Can age at sexual maturity act as a predictive biomarker for prodromal negative symptoms?

Schizophrenia Research

Volumn 164, Issue 1-3, 2015, Pages 35-39

  Ramanathan, Seethalakshmi ^a,b   Miewald, Jean ^c   Montrose, Debra ^c   Keshavan, Matcheri S ^c,d,e  

^a Hutchings Psychiatric Center   (United States)

^b SUNY UPSTATE MEDICAL UNIVERSITY   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

^d BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Biomarker; Negative symptoms; Psychosis; Puberty; Tanner stage

Indexed keywords

BIOLOGICAL MARKER;

ADOLESCENT; ADULT; AGE; ARTICLE; CHILD; CONTROLLED STUDY; DISEASE ASSESSMENT; DISEASE SEVERITY; FEMALE; HUMAN; INTERVIEW; MAJOR CLINICAL STUDY; MALE; MENTAL DISEASE; NEGATIVE SYNDROME; PREDICTION; PRIORITY JOURNAL; PRODROMAL SYMPTOM; PUBERTY; REGRESSION ANALYSIS; SCALE OF PRODROMAL SYMPTOMS; SCHIZOPHRENIA; SEXUAL MATURITY; TANNER MATURATIONAL SCALE; AGING; METABOLISM; PSYCHOLOGICAL RATING SCALE; RISK FACTOR;

ADOLESCENT; AGING; BIOMARKERS; CHILD; FEMALE; HUMANS; MALE; PRODROMAL SYMPTOMS; PSYCHIATRIC STATUS RATING SCALES; REGRESSION ANALYSIS; RISK FACTORS; SCHIZOPHRENIA;

EID: 84929281008     PISSN: 09209964     EISSN: 15732509     Source Type: Journal    
DOI: 10.1016/j.schres.2015.02.019     Document Type: Article

References (48)

