Skeletal, neuromuscular and fitness impairments among children with newly diagnosed acute lymphoblastic leukemia

Leukemia and Lymphoma

Volumn 56, Issue 4, 2015, Pages 1004-1011

  Ness, Kirsten K ^a   Kaste, Sue C ^a   Zhu, Liang ^a   Pui, Ching Hon ^a   Jeha, Sima ^a   Nathan, Paul C ^b   Inaba, Hiroto ^a   Wasilewski Masker, Karen ^c   Shah, Durga ^c   Wells, Robert J ^d   Karlage, Robyn E ^a   Robison, Leslie L ^a   Cox, Cheryl L ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Acute lymphoblastic leukemia; Muscle strength; Pediatric; Physical endurance; Quality of life

Indexed keywords

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ADULT; ARTICLE; BODY COMPOSITION; BODY MASS; BONE DENSITY; CANCER DIAGNOSIS; CHILD; CONTROLLED STUDY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MUSCLE STRENGTH; MUSCLE WEAKNESS; MUSCULOSKELETAL DISEASE; NEUROMUSCULAR DISEASE; PHYSICAL DISEASE; PRIORITY JOURNAL; QUADRICEPS FEMORIS MUSCLE; QUALITY OF LIFE; KINESIOTHERAPY; MOTOR PERFORMANCE; MULTIVARIATE ANALYSIS; NEUROMUSCULAR JUNCTION; PATHOPHYSIOLOGY; PHYSIOLOGY; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PRESCHOOL CHILD; PROCEDURES; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE; STATISTICAL MODEL; WALKING;

ADOLESCENT; BODY MASS INDEX; BONE DENSITY; CHILD; CHILD, PRESCHOOL; EXERCISE THERAPY; FEMALE; HUMANS; LOGISTIC MODELS; MALE; MOTOR SKILLS; MULTIVARIATE ANALYSIS; MUSCLE STRENGTH; NEUROMUSCULAR JUNCTION; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; QUALITY OF LIFE; SINGLE-BLIND METHOD; WALKING;

EID: 84929092348     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.3109/10428194.2014.944519     Document Type: Article

References (61)

