Insulin resistance-associated interhemispheric functional connectivity alterations in T2DM: A resting-state fMRI study

BioMed Research International

Volumn 2015, Issue , 2015, Pages

  Xia, Wenqing ^a,b   Wang, Shaohua ^c   Spaeth, Andrea M ^b   Rao, Hengyi ^b   Wang, Pin ^a   Yang, Yue ^a   Huang, Rong ^a   Cai, Rongrong ^a   Sun, Haixia ^a  

^a MEDICAL SCHOOL OF SOUTHEAST UNIVERSITY   (China)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c SOUTHEAST UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN A1C;

ADULT; AGED; ARTICLE; BRAIN FUNCTION; BRAIN REGION; CLINICAL ARTICLE; CLINICAL ASSESSMENT; CLINICAL STUDY; COGNITIVE DEFECT; CONTROLLED STUDY; DEFAULT MODE NETWORK; DISEASE ASSOCIATION; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GLUCOSE HOMEOSTASIS; HUMAN; IMAGE PROCESSING; INSULIN RESISTANCE; INTERHEMISPHERIC FUNCTIONAL CONNECTIVITY; MALE; MIDDLE TEMPORAL GYRUS; NEUROPATHOLOGY; NEUROPSYCHOLOGICAL TEST; NON INSULIN DEPENDENT DIABETES MELLITUS; NUCLEAR MAGNETIC RESONANCE SCANNER; PSYCHOLOGIC TEST; RESTING STATE FUNCTIONAL CONNECTIVITY; RESTING STATE NETWORK; SUPERIOR FRONTAL GYRUS; VOXEL MIRRORED HOMOTOPIC CONNECTIVITY; BRAIN MAPPING; COGNITION DISORDERS; COMPLICATION; DIAGNOSTIC IMAGING; FRONTAL LOBE; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PHYSIOLOGY; RADIOGRAPHY; TEMPORAL LOBE;

ADULT; AGED; BRAIN MAPPING; COGNITION DISORDERS; DIABETES MELLITUS, TYPE 2; FEMALE; FRONTAL LOBE; HUMANS; INSULIN RESISTANCE; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; RADIOGRAPHY; TEMPORAL LOBE;

EID: 84929300724     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2015/719076     Document Type: Article

References (41)

