-
1
-
-
0023161666
-
T-cell unresponsiveness in vivo and in vitro: Fine specificity of induction and molecular characterization of the unresponsive state
-
MK Jenkins DM Pardoll J Mizuguchi H Quill RH Schwartz 1987 T-cell unresponsiveness in vivo and in vitro: fine specificity of induction and molecular characterization of the unresponsive state Immunol Rev 95 113 135 2437012 10.1111/j.1600-065X.1987.tb00502.x 1:CAS:528:DyaL2sXhvFCitbo%3D (Pubitemid 17027899)
-
(1987)
Immunological Reviews
, vol.95
, pp. 113-135
-
-
Jenkins, M.K.1
Pardoll, D.M.2
Mizuguchi, J.3
-
2
-
-
0026335737
-
Antigen-specific therapy of experimental allergic encephalomyelitis by soluble class II major histocompatibility complex-peptide complexes
-
SD Sharma B Nag XM Su D Green E Spack BR Clark S Sriram 1991 Antigen-specific therapy of experimental allergic encephalomyelitis by soluble class II major histocompatibility complex-peptide complexes Proc Natl Acad Sci USA 88 11465 11469 1722335 10.1073/pnas.88.24.11465 1:CAS:528: DyaK38Xlslahuw%3D%3D (Pubitemid 21916062)
-
(1991)
Proceedings of the National Academy of Sciences of the United States of America
, vol.88
, Issue.24
, pp. 11465-11469
-
-
Sharma, S.D.1
Nag, B.2
Xiao-Min, S.3
Green, D.4
Spack, E.5
Clark, B.R.6
Sriram, S.7
-
3
-
-
0029972878
-
Soluble MHC II-peptide complexes induce antigen-specific apoptosis in T cells
-
10.1006/cimm.1996.0130 8660796 10.1006/cimm.1996.0130 1:CAS:528:DyaK28XjtlaitLg%3D
-
B Nag T Kendrick S Arimilli SC Yu S Sriram 1996 Soluble MHC II-peptide complexes induce antigen-specific apoptosis in T cells Cell Immunol 170 25 33 10.1006/cimm.1996.0130 8660796 10.1006/cimm.1996.0130 1:CAS:528: DyaK28XjtlaitLg%3D
-
(1996)
Cell Immunol
, vol.170
, pp. 25-33
-
-
Nag, B.1
Kendrick, T.2
Arimilli, S.3
Yu, S.C.4
Sriram, S.5
-
4
-
-
0030006047
-
Functionally active recombinant α and β chain-peptide complexes of human major histocompatibility class II molecules
-
DOI 10.1074/jbc.271.17.10413
-
B Nag S Arimilli PV Mukku I Astafieva 1996 Functionally active recombinant alpha and beta chain-peptide complexes of human major histocompatibility class II molecules J Biol Chem 271 10413 10418 8626615 10.1074/jbc.271.17.10413 1:CAS:528:DyaK28XisFKjtr8%3D (Pubitemid 26131608)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.17
, pp. 10413-10418
-
-
Nag, B.1
Arimilli, S.2
Mukku, P.V.3
Astafieva, I.4
-
5
-
-
0029874256
-
Antigen-specific apoptosis in immortalized T cells by soluble MHC class II-peptide complexes
-
S Arimilli JB Mumm B Nag 1996 Antigen-specific apoptosis in immortalized T cells by soluble MHC class II-peptide complexes Immunol Cell Biol 74 96 104 10.1038/icb.1996.13 8934660 10.1038/icb.1996.13 1:CAS:528:DyaK28XislGqurs%3D (Pubitemid 26150505)
-
(1996)
Immunology and Cell Biology
, vol.74
, Issue.1
, pp. 96-104
-
-
Arimilli, S.1
Mumm, J.B.2
Nag, B.3
-
6
-
-
0034636191
-
84-102 (AG284) in multiple sclerosis
-
DE Goodkin M Shulman J Winkelhake E Waubant P Andersson T Stewart S Nelson N Fischbein PK Coyle E Frohman L Jacobs J Holcenberg M Lee S Mocci 2000 A phase I trial of solubilized DR2:MBP84-102 (AG284) in multiple sclerosis Neurology 54 1414 1420 10751249 1:CAS:528:DC%2BD3cXivFOitLc%3D (Pubitemid 30210458)
-
(2000)
Neurology
, vol.54
, Issue.7
, pp. 1414-1420
-
-
Goodkin, D.E.1
Shulman, M.2
Winkelhake, J.3
Waubant, E.4
Andersson, P.-B.5
Stewart, T.6
Nelson, S.7
Fischbein, N.8
Coyle, P.K.9
Frohman, E.10
Jacobs, L.11
Holcenberg, J.12
Lee, M.13
Mocci, S.14
-
7
-
-
0027216428
-
An in vitro model for disease-specific immunotherapy in Myasthenia gravis using soluble MHC class II bound to AChR-derived peptide
-
MW Nicolle A Vincent S Sharma B Nag N Willcox J Newsom-Davis 1993 An in vitro model for disease-specific immunotherapy in myasthenia gravis using soluble MHC class II bound to AChR-derived peptide Ann NY Acad Sci 681 577 580 8357203 10.1111/j.1749-6632.1993.tb22946.x 1:CAS:528:DyaK3sXlsFyju74%3D (Pubitemid 23233883)
-
(1993)
Annals of the New York Academy of Sciences
, vol.681
, pp. 577-580
-
-
Nicolle, M.W.1
Vincent, A.2
Sharma, S.3
Nag, B.4
Willcox, N.5
Newsom-Davis, J.6
-
8
-
-
0028316255
-
