Contamination of the southern Baltic Sea waters by the residues of selected pharmaceuticals: Method development and field studies

Marine Pollution Bulletin

Volumn 94, Issue 1-2, 2015, Pages 62-71

  Borecka, Marta ^a   Siedlewicz, Grzegorz ^b   Haliński, Łukasz P ^a   Sikora, Kinga ^a   Pazdro, Ksenia ^b   Stepnowski, Piotr ^a   Białk Bielińska, Anna ^a  

^a UNIVERSITY OF GDA SK   (Poland)

^b INSTITUTE OF OCEANOLOGY   (Poland)

Author keywords

Baltic Sea; LC MS MS; Marine waters contamination; Matrix effects; Pharmaceutical residues; Uncertainty estimation

Indexed keywords

SEAWATER; UNCERTAINTY ANALYSIS; WATER POLLUTION;

BALTIC SEA; LC-MS/MS; MARINE WATERS; MATRIX EFFECTS; PHARMACEUTICAL RESIDUES; UNCERTAINTY ESTIMATION;

MARINE POLLUTION;

ENROFLOXACIN; IBUPROFEN; KETOPROFEN; NAPROXEN; OXOLINIC ACID; SULFADIMETHOXINE; SULFAMERAZINE; SULFAMETHOXAZOLE; SULFAPYRIDINE; SULFATHIAZOLE; TRIMETHOPRIM; DRUG; SEA WATER; WATER POLLUTANT;

CONCENTRATION (COMPOSITION); DRUG; LIQUID CHROMATOGRAPHY; MARINE POLLUTION; MASS SPECTROMETRY; SEAWATER; UNCERTAINTY ANALYSIS;

ARTICLE; BALTIC SEA; CHEMOMETRIC ANALYSIS; CONCENTRATION (PARAMETERS); ELECTROSPRAY MASS SPECTROMETRY; EXTRACTION; LIQUID CHROMATOGRAPHY; SEA POLLUTION; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; VALIDATION PROCESS; WATER ANALYSIS; WATER SAMPLING; ANALYSIS; BALTIC STATES; CHEMISTRY; ENVIRONMENTAL MONITORING; PROCEDURES; WATER POLLUTANT;

ATLANTIC OCEAN; BALTIC SEA;

BALTIC STATES; ENVIRONMENTAL MONITORING; PHARMACEUTICAL PREPARATIONS; SEAWATER; WATER POLLUTANTS, CHEMICAL;

EID: 84929264454     PISSN: 0025326X     EISSN: 18793363     Source Type: Journal    
DOI: 10.1016/j.marpolbul.2015.03.008     Document Type: Article

References (58)

