-
1
-
-
77954740501
-
Metastatic behavior of breast cancer subtypes
-
PID: 20498394
-
Kennecke H, Yerushalmi R, Woods R, Cheang MC, Voduc D, Speers CH, et al. Metastatic behavior of breast cancer subtypes. J Clin Oncol. 2010;28(20):3271–7.
-
(2010)
J Clin Oncol
, vol.28
, Issue.20
, pp. 3271-3277
-
-
Kennecke, H.1
Yerushalmi, R.2
Woods, R.3
Cheang, M.C.4
Voduc, D.5
Speers, C.H.6
-
2
-
-
79960429096
-
Central nervous system metastases in patients with HER2-positive metastatic breast cancer: incidence, treatment, and survival in patients from registHER
-
COI: 1:CAS:528:DC%2BC3MXovFehtLs%3D, PID: 21768129
-
Brufsky AM, Mayer M, Rugo HS, Kaufman PA, Tan-Chiu E, Tripathy D, et al. Central nervous system metastases in patients with HER2-positive metastatic breast cancer: incidence, treatment, and survival in patients from registHER. Clin Cancer Res. 2011;17(14):4834–43.
-
(2011)
Clin Cancer Res
, vol.17
, Issue.14
, pp. 4834-4843
-
-
Brufsky, A.M.1
Mayer, M.2
Rugo, H.S.3
Kaufman, P.A.4
Tan-Chiu, E.5
Tripathy, D.6
-
3
-
-
0026059293
-
Association of c-erbB-2 protein over-expression with high rate of cell proliferation, increased risk of visceral metastasis and poor long-term survival in breast cancer
-
COI: 1:STN:280:DyaK38%2FktVelsQ%3D%3D, PID: 1682277
-
Kallioniemi OP, Holli K, Visakorpi T, Koivula T, Helin HH, Isola JJ. Association of c-erbB-2 protein over-expression with high rate of cell proliferation, increased risk of visceral metastasis and poor long-term survival in breast cancer. Int J Cancer. 1991;49(5):650–5.
-
(1991)
Int J Cancer
, vol.49
, Issue.5
, pp. 650-655
-
-
Kallioniemi, O.P.1
Holli, K.2
Visakorpi, T.3
Koivula, T.4
Helin, H.H.5
Isola, J.J.6
-
4
-
-
41549138328
-
The role of efflux and uptake transporters in [N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine (GW572016, lapatinib) disposition and drug interactions
-
COI: 1:CAS:528:DC%2BD1cXktVeltb0%3D, PID: 18216274
-
Polli JW, Humphreys JE, Harmon KA, Castellino S, O’Mara MJ, Olson KL, et al. The role of efflux and uptake transporters in [N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine (GW572016, lapatinib) disposition and drug interactions. Drug Metab Dispos. 2008;36(4):695–701.
-
(2008)
Drug Metab Dispos
, vol.36
, Issue.4
, pp. 695-701
-
-
Polli, J.W.1
Humphreys, J.E.2
Harmon, K.A.3
Castellino, S.4
O’Mara, M.J.5
Olson, K.L.6
-
5
-
-
34547846251
-
Consensus nomenclature for in vivo imaging of reversibly binding radioligands
-
COI: 1:CAS:528:DC%2BD2sXptlSqtrc%3D, PID: 17519979
-
Innis RB, Cunningham VJ, Delforge J, Fujita M, Gjedde A, Gunn RN, et al. Consensus nomenclature for in vivo imaging of reversibly binding radioligands. J Cereb Blood Flow Metab. 2007;27(9):1533–9.
-
(2007)
J Cereb Blood Flow Metab
, vol.27
, Issue.9
, pp. 1533-1539
-
-
Innis, R.B.1
Cunningham, V.J.2
Delforge, J.3
Fujita, M.4
Gjedde, A.5
Gunn, R.N.6
-
6
-
-
23944476155
-
Phase I safety, pharmacokinetics, and clinical activity study of lapatinib (GW572016), a reversible dual inhibitor of epidermal growth factor receptor tyrosine kinases, in heavily pretreated patients with metastatic carcinomas
-
COI: 1:CAS:528:DC%2BD2MXpslOrtL0%3D, PID: 15955900
-
Burris 3rd HA, Hurwitz HI, Dees EC, Dowlati A, Blackwell KL, O’Neil B, et al. Phase I safety, pharmacokinetics, and clinical activity study of lapatinib (GW572016), a reversible dual inhibitor of epidermal growth factor receptor tyrosine kinases, in heavily pretreated patients with metastatic carcinomas. J Clin Oncol. 2005;23(23):5305–13.