1. Kaste SC, Rai SN, Fleming K, et al. Changes in bone mineral density in survivors of childhood acute lymphoblastic leukemia. Pediatr Blood Cancer 2006;46:77-87.
2. Le Meignen M, Auquier P, Barlogis V, et al. Bone mineral density in adult survivors of childhood acute leukemia: impact of hematopoietic stem cell transplantation and other treatment modalities. Blood 2011;118:1481-1489.
3. Makitie O, Heikkinen R, Toiviainen-Salo S, et al. Long-term skeletal consequences of childhood acute lymphoblastic leukemia in adult males: a cohort study. Eur J Endocrinol 2013;168:281-288.
4. Mandel K, Atkinson S, Barr RD, et al. Skeletal morbidity in childhood acute lymphoblastic leukemia. J Clin Oncol 2004;22: 1215-1221.
5. Maniadaki I, Stiakaki E, Germanakis I, et al. Evaluation of bone mineral density at different phases of therapy of childhood all. Pediatr Hematol Oncol 2006;23:11-18.
6. Janiszewski PM, Oeffinger KC, Church TS, et al. Abdominal obesity, liver fat, and muscle composition in survivors of childhood acute lymphoblastic leukemia. J Clin Endocrinol Metab 2007;92:3816-3821.
7. Ness KK, Baker KS, Dengel DR, et al. Body composition, muscle strength deficits and mobility limitations in adult survivors of childhood acute lymphoblastic leukemia. Pediatr Blood Cancer 2007;49: 975-981.
8. Harila-Saari AH, Huuskonen UE, Tolonen U, et al. Motor nervous pathway function is impaired after treatment of childhood acute lymphoblastic leukemia: a study with motor evoked potentials. Med Pediatr Oncol 2001;36:345-351.
9. Lehtinen SS, Huuskonen UE, Harila-Saari AH, et al. Motor nervous system impairment persists in long-term survivors of childhood acute lymphoblastic leukemia. Cancer 2002;94:2466-2473.
10. Ramchandren S, Leonard M, Mody RJ, et al. Peripheral neuropathy in survivors of childhood acute lymphoblastic leukemia. J Peripher Nerv Syst 2009;14:184-189.
11. Bar G, Black PC, Gutjahr P, et al. Recovery kinetics of heart rate and oxygen uptake in long-term survivors of acute leukemia in childhood. Eur J Pediatr 2007;166:1135-1142.
12. Jarvela LS, Niinikoski H, Lahteenmaki PM, et al. Physical activity and fitness in adolescent and young adult long-term survivors of childhood acute lymphoblastic leukaemia. J Cancer Surviv 2010; 4:339-345.
13. Tonorezos ES, Snell PG, Moskowitz CS, et al. Reduced cardiorespiratory fitness in adult survivors of childhood acute lymphoblastic leukemia. Pediatr Blood Cancer 2013;60:1358-1364.
14. van Brussel M, Takken T, van der Net J, et al. Physical function and fitness in long-term survivors of childhood leukaemia. Pediatr Rehabil 2006;9:267-274.
15. Warner JT, Bell W, Webb DK, et al. Daily energy expenditure and physical activity in survivors of childhood malignancy. Pediatr Res 1998;43:607-613.
16. Jarfelt M, Fors H, Lannering B, et al. Bone mineral density and bone turnover in young adult survivors of childhood acute lymphoblastic leukaemia. Eur J Endocrinol 2006;154:303-309.
17. Joyce ED, Nolan VG, Ness KK, et al. Association of muscle strength and bone mineral density in adult survivors of childhood acute lymphoblastic leukemia. Arch Phys Med Rehabil 2011;92: 873-879.
18. Tillmann V, Darlington AS, Eiser C, et al. Male sex and low physical activity are associated with reduced spine bone mineral density in survivors of childhood acute lymphoblastic leukemia. J Bone Miner Res 2002;17:1073-1080.
19. Alos N, Grant RM, Ramsay T, et al. High incidence of vertebral fractures in children with acute lymphoblastic leukemia 12 months after the initiation of therapy. J Clin Oncol 2012;30:2760-2767.
20. Diessel E, Fuerst T, Njeh CF, et al. Evaluation of a new body composition phantom for quality control and cross calibration of DXA devices. J Appl Physiol 2000;89:599-605.
21. Kalender WA. A phantom for standardization and quality control in spinal bone mineral measurements by QCT and DXA: design considerations and specifications. Med Phys 1992;19:583-586.
22. Kalender WA, Felsenberg D, Genant HK, et al. The European Spine Phantom - a tool for standardization and quality control in spinal bone mineral measurements by DXA and QCT. Eur J Radiol 1995;20:83-92.
23. Molgaard C, Thomsen BL, Prentice A, et al. Whole body bone mineral content in healthy children and adolescents. Arch Dis Child 1997;76:9-15.
24. Orwoll ES, Oviatt SK, Biddle JA. Precision of dual-energy x-ray absorptiometry: development of quality control rules and their application in longitudinal studies. J Bone Miner Res 1993;8: 693-699.
25. Zemel BS, Leonard MB, Kelly A, et al. Height adjustment in assessing dual energy x-ray absorptiometry measurements of bone mass and density in children. J Clin Endocrinol Metab 2010;95: 1265-1273.
26. Centers for Disease Control and Prevention. A SAS program for the CDC growth charts. Atlanta, GA: CDC; 26 March 2014. Available from: http://www.cdc.gov/nccdphp/dnpao/growthcharts/resources/sas.htm
27. Marchese VG, Chiarello LA, Lange BJ. Effects of physical therapy intervention for children with acute lymphoblastic leukemia. Pediatr Blood Cancer 2004;42:127-133.
28. Soucie JM, Wang C, Forsyth A, et al. Range of motion measurements: reference values and a database for comparison studies. Haemophilia 2011;17:500-507.
29. Eek MN, Kroksmark AK, Beckung E. Isometric muscle torque in children 5 to 15 years of age: normative data. Arch Phys Med Rehabil 2006;87:1091-1099.
30. Merlini L, Mazzone ES, Solari A, et al. Reliability of hand-held dynamometry in spinal muscular atrophy. Muscle Nerve 2002;26: 64-70.
