Minor structural changes in nicotinoid insecticides confer differential subtype selectivity for mammalian nicotinic acetylcholine receptors

British Journal of Pharmacology

Volumn 127, Issue 1, 1999, Pages 115-122

  Tomizawa, Motohiro ^a   Casida, John E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

86Rb+ efflux; Chloropyridinyl nicotinic ligands; Human neuroblastoma SH SY5Y cells; Imidacloprid; Nicotinic AChR subtypes; Nicotinoid insecticides

Indexed keywords

IMIDACLOPRID; INSECTICIDE; NICOTINE; NICOTINIC RECEPTOR; RECEPTOR SUBTYPE; RUBIDIUM 86;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG RECEPTOR BINDING; HUMAN; HUMAN CELL; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MOUSE; NEUROBLASTOMA; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTIBODIES, MONOCLONAL; CHOLINERGIC AGENTS; ELECTRIC ORGAN; HUMANS; IMIDAZOLES; INSECTICIDES; MICE; NICOTINE; NICOTINIC AGONISTS; RADIOLIGAND ASSAY; RATS; RECEPTORS, NICOTINIC; RUBIDIUM RADIOISOTOPES; STRUCTURE-ACTIVITY RELATIONSHIP; TORPEDO; TUMOR CELLS, CULTURED;

EID: 0032904374     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702526     Document Type: Article

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