Specific tolerance to an acetylcholine receptor epitope induced in vitro in myasthenia gravis CD4+ lymphocytes by soluble major histocompatibility complex class II-peptide complexes
-
10.1172/JCI117112 7512979 10.1172/JCI117112 1:CAS:528:DyaK2cXis1yjtbc%3D
-
MW Nicolle B Nag SD Sharma N Willcox A Vincent DJ Ferguson J Newsom-Davis 1994 Specific tolerance to an acetylcholine receptor epitope induced in vitro in myasthenia gravis CD4+ lymphocytes by soluble major histocompatibility complex class II-peptide complexes J Clin Invest 93 1361 1369 10.1172/JCI117112 7512979 10.1172/JCI117112 1:CAS:528:DyaK2cXis1yjtbc%3D
-
(1994)
J Clin Invest
, vol.93
, pp. 1361-1369
-
-
Nicolle, M.W.1
Nag, B.2
Sharma, S.D.3
Willcox, N.4
Vincent, A.5
Ferguson, D.J.6
Newsom-Davis, J.7
-
9
-
-
0031940941
-
Diverse patterns of unresponsiveness in an acetylcholine receptor- specific T-cell clone from a myasthenia gravis patient after engaging the T- cell receptor with three different ligands
-
DOI 10.1016/S0165-5728(97)00202-6, PII S0165572897002026
-
AP Bond L Corlett SJ Curnow E Spack N Willcox J Newsom-Davis 1998 Diverse patterns of unresponsiveness in an acetylcholine receptor-specific T-cell clone from a myasthenia gravis patient after engaging the T-cell receptor with three different ligands J Neuroimmunol 82 182 190 9585815 10.1016/S0165-5728(97)00202- 6 1:CAS:528:DyaK1cXhvFKisL4%3D (Pubitemid 28179921)
-
(1998)
Journal of Neuroimmunology
, vol.82
, Issue.2
, pp. 182-190
-
-
Bond, A.P.1
Corlett, L.2
Curnow, S.J.3
Spack, E.4
Willcox, N.5
Newsom-Davis, J.6
-
10
-
-
0029587566
-
Induction of tolerance in experimental autoimmune myasthenia gravis with solubilized MHC class II: Acetylcholine receptor peptide complexes
-
DOI 10.1016/S0896-8411(95)80018-2
-
EG Spack M McCutcheon N Corbelletta B Nag D Passmore SD Sharma 1995 Induction of tolerance in experimental autoimmune myasthenia gravis with solubilized MHC class II:acetylcholine receptor peptide complexes J Autoimmun 8 787 807 8824707 10.1016/S0896-8411(95)80018-2 1:STN:280:DyaK28vit1Sqsg%3D%3D (Pubitemid 26046547)
-
(1995)
Journal of Autoimmunity
, vol.8
, Issue.6
, pp. 787-807
-
-
Spack, E.G.1
McCutcheon, M.2
Corbelletta, N.3
Nag, B.4
Passmore, D.5
Sharma, S.D.6
-
11
-
-
0037334236
-
Allele and antigen-specific treatment of rheumatoid arthritis: A double blind, placebo controlled phase trial
-
A Kavanaugh M Genovese J Baughman A Kivitz K Bulpitt N Olsen M Weisman E Matteson D Furst R van Vollenhoven J Anderson S Cohen N Wei J Meijerink C Jacobs S Mocci 2003 Allele and antigen-specific treatment of rheumatoid arthritis: a double blind, placebo controlled phase 1 trial J Rheumatol 30 449 454 12610799 1:CAS:528:DC%2BD3sXisVKgsr8%3D (Pubitemid 36301932)
-
(2003)
Journal of Rheumatology
, vol.30
, Issue.3
, pp. 449-454
-
-
Kavanaugh, A.1
Genovese, M.2
Baughman, J.3
Kivitz, A.4
Bulpitt, K.5
Olsen, N.6
Weisman, M.7
Matteson, E.8
Furst, D.9
Van Vollenhoven, R.10
Anderson, J.11
Cohen, S.12
Wei, N.13
Meijerink, J.14
Jacobs, C.15
Mocci, S.16
-
12
-
-
0030704726
-
+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
-
DOI 10.1038/39614
-
H Groux A O'Garra M Bigler M Rouleau S Antonenko JE de Vries MG Roncarolo 1997 A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis Nature 389 737 742 10.1038/39614 9338786 10.1038/39614 1:CAS:528:DyaK2sXmvVSgtb0%3D (Pubitemid 27458961)
-
(1997)
Nature
, vol.389
, Issue.6652
, pp. 737-742
-
-
Groux, H.1
O'Garra, A.2
Bigler, M.3
Rouleau, M.4
Antonenko, S.5
De Vries, J.E.6
Roncarolo, M.G.7
-
13
-
-
0031821875
-
+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
-
DOI 10.1084/jem.188.2.287
-
AM Thornton EM Shevach 1998 CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production J Exp Med 188 287 296 9670041 10.1084/jem.188.2.287 1:CAS:528:DyaK1cXkvVaqt7g%3D (Pubitemid 28357757)
-
(1998)
Journal of Experimental Medicine
, vol.188
, Issue.2
, pp. 287-296
-
-
Thornton, A.M.1
Shevach, E.M.2
-
14
-
-
0032402243
-
Two-domain MHC class II molecules form stable complexes with myelin basic protein 69-89 peptide that detect and inhibit rat encephalitogenic t cells and treat experimental autoimmune encephalomyelitis
-
