald D.H. Reconsidering anhedonia in depression: lessons from translational neuroscience. Neurosci. Biobehav. Rev. 2011, 35:537-555.
29. Treadway M.T., Buckholtz J.W., Schwartzman A.N., Lambert W.E., Zald D.H. Worth the "EEfRT"? The effort expenditure for rewards task as an objective measure of motivation and anhedonia. PLoS ONE 2009, 4:e6598.
30. Treadway M.T., Bossaller N.A., Shelton R.C., Zald D.H. Effort-based decision-making in major depressive disorder: a translational model of motivational anhedonia. J. Abnorm. Psychol. 2012, 121:553-558.
31. Van Reekum R., Stuss D.T., Ostrander L. Apathy: Why Care?. J. Neuropsychiatry Clin. Neurosci. 2005, 17:7-19.
32. Vansteenkiste M., Lens W., De Witte S., De Witte H., Deci E.L. The "why" and "why not" of job search behaviour: their relation to searching, unemployment experience, and well-being. Eur. J. Soc. Psychol. 2004, 34:345-363.
33. Vansteenkiste V., Lens W., De Witte H., Feather N.T. Understanding unemployed people's job search behaviour, unemployment experience and well-being: a comparison of expectancy-value theory and self-determination theory. Br. J. Soc. Psychol. 2005, 44:269-287.
34. Walton M.E., Kennerley S.W., Bannerman D.M., Phillips P.E.M., Rushworth M.F.S. Weighing up the benefits of work: behavioral and neural analyses of effort-related decision making. Neural Netw. Off. J. Int. Neural Netw. Soc. 2006, 19:1302-1314.