1. Ando T., Nagase H. A novel method using cyanobacteria for ecotoxicity test of veterinary antimicrobial agents. Environ. Toxicol. Chem. 2007, 26:601-606.
2. Baran W., Sochacka J., Wardas W. Toxicity and biodegradability of sulfonamides and products of their photocatalytic degradation in aqueous solutions. Chemosphere 2006, 65:1295-1299.
3. Beck I.C., Bruhn R., Gandrass J., Ruck W. Liquid chromatography-tandem mass spectrometry analysis of estrogenic compounds in coastal surface water of the Baltic Sea. J. Chromatogr. A 2005, 1090:98-106.
4. Beck, I.C., Bruhn, R., Gandrass, J., Ruck, W., 2009. Estrogenic and Pharmaceutical Compounds - Investigations in the German Baltic Sea. Publications of GKSS Research Centre. http://www.coast.gkss.de/internet/Poster-Iris-2.pdf.
5. Bendz D., Paxéus N.A., Ginn T.R., Loge F.J. Occurrence and fate of pharmaceutically active compounds in the environment, a case study: Höje River in Sweden. J. Hazard. Mater. 2005, 122:195-204.
6. Benotti M.J., Brownawell B.J. Microbial degradation of pharmaceuticals in estuarine and coastal seawater. Environ. Pollut. 2009, 157:994-1002.
7. Boleda M.R., Galceran M.T., Ventura F. Validation and uncertainty estimation of a multiresidue method for pharmaceuticals in surface and treated waters by liquid chromatography-tandem mass spectrometry. J. Chromatogr. A 2013, 1286:146-158.
8. Borecka M., Białk-Bielińska A., Siedlewicz G., Kornowska K., Kumirska J., Stepnowski P., Pazdro K. A new approach for the estimation of expanded uncertainty of results of an analytical method developed for determining antibiotics in seawater using solid-phase extraction disks and liquid chromatography coupled with tandem mass spectrometry technique. J. Chromatogr. A 2013, 1304:138-146.
9. Boxall A.B.A., Kolpin D., Halling-Sørensen B., Tolls J. Are veterinary medicines causing environmental risks?. Environ. Sci. Technol. 2003, 37:286A-294A.
10. Brun G.L., Bernier M., Losier R., Doe K., Jackman P., Lee H. Pharmaceutically active compounds in Atlantic Canadian sewage treatment plant effluents and receiving waters, and potential for environmental effects as measured by acute and chronic aquatic toxicity. Environ. Toxicol. Chem. 2006, 25:2163-2176.
11. Caban M., Migowska N., Stepnowski P., Kwiatkowski M., Kumirska J. Matrix effects and recovery calculations in analyses of pharmaceuticals based on the determination of β-blockers and β-agonists in environmental samples. J. Chromatogr. A 2012, 1258:117-127.
12. Claessens M., Vanhaecke L., Wille K., Janssen C.R. Emerging contaminants in Belgian marine waters: single toxicant and mixture risks of pharmaceuticals. Mar. Pollut. Bull. 2013, 71:41-50.
13. Cleuvers M. Mixture toxicity of the anti-inflammatory drugs diclofenac, ibuprofen, naproxen, and acetylsalicylic acid. Ecotoxicol. Environ. Saf. 2004, 59:309-315.
14. Commission Decision 2002/657/EC of 12 August 2002 Implementing Council Directive 96/23/EC Establishes Criteria and Procedures for the Validation of Analytical Methods to Ensure the Quality and Comparability of Analytical Results Generated by Official Laboratories.
15. Council Directive 96/23/EC of 29 April 1996 on Measures to Monitor Certain Substances and Residues thereof in live Animals and Animal Products and Repealing Directives 85/358/EEC and 86/469/EEC and Decision 89/187/EEC and 91/664/EEC.
16. Eguchi K., Nagase H., Ozawa M., Endoh Y.S., Goto K., Hirata K., Miyamoto K., Yoshimura H. Evaluation of antimicrobial agents for veterinary use in the ecotoxicity test using microalgae. Chemosphere 2004, 57:1733-1738.
17. Fent K. Effects of pharmaceuticals on aquatic organisms. Pharmaceuticals in the Environment - Sources, Fate, Effects and Risks 2008, 174-203. Springer-Verlag. K. Kümmerer (Ed.).
18. Fent K., Weston A.A., Caminada D. Ecotoxicology of human pharmaceuticals. Aquat. Toxicol. 2006, 76:122-159.