GG Burrows BF Bebo Jr KL Adlard AA Vandenbark H Offner 1998 Two-domain MHC class II molecules form stable complexes with myelin basic protein 69-89 peptide that detect and inhibit rat encephalitogenic T cells and treat experimental autoimmune encephalomyelitis J Immunol 161 5987 5996 9834080 1:CAS:528:DyaK1cXnslCrsbk%3D (Pubitemid 28535967)
-
(1998)
Journal of Immunology
, vol.161
, Issue.11
, pp. 5987-5996
-
-
Burrows, G.G.1
Bebo Jr., B.F.2
Adlard, K.L.3
Vandenbark, A.A.4
Offner, H.5
-
15
-
-
0032824530
-
Design, engineering and production of functional single-chain T cell receptor ligands
-
GG Burrows JW Chang HP Bachinger DN Bourdette H Offner AA Vandenbark 1999 Design, engineering and production of functional single-chain T cell receptor ligands Protein Eng 12 771 778 10506287 10.1093/protein/12.9.771 1:CAS:528:DyaK1MXmvVagtro%3D (Pubitemid 29472084)
-
(1999)
Protein Engineering
, vol.12
, Issue.9
, pp. 771-778
-
-
Burrows, G.G.1
Chang, J.W.2
Bachinger, H.-P.3
Bourdette, D.N.4
Offner, H.5
Vandenbark, A.A.6
-
16
-
-
0034660502
-
Regulation of encephalitogenic T cells with recombinant TCR ligands
-
GG Burrows KL Adlard BF Bebo Jr JW Chang K Tenditnyy AA Vandenbark H Offner 2000 Regulation of encephalitogenic T cells with recombinant TCR ligands J Immunol 164 6366 6371 10843691 1:CAS:528:DC%2BD3cXktFWlt7k%3D (Pubitemid 30408818)
-
(2000)
Journal of Immunology
, vol.164
, Issue.12
, pp. 6366-6371
-
-
Burrows, G.G.1
Adlard, K.L.2
Bebo Jr., B.F.3
Chang, J.W.4
Tenditnyy, K.5
Vandenbark, A.A.6
Offner, H.7
-
17
-
-
64849084182
-
Cytokine switch and bystander suppression of autoimmune responses to multiple antigens in experimental autoimmune encephalomyelitis by a single recombinant T-cell receptor ligand
-
10.1523/JNEUROSCI.5812-08.2009 19321778 10.1523/JNEUROSCI.5812-08.2009 1:CAS:528:DC%2BD1MXktVSqtLY%3D
-
S Sinha S Subramanian L Miller TM Proctor C Roberts GG Burrows AA Vandenbark H Offner 2009 Cytokine switch and bystander suppression of autoimmune responses to multiple antigens in experimental autoimmune encephalomyelitis by a single recombinant T-cell receptor ligand J Neurosci 29 3816 3823 10.1523/JNEUROSCI.5812-08.2009 19321778 10.1523/JNEUROSCI.5812-08.2009 1:CAS:528:DC%2BD1MXktVSqtLY%3D
-
(2009)
J Neurosci
, vol.29
, pp. 3816-3823
-
-
Sinha, S.1
Subramanian, S.2
Miller, L.3
Proctor, T.M.4
Roberts, C.5
Burrows, G.G.6
Vandenbark, A.A.7
Offner, H.8
-
18
-
-
33748129891
-
Antigen-specific therapy promotes repair of myelin and axonal damage in established EAE
-
DOI 10.1111/j.1471-4159.2006.04081.x
-
C Wang BG Gold LJ Kaler X Yu ME Afentoulis GG Burrows AA Vandenbark DN Bourdette H Offner 2006 Antigen-specific therapy promotes repair of myelin and axonal damage in established EAE J Neurochem 98 1817 1827 10.1111/j.1471-4159. 2006.04081.x 16899071 10.1111/j.1471-4159.2006.04081.x 1:CAS:528: DC%2BD28XhtVCksb7M (Pubitemid 44313640)
-
(2006)
Journal of Neurochemistry
, vol.98
, Issue.6
, pp. 1817-1827
-
-
Wang, C.1
Gold, B.G.2
Kaler, L.J.3
Yu, X.4
Afentoulis, M.E.5
Burrows, G.G.6
Vandenbark, A.A.7
Bourdette, D.N.8
Offner, H.9
-
19
-
-
24744452162
-
Treatment of passive experimental autoimmune encephalomyelitis in SJL mice with a recombinant TCR ligand induces IL-13 and prevents axonal injury
-
H Offner S Subramanian C Wang M Afentoulis AA Vandenbark J Huan GG Burrows 2005 Treatment of passive experimental autoimmune encephalomyelitis in SJL mice with a recombinant TCR ligand induces IL-13 and prevents axonal injury J Immunol 175 4103 4111 16148160 1:CAS:528:DC%2BD2MXpslCltrc%3D (Pubitemid 41292074)
-
(2005)
Journal of Immunology
, vol.175
, Issue.6
, pp. 4103-4111
-
-
Offner, H.1
Subramanian, S.2
Wang, C.3
Afentoulis, M.4
Vandenbark, A.A.5
Huan, J.6
Burrows, G.G.7
-
20
-
-
12144289376
-
Monomeric Recombinant TCR Ligand Reduces Relapse Rate and Severity of Experimental Autoimmune Encephalomyelitis in SJL/J Mice through Cytokine Switch
-
J Huan S Subramanian R Jones C Rich J Link J Mooney DN Bourdette AA Vandenbark GG Burrows H Offner 2004 Monomeric recombinant TCR ligand reduces relapse rate and severity of experimental autoimmune encephalomyelitis in SJL/J mice through cytokine switch J Immunol 172 4556 4566 15034073 1:CAS:528:DC%2BD2cXitlOqtbw%3D (Pubitemid 38375273)
