Association between FokI, ApaI and TaqI RFLP polymorphisms in VDR gene and Hashimoto's thyroiditis: Preliminary data from female patients in Serbia

International Journal of Immunogenetics

Volumn 42, Issue 3, 2015, Pages 190-194

  Djurovic, J ^a   Stojkovic, O ^a   Ozdemir, O ^b,c   Silan, F ^c   Akurut, C ^c   Todorovic, J ^d   Savic, K ^a   Stamenkovic, G ^e  

^a UNIVERSITY OF BELGRADE   (Serbia)

^b CUMHURIYET UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

^c ÇANAKKALE ONSEKIZ MART UNIVERSITY   (Turkey)

^d Private Consulting Room 'Thyreomedicus'   (Serbia)

^e UNIVERSITY OF BELGRADE   (Serbia)

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA; VITAMIN D RECEPTOR; CALCITRIOL RECEPTOR;

ADULT; ALLELE; APAI GENE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FOKI GENE; GENE; GENE FREQUENCY; GENETIC ASSOCIATION; HAPLOTYPE; HASHIMOTO DISEASE; HUMAN; POPULATION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RESTRICTION MAPPING; SERBIA; TAQI GENE; VITAMIN D RECEPTOR GENE; GENETIC ASSOCIATION STUDY; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; ODDS RATIO; SEX DIFFERENCE;

ALLELES; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HASHIMOTO DISEASE; HUMANS; ODDS RATIO; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RECEPTORS, CALCITRIOL; SERBIA; SEX FACTORS;

EID: 84929165968     PISSN: 17443121     EISSN: 1744313X     Source Type: Journal    
DOI: 10.1111/iji.12199     Document Type: Article

References (41)