19. Ferrari B., Paxéus N., Lo Giudice R., Pollio A., Garric J. Ecotoxicological impact of pharmaceuticals found in treated wastewaters: study of carbamazepine, clofibric acid, and diclofenac. Ecotoxicol. Environ. Saf. 2003, 55:359-370.
20. Ferrari B., Mons R., Vollat B., Fraysse B., Paxeaus N., Lo Giudice R., Pollio A., Garric J. Environmental risk assessment of six human pharmaceuticals: are the current environmental risk assessment procedures sufficient for the protection of the aquatic environment?. Environ. Toxicol. Chem. 2004, 23:1344-1354.
21. Guide to the Expression of Uncertainty in Measurement (GUM), 1993. Geneva: International Organisation for Standardisation.
22. Haller M.Y., Müller S.R., McArdell C.S., Alder A.C., Suter M.J.F. Quantification of veterinary antibiotics (sulfonamides and trimethoprim) in animal manure by liquid chromatography-mass spectrometry. J. Chromatogr. A 2002, 952:111-120.
23. Halling-Sørensen B., HoltenLützhøft H.C., Andersen H.R., Ingerslev F. Environmental risk assessment of antibiotics: comparison of mecillinam, trimethoprim and ciprofloxacin. J. Antimicrob. Chemother. 2000, 46:53-58.
24. Harada A., Komori K., Nakada N., Kitamura K., Suzuki Y. Biological effects of PPCPs on aquatic lives and evaluation of river waters affected by different wastewater treatment levels. Water Sci. Technol. 2008, 58:1541-1546.
25. Hebig K.H., Nödler K., Licha T., Scheytt T.J. Impact of materials used in lab and field experiments on the recovery of organic micropollutants. Sci. Total Environ. 2014, 473-474:125-131.
26. HELCOM, 2010. Hazardous substances in the Baltic Sea - An integrated thematic assessment of hazardous substances in the Baltic Sea. Balt. Sea Environ. Proc. No. 120B.
27. Hoeger B., Köllner B., Dietrich D.R., Hitzfeld B. Water-borne diclofenac affects kidney and gill integrity and selected immune parameters in brown trout (Salmo trutta f. fario). Aquat. Toxicol. 2005, 75:53-64.
28. HoltenLützhøft H.C., Halling-Sørensen B., Jorgensen S.E. Algal toxicity of antibacterial agents applied in Danish fish farming. Arch. Environ. Contam. Toxicol. 1999, 36:1-6.
29. Isidori M., Lavorgna M., Nardelli A., Pascarella L., Parrella A. Toxic and genotoxic evaluation of six antibiotics on non-target organisms. Sci. Total Environ. 2005, 346:87-98.
30. IUCLID dataset, 2000. Ibuprofen. European Commission - European Chemicals Bureau, pp. 1-44.
31. Kasprzyk-Hordern B., Dinsdale R.M., Guwy A.J. The removal of pharmaceuticals, personal care products, endocrine disruptors and illicit drugs during wastewater treatment and its impact on the quality of receiving waters. Water Res. 2009, 43:363-380.
32. Konieczka P., Namieśnik J. Estimating uncertainty in analytical procedures based on chromatographic techniques. J. Chromatogr. A 2010, 1217:882-891.
33. Kot-Wasik A., Debska J., Wasik A., Namieśnik J. Determination of non-steroidal anti-inflammatory drugs in natural waters using off-line and on-line SPE followed by LC coupled with DAD-MS. Chromatographia 2006, 64:13-21.
34. Kümmerer K. Antibiotics in the aquatic environment - a review - Part I. Chemosphere 2009, 75:417-434.
35. Le T.X., Munekage Y. Residues of selected antibiotics in water and mud from shrimp ponds in mangrove areas in Viet Nam. Mar. Pollut. Bull. 2004, 49:922-929.
36. Lindberg R.H., Olofsson U., Rendahl P., Johansson M.I., Tysklind M., Andersson B.A.V. Behavior of fluoroquinolones and trimethoprim during mechanical, chemical, and active sludge treatment of sewage water and digestion of sludge. Environ. Sci. Technol. 2006, 40:1042-1048.
37. Mompelat S., Le Bot B., Thomas O. Occurrence and fate of pharmaceutical products and by-products, from resource to drinking water. Environ. Int. 2009, 35:803-814.
38. Na G., Fang X., Cai Y., Ge L., Zong H., Yuan X., Yao Z., Zhang Z. Occurrence, distribution, and bioaccumulation of antibiotics in coastal environment of Dalian, China. Mar. Pollut. Bull. 2013, 69:233-237.