-
(2004)
Journal of Immunology
, vol.172
, Issue.7
, pp. 4556-4566
-
-
Huan, J.1
Subramanian, S.2
Jones, R.3
Rich, C.4
Link, J.5
Mooney, J.6
Bourdette, D.N.7
Vandenbark, A.A.8
Burrows, G.G.9
Offner, H.10
-
21
-
-
33947152923
-
Monomeric DR2/MOG-35-55 recombinant TCR ligand treats relapses of experimental encephalomyelitis in DR2 transgenic mice
-
DOI 10.1016/j.clim.2006.12.002, PII S1521661606009673
-
JM Link CM Rich M Korat GG Burrows H Offner AA Vandenbark 2007 Monomeric DR2/MOG-35-55 recombinant TCR ligand treats relapses of experimental encephalomyelitis in DR2 transgenic mice Clin Immunol 123 95 104 10.1016/j.clim.2006.12.002 17257899 10.1016/j.clim.2006.12.002 1:CAS:528:DC%2BD2sXjtValtbo%3D (Pubitemid 46401509)
-
(2007)
Clinical Immunology
, vol.123
, Issue.1
, pp. 95-104
-
-
Link, J.M.1
Rich, C.M.2
Korat, M.3
Burrows, G.G.4
Offner, H.5
Vandenbark, A.A.6
-
22
-
-
0037869060
-
Recombinant TCR ligand induces tolerance to myelin oligodendrocyte glycoprotein 35-55 peptide and reverses clinical and histological signs of chronic experimental autoimmune encephalomyelitis in HLA-DR2 transgenic mice
-
AA Vandenbark C Rich J Mooney A Zamora C Wang J Huan L Fugger H Offner R Jones GG Burrows 2003 Recombinant TCR ligand induces tolerance to myelin oligodendrocyte glycoprotein 35-55 peptide and reverses clinical and histological signs of chronic experimental autoimmune encephalomyelitis in HLA-DR2 transgenic mice J Immunol 171 127 133 12816990 1:CAS:528: DC%2BD3sXks12jtr4%3D (Pubitemid 36745280)
-
(2003)
Journal of Immunology
, vol.171
, Issue.1
, pp. 127-133
-
-
Vandenbark, A.A.1
Rich, C.2
Mooney, J.3
Zamora, A.4
Wang, C.5
Huan, J.6
Fugger, L.7
Offner, H.8
Jones, R.9
Burrows, G.G.10
-
23
-
-
36248944158
-
A promising therapeutic approach for multiple sclerosis: Recombinant T-cell receptor ligands modulate experimental autoimmune encephalomyelitis by reducing interleukin-17 production and inhibiting migration of encephalitogenic cells into the CNS
-
DOI 10.1523/JNEUROSCI.3599-07.2007
-
S Sinha S Subramanian TM Proctor LJ Kaler M Grafe R Dahan J Huan AA Vandenbark GG Burrows H Offner 2007 A promising therapeutic approach for multiple sclerosis: recombinant T-cell receptor ligands modulate experimental autoimmune encephalomyelitis by reducing interleukin-17 production and inhibiting migration of encephalitogenic cells into the CNS J Neurosci 27 12531 12539 10.1523/JNEUROSCI.3599-07.2007 18003831 10.1523/JNEUROSCI.3599-07.2007 1:CAS:528:DC%2BD2sXhsVSgs7fM (Pubitemid 350127826)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.46
, pp. 12531-12539
-
-
Sinha, S.1
Subramanian, S.2
Proctor, T.M.3
Kaler, L.J.4
Grafe, M.5
Dahan, R.6
Huan, J.7
Vandenbark, A.A.8
Burrows, G.G.9
Offner, H.10
-
24
-
-
77954562729
-
Recombinant TCR ligand reverses clinical signs and CNS damage of EAE induced by recombinant human MOG
-
10.1007/s11481-009-9175-1 19789980 10.1007/s11481-009-9175-1
-
S Sinha S Subramanian A Emerson-Webber M Lindner GG Burrows M Grafe C Linington AA Vandenbark CC Bernard H Offner 2010 Recombinant TCR ligand reverses clinical signs and CNS damage of EAE induced by recombinant human MOG J Neuroimmune Pharmacol 5 231 239 10.1007/s11481-009-9175-1 19789980 10.1007/s11481-009-9175-1
-
(2010)
J Neuroimmune Pharmacol
, vol.5
, pp. 231-239
-
-
Sinha, S.1
Subramanian, S.2
Emerson-Webber, A.3
Lindner, M.4
Burrows, G.G.5
Grafe, M.6
Linington, C.7
Vandenbark, A.A.8
Bernard, C.C.9
Offner, H.10
-
25
-
-
77955657048
-
Recombinant T cell receptor ligand (RTL) for the treatment of multiple sclerosis: Report of a phase i clinical trial
-
V Yadav D Bourdette JD Bowen SG Lynch D Mattson J Preiningerova C Rose RB Stead AJ Ferro AS Goldstein GG Burrows H Offner AA Vandenbark 2010 Recombinant T cell receptor ligand (RTL) for the treatment of multiple sclerosis: report of a phase I clinical trial Neurology 74 A293 A294
-
(2010)
Neurology
, vol.74
-
-
Yadav, V.1
Bourdette, D.2
Bowen, J.D.3
Lynch, S.G.4
Mattson, D.5
Preiningerova, J.6
Rose, C.7
Stead, R.B.8
Ferro, A.J.9
Goldstein, A.S.10
Burrows, G.G.11
Offner, H.12
Vandenbark, A.A.13
-
28
-
-
76049117037
-