1. Adorini, L. & Penna, G. (2008) Control of autoimmune diseases by the vitamin D endocrine system. Nature Clinical Practice Rheumatology, 4, 404.
2. Antonelli, A., Ferrari, M.S., Corrado, A., Di Domenicantonio, A. & Fallahi, P. (2014) Autoimmune thyroid disorders. Autoimmunity Reviews, 14, 174.
3. Arai, H., Miyamoto, K., Taketani, Y., Yamamoto, H., Iemori, Y., Morita, K. et al. (1997) A vitamin D receptor gene polymorphism in the translation initiation codon: effect on protein activity and relation to bone mineral density in Japanese women. Journal of Bone and Mineral Research, 12, 915.
4. Ban, Y. & Taniyama, M. (2001) Vitamin D receptor gene polymorphisms in Hashimoto's thyroiditis. Thyroid, 11, 607.
5. Bhalla, A.K., Amento, E.P. & Krane, S.M. (1986) Differential effects of 1, 25-dihydroxyvitamin D3 on human lymphocytes and monocyte/macrophages: inhibition of interleukin-2 and augmentation of interleukin-1 production. Cellular Immunology, 98, 311.
6. Bozkurt, N.C., Karbek, B., Ucan, B., Sahin, M., Cakal, E., Ozbek, M. & Delibasi, T. (2013) The association between severity of vitamin D deficiency and Hashimoto's thyroiditis. Endocrine Practice, 19, 479.
7. Caturegli, P., De Remigis, A. & Rose, N.R. (2014) Hashimoto thyroiditis: clinical and diagnostic criteria. Autoimmunity Reviews, 13, 391.
8. Chistiakov, D.A. (2005) Immunogenetics of Hashimoto's thyroiditis. Journal of Autoimmune Diseases, 2, 1.
9. Denzer, N., Vogt, T. & Reichrath, J. (2011) Vitamin D receptor (VDR) polymorphisms and skin cancer: a systematic review. Dermatoendocrinol, 3, 205.
10. Dusso, A.S., Brown, A.J. & Slatopolsky, E. (2005) Vitamin D. American Journal of Physiology. Renal Physiology, 289, F8.
11. Ferrarezi, D.A., Bellili-Munoz, N., Dubois-Laforgue, D., Cheurfa, N., Lamri, A., Reis, A.F. et al. (2013) Allelic variations of the vitamin D receptor (VDR) gene are associated with increased risk of coronary artery disease in type 2 diabetics: the DIABHYCAR prospective study. Diabetes & Metabolism, 39, 263.
12. Ferrari, S., Rizzoli, R., Manen, D., Slosman, D. & Bonjour, J.P. (1998) Vitamin D receptor gene start codon polymorphisms (FokI) and bone mineral density: interaction with age, dietary calcium, and 3'-end region polymorphisms. Journal of Bone and Mineral Research, 13, 925.
13. Fournier, C., Gepner, P., Sadouk, M. & Charreire, J. (1990) In vivo beneficial effects of cyclosporin A and 1, 25-dihydroxyvitamin D3 on the induction of experimental autoimmune thyroiditis. Clinical Immunology and Immunopathology, 54, 53.
14. Haussler, M.R., Whitfield, G.K., Haussler, C.A., Hsieh, J.C., Thompson, P.D., Selznick, S.H., Dominguez, C.E. & Jurutka, P.W. (1998) The nuclear vitamin D receptor: biological and molecular regulatory properties revealed. Journal of Bone and Mineral Research, 13, 325.
15. Haussler, M.R., Haussler, C.A., Bartik, L., Whitfield, G.K., Hsieh, J.C., Slater, S. & Jurutka, P.W. (2008) Vitamin D receptor: molecular signaling and actions of nutritional ligands in disease prevention. Nutrition Reviews, 66, S98.
16. Heine, G., Hoefer, N., Franke, A., Nothling, U., Schumann, R.R., Hamann, L. & Worm, M. (2013) Association of vitamin D receptor gene polymorphisms with severe atopic dermatitis in adults. British Journal of Dermatology, 168, 855.
17. Jurutka, P.W., Remus, L.S., Whitfield, G.K., Thompson, P.D., Hsieh, J.C., Zitzer, H. et al. (2000) The polymorphic N terminus in human vitamin D receptor isoforms influences transcriptional activity by modulating interaction with transcription factor IIB. Molecular Endocrinology, 14, 401.
18. Kaabachi, W., Kaabachi, S., Rafrafi, A., Amor, A.B., Tizaoui, K., Haj Sassi, F. & Hamzaoui, K. (2014) Association of vitamin D receptor FokI and ApaI polymorphisms with lung cancer risk in Tunisian population. Molecular Biology Reports, 41, 6545.
19. Kamen, D.L. & Tangpricha, V. (2010) Vitamin D and molecular actions on the immune system: modulation of innate and autoimmunity. Journal of Molecular Medicine (Berlin), 88, 441.
20. Kanan, R.M. (2013) The effect of FokI vitamin D receptor polymorphism on bone mineral density in Jordanian perimenopausal women. Indian Journal of Human Genetics, 19, 233.