39. Nödler K., Voutsa D., Licha T. Polar organic micropollutants in the coastal environment of different marine systems. Mar. Pollut. Bull. 2014, 85:50-59.
40. Packer J.L., Werner J.J., Latch D.E., McNeill K., Arnold W.A. Photochemical fate of pharmaceuticals in the environment: naproxen, diclofenac, clofibric acid, and ibuprofen. Aquat. Sci. 2003, 65:342-351.
41. Park S., Choi K. Hazard assessment of commonly used agricultural antibiotics on aquatic ecosystems. Ecotoxicology 2008, 17:526-538.
42. Pomati F., Netting A.G., Calamari D., Neilan B.A. Effects of erythromycin, tetracycline and ibuprofen on the growth of Synechocystis sp. and Lemna minor. Aquat. Toxicol. 2004, 67:387-396.
43. R Core Team. R: A Language and Environment for Statistical Computing, 2014. Vienna: R Foundation for Statistical Computing.
44. Richardson M.L., Bowron J.M. The fate of pharmaceuticals in the aquatic environment. J. Pharm. Pharmacol. 1985, 37:1-12.
45. Robinson A.A., Belden J.B., Lydy M.J. Toxicity of fluoroquinolone antibiotics to aquatic organisms. Environ. Toxicol. Chem. 2005, 24:423-430.
46. Sarmah A.K., Meyer M.T., Boxall A.B.A. Review: a global perspective on the use, sales, exposure pathways, occurrence, fate and effects of veterinary antibiotics (VAs) in the environment. Chemosphere 2006, 65:725-759.
47. Siedlewicz G., Pazdro K., Borecka M., Kornowska K., Białk-Bielińska A., Stepnowski P. Determination of tetracyclines residues in the Gulf of Gdańsk (southern Baltic Sea) sediments using a tandem solid-phase extraction with liquid chromatography coupled with tandem mass spectrometry. GeoPlanet: Earth and Planetary Sciences, Insights on Environmental Changes, Where the World is Heading 2014, 33-48. Springer International Publishing, Switzerland. T. Zieliński (Ed.).
48. Straub J.O. An environmental risk assessment for human-use trimethoprim in European surface waters. Antibiotics 2013, 2:115-162.
49. Straub J.O., Stewart K.M. Deterministic and probabilistic acute-based environmental risk assessment for naproxen for Western Europe. Environ. Toxicol. Chem. 2007, 26:795-806.
50. Thomas K.V., Hilton M.J. The occurrence of selected human pharmaceutical compounds in UK estuaries. Mar. Pollut. Bull. 2004, 49:436-444.
51. Thurman E.M., Snavely K. Advances in solid-phase extraction disks for environmental chemistry. Trends Anal. Chem. 2000, 19:18-26.
52. Turiel E., Martín-Esteban A., Tadeo J.L. Multiresidue analysis of quinolones and fluoroquinolones in soil by ultrasonic-assisted extraction in small columns and HPLC-UV. Anal. Chim. Acta 2006, 562:30-35.
53. Vera-Candioti L., Gil Garcia M.D., Martinez Galera M., Goicoechea H.C. Chemometric assisted solid-phase microextraction for the determination of anti-inflammatory and antiepileptic drugs in river water by liquid chromatography-diode array detection. J. Chromatogr. A 2008, 1211:22-32.
54. Vulliet E., Cren-Olivé C. Screening of pharmaceuticals and hormones at regional scale, in surface and groundwaters intended to human consumption. Environ. Pollut. 2011, 159:2929-2934.
55. Weigel S., Kuhlmann J., Hühnerfuss H. Drugs and personal care products as ubiquitous pollutants: occurrence and distribution of clofibric acid, caffeine and DEET in the North Sea. Sci. Total Environ. 2002, 295:131-141.
56. Yang L.H., Ying G.G., Su H.C., Strauber J.L., Adams M.S., Binet M.T. Growth-inhibiting effects of 12 antibacterial agents and their mixtures on the freshwater microalga Pseudokirchneriella subcapitata. Environ. Toxicol. Chem. 2008, 27:1201-1208.
57. Zhang R., Zhang G., Zheng Q., Tang J., Chen Y., Xu W., Zou Y., Chen X. Occurrence and risks of antibiotics in the Laizhou Bay, China: impacts of river discharge. Ecotoxicol. Environ. Saf. 2012, 80:208-215.
58. Zheng Q., Zhang R., Wang Y., Pan X., Tang J., Zhang G. Occurrence and distribution of antibiotics in the Beibu Gulf, China: impacts of river discharge and aquaculture activities. Mar. Environ. Res. 2012, 78:26-33.