A promising therapeutic approach for treatment of posterior uveitis: Recombinant T cell receptor ligand protects Lewis rats from acute and recurrent experimental autoimmune uveitis
-
10.1159/000281815 20145422 10.1159/000281815 1:CAS:528: DC%2BC3cXntFSisbg%3D
-
G Adamus LJ Karren J Mooney GG Burrows 2010 A promising therapeutic approach for treatment of posterior uveitis: recombinant T cell receptor ligand protects Lewis rats from acute and recurrent experimental autoimmune uveitis Ophthalmic Res 44 24 33 10.1159/000281815 20145422 10.1159/000281815 1:CAS:528:DC%2BC3cXntFSisbg%3D
-
(2010)
Ophthalmic Res
, vol.44
, pp. 24-33
-
-
Adamus, G.1
Karren, L.J.2
Mooney, J.3
Burrows, G.G.4
-
29
-
-
40449142272
-
MHC class II derived recombinant T cell receptor ligands protect DBA/1LacJ mice from collagen-induced arthritis
-
18178865 1:CAS:528:DC%2BD1cXhsVOqug%3D%3D
-
J Huan LJ Kaler JL Mooney S Subramanian C Hopke AA Vandenbark EF Rosloniec GG Burrows H Offner 2008 MHC class II derived recombinant T cell receptor ligands protect DBA/1LacJ mice from collagen-induced arthritis J Immunol 180 1249 1257 18178865 1:CAS:528:DC%2BD1cXhsVOqug%3D%3D
-
(2008)
J Immunol
, vol.180
, pp. 1249-1257
-
-
Huan, J.1
Kaler, L.J.2
Mooney, J.L.3
Subramanian, S.4
Hopke, C.5
Vandenbark, A.A.6
Rosloniec, E.F.7
Burrows, G.G.8
Offner, H.9
-
30
-
-
78650846041
-
Single-chain recombinant HLA-DQ2.5/peptide molecules block alpha2-gliadin-specific pathogenic CD4(+) T-cell proliferation and attenuate production of inflammatory cytokines: A potential therapy for celiac disease
-
10.1038/mi.2010.44 20736999
-
J Huan R Meza-Romero JL Mooney AA Vandenbark H Offner GG Burrows 2010 Single-chain recombinant HLA-DQ2.5/peptide molecules block alpha2-gliadin- specific pathogenic CD4(+) T-cell proliferation and attenuate production of inflammatory cytokines: a potential therapy for celiac disease Mucosal Immunol 10.1038/mi.2010.44 20736999
-
(2010)
Mucosal Immunol
-
-
Huan, J.1
Meza-Romero, R.2
Mooney, J.L.3
Vandenbark, A.A.4
Offner, H.5
Burrows, G.G.6
-
31
-
-
33748490906
-
+ T cells
-
AP Fontenot TS Keizer M McCleskey DG Mack R Meza-Romero J Huan DM Edwards YK Chou AA Vandenbark B Scott GG Burrows 2006 Recombinant HLA-DP2 binds beryllium and tolerizes beryllium-specific pathogenic CD4+ T cells J Immunol 177 3874 3883 16951350 1:CAS:528:DC%2BD28XptlOgsLo%3D (Pubitemid 44359922)
-
(2006)
Journal of Immunology
, vol.177
, Issue.6
, pp. 3874-3883
-
-
Fontenot, A.P.1
Keizer, T.S.2
McCleskey, M.3
Mack, D.G.4
Meza-Romero, R.5
Huan, J.6
Edwards, D.M.7
Chou, Y.K.8
Vandenbark, A.A.9
Scott, B.10
Burrows, G.G.11
-
32
-
-
67650070642
-
Recombinant T cell receptor ligand treats experimental stroke
-
10.1161/STROKEAHA.108.543991 19443805 10.1161/STROKEAHA.108.543991 1:CAS:528:DC%2BD1MXnsFyjuro%3D
-
S Subramanian B Zhang Y Kosaka GG Burrows MR Grafe AA Vandenbark PD Hurn H Offner 2009 Recombinant T cell receptor ligand treats experimental stroke Stroke 40 2539 2545 10.1161/STROKEAHA.108.543991 19443805 10.1161/STROKEAHA.108. 543991 1:CAS:528:DC%2BD1MXnsFyjuro%3D
-
(2009)
Stroke
, vol.40
, pp. 2539-2545
-
-
Subramanian, S.1
Zhang, B.2
Kosaka, Y.3
Burrows, G.G.4
Grafe, M.R.5
Vandenbark, A.A.6
Hurn, P.D.7
Offner, H.8
-
33
-
-
0024513169
-
The role of major histocompatibility molecules in antigen-specific immune responses
-
J McCluskey R Blok L Kjer-Nielsen 1989 The role of major histocompatibility molecules in antigen-specific immune responses Transplant Proc 21 591 594 2495622 1:CAS:528:DyaL1MXkt1WksLY%3D (Pubitemid 19118134)
-
(1989)
Transplantation Proceedings
, vol.21
, Issue.1
, pp. 591-594
-
-
McCluskey, J.1
Blok, R.2
Kjer-Nielsen, L.3
-
34
-
-
0029100015
-
Dimerization of soluble major histocompatibility complex-peptide complexes is sufficient for activation of T cell hybridoma and induction of unresponsiveness
-
7629504 10.1084/jem.182.2.439 1:CAS:528:DyaK2MXntFKhs7Y%3D
-
JP Abastado YC Lone A Casrouge G Boulot P Kourilsky 1995 Dimerization of soluble major histocompatibility complex-peptide complexes is sufficient for activation of T cell hybridoma and induction of unresponsiveness J Exp Med 182 439 447 7629504 10.1084/jem.182.2.439 1:CAS:528:DyaK2MXntFKhs7Y%3D
-
(1995)
J Exp Med
, vol.182
, pp. 439-447
-
-
Abastado, J.P.1
