Targeting of AIDS related encephalopathy using phenylalanine anchored lipidic nanocarrier

Colloids and Surfaces B: Biointerfaces

Volumn 131, Issue , 2015, Pages 155-161

  Vyas, Anil ^a   Jain, Ankit ^a   Hurkat, Pooja ^a   Jain, Ashish ^a   Jain, Sanjay K ^a  

^a DR H S GOUR UNIVERSITY   (India)

Author keywords

BBB; Efavirenz; HIV; HIV associated dementia; Phenylalanine; SLN

Indexed keywords

AMINO ACIDS; BIOCHEMISTRY; BIOCOMPATIBILITY; CHEMICAL ANALYSIS; DRUG PRODUCTS; NEURODEGENERATIVE DISEASES; NUTRIENTS; SPECTROSCOPIC ANALYSIS;

BBB; EFAVIRENZ; HIV; HIV ASSOCIATED DEMENTIA; PHENYLALANINE; SLN;

DISEASES;

EFAVIRENZ; PHENYLALANINE; SOLID LIPID NANOPARTICLE; BENZOXAZINE DERIVATIVE; DRUG CARRIER; LIPID; NANOPARTICLE; RNA DIRECTED DNA POLYMERASE INHIBITOR;

ACTIVE TRANSPORT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG RELEASE; FEMALE; HIV ASSOCIATED DEMENTIA; IN VITRO STUDY; IN VIVO STUDY; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; RAT; TIME TO MAXIMUM PLASMA CONCENTRATION; VIRUS LOAD; ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANIMAL; BRAIN DISEASES; CELL CULTURE; CHEMISTRY; COMPLICATION; FLUORESCENCE MICROSCOPY; HUMAN; METABOLISM; SCANNING ELECTRON MICROSCOPY; TISSUE DISTRIBUTION; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE; WISTAR RAT;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ANIMALS; BENZOXAZINES; BLOOD-BRAIN BARRIER; BRAIN DISEASES; CELLS, CULTURED; DRUG CARRIERS; FEMALE; HUMANS; LIPIDS; MALE; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; MICROSCOPY, FLUORESCENCE; NANOPARTICLES; PHENYLALANINE; RATS, WISTAR; REVERSE TRANSCRIPTASE INHIBITORS; TISSUE DISTRIBUTION;

EID: 84929323579     PISSN: 09277765     EISSN: 18734367     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2015.04.049     Document Type: Article

References (31)