1. J. A. Luchsinger, C. Reitz, B. Patel, M.-X. Tang, J. J. Manly, and R.Mayeux, "Relation of diabetes to mild cognitive impairment, " Archives of Neurology, vol. 64, no. 4, pp. 570-575, 2007.
2. Z. Arvanitakis, R. S.Wilson, J. L. Bienias, D. A. Evans, and D. A. Bennett, "Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function, " Archives of Neurology, vol. 61, no. 5, pp. 661-666, 2004.
3. W. Xia, S. Wang, Z. Sun et al., "Altered baseline brain activity in type 2 diabetes: a resting-state fMRI study, " Psychoneuroendocrinology, vol. 38, no. 11, pp. 2493-2501, 2013.
4. H. Zhou, W. Lu, Y. Shi et al., "Impairments in cognition and resting-state connectivity of the hippocampus in elderly subjects with type 2 diabetes, " Neuroscience Letters, vol. 473, no. 1, pp. 5-10, 2010.
5. E. S. C. Korf, L.R.White, P.H. Scheltens, andL. J. Launer, "Brain aging in very old men with type 2 diabetes: the Honolulu-Asia Aging Study, " Diabetes Care, vol. 29, no. 10, pp. 2268-2274, 2006.
6. Z.-Y. Chen, J.-F. Li, J. Sun, and L. Ma, "Changes in subcortical whitematter and corpus callosum volumes in patientswith type II diabetes mellitus, " Acta AcademiaeMedicinae Sinicae, vol. 35, no. 5, pp. 503-514, 2013.
7. J. Zhang, Y. Wang, J. Wang, X. Zhou, N. Shu, and Z. Zhang, "White matter integrity disruptions associated with cognitive impairments in type 2 diabetes patients, " Diabetes, vol. 63, no. 11, pp. 3596-3605, 2014.
8. S. J. Dimond, "Performance by split-brain humans on lateralized vigilance tasks, " Cortex, vol. 15, no. 1, pp. 43-50, 1979.
9. J. J. Sidtis, B. T. Volpe, J. D.Holtzman, D. H. Wilson, and M. S. Gazzaniga, "Cognitive interaction after staged callosal section: evidence for transfer of semantic activation, " Science, vol. 212, no. 4492, pp. 344-346, 1981.
10. J. Liederman, "The dynamics of interhemispheric collaboration and hemispheric control, " Brain and Cognition, vol. 36, no. 2, pp. 193-208, 1998.
11. Y. Lakmache, M. Lassonde, S. Gauthier, J.-Y. Frigon, and F. Lepore, "Interhemispheric disconnection syndrome in Alzheimer's disease, " Proceedings of the National Academy of Sciences of the United States of America, vol. 95, no. 15, pp. 9042-9046, 1998.
12. J. S. Anderson, T. J. Druzgal, A. Froehlich et al., "Decreased interhemispheric functional connectivity in autism, " Cerebral Cortex, vol. 21, no. 5, pp. 1134-1146, 2011.
13. W.-Q. Zhao and M. Townsend, "Insulin resistance and amyloidogenesis as common molecular foundation for type 2 diabetes and Alzheimer's disease, " Biochimica et Biophysica Acta: Molecular Basis of Disease, vol. 1792, no. 5, pp. 482-496, 2009.
14. T. Matsuzaki, K. Sasaki, Y. Tanizaki et al., "Insulin resistance is associated with the pathology of Alzheimer disease: the Hisayama study, " Neurology, vol. 75, no. 9, pp. 764-770, 2010.
15. G.Musen, A.M. Jacobson, N. R. Bolo et al., "Resting-state brain functional connectivity is altered in type 2 diabetes, " Diabetes, vol. 61, no. 9, pp. 2375-2379, 2012.
16. X.-N. Zuo, C. Kelly, A. DiMartino et al., "Growing together and growing apart: regional and sex differences in the lifespan developmental trajectories of functional homotopy, " The Journal of Neuroscience, vol. 30, no. 45, pp. 15034-15043, 2010.
17. C. Kelly, X.-N. Zuo, K. Gotimer et al., "Reduced interhemispheric resting state functional connectivity in cocaine addiction, " Biological Psychiatry, vol. 69, no. 7, pp. 684-692, 2011.
18. M. J. Hoptman, X.-N. Zuo, D. D'Angelo et al., "Decreased interhemispheric coordination in schizophrenia: a resting state fMRI study, " Schizophrenia Research, vol. 141, no. 1, pp. 1-7, 2012.
19. W. Guo, F. Liu, Z. Xue et al., "Decreased interhemispheric coordination in treatment-resistant depression: a resting-state FMRI study, " PLoS ONE, vol. 8, no. 8, Article ID e71368, 2013.
20. K. G. M. M. Alberti and P. Z. Zimmet, "Definition, diagnosis and classification of diabetesmellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus. Provisional report of aWHO consultation, " DiabeticMedicine, vol. 15, no. 7, pp. 539-553, 1998.
