Structural and functional analyses of human tryptophan 2,3-dioxygenase

Proteins: Structure, Function and Bioinformatics

Volumn 82, Issue 11, 2014, Pages 3210-3216

  Meng, Bing ^a,b   Wu, Dong ^c   Gu, Jianhua ^d   Ouyang, Songying ^a   Ding, Wei ^a   Liu, Zhi Jie ^a,e  

^a INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c SHANGHAITECH UNIVERSITY   (China)

^d TIANJIN FIRST CENTRAL HOSPITAL   (China)

^e KUNMING MEDICAL UNIVERSITY   (China)

Author keywords

Crystal structure; Dioxygenase; Enzymatic activity; L tryptophan metabolism; TDO

Indexed keywords

TRYPTOPHAN; TRYPTOPHAN 2,3 DIOXYGENASE; HEME;

ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DNA LIBRARY; DNA SEQUENCE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME KINETICS; ENZYME METABOLISM; ENZYME PURIFICATION; ENZYME STRUCTURE; GEL PERMEATION CHROMATOGRAPHY; HANGING DROP VAPOR DIFFUSION METHOD; HUMAN; ISOTHERMAL TITRATION CALORIMETRY; MUTAGENESIS; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE ALIGNMENT; SITE DIRECTED MUTAGENESIS; SURFACE AREA; ULTRAVIOLET SPECTROPHOTOMETRY; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME ACTIVE SITE; GENETICS; KINETICS; METABOLISM; MOLECULAR GENETICS; OXIDATION REDUCTION REACTION; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; HEME; HUMANS; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OXIDATION-REDUCTION; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID; TRYPTOPHAN; TRYPTOPHAN OXYGENASE;

EID: 84929266674     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.24653     Document Type: Article

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