1. Ahima R.S., Dushay J., Flier S.N., Prabakaran D., Flier J.S. Leptin accelerates the onset of puberty in normal female mice. J. Clin. Invest. 1997, 99(3):391-395.
2. Aubele T., Kritzer M.F. Androgen influence on prefrontal dopamine systems in adult male rats: localization of cognate intracellular receptors in medial prefrontal projections to the ventral tegmental area and effects of gonadectomy and hormone replacement on glutamate-stimulated extracellular dopamine level. Cereb. Cortex 2012, 22(8):1799-1812.
3. Bergemann N., Parzer P., Nagl I., Salbach B., Runnebaum B., Mundt C., Resch F. Acute psychiatric admission and menstrual cycle phase in women with schizophrenia. Arch. Womens Ment. Health 2002, 5(3):119-126.
4. Bialek M., Zaremba P., Borowicz K.K., Czuczwar S.J. Neuroprotective role of testosterone in the nervous system. Pol. J. Pharmacol. 2004, 56:509-518.
5. Blanton R.E., Levitt J.G., Peterson J.R., Fadale D., Sporty M.L., Lee M., McCracken J.T. Gender differences in the left inferior frontal gyrus in normal children. Neuroimage 2004, 22(2):626-636.
6. Campion D., Thibaut F., Denise P., Courtin P., Pottier M., Levillain D. SPEM impairment in drug-naive schizophrenic patients: evidence for a trait marker. Biol. Psychiatry 1992, 32(10):891-902.
7. Ceskova E., Prikryl R., Kasparek T. Testosterone in first-episode schizophrenia. Neuro Endocrinol. Lett. 2007, 28(6):811-814.
8. Chan R.C., Xu T., Heinrichs R.W., Yu Y., Wang Y. Neurological soft signs in schizophrenia: a meta-analysis. Schizophr. Bull. 2010, 36(6):1089-1104.
9. Cohen R.Z., Seeman M.V., Gotowiec A., Kopala L. Earlier puberty as a predictor of later onset of schizophrenia in women. Am. J. Psychiatr. 1999, 156(7):1059-1065.
10. Desmond N.L., Levy W.B. Ovarian steroidal control of connectivity in the female hippocampus: an overview of recent experimental findings and speculations on its functional consequences. Hippocampus 1997, 7(2):239-245.
11. Faraone S.V., Chen W.J., Goldstein J.M., Tsuang M.T. Gender differences in age at onset of schizophrenia. Br. J. Psychiatry 1994, 164(5):625-629.
12. First M., Spitzer R., Gibbon M., Williams J. Structured clinical interview for DSM-IV-TR axis I disorders, research version, non-patient edition (SCID-I/NP) 2002, New York State Psychiatric Institute, New York, (Biometrics Research).
13. Grumbach M.M. The neuroendocrinology of human puberty revisited. Horm. Res. 2002, 57(Suppl. 2):2-14.
14. Gruzelier J.H., Kaiser J. Syndromes of schizotypy and timing of puberty. Schizophr. Res. 1996, 21(3):183-194.
15. Gur R.E., Petty R.G., Turetsky B.I., Gur R.C. Schizophrenia throughout life: sex differences in severity and profile of symptoms. Schizophr. Res. 1996, 21(1):1-12.
16. Heinrichs D.W., Buchanan R.W. Significance and meaning of neurological signs in schizophrenia. Am. J. Psychiatry 1988, 145(1):11-18.
17. Huber T.J., Tettenborn C., Leifke E., Emrich H.M. Sex hormones in psychotic men. Psychoneuroendocrinology 2005, 30(1):111-114.
18. Jablensky A., Sartorius N., Ernberg G., Anker M., Korten A., Cooper J., Bertelsen A. Schizophrenia: manifestations, incidence and course in different cultures A World Health Organization ten-country study. Psychol. Med. Monogr. Suppl. 1992, 20:1-97.
19. Jordan C.L., Watamura S., Arnold A.P. Androgenic, not estrogenic, steroids alter neuromuscular synapse elimination in the rat levator ani. Dev. Brain Res. 1995, 84(2):225-232.
20. Kendell R.E., Chalmers J.C., Platz C. Epidemiology of puerperal psychoses. Br. J. Psychiatry 1987, 150:662-673.
21. Keshavan M.S., Hogarty G.E. Brain maturational processes and delayed onset in schizophrenia. Dev. Psychopathol. 1999, 11(03):525-543.
22. Keshavan M.S., Diwadkar V.A., Montrose D.M., Stanley J.A., Pettegrew J.W. Premorbid characterization in schizophrenia: the Pittsburgh High Risk study. World Psychiatry : Official Journal of the World Psychiatric Association (WPA) 2004, 3(3):163-168.
23. Ladouceur C.D. Neural systems supporting cognitive-affective interactions in adolescence: the role of puberty and implications for affective disorders. Front. Integr. Neurosci. 2012, 6:65.
24. Lee K., Williams L.M. Eye movement dysfunction as a biological marker of risk for schizophrenia. Aust. N. Z. J. Psychiatry 2000, 34(s2):S91-S100.