-
(2005)
J Clin Oncol
, vol.23
, Issue.23
, pp. 5305-5313
-
-
Burris, H.A.1
Hurwitz, H.I.2
Dees, E.C.3
Dowlati, A.4
Blackwell, K.L.5
O’Neil, B.6
-
7
-
-
33645131649
-
Noninvasive quantification of cerebral blood volume in humans during functional activation
-
PID: 16278086
-
Gu H, Lu H, Ye FQ, Stein EA, Yang Y. Noninvasive quantification of cerebral blood volume in humans during functional activation. Neuroimage. 2006;30(2):377–87.
-
(2006)
Neuroimage
, vol.30
, Issue.2
, pp. 377-387
-
-
Gu, H.1
Lu, H.2
Ye, F.Q.3
Stein, E.A.4
Yang, Y.5
-
8
-
-
84860003304
-
Lapatinib distribution in HER2 overexpressing experimental brain metastases of breast cancer
-
COI: 1:CAS:528:DC%2BC3MXhtleqsLbN, PID: 22011930
-
Taskar KS, Rudaraju V, Mittapalli RK, Samala R, Thorsheim HR, Lockman J, et al. Lapatinib distribution in HER2 overexpressing experimental brain metastases of breast cancer. Pharm Res. 2012;29(3):770–81.
-
(2012)
Pharm Res
, vol.29
, Issue.3
, pp. 770-781
-
-
Taskar, K.S.1
Rudaraju, V.2
Mittapalli, R.K.3
Samala, R.4
Thorsheim, H.R.5
Lockman, J.6
-
9
-
-
84913590602
-
Cancer: evolution within a lifetime
-
COI: 1:CAS:528:DC%2BC2cXitFCkurnM, PID: 25292359
-
Gerlinger M, McGranahan N, Dewhurst SM, Burrell RA, Tomlinson I, Swanton C. Cancer: evolution within a lifetime. Annu Rev Genet. 2014;48:215–36.
-
(2014)
Annu Rev Genet.
, vol.48
, pp. 215-236
-
-
Gerlinger, M.1
McGranahan, N.2
Dewhurst, S.M.3
Burrell, R.A.4
Tomlinson, I.5
Swanton, C.6
-
10
-
-
84922142034
-
Capecitabine and lapatinib uptake in surgically resected brain metastases from metastatic breast cancer patients: a prospective study
-
PID: 25015089
-
Morikawa A, Peereboom DM, Thorsheim HR, Samala R, Balyan R, Murphy CG, et al. Capecitabine and lapatinib uptake in surgically resected brain metastases from metastatic breast cancer patients: a prospective study. Neuro Oncol. 2015;17(2):289–95.
-
(2015)
Neuro Oncol
, vol.17
, Issue.2
, pp. 289-295
-
-
Morikawa, A.1
Peereboom, D.M.2
Thorsheim, H.R.3
Samala, R.4
Balyan, R.5
Murphy, C.G.6
-
11
-
-
63149110733
-
Multicenter phase II study of lapatinib in patients with brain metastases from HER2-positive breast cancer
-
COI: 1:CAS:528:DC%2BD1MXitVOktLo%3D, PID: 19228746
-
Lin NU, Dieras V, Paul D, Lossignol D, Christodoulou C, Stemmler HJ, et al. Multicenter phase II study of lapatinib in patients with brain metastases from HER2-positive breast cancer. Clin Cancer Res. 2009;15(4):1452–9.
