Systemic exposure to and disposition of catechols derived from salvia miltiorrhiza roots (Danshen) after intravenous dosing danhong injection in human subjects, rats, and dogs

Drug Metabolism and Disposition

Volumn 43, Issue 5, 2015, Pages 679-690

  Li, Meijuan ^a,b   Wang, Fengqing ^a   Huang, Yühong ^c   Du, Feifei ^a   Zhong, Chenchun ^a   Olaleye, Olajide E ^a   Jia, Weiwei ^a   Li, Yanfen ^c   Xu, Fang ^a   Dong, Jiajia ^a   Li, Jian ^a   Lim, Justin B R ^a   Zhao, Buchang ^d   Jia, Lifu ^d   Li, Li ^a,b   Li, Chuan ^a,b,e  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c TIANJIN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^d Buchang Pharmacy Group   (China)

^e INSTITUTE OF CHINESE MATERIA MEDICA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CATECHOL DERIVATIVE; CHINESE DRUG; DANHONG; LITHOSPERMIC ACID; PROTOCATECHUALDEHYDE; ROSMARINIC ACID; SALVIA MILTIORRHIZA EXTRACT; SALVIAFLASIDE; SALVIANOLIC ACID A; SALVIANOLIC ACID B; SALVIANOLIC ACID C; SALVIANOLIC ACID D; SALVIANOLIC ACID E; SALVIANOLIC ACID F; SALVIANOLIC ACID G; SALVIANOLIC ACID J; TANSHINOL; UNCLASSIFIED DRUG; DAN-SHEN ROOT EXTRACT; HERBACEOUS AGENT;

ADULT; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; BEAGLE; CONFERENCE PAPER; CONTROLLED STUDY; DRUG DISPOSITION; DRUG ELIMINATION; DRUG EXCRETION; DRUG HALF LIFE; DRUG ISOLATION; DRUG METABOLISM; DRUG STABILITY; HUMAN; HUMAN EXPERIMENT; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; NORMAL HUMAN; PLANT ROOT; PRIORITY JOURNAL; RAT; SALVIA MILTIORRHIZA; ANIMAL; CHEMISTRY; DOG; INTRAVENOUS DRUG ADMINISTRATION; METABOLISM;

CANIS FAMILIARIS; RATTUS; SALVIA MILTIORRHIZA;

ANIMALS; CATECHOLS; DOGS; DRUGS, CHINESE HERBAL; HUMANS; INJECTIONS, INTRAVENOUS; MALE; RATS; SALVIA MILTIORRHIZA;

EID: 84929075832     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.114.061473     Document Type: Conference Paper

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