Lone, Y.C.2
Casrouge, A.3
Boulot, G.4
Kourilsky, P.5
-
35
-
-
0022637719
-
The requirements for antigen multivalency in class I antigen recognition and triggering of primed precursor cytolytic T lymphocytes
-
SH Herrmann MF Mescher 1986 The requirements for antigen multivalency in class I antigen recognition and triggering of primed precursor cytolytic T lymphocytes J Immunol 136 2816 2825 3082973 1:CAS:528:DyaL28XitVGisro%3D (Pubitemid 16107182)
-
(1986)
Journal of Immunology
, vol.136
, Issue.8
, pp. 2816-2825
-
-
Herrmann, S.H.1
Mescher, M.F.2
-
36
-
-
0035451465
-
Antigen-specific blockade of T cells in vivo using dimeric MHC peptide
-
SM O'Herrin JE Slansky Q Tang MA Markiewicz TF Gajewski DM Pardoll JP Schneck JA Bluestone 2001 Antigen-specific blockade of T cells in vivo using dimeric MHC peptide J Immunol 167 2555 2560 11509595 (Pubitemid 32768882)
-
(2001)
Journal of Immunology
, vol.167
, Issue.5
, pp. 2555-2560
-
-
O'Herrin, S.M.1
Slansky, J.E.2
Tang, Q.3
Markiewicz, M.A.4
Gajewski, T.F.5
Pardoll, D.M.6
Schneck, J.P.7
Bluestone, J.A.8
-
37
-
-
77951882989
-
Reversal of autoimmunity by boosting memory-like autoregulatory T cells
-
10.1016/j.immuni.2010.03.015 20381385 10.1016/j.immuni.2010.03.015 1:CAS:528:DC%2BC3cXlslSisrw%3D
-
S Tsai A Shameli J Yamanouchi X Clemente-Casares J Wang P Serra Y Yang Z Medarova A Moore P Santamaria 2010 Reversal of autoimmunity by boosting memory-like autoregulatory T cells Immunity 32 568 580 10.1016/j.immuni.2010.03. 015 20381385 10.1016/j.immuni.2010.03.015 1:CAS:528:DC%2BC3cXlslSisrw%3D
-
(2010)
Immunity
, vol.32
, pp. 568-580
-
-
Tsai, S.1
Shameli, A.2
Yamanouchi, J.3
Clemente-Casares, X.4
Wang, J.5
Serra, P.6
Yang, Y.7
Medarova, Z.8
Moore, A.9
Santamaria, P.10
-
38
-
-
0036499141
-
A single-chain class II MHC-IgG3 fusion protein inhibits autoimmune arthritis by induction of antigen-specific hyporesponsiveness
-
L Zuo CM Cullen ML DeLay S Thornton LK Myers EF Rosloniec GP Boivin R Hirsch 2002 A single-chain class II MHC-IgG3 fusion protein inhibits autoimmune arthritis by induction of antigen-specific hyporesponsiveness J Immunol 168 2554 2559 11859151 1:CAS:528:DC%2BD38XhvVegtr0%3D (Pubitemid 34171864)
-
(2002)
Journal of Immunology
, vol.168
, Issue.5
, pp. 2554-2559
-
-
Zuo, L.1
Cullen, C.M.2
DeLay, M.L.3
Thornton, S.4
Myers, L.K.5
Rosloniec, E.F.6
Boivin, G.P.7
Hirsch, R.8
-
40
-
-
0036226602
-
+ T cells by a soluble dimeric peptide-MHC class II chimera
-
DOI 10.1038/ni770
-
S Casares A Hurtado RC McEvoy A Sarukhan H von Boehmer TD Brumeanu 2002 Down-regulation of diabetogenic CD4+ T cells by a soluble dimeric peptide-MHC class II chimera Nat Immunol 3 383 391 10.1038/ni770ni770 11862219 10.1038/ni770 1:CAS:528:DC%2BD38Xis1Kktr4%3D (Pubitemid 34308627)
-
(2002)
Nature Immunology
, vol.3
, Issue.4
, pp. 383-391
-
-
Casares, S.1
Hurtado, A.2
McEvoy, R.C.3
Sarukhan, A.4
Von Boehmer, H.5
Brumeanu, T.-D.6
-
41
-
-
49149123257
-
A peptide-major histocompatibility complex II chimera favors survival of pancreatic beta-islets grafted in type 1 diabetic mice
-
10.1097/TP.0b013e31817752cc00007890-200806270-00007 18580462 10.1097/TP.0b013e31817752cc 1:CAS:528:DC%2BD1cXns1Ogt7k%3D
-
S Casares M Lin N Zhang JR Teijaro C Stoica R McEvoy DL Farber C Bona TD Brumeanu 2008 A peptide-major histocompatibility complex II chimera favors survival of pancreatic beta-islets grafted in type 1 diabetic mice Transplantation 85 1717 1725 10.1097/TP.0b013e31817752cc00007890-200806270-00007 18580462 10.1097/TP.0b013e31817752cc 1:CAS:528:DC%2BD1cXns1Ogt7k%3D
-
(2008)
Transplantation
, vol.85
, pp. 1717-1725
-
-
Casares, S.1
Lin, M.2
Zhang, N.3
Teijaro, J.R.4
Stoica, C.5
McEvoy, R.6
Farber, D.L.7
Bona, C.8
Brumeanu, T.D.9
-
42
-
-
26044438468
-
Soluble, dimeric HLA DR4-peptide chimeras: An approach for detection and immunoregulation of human type-1 diabetes
-
DOI 10.1002/eji.200526158
-
I Preda RC McEvoy M Lin CA Bona R Rapaport TD Brumeanu S Casares 2005 Soluble, dimeric HLA DR4-peptide chimeras: an approach for detection and immunoregulation of human type-1 diabetes Eur J Immunol 35 2762 2775 10.1002/eji.200526158 16106371 10.1002/eji.200526158 1:CAS:528: DC%2BD2MXhtVOqsL3E (Pubitemid 41404059)