-
(2009)
Clin Cancer Res
, vol.15
, Issue.4
, pp. 1452-1459
-
-
Lin, N.U.1
Dieras, V.2
Paul, D.3
Lossignol, D.4
Christodoulou, C.5
Stemmler, H.J.6
-
12
-
-
84871722407
-
Lapatinib plus capecitabine in patients with previously untreated brain metastases from HER2-positive metastatic breast cancer (LANDSCAPE): a single-group phase 2 study
-
COI: 1:CAS:528:DC%2BC3sXhsV2msQ%3D%3D, PID: 23122784
-
Bachelot T, Romieu G, Campone M, Dieras V, Cropet C, Dalenc F, et al. Lapatinib plus capecitabine in patients with previously untreated brain metastases from HER2-positive metastatic breast cancer (LANDSCAPE): a single-group phase 2 study. Lancet Oncol. 2013;14(1):64–71.
-
(2013)
Lancet Oncol
, vol.14
, Issue.1
, pp. 64-71
-
-
Bachelot, T.1
Romieu, G.2
Campone, M.3
Dieras, V.4
Cropet, C.5
Dalenc, F.6
-
13
-
-
59449088659
-
Evaluation of lapatinib and topotecan combination therapy: tissue culture, murine xenograft, and phase I clinical trial data
-
COI: 1:CAS:528:DC%2BD1cXhsVegt77E, PID: 19047120
-
Molina JR, Kaufmann SH, Reid JM, Rubin SD, Galvez-Peralta M, Friedman R, et al. Evaluation of lapatinib and topotecan combination therapy: tissue culture, murine xenograft, and phase I clinical trial data. Clin Cancer Res. 2008;14(23):7900–8.
-
(2008)
Clin Cancer Res
, vol.14
, Issue.23
, pp. 7900-7908
-
-
Molina, J.R.1
Kaufmann, S.H.2
Reid, J.M.3
Rubin, S.D.4
Galvez-Peralta, M.5
Friedman, R.6
-
14
-
-
59649115878
-
An unexpected synergist role of P-glycoprotein and breast cancer resistance protein on the central nervous system penetration of the tyrosine kinase inhibitor lapatinib (N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine; GW572016)
-
COI: 1:CAS:528:DC%2BD1MXhs1Krtro%3D, PID: 19056914
-
Polli JW, Olson KL, Chism JP, John-Williams LS, Yeager RL, Woodard SM, et al. An unexpected synergist role of P-glycoprotein and breast cancer resistance protein on the central nervous system penetration of the tyrosine kinase inhibitor lapatinib (N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine; GW572016). Drug Metab Dispos. 2009;37(2):439–42.
-
(2009)
Drug Metab Dispos
, vol.37
, Issue.2
, pp. 439-442
-
-
Polli, J.W.1
Olson, K.L.2
Chism, J.P.3
John-Williams, L.S.4
Yeager, R.L.5
Woodard, S.M.6
-
15
-
-
9144228178
-
Expression of the c-ErbB-2/HER2 proto-oncogene in normal hematopoietic cells
-
COI: 1:CAS:528:DC%2BD3sXotlGktbg%3D, PID: 12960261
-
Leone F, Perissinotto E, Cavalloni G, Fonsato V, Bruno S, Surrenti N, et al. Expression of the c-ErbB-2/HER2 proto-oncogene in normal hematopoietic cells. J Leukoc Biol. 2003;74(4):593–601.
-
(2003)
J Leukoc Biol
, vol.74
, Issue.4
, pp. 593-601
-
-
Leone, F.1
Perissinotto, E.2
Cavalloni, G.3
Fonsato, V.4
Bruno, S.5
Surrenti, N.6
-
16
-
-
84933556321
-
-
Pivot X, Manikhas A, Zurawski B, Chmielowska E, Karaszewska B, Allerton R, et al. CEREBEL (EGF111438): a phase III, randomized, open-label study of lapatinib plus capecitabine versus trastuzumab plus capecitabine in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer. J Clin Oncol. 2015. Epub: 2015/01/22
-
Pivot X, Manikhas A, Zurawski B, Chmielowska E, Karaszewska B, Allerton R, et al. CEREBEL (EGF111438): a phase III, randomized, open-label study of lapatinib plus capecitabine versus trastuzumab plus capecitabine in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer. J Clin Oncol. 2015. Epub: 2015/01/22.
-
-
-
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