21. C.-G. Yan and Y.-F. Feng, "DPARSF: a MATLAB toolbox for 'pipeline' data analysis of resting-state fMRI, " Frontiers in System Neuroscience, vol. 4, article 13, 2010.
22. J. Ashburner and K. J. Friston, "Unified segmentation, " NeuroImage, vol. 26, no. 3, pp. 839-851, 2005.
23. C.Delmaire, E.M. Dumas, M. A. Sharmanet al., "The structural correlates of functional deficits in early huntington's disease, " Human Brain Mapping, vol. 34, no. 9, pp. 2141-2153, 2013.
24. L. Bäckman, T.-B. Robins-Wahlin, A. Lundin, N. Ginovart, and L. Farde, "Cognitive deficits in Huntington's disease are predicted by dopaminergic PET markers and brain volumes, " Brain, vol. 120, no. 12, pp. 2207-2217, 1997.
25. Y. Zhang, X. Zhang, J. Zhang et al., "Gray matter volume abnormalities in type 2 diabetes mellitus with and without mild cognitive impairment, " Neuroscience Letters, vol. 562, pp. 1-6, 2014.
26. K. Kamiyama, A.Wada, M. Sugihara et al., "Potential hippocampal region atrophy in diabetes mellitus type 2: a voxel-based morphometry VSRAD study, " Japanese Journal of Radiology, vol. 28, no. 4, pp. 266-272, 2010.
27. C. M. Falvey, C. Rosano, E. M. Simonsick et al., "Macro-and microstructural magnetic resonance imaging indices associated with diabetes among community-dwelling older adults, " Diabetes Care, vol. 36, no. 3, pp. 677-682, 2013.
28. W. S. Hoogenboom, T. J. Marder, V. L. Flores et al., "Cerebral white matter integrity and resting-state functional connectivity in middle-aged patients with type 2 diabetes, " Diabetes, vol. 63, no. 2, pp. 728-738, 2014.
29. S. Kullmann, M. Heni, R. Veit et al., "The obese brain: association of bodymass index and insulin sensitivity with resting state network functional connectivity, " Human Brain Mapping, vol. 33, no. 5, pp. 1052-1061, 2012.
30. C. E.Greenwood andG.Winocur, "High-fat diets, insulin resistance and declining cognitive function, " Neurobiology of Aging, vol. 26, pp. S42-S45, 2005.
31. L. D. Baker, D. J. Cross, S. Minoshima, D. Belongia, G. Stennis Watson, and S. Craft, "Insulin resistance and alzheimer-like reductions in regional cerebral glucose metabolism for cognitively normal adults with prediabetes or early type 2 diabetes, " Archives of Neurology, vol. 68, no. 1, pp. 51-57, 2011.
32. M. Rotte, C. Baerecke, G. Pottag et al., "Insulin affects the neuronal response in the medial temporal lobe in humans, " Neuroendocrinology, vol. 81, no. 1, pp. 49-55, 2005.
33. H. Kenna, F. Hoeft, R. Kelley et al., "Fasting plasma insulin and the default mode network in women at risk for Alzheimer's disease, " Neurobiology of Aging, vol. 34, no. 3, pp. 641-649, 2013.
34. A. Convit, "Links between cognitive impairment in insulin resistance: an explanatory model, " Neurobiology of Aging, vol. 26, pp. S31-S35, 2005.
35. J. Qiu, H. Li, J. Jou et al., "Neural correlates of the 'Aha' experiences: evidence froman fMRI study of insight problem solving, " Cortex, vol. 46, no. 3, pp. 397-403, 2010.
36. H. Braak and E. Braak, "Neuropathological stageing of Alzheimer-related changes, " Acta Neuropathologica, vol. 82, no. 4, pp. 239-259, 1991.
37. W. de Haan, K.Mott, E. C.W. van Straaten, P. Scheltens, and C. J. Stam, "Activity dependent degeneration explains hub vulnerability in Alzheimer's disease, " PLoS Computational Biology, vol. 8, no. 8, Article ID e1002582, 2012.
38. W. W. Seeley, "Divergent network connectivity changes in healthy APOE ε4 carriers: disinhibition or compensation?" Archives of Neurology, vol. 68, no. 9, pp. 1107-1108, 2011.
39. E. M. Moore, A. G. Mander, D. Ames et al., "Increased risk of cognitive impairment in patients with diabetes is associated with metformin, " Diabetes Care, vol. 36, no. 10, pp. 2981-2987, 2013.
40. C.-C. Hsu, M. L. Wahlqvist, M.-S. Lee, and H.-N. Tsai, "Incidence of dementia is increased in type 2 diabetes and reduced by the use of sulfonylureas and metformin, " Journal of Alzheimer's Disease, vol. 24, no. 3, pp. 485-493, 2011.
41. A. M. Abbatecola, F. Lattanzio, A. M. Molinari et al., "Rosiglitazone and cognitive stability in older individuals with type 2 diabetes andmild cognitive impairment, " Diabetes Care, vol. 33, no. 8, pp. 1706-1711, 2010.