1. McArthur J.C., Steiner J., Sacktor N., Nath A. Human immunodeficiency virus-associated neurocognitive disorders: mind the gap. Ann. Neurol. 2010, 67:699-714.
2. Chun T.-W., Fauci A.S. Latent reservoirs of HIV: obstacles to the eradication of virus. Proc. Natl. Acad. Sci. U. S. A. 1999, 96:10958-10961.
3. Kaul M., Zheng J., Okamoto S., Gendelman H., Lipton S. HIV-1 infection and AIDS: consequences for the central nervous system. Cell Death Differ. 2005, 12:878-892.
4. das Neves J., Amiji M.M., Bahia M.F., Sarmento B. Nanotechnology-based systems for the treatment and prevention of HIV/AIDS. Adv. Drug Deliv. Rev. 2010, 62:458-477.
5. Donnerer J., Kronawetter M., Kapper A., Haas I., Kessler H. Therapeutic drug monitoring of the HIV/AIDS drugs abacavir, zidovudine, efavirenz, nevirapine, indinavir, lopinavir, and nelfinavir. Pharmacology 2003, 69:197-204.
6. Wong H.L., Chattopadhyay N., Wu X.Y., Bendayan R. Nanotechnology applications for improved delivery of antiretroviral drugs to the brain. Adv. Drug Deliv. Rev. 2010, 62:503-517.
7. Rao K.S., Ghorpade A., Labhasetwar V. Targeting Anti-HIV Drugs to the CNS 2009.
8. Varatharajan L., Thomas S.A. The transport of anti-HIV drugs across blood-CNS interfaces: summary of current knowledge and recommendations for further research. Antivir. Res. 2009, 82:A99-A109.
9. Liner K.J.II, Ro M.J., Robertson K.R. HIV, antiretroviral therapies, and the brain. Curr. HIV/AIDS Rep. 2010, 7:85-91.
10. Best B.M., Goicoechea M. Efavirenz-Still First-line King? 2008.
11. Dirson G., Fernandez C., Hindlet P., Roux F., German-Fattal M., Gimenez F., Farinotti R. Efavirenz does not interact with the ABCB1 transporter at the blood-brain barrier. Pharm. Res. 2006, 23:1525-1532.
12. Kaur I.P., Bhandari R., Bhandari S., Kakkar V. Potential of solid lipid nanoparticles in brain targeting. J. Control. Release 2008, 127:97-109.
13. Chattopadhyay N., Zastre J., Wong H.-L., Wu X.Y., Bendayan R. Solid lipid nanoparticles enhance the delivery of the HIV protease inhibitor, atazanavir, by a human brain endothelial cell line. Pharm. Res. 2008, 25:2262-2271.
14. Löscher W., Potschka H. Blood-brain barrier active efflux transporters: ATP-binding cassette gene family. NeuroRx 2005, 2:86-98.
15. Brasnjevic I., Steinbusch H.W., Schmitz C., Martinez-Martinez P. Delivery of peptide and protein drugs over the blood-brain barrier. Prog. Neurobiol. 2009, 87:212-251.
16. Tsuji A. Small molecular drug transfer across the blood-brain barrier via carrier-mediated transport systems. NeuroRx 2005, 2:54-62.
17. Lockman P.R., Oyewumi M.O., Koziara J.M., Roder K.E., Mumper R.J., Allen D.D. Brain uptake of thiamine-coated nanoparticles. J. Control. Release 2003, 93:271-282.
18. Hu F., Yuan H., Zhang H., Fang M. Preparation of solid lipid nanoparticles with clobetasol propionate by a novel solvent diffusion method in aqueous system and physicochemical characterization. Int. J. Pharm. 2002, 239:121-128.
19. Gupta Y., Jain A., Jain P., Jain S.K. Design and development of folate appended liposomes for enhanced delivery of 5-FU to tumor cells. J. Drug Target. 2007, 15:231-240.
20. Mehnert W., Mäder K. Solid lipid nanoparticles: production, characterization and applications. Adv. Drug Deliv. Rev. 2001, 47:165-196.
21. Fry D.W., White J.C., Goldman I.D. Rapid separation of low molecular weight solutes from liposomes without dilution. Anal. Biochem. 1978, 90:809-815.
22. Ramachandran G., Kumar A., Swaminathan S., Venkatesan P., Kumaraswami V., Greenblatt D.J. Simple and rapid liquid chromatography method for determination of efavirenz in plasma. J. Chromatogr. B 2006, 835:131-135.
23. Gupta Y., Soni V., Chourasia M., Jain A., Khare P., Jain S. Targeted drug delivery to the brain via transferrin coupled liposomes. Drug Deliv. Technol. 2005, 5:66-71.
24. Gumbleton M., Stephens D.J. Coming out of the dark: the evolving role of fluorescence imaging in drug delivery research. Adv. Drug Deliv. Rev. 2005, 57:5-15.
25. Bishnoi M., Jain A., Hurkat P., Jain S.K. Aceclofenac-loaded chondroitin sulfate conjugated SLNs for effective management of osteoarthritis. J. Drug Target. 2014, 1-8.
26. Kharya P., Jain A., Gulbake A., Shilpi S., Jain A., Hurkat P., Majumdar S., Jain S.K. Phenylalanine-coupled solid lipid nanoparticles for brain tumor targeting. J. Nanopart. Res. 2013, 15:1-12.
27. Schubert M., Müller-Goymann C. Solvent injection as a new approach for manufacturing lipid nanoparticles-evaluation of the method and process parameters. Eur. J. Pharm. Biopharm. 2003, 55:125-131.
28. Parhi R., Suresh P. Preparation and characterization of solid lipid nanoparticles-a review. Curr. Drug Discov. Technol. 2012, 9:2-16.
29. Rai A., Jain A., Jain A., Jain A., Pandey V., Chashoo G., Soni V., Sharma P.R. Targeted SLNs for management of HIV-1 associated dementia. Drug Dev. Ind. Pharm. 2014, 1-7.
30. Jain A., Gulbake A., Jain A., Shilpi S., Hurkat P., Jain S.K. Dual drug delivery using smart liposomes for triggered release of anticancer agents. J. Nanopart. Res. 2013, 15:1-12.
31. Jain A., Jain S.K. Brain targeting using surface functionalized nanocarriers in human solid tumors. Drug Nanocarriers 2014, 203-255. Series Nanobiomedicine Studium Press, Houston LLC, USA. B. Singh, N.K. Jain, O.P. Katare (Eds.).