31. Hager-Ross C, Rosblad B. Norms for grip strength in children aged 4-16 years. Acta Paediatr 2002;91:617-625.
32. Mathiowetz V, Wiemer DM, Federman SM. Grip and pinch strength: norms for 6- to 19-year olds. Am J Occup Ther 1986;40: 705-711.
33. Bruininks RH, Bruininks BD. BOT2 Bruininks-Oseretsky Test of Motor Proficiency. Circle Pines, MN: AGS Publishing; 2005.
34. Geiger R, Strasak A, Treml B, et al. Six-minute walk test in children and adolescents. J Pediatr 2007;150:395-399.
35. Russell KM, Hudson M, Long A, et al. Assessment of healthrelated quality of life in children with cancer: consistency and agreement between parent and child reports. Cancer 2006;106: 2267-2274.
36. Landgraf JM, Abetz L, Ware JE. Child Health Questionnaire (CHQ): a user's manual. Boston, MA: HealthAct; 1999.
37. Halton JM, Atkinson SA, Fraher L, et al. Altered mineral metabolism and bone mass in children during treatment for acute lymphoblastic leukemia. J Bone Miner Res 1996;11:1774-1783.
38. Rayar MS, Nayiager T, Webber CE, et al. Predictors of bony morbidity in children with acute lymphoblastic leukemia. Pediatr Blood Cancer 2012;59:77-82.
39. Riccio I, Marcarelli M, Del Regno N, et al. Musculoskeletal problems in pediatric acute leukemia. J Pediatr Orthop B 2013;22: 264-269.
40. van der Sluis IM, van den Heuvel-Eibrink MM, Hahlen K, et al. Altered bone mineral density and body composition, and increased fracture risk in childhood acute lymphoblastic leukemia. J Pediatr 2002;141:204-210.
41. Swiatkiewicz V, Wysocki M, Odrowaz-Sypniewska G, et al. Bone mass and bone mineral metabolism at diagnosis and after intensive treatment in children with acute lymphoblastic leukemia. Med Pediatr Oncol 2003;41:578-580.
42. Halton J, Gaboury I, Grant R, et al. Advanced vertebral fracture among newly diagnosed children with acute lymphoblastic leukemia: Results of the Canadian Steroid-Associated Osteoporosis in the Pediatric Population (STOPP) research program. J Bone Miner Res 2009;24:1326-1334.
43. Atkinson SA, Halton JM, Bradley C, et al. Bone and mineral abnormalities in childhood acute lymphoblastic leukemia: influence of disease, drugs and nutrition. Int J Cancer Suppl 1998; 11:35-39.
44. Aldhafiri FK, McColl JH, Reilly JJ. Prevalence of being underweight and overweight and obesity at diagnosis in UK patients with childhood acute lymphoblastic leukaemia 1985-2002. J Hum Nutr Diet 2014;27:76-79.
45. Esbenshade AJ, Simmons JH, Koyama T, et al. Body mass index and blood pressure changes over the course of treatment of pediatric acute lymphoblastic leukemia. Pediatr Blood Cancer 2011;56: 372-378.
46. Ruiz JC, Mandel C, Garabedian M. Influence of spontaneous calcium intake and physical exercise on the vertebral and femoral bone mineral density of children and adolescents. J Bone Miner Res 1995;10:675-682.
47. Au LE, Rogers GT, Harris SS, et al. Associations of vitamin D intake with 25-hydroxyvitamin D in overweight and racially/ethnically diverse US children. J Acad Nutr Diet 2013;113:1511-1516.
48. Ness KK, Hudson MM, Pui CH, et al. Neuromuscular impairments in adult survivors of childhood acute lymphoblastic leukemia: associations with physical performance and chemotherapy doses. Cancer 2012;118:828-838.
49. Tan SY, Poh BK, Nadrah MH, et al. Nutritional status and dietary intake of children with acute leukaemia during induction or consolidation chemotherapy. J Hum Nutr Diet 2013.
50. Chow EJ, Pihoker C, Hunt K, et al. Obesity and hypertension among children after treatment for acute lymphoblastic leukemia. Cancer 2007;110:2313-2320.
51. Chow EJ, Pihoker C, Friedman DL, et al. Glucocorticoids and insulin resistance in children with acute lymphoblastic leukemia. Pediatr Blood Cancer 2013;60:621-626.
52. Orgel E, Sposto R, Malvar J, et al. Impact on survival and toxicity by duration of weight extremes during treatment for pediatric acute lymphoblastic leukemia: A report from the Children's Oncology Group. J Clin Oncol 2014;32:1331-1337.
53. Gurney JG, Ness KK, Sibley SD, et al. Metabolic syndrome and growth hormone deficiency in adult survivors of childhood acute lymphoblastic leukemia. Cancer 2006;107:1303-1312.
54. Oeffinger KC, Adams-Huet B, Victor RG, et al. Insulin resistance and risk factors for cardiovascular disease in young adult survivors of childhood acute lymphoblastic leukemia. J Clin Oncol 2009;27: 3698-3704.
55. Steinberger J, Sinaiko AR, Kelly AS, et al. Cardiovascular risk and insulin resistance in childhood cancer survivors. J Pediatr 2012;160:494-499.
56. Tonorezos ES, Vega GL, Sklar CA, et al. Adipokines, body fatness, and insulin resistance among survivors of childhood leukemia. Pediatr Blood Cancer 2012;58:31-36.
57. Rayar M, Webber CE, Nayiager T, et al. Sarcopenia in children with acute lymphoblastic leukemia. J Pediatr Hematol Oncol 2013; 35:98-102.
58. Kameda G, Vieker S, Duck C, et al. Paraneoplastic myopathy as a very rare manifestation of acute lymphoblastic leukemia. Klin Padiatr 2010;222:386-387.
59. Gocha Marchese V, Chiarello LA, Lange BJ. Strength and functional mobility in children with acute lymphoblastic leukemia. Med Pediatr Oncol 2003;40:230-232.
60. Bindels LB, Beck R, Schakman O, et al. Restoring specific lactobacilli levels decreases inflammation and muscle atrophy markers in an acute leukemia mouse model. PLoS One 2012;7:e37971.
61. Menconi M, Fareed M, O'Neal P, et al. Role of glucocorticoids in the molecular regulation of muscle wasting. Crit Care Med 2007;35:S602-608.