-
1
-
-
84908573757
-
FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer (FIRE-3): A randomised, open-label, phase 3 trial
-
V. Heinemann, L.F. von Weikersthal, T. Decker, A. Kiani, U. Vehling-Kaiser, and S.E. Al-Batran FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer (FIRE-3): a randomised, open-label, phase 3 trial Lancet Oncol 15 10 2014 1065 1075
-
(2014)
Lancet Oncol
, vol.15
, Issue.10
, pp. 1065-1075
-
-
Heinemann, V.1
Von Weikersthal, L.F.2
Decker, T.3
Kiani, A.4
Vehling-Kaiser, U.5
Al-Batran, S.E.6
-
2
-
-
84908139591
-
Initial therapy with FOLFOXIRI and bevacizumab for metastatic colorectal cancer
-
F. Loupakis, C. Cremolini, G. Masi, S. Lonardi, V. Zagonel, and L. Salvatore Initial therapy with FOLFOXIRI and bevacizumab for metastatic colorectal cancer N Engl J Med 371 17 2014 1609 1618
-
(2014)
N Engl J Med
, vol.371
, Issue.17
, pp. 1609-1618
-
-
Loupakis, F.1
Cremolini, C.2
Masi, G.3
Lonardi, S.4
Zagonel, V.5
Salvatore, L.6
-
3
-
-
42949149159
-
Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: A randomized phase III study
-
L.B. Saltz, S. Clarke, E. Diaz-Rubio, W. Scheithauer, A. Figer, and R. Wong Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: a randomized phase III study J Clin Oncol 26 12 2008 2013 2019
-
(2008)
J Clin Oncol
, vol.26
, Issue.12
, pp. 2013-2019
-
-
Saltz, L.B.1
Clarke, S.2
Diaz-Rubio, E.3
Scheithauer, W.4
Figer, A.5
Wong, R.6
-
4
-
-
37049022436
-
FOLFOX in patients aged between 76 and 80 years with metastatic colorectal cancer: An exploratory cohort of the OPTIMOX1 study
-
A. Figer, N. Perez-Staub, E. Carola, C. Tournigand, G. Lledo, and M. Flesch FOLFOX in patients aged between 76 and 80 years with metastatic colorectal cancer: an exploratory cohort of the OPTIMOX1 study Cancer 110 12 2007 2666 2671
-
(2007)
Cancer
, vol.110
, Issue.12
, pp. 2666-2671
-
-
Figer, A.1
Perez-Staub, N.2
Carola, E.3
Tournigand, C.4
Lledo, G.5
Flesch, M.6
-
5
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
H. Hurwitz, L. Fehrenbacher, W. Novotny, T. Cartwright, J. Hainsworth, and W. Heim Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer N Engl J Med 350 23 2004 2335 2342
-
(2004)
N Engl J Med
, vol.350
, Issue.23
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
Cartwright, T.4
Hainsworth, J.5
Heim, W.6
-
6
-
-
67649201009
-
Comparing safety and efficacy of first-line irinotecan/fluoropyrimidine combinations in elderly versus nonelderly patients with metastatic colorectal cancer: Findings from the bolus, infusional, or capecitabine with camptostar-celecoxib study
-
N.A. Jackson, J. Barrueco, R. Soufi-Mahjoubi, J. Marshall, E. Mitchell, and X. Zhang Comparing safety and efficacy of first-line irinotecan/fluoropyrimidine combinations in elderly versus nonelderly patients with metastatic colorectal cancer: findings from the bolus, infusional, or capecitabine with camptostar-celecoxib study Cancer 115 12 2009 2617 2629
-
(2009)
Cancer
, vol.115
, Issue.12
, pp. 2617-2629
-
-
Jackson, N.A.1
Barrueco, J.2
Soufi-Mahjoubi, R.3
Marshall, J.4
Mitchell, E.5
Zhang, X.6
-
7
-
-
20544471876
-
Combined analysis of efficacy: The addition of bevacizumab to fluorouracil/leucovorin improves survival for patients with metastatic colorectal cancer
-
F.F. Kabbinavar, J. Hambleton, R.D. Mass, H.I. Hurwitz, E. Bergsland, and S. Sarkar Combined analysis of efficacy: the addition of bevacizumab to fluorouracil/leucovorin improves survival for patients with metastatic colorectal cancer J Clin Oncol 23 16 2005 3706 3712
-
(2005)
J Clin Oncol
, vol.23
, Issue.16
, pp. 3706-3712
-
-
Kabbinavar, F.F.1
Hambleton, J.2
Mass, R.D.3
Hurwitz, H.I.4
Bergsland, E.5
Sarkar, S.6
-
8
-
-
33644843853
-
OPTIMOX1: A randomized study of FOLFOX4 or FOLFOX7 with oxaliplatin in a stop-and-Go fashion in advanced colorectal cancer-A GERCOR study
-
C. Tournigand, A. Cervantes, A. Figer, G. Lledo, M. Flesch, and M. Buyse OPTIMOX1: a randomized study of FOLFOX4 or FOLFOX7 with oxaliplatin in a stop-and-Go fashion in advanced colorectal cancer-a GERCOR study J Clin Oncol 24 3 2006 394 400
-
(2006)
J Clin Oncol
, vol.24
, Issue.3
, pp. 394-400
-
-
Tournigand, C.1
Cervantes, A.2
Figer, A.3
Lledo, G.4
Flesch, M.5
Buyse, M.6
-
9
-
-
0037208589
-
Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer
-
F. Kabbinavar, H.I. Hurwitz, L. Fehrenbacher, N.J. Meropol, W.F. Novotny, and G. Lieberman Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer J Clin Oncol 21 1 2003 60 65
-
(2003)
J Clin Oncol
, vol.21
, Issue.1
, pp. 60-65
-
-
Kabbinavar, F.1
Hurwitz, H.I.2
Fehrenbacher, L.3
Meropol, N.J.4
Novotny, W.F.5
Lieberman, G.6
-
10
-
-
20544478429
-
Addition of bevacizumab to bolus fluorouracil and leucovorin in first-line metastatic colorectal cancer: Results of a randomized phase II trial
-
F.F. Kabbinavar, J. Schulz, M. McCleod, T. Patel, J.T. Hamm, and J.R. Hecht Addition of bevacizumab to bolus fluorouracil and leucovorin in first-line metastatic colorectal cancer: results of a randomized phase II trial J Clin Oncol 23 16 2005 3697 3705
-
(2005)
J Clin Oncol
, vol.23
, Issue.16
, pp. 3697-3705
-
-
Kabbinavar, F.F.1