Accidental human poisoning with a neonicotinoid insecticide, imidacloprid: A rare case report from rural India with a brief review of literature

Egyptian Journal of Forensic Sciences

Volumn 3, Issue 4, 2013, Pages 123-126

  Kumar, Alok ^a   Verma, Archana ^b   Kumar, Adarsh ^c  

^a Forensic Medicine and Toxicology UP Regional Institute of Medical Sciences and Research   (India)

^b Neurology UP Regional Institute of Medical Sciences and Research   (India)

^c ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Imidacloprid; Inhalation; Insecticide; Neonicotinoids; Pesticide; Poisoning

Indexed keywords

EID: 84929141942     PISSN: 2090536X     EISSN: 20905939     Source Type: Journal    
DOI: 10.1016/j.ejfs.2013.05.002     Document Type: Article

References (29)

1. U.S. EPA office of pesticide programs. Pesticide fact sheet. Imidacloprid 1994;18:1.
2. Toxic effects of pesticides, In: Doull J, Klassen CD, Amdur MO, editors. Cassarett and Doull's toxicology: the basic science of poisons. 4th ed. NY: Pergamon Press; 1991. p. 889-93.
3. Hovda L.R., Hooser S.B. Toxicology of newer pesticides for use in dogs and cats. Vet Clin Small Anim 2002, 32:455-467.
4. Motohiro T., Casida J.E. Neonicotinoid insecticide toxicology: mechanisms of selective action. Rev Lit Arts Am 2005, 45:247-268.
5. Tomlin C.D.S. The pesticide manual, a world compendium 2006, British Crop Protection Council, Surry, England, p. 598-9. 14th ed.
6. Fossen M. Environmental fate of imidiacloprid. 3rd ed. Sacramento, CA: Department of Pesticide Regulation, Environmental Monitoring; 2006.
7. Buckingham S.D., Lapied B., Corronc H.L., Grolleau F., Sattelle D.B. Imidacloprid actions on insect neuronal acetylcholine receptors. J Exp Biol 1997, 200:2685-2692.
8. Matsuda K., Sattelle D.B. Mechanism of selective actions of neonicotinoids on insect acetylcholine receptors. New discoveries in agrochemicals: American chemical society symposium series 2005, 172-183. Oxford University Press, Oxford, UK. 3rd ed. J.M. Clark, H. Ohkawa (Eds.).
9. Schroeder M.E., Flattum R.F. The mode of action and neurotoxic properties of the nitroethylene heterocycle insecticides. Pestic Biochem Physiol 1984, 22:148-160.
10. Sheets L.P. Imidacloprid: a neonicotinoid insecticide. Handbook of pesticide toxicology 2001, 1123-1130. Academic Press, San Diego, CA. 2nd ed. R.I. Krieger (Ed.).
11. Tomizawa M., Casida J.E. Minor structural changes in nicotinic insecticides confer differential subtype selectivity for mammalian nicotinic acetylcholine receptors. Br J Pharmacol 1999, 127(1):115-122.
12. Wismer T. Novel insecticides. Clinical veterinary toxicology 2004, 184-185. Mosby, St. Louis, MO. K.H. Plumlee (Ed.).
13. Label review manual; U.S. environmental protection agency, Office of prevention, pesticides and toxic substances, Office of pesticide programs.
14. Gervais JA, Luukinen B, Buhl K, Stone D. Imidacloprid technical factsheet. National Pesticide Information Centre, Oregon State University Extension Services. Available at www.npic.orst.edu/factsheets/imidaclorpid.pdfaccessed 28.08.12.
15. Thyssen J., Machemer L. Imidacloprid toxicology and metabolism. Nicotinoid insecticides and the nicotinic acetylcholine receptor 1999, 213-222. Springer-Verlag, Tokyo. I. Yamamoto, J.E. Casida (Eds.).
16. Sheets LP. The neonicotinoid insecticides. In: Massaro EJ, editor. Handbook of neurotoxicology, vol. 1. Totowa, New Jer-sey: Humana Press; 2002. p. 79-87 chapter 6.
17. Wu I., Lin J., Cheng E. Acute poisoning with the neonicotinoid insecticide imidacloprid in N-methyl pyrrolidone. Clin Toxicol 2001, 39(6):617-621.
18. Shadnia S., Moghaddam H.H. Fatal intoxication with imidacloprid insecticide. Am J Emerg Med 2008, 26(5):634.
19. Huang N., Lin S., Chou C., Hung Y., Chung H., Huang S. Fatal ventricular fibrillation in a patient with acute imidacloprid poisoning. Am J Emerg Med 2006, 24(7):883-885.
20. Agarwal R., Srinivas R. Severe neuropsychiatric manifestations and rhabdomyolysis in a patient with imidacloprid poisoning. Am J Emerg Med 2007, 25(7):844-845.
21. Pesticide residues in food - 2000. Report of the joint meeting of the FAO panel of experts on pesticide residues in food and the environment and the WHO core assessment group. FAO plant production and protection paper 167.
22. Brunet J., Maresca M., Fantini J., Belzunces L.P. Human intestinal absorption of imidacloprid with CaCO-2 cells as entercyte model. Toxicol Appl Pharmacol 2004, 194(1):1-9.
23. Klein O. Investigations on the distribution of the total radioactivity in the rat by whole body autoradiography. Unpublished report no. PF2891, 1987, submitted to WHO by Bayer AG, Mannheim, Germany. INCHEM Toxicological Evaluations: Imidacloprid; International Programme on Chemical Safety, World Health Organization: Geneva, Switzerland, 1987.
24. Tomizawa M., Casida J.E. Neonicotinoid insecticide toxicology: mechanisms of selective action. Annu Rev Pharmacol Toxicol 2005, 45:247-268.
25. Mohamed F, Gawarammana I, Robertson TA, Roberts MS, Palangasinghe C, Shukry Z, et al. Acute human self-poisoning with imidacloprid compound: a neonicotinoid insecticide. Available online at http://www.plosone.org/article/info%3Adoi/ 10.1371/journal.pone.0005127 accessed 30.08.12.
26. Kumar A., Verma A., Jaiswal K., Kumar S., Prasad R. Emergence of entirely new poisoning in rural India; an upcoming health hazard to the community health. Indian J Community Health 2012, 24(3):248-251.
27. Zwart R., Marga O., Henk P.M. Nitromethylene heterocycles: selective agonists of nicotinic receptors in locust neurons compared to mouse N1E-115 and BC3H1 cells. Pest Biochem Physiol 1994, 48:202-213.
28. Rao C., Venkateswarlu V., Surender T., Eddleston M., Buckley N.A. Pesticide poisoning in south India - opportunities for prevention and improved medical management. Trop Med Int Health 2005, 10:581-588.
29. Eddleston M., Eyer P., Worek F., Mohamed F., Senarathna L., von Meyer L., et al. Differences between organophosphorus insecticides in human self-poisoning: a prospective cohort study. Lancet 2005, 366:1452-1459.