25. Mahe V., Dumaine A. Oestrogen withdrawal associated psychoses. Acta Psychiatr. Scand. 2001, 104(5):323-331.
26. Markham J.A. Sex steroids and schizophrenia. Rev. Endocr. Metab. Disord. 2012, 13(3):187-207.
27. Marshall W.A., Tanner J.M. Variations in pattern of pubertal changes in girls. Arch. Dis. Child. 1969, 44(235):291-303.
28. Marshall W.A., Tanner J.M. Variations in the pattern of pubertal changes in boys. Arch. Dis. Child. 1970, 45(239):13-23.
29. Miller T.J., McGlashan T.H., Rosen J.L., Somjee L., Markovich P.J., Stein K., Woods S.W. Prospective diagnosis of the initial prodrome for schizophrenia based on the structured interview for prodromal syndromes: preliminary evidence of interrater reliability and predictive validity. Am. J. Psychiatr. 2002, 159(5):863-865.
30. Mueser K.T., Bellack A.S., Morrison R.L., Wade J.H. Gender, social competence, and symptomatology in schizophrenia: a longitudinal analysis. J. Abnorm. Psychol. 1990, 99(2):138.
31. Nagai T., Tada M., Kirihara K., Araki T., Jinde S., Kasai K. Mismatch negativity as a "translatable" brain marker toward early intervention for psychosis: a review. Front. Psychiatry 2013, 4:115.
32. Neufang S., Specht K., Hausmann M., Gunturkun O., Herpertz-Dahlmann B., Fink G.R., Konrad K. Sex differences and the impact of steroid hormones on the developing human brain. Cereb. Cortex 2009, 19(2):464-473.
33. Nuñez J.L., Lauschke D.M., Juraska J.M. Cell death in the development of the posterior cortex in male and female rats. J. Comp. Neurol. 2001, 436(1):32-41.
34. Palaniyappan L., Liddle P.F. Aberrant cortical gyrification in schizophrenia: a surface-based morphometry study. J. Psychiatry Neurosci. 2012, 37(6):399-406.
35. Paus T. Mapping brain maturation and cognitive development during adolescence. Trends Cogn. Sci. 2005, 9(2):60-68.
36. Peper J.S., Brouwer R.M., Schnack H.G., van Baal G.C., van Leeuwen M., van den Berg Stéphanie M., Hulshoff Pol H.E. Sex steroids and brain structure in pubertal boys and girls. Psychoneuroendocrinology 2009, 34(3):332-342.
37. Peper J., Hulshoff Pol H., Crone E., Van Honk J. Sex steroids and brain structure in pubertal boys and girls: a mini-review of neuroimaging studies. Neuroscience 2011, 191:28-37.
38. Perrin J.S., Herve P.Y., Leonard G., Perron M., Pike G.B., Pitiot A., Paus T. Growth of white matter in the adolescent brain: role of testosterone and androgen receptor. J. Neurosci. 2008, 28(38):9519-9524.
39. Raznahan A., Lee Y., Stidd R., Long R., Greenstein D., Clasen L., Giedd J.N. Longitudinally mapping the influence of sex and androgen signaling on the dynamics of human cortical maturation in adolescence. Proc. Natl. Acad. Sci. U. S. A. 2010, 107(39):16988-16993.
40. Saugstad L.F. Age at puberty and mental illness. towards a neurodevelopmental aetiology of kraepelin's endogenous psychoses. Br. J. Psychiatry 1989, 155:536-544.
41. Slora E.J., Bocian A.B., Herman-Giddens M.E., Harris D.L., Pedlow S.E., Dowshen S.A., Wasserman R.C. Assessing inter-rater reliability (IRR) of tanner staging and orchidometer use with boys: a study from PROS. J. Pediatr. Endocrinol. Metab. 2009, 22(4):291-300.
42. Smith R.C., Hussain M.I., Chowdhury S.A., Stearns A. Stability of neurological soft signs in chronically hospitalized schizophrenic patients. J. Neuropsychiatry Clin. Neurosci. 1999, 11(1):91-96.
43. StataCorp Stata Statistical Software: Release 13 2013, StataCorp LP, College Station, TX.
44. Van Rijn S., Aleman A., de Sonneville L., Sprong M., Ziermans T., Schothorst P., Swaab H. Neuroendocrine markers of high risk for psychosis: salivary testosterone in adolescent boys with prodromal symptoms. Psychol. Med. 2011, 41(09):1815-1822.
45. Veldhuis J.D. Neuroendocrine mechanisms mediating awakening of the human gonadotropic axis in puberty. Pediatr. Nephrol. 1996, 10(3):304-317.
46. Wechsler D. Wechsler Adult Intelligence Scale-Revised 1981, Psychological Corporation.
47. Wechsler D. Wechsler Abbreviated Scale of Intelligence 1999, The Psychological Corporation: Harcourt Brace & Company, New York, NY.
48. Zehr J.L., Todd B.J., Schulz K.M., McCarthy M.M., Sisk C.L. Dendritic pruning of the medial amygdala during pubertal development of the male syrian hamster. J. Neurobiol. 2006, 66(6):578-590.