Nanoparticles and antigen-specific T-cell therapeutics: A comprehensive study on uptake and release

Nanomedicine

Volumn 10, Issue 7, 2015, Pages 1063-1076

  Zupke, Oliver ^a,b   Distler, Eva ^a   Jürchott, Anna ^a   Paiphansiri, Umaporn ^c   Dass, Martin ^c   Thomas, Simone ^a,d   Hartwig, Udo F ^a   Theobald, Matthias ^a   Landfester, Katharina ^c   Mailänder, Volker ^a,c   Herr, Wolfgang ^a,d  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b INSTITUT FÜR MIKROTECHNIK MAINZ GMBH   (Germany)

^c MAX PLANCK INSTITUTE FOR POLYMER RESEARCH   (Germany)

^d UNIVERSITY HOSPITAL REGENSBURG   (Germany)

Author keywords

cell imaging; cellular therapy; drug delivery; endocytosis; leukemia; nanoparticles; NP release; T lymphocytes; tumor

Indexed keywords

GAMMA INTERFERON; NANOPARTICLE; DRUG CARRIER; POLYMER;

ANTIGEN SPECIFICITY; ARTICLE; CELL SURFACE; CELL THERAPY; CHROMIUM RELEASE ASSAY; CONFOCAL LASER MICROSCOPY; CYTOTOXIC T LYMPHOCYTE; DRUG RELEASE; DRUG RETENTION; DRUG SYNTHESIS; DRUG UPTAKE; ENZYME LINKED IMMUNOSPOT ASSAY; FLOW CYTOMETRY; IN VITRO STUDY; IN VIVO STUDY; POLYMERIZATION; PRIORITY JOURNAL; T CELL CULTURE; T LYMPHOCYTE; TRANSMISSION ELECTRON MICROSCOPY; VIRUS PARTICLE; ANIMAL; C57BL MOUSE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL LINE; CHEMISTRY; CONFOCAL MICROSCOPY; DRUG DELIVERY SYSTEM; DRUG EFFECTS; ENDOCYTOSIS; HUMAN; METABOLISM; ULTRASTRUCTURE;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL LINE; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; DRUG LIBERATION; ENDOCYTOSIS; HUMANS; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; POLYMERS;

EID: 84929104620     PISSN: 17435889     EISSN: 17486963     Source Type: Journal    
DOI: 10.2217/nnm.14.160     Document Type: Article

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