Ligands involved in conditioning may enhance the protection afforded by remote ischemia and reperfusion

International Journal of Cardiology

Volumn 190, Issue 1, 2015, Pages 273-274

  Andreadou, Ioanna ^a   Farmakis, Dimitrios ^b   Iliodromitis, Efstathios K ^b  

^a UNIVERSITY OF ATHENS   (Greece)

^b NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS   (Greece)

Author keywords

Cardioprotection; Morphine; Remote conditioning; RISK

Indexed keywords

ADENOSINE; BRADYKININ; CATECHOLAMINE; MORPHINE; NORADRENALIN; LIGAND; NARCOTIC ANALGESIC AGENT;

ACUTE CORONARY SYNDROME; BLOOD PRESSURE MEASUREMENT; BRAIN ISCHEMIA; CONDITIONING; CORONARY ARTERY DISEASE; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HUMAN; INTRACELLULAR SIGNALING; INTRAVASCULAR CATHETER; LETTER; NONHUMAN; PRIORITY JOURNAL; REMOTE ISCHEMIC CONDITIONING; REPERFUSION INJURY; THROMBOCYTE AGGREGATION; ANIMAL; HEART INFARCTION PREVENTION; HEART MUSCLE REPERFUSION; METABOLISM; MYOCARDIAL REPERFUSION INJURY; PROCEDURES;

ANALGESICS, OPIOID; ANIMALS; HUMANS; ISCHEMIC PRECONDITIONING, MYOCARDIAL; LIGANDS; MYOCARDIAL REPERFUSION; MYOCARDIAL REPERFUSION INJURY;

EID: 84929169718     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2015.04.203     Document Type: Article

References (10)

1. G. Heusch, Molecular basis of cardioprotection: signal transduction in ischemic pre-, post-, and remote conditioning, Circ. Res. 116 (2015) 674-699.
2. E.R. Gross, A.K. Hsu, G.J. Gross, GSK3beta inhibition and K(ATP) channel opening mediate acute opioid-induced cardioprotection at reperfusion, Basic Res. Cardiol. 102 (2007) 341-349.
3. I. Andreadou, E.K. Iliodromitis, M. Koufaki, D. Th. Kremastinos, Pharmacological preand post-conditioning agents: reperfusion-injury of the heart revisited, Mini Rev. Med. Chem. 8 (2008) 952-959.
4. Y. Lu, J. Hu, C. Dong, Morphine may enhance the cardioprotection induced by remote ischemic preconditioning, Int. J. Cardiol. 187 (2015) 443-444.
5. Y. Lu, C.S. Dong, J.M. Yu, H. Li, Morphine reduces the threshold of remote ischemic preconditioning against myocardial ischemia and reperfusion injury in rats: the role of opioid receptors, J. Cardiothorac. Vasc. Anesth. 26 (2012) 403.
6. J.E. Schultz, G.J. Gross, Opioids and cardioprotection, Pharmacol. Ther. 89 (2001) 123-137.
7. D.J. Hausenloy, E.K. Iliodromitis, I. Andreadou, A. Papalois, G. Gritsopoulos, M. Anastasiou-Nana, D.T. Kremastinos, D.M. Yellon, Investigating the signal transduction pathways underlying remote ischemic conditioning in the porcine heart, Cardiovasc. Drugs Ther. 26 (2012) 87-93.
8. I. Andreadou, S.-I. Bibli, E. Mastromanolis, A. Zoga, P. Efentakis, N. Papaioannou, D. Farmakis, DTh. Kremastinos, E.K. Iliodromitis, Transient carotid ischemia as a remote conditioning stimulus on myocardial infarction size in anesthetized rabbits: insights into the intracellular signaling, Int. J. Cardiol. 184C (2015) 140-151.
9. G. Gritsopoulos, E.K. Iliodromitis, A. Zoga, D. Farmakis, E. Demerouti, A. Papalois, I.A. Paraskevaidis, D.T. Kremastinos, Remote postconditioning is more potent than classic postconditioning in reducing the infarct size in anesthetized rabbits, Cardiovasc. Drugs Ther. 23 (2009) 193-198.
10. E.K. Iliodromitis, M.V. Cohen, N. Dagres, I. Andreadou, Kremastinos DTh, J.M. Downey, What is wrong with cardiac conditioning? We may be shooting at moving targets, J. Cardiovasc. Pharmacol. Ther. (2015) (pii: 1074248414566459) (in press).