21. Kivity, S., Agmon-Levin, N., Zisappl, M., Shapira, Y., Nagy, E.V., Danko, K., Szekanecz, Z., Langevitz, P. & Shoenfeld, Y. (2011) Vitamin D and autoimmune thyroid diseases. Cellular & Molecular Immunology, 8, 243.
22. Kostner, K., Denzer, N., Muller, C.S., Klein, R., Tilgen, W. & Reichrath, J. (2009) The relevance of vitamin D receptor (VDR) gene polymorphisms for cancer: a review of the literature. Anticancer Research, 29, 3511.
23. Lee, Y.H. & Song, G.G. (2014) Vitamin D receptor FokI, BsmI, ApaI, and TaqI polymorphisms and the susceptibility to breast cancer: a meta-analysis. Neoplasma, 61, 607.
24. Lemire, J.M., Adams, J.S., Sakai, R. & Jordan, S.C. (1984) 1 alpha, 25-dihydroxyvitamin D3 suppresses proliferation and immunoglobulin production by normal human peripheral blood mononuclear cells. Journal of Clinical Investigation, 74, 657.
25. Lin, W.Y., Wan, L., Tsai, C.H., Chen, R.H., Lee, C.C. & Tsai, F.J. (2006) Vitamin d receptor gene polymorphisms are associated with risk of Hashimoto's thyroiditis in Chinese patients in Taiwan. Journal of Clinical Laboratory Analysis, 20, 109.
26. Mathieu, C., Laureys, J., Sobis, H., Vandeputte, M., Waer, M. & Bouillon, R. (1992) 1, 25-dihydroxyvitamin D3 prevents insulitis in nod mice. Diabetes, 41, 1491.
27. Morrison, N.A., Qi, J.C., Tokita, A., Kelly, P.J., Crofts, L., Nguyen, T.V., Sambrook, P.N. & Eisman, J.A. (1994) Prediction of bone density from vitamin D receptor alleles. Nature, 367, 284.
28. Raby, B.A., Lazarus, R., Silverman, E.K., Lake, S., Lange, C., Wjst, M. & Weiss, S.T. (2004) Association of vitamin D receptor gene polymorphisms with childhood and adult asthma. American Journal of Respiratory and Critical Care Medicine, 170, 1057.
29. Reichel, H., Koeffler, H.P., Tobler, A. & Norman, A.W. (1987) 1 alpha, 25-dihydroxyvitamin D3 inhibits gamma-interferon synthesis by normal human peripheral blood lymphocytes. Proceedings of the National Academy of Sciences of the United States of America, 84, 3385.
30. Rigby, W.F., Stacy, T. & Fanger, M.W. (1984) Inhibition of T lymphocyte mitogenesis by 1, 25-dihydroxyvitamin D3 (calcitriol). Journal of Clinical Investigation, 74, 1451.
31. Stefanic, M., Papic, S., Suver, M., Glavas-Obrovac, L. & Karner, I. (2008) Association of vitamin D receptor gene 3'-variants with Hashimoto's thyroiditis in the Croatian population. International Journal of Immunogenetics, 35, 125.
32. Topaloglu, N., Oguz, S., Silan, F., Uludag, A., Isik, S. & Akurut, C. (2014) Association of vitamin D receptor gene polymorphisms in children with atopic diseases. Gene Therapy and Molecular Biology, 16, 55.
33. Toubi, E. & Shoenfeld, Y. (2010) The role of vitamin D in regulating immune responses. The Israel Medical Association Journal, 12, 174.
34. Uitterlinden, A.G., Fang, Y., Van Meurs, J.B., Pols, H.A. & Van Leeuwen, J.P. (2004) Genetics and biology of vitamin D receptor polymorphisms. Gene, 338, 143.
35. Vacca, A., Cormier, C., Piras, M., Mathieu, A., Kahan, A. & Allanore, Y. (2009) Vitamin D deficiency and insufficiency in 2 independent cohorts of patients with systemic sclerosis. Journal of Rheumatology, 36, 1924.
36. Van Etten, E., Verlinden, L., Giulietti, A., Ramos-Lopez, E., Branisteanu, D.D., Ferreira, G.B., et al. (2007) The vitamin D receptor gene FokI polymorphism: functional impact on the immune system. European Journal of Immunology, 37, 395.
37. Vanderpump, M.P. & Tunbridge, W.M. (2002) Epidemiology and prevention of clinical and subclinical hypothyroidism. Thyroid, 12, 839.
38. Wang, C. & Crapo, L.M. (1997) The epidemiology of thyroid disease and implications for screening. Endocrinology and Metabolism Clinics of North America, 26, 189.
39. Whitfield, G.K., Remus, L.S., Jurutka, P.W., Zitzer, H., Oza, A.K., Dang, H.T. et al. (2001) Functionally relevant polymorphisms in the human nuclear vitamin D receptor gene. Molecular and Cellular Endocrinology, 177, 145.
40. Zhang, Y., Gao, Y., Li, M., Xie, L., Huang, Y. & Guo, X. (2010) Avidity of thyroglobulin antibody in sera from patients with Hashimoto's thyroiditis with different thyroid functional status. Clinical and Experimental Immunology, 161, 65.
41. Zhou, X., Xu, L.D. & Li, Y.Z. (2014) The association of polymorphisms of the vitamin D receptor gene with psoriasis in the Han population of northeastern China. Journal of Dermatological Science, 73, 63.