-
(2005)
European Journal of Immunology
, vol.35
, Issue.9
, pp. 2762-2775
-
-
Preda, I.1
McEvoy, R.C.2
Lin, M.3
Bona, C.A.4
Rapaport, R.5
Brumeanu, T.D.6
Casares, S.7
-
43
-
-
77956112950
-
Reversal of type 1 diabetes by a new MHC II-peptide chimera: "Single-epitope-mediated suppression" to stabilize a polyclonal autoimmune T-cell process
-
10.1002/eji.200940094 20540111 10.1002/eji.200940094 1:CAS:528: DC%2BC3cXpsF2rsLg%3D
-
M Lin C Stoica-Nazarov J Surls M Kehl C Bona C Olsen TD Brumeanu S Casares 2010 Reversal of type 1 diabetes by a new MHC II-peptide chimera: "Single-epitope-mediated suppression" to stabilize a polyclonal autoimmune T-cell process Eur J Immunol 40 2277 2288 10.1002/eji.200940094 20540111 10.1002/eji.200940094 1:CAS:528:DC%2BC3cXpsF2rsLg%3D
-
(2010)
Eur J Immunol
, vol.40
, pp. 2277-2288
-
-
Lin, M.1
Stoica-Nazarov, C.2
Surls, J.3
Kehl, M.4
Bona, C.5
Olsen, C.6
Brumeanu, T.D.7
Casares, S.8
-
44
-
-
0242494202
-
Peptide-MHC Class II Dimers as Therapeutics to Modulate Antigen-Specific T Cell Responses in Autoimmune Diabetes
-
EL Masteller MR Warner W Ferlin V Judkowski D Wilson N Glaichenhaus JA Bluestone 2003 Peptide-MHC class II dimers as therapeutics to modulate antigen-specific T cell responses in autoimmune diabetes J Immunol 171 5587 5595 14607967 1:CAS:528:DC%2BD3sXoslyhs7c%3D (Pubitemid 37432850)
-
(2003)
Journal of Immunology
, vol.171
, Issue.10
, pp. 5587-5595
-
-
Masteller, E.L.1
Warner, M.R.2
Ferlin, W.3
Judkowski, V.4
Wilson, D.5
Glaichenhaus, N.6
Bluestone, J.A.7
-
45
-
-
70449711382
-
Suppression of ongoing T cell-mediated autoimmunity by peptide-MHC class II dimer vaccination
-
19752238 10.4049/jimmunol.0901616 1:CAS:528:DC%2BD1MXhtFGjsLrM
-
L Li Z Yi B Wang R Tisch 2009 Suppression of ongoing T cell-mediated autoimmunity by peptide-MHC class II dimer vaccination J Immunol 183 4809 4816 19752238 10.4049/jimmunol.0901616 1:CAS:528:DC%2BD1MXhtFGjsLrM
-
(2009)
J Immunol
, vol.183
, pp. 4809-4816
-
-
Li, L.1
Yi, Z.2
Wang, B.3
Tisch, R.4
-
46
-
-
0242364727
-
A comprehensive guide to antibody and T-cell responses in type 1 diabetes
-
DOI 10.1034/j.1399-0039.2003.00152.x
-
S Lieberman T DiLorenzo 2003 A comprehensive guide to antibody and T-cell responses in type 1 diabetes Tissue Antigens 62 359 377 14617043 10.1034/j.1399-0039.2003.00152.x 1:CAS:528:DC%2BD3sXpsVOiurw%3D (Pubitemid 37338877)
-
(2003)
Tissue Antigens
, vol.62
, Issue.5
, pp. 359-377
-
-
Lieberman, S.M.1
DiLorenzo, T.P.2
-
47
-
-
57849152536
-
CD8+ T-cells in autoimmune diabetes
-
19111164 10.1016/S0065-2776(08)00804-3 1:CAS:528:DC%2BD1MXpsFeis78%3D
-
S Tsai A Shameli P Santamaria 2008 CD8+ T-cells in autoimmune diabetes Adv Immunol 100 79 124 19111164 10.1016/S0065-2776(08)00804-3 1:CAS:528:DC%2BD1MXpsFeis78%3D
-
(2008)
Adv Immunol
, vol.100
, pp. 79-124
-
-
Tsai, S.1
Shameli, A.2
Santamaria, P.3
-
48
-
-
18744366947
-
Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice
-
DOI 10.1038/nature03523
-
M Nakayama N Abiru H Moriyama N Babaya E Liu D Miao L Yu DR Wegmann JC Hutton JF Elliott GS Eisenbarth 2005 Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice Nature 435 220 223 15889095 10.1038/nature03523 1:CAS:528:DC%2BD2MXktVWhtLg%3D (Pubitemid 40685949)
-
(2005)
Nature
, vol.435
, Issue.7039
, pp. 220-223
-
-
Nakayama, M.1
Abiru, N.2
Moriyama, H.3
Babaya, N.4
Liu, E.5
Miao, D.6
Yu, L.7
Wegmann, D.R.8
Hutton, J.C.9
Elliott, J.F.10
Eisenbarth, G.S.11
-
49
-
-
70349194383
-
Thymus-specific deletion of insulin induces autoimmune diabetes
-
19680229 10.1038/emboj.2009.212 1:CAS:528:DC%2BD1MXpsFKgtLo%3D
-
Y Fan WA Rudert M Grupillo J He G Sisino M Trucco 2009 Thymus-specific deletion of insulin induces autoimmune diabetes EMBO J 28 2812 2824 19680229 10.1038/emboj.2009.212 1:CAS:528:DC%2BD1MXpsFKgtLo%3D
-
(2009)
EMBO J
, vol.28
, pp. 2812-2824
-
-
Fan, Y.1
Rudert, W.A.2
Grupillo, M.3
He, J.4
Sisino, G.5
Trucco, M.6
-
50
-
-
77951884435
-
The long and winding road to understanding and conquering type 1 diabetes
-
20412754 10.1016/j.immuni.2010.04.003 1:CAS:528:DC%2BC3cXlslSjurY%3D
-
