High Throughput Screening

Encyclopedia of Toxicology: Third Edition

Volumn , Issue , 2014, Pages 916-917

  Attene Ramos, M S ^a   Austin, C P ^a   Xia, M ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Alternative methods for toxicity testing; High throughput screening; In vitro assays; Mechanistic toxicology; Mode of action, Quantitative high throughput screening; Tox21 initiative

Indexed keywords

EID: 84929097562     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-12-386454-3.00209-8     Document Type: Chapter

References (7)

1. Inglese J., Auld D.S., Jadhav A., et al. Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries. Proc. Natl. Acad. Sci. USA 2006, 103:11473-11478.
2. Inglese J., Johnson R.L., Simeonov A., et al. High throughput screening assays for the investigation of chemical biology. Nat. Chem. Biol. 2007, 3:466-479.
3. Mayr L.M., Fuerst P. The future of high-throughput screening. J. Biomol. Screen. 2008, 13:443-448.
4. Shukla S.J., Huang R., Austin C.P., Xia M. The future of toxicity testing: a focus on in vitro methods using a quantitative high throughput screening platform. Drug Discov. Today 2010, 15:997-1007.
5. Thomas C.J., Auld D.S., Huang R., et al. The pilot phase of the NIH Chemical Genomics Center. Curr. Top. Med. Chem. 2009, 9:1181-1193.
6. http://nctt.nih.gov/.
7. http://assay.nih.gov/assay/index.php/Table_of_Contents.