P Santamaria 2010 The long and winding road to understanding and conquering type 1 diabetes Immunity 32 437 445 20412754 10.1016/j.immuni.2010. 04.003 1:CAS:528:DC%2BC3cXlslSjurY%3D
-
(2010)
Immunity
, vol.32
, pp. 437-445
-
-
Santamaria, P.1
-
51
-
-
20944441042
-
Prevention of diabetes by manipulation of anti-IGRP autoimmunity: High efficiency of a low-affinity peptide
-
DOI 10.1038/nm1250
-
B Han P Serra A Amrani J Yamanouchi AF Maree L Edelstein-Keshet P Santamaria 2005 Prevention of diabetes by manipulation of anti-IGRP autoimmunity: high efficiency of a low-affinity peptide Nat Med 11 645 652 10.1038/nm1250 15908957 10.1038/nm1250 1:CAS:528:DC%2BD2MXkslOksLw%3D (Pubitemid 40868305)
-
(2005)
Nature Medicine
, vol.11
, Issue.6
, pp. 645-652
-
-
Han, B.1
Serra, P.2
Amrani, A.3
Yamanouchi, J.4
Maree, A.F.M.5
Edelstein-Keshet, L.6
Santamaria, P.7
-
52
-
-
77952686356
-
In situ recognition of autoantigen as an essential gatekeeper in autoimmune inflammation
-
20439719 10.1073/pnas.0913835107 1:CAS:528:DC%2BC3cXmslGrtbo%3D
-
J Wang S Tsai A Shameli J Yamanouchi G Alkemade P Santamaria 2010 In situ recognition of autoantigen as an essential gatekeeper in autoimmune inflammation Proc Natl Acad Sci USA 107 20 9317 9322 20439719 10.1073/pnas.0913835107 1:CAS:528:DC%2BC3cXmslGrtbo%3D
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.20
, pp. 9317-9322
-
-
Wang, J.1
Tsai, S.2
Shameli, A.3
Yamanouchi, J.4
Alkemade, G.5
Santamaria, P.6
-
53
-
-
9144271119
-
+ T cell reactivity to three islet antigens, including the newly identified widely expressed dystrophia myotonica kinase
-
S Lieberman T Takaki B Han P Santamaria D Serreze T DiLorenzo 2004 Individual nonobese diabetic mice exhibit unique patterns of CD8+ T cell reactivity to three islet antigens, including the newly identified widely expressed dystrophia myotonica kinase J Immunol 173 6727 6734 15557165 1:CAS:528:DC%2BD2cXhtVShsb%2FM (Pubitemid 39541058)
-
(2004)
Journal of Immunology
, vol.173
, Issue.11
, pp. 6727-6734
-
-
Lieberman, S.M.1
Takaki, T.2
Han, B.3
Santamaria, P.4
Serreze, D.V.5
DiLorenzo, T.P.6
-
54
-
-
0034680105
-
Progression of autoimmune diabetes driven by avidity maturation of a T-cell population
-
10.1038/35021081 10963600 10.1038/35021081 1:CAS:528:DC%2BD3cXmt1Cgur4%3D
-
A Amrani J Verdaguer P Serra S Tafuro R Tan P Santamaria 2000 Progression of autoimmune diabetes driven by avidity maturation of a T-cell population Nature 406 739 742 10.1038/35021081 10963600 10.1038/35021081 1:CAS:528:DC%2BD3cXmt1Cgur4%3D
-
(2000)
Nature
, vol.406
, pp. 739-742
-
-
Amrani, A.1
Verdaguer, J.2
Serra, P.3
Tafuro, S.4
Tan, R.5
Santamaria, P.6
-
55
-
-
0028031644
-
Peptide-induced T-cell tolerance to prevent autoimmune diabetes in a transgenic mouse model
-
P Aichele D Kyburz P Ohashi B Odermatt R Zinkernagel H Hengartner H Pircher 1994 Peptide-induced T-cell tolerance to prevent autoimmune diabetes in a transgenic mouse model Proc Natl Acad Sci USA 91 444 448 8290546 10.1073/pnas.91.2.444 1:CAS:528:DyaK2cXhs1WntLo%3D (Pubitemid 24041418)
-
(1994)
Proceedings of the National Academy of Sciences of the United States of America
, vol.91
, Issue.2
, pp. 444-448
-
-
Aichele, P.1
Kyburz, D.2
Ohashi, P.S.3
Odermatt, B.4
Zinkernagel, R.M.5
Hengartner, H.6
Pircher, H.7
-
57
-
-
0346366975
-
Cross-Priming of Diabetogenic T Cells Dissociated from CTL-Induced Shedding of β Cell Autoantigens
-
J Yamanouchi J Verdaguer B Han A Amrani P Serra P Santamaria 2003 Cross-priming of diabetogenic T cells dissociated from CTL-induced shedding of beta cell autoantigens J Immunol 171 6900 6909 14662897 1:CAS:528: DC%2BD3sXpsV2ruro%3D (Pubitemid 37532126)
-
(2003)
Journal of Immunology
, vol.171
, Issue.12
, pp. 6900-6909
-
-
Yamanouchi, J.1
Verdaguer, J.2
Han, B.3
Amrani, A.4
Serra, P.5
Santamaria, P.6
-
58
-
-
66049120527
-
How the immune system achieves self-nonself discrimination during adaptive immunity
-
19477320 10.1016/S0065-2776(09)01202-4 1:CAS:528:DC%2BD1MXhtVSnsbjP
-
H Jiang L Chess 2009 How the immune system achieves self-nonself discrimination during adaptive immunity Adv Immunol 102 95 133 19477320 10.1016/S0065-2776(09)01202-4 1:CAS:528:DC%2BD1MXhtVSnsbjP
-
(2009)
Adv Immunol
, vol.102
, pp. 95-133
-
-
Jiang, H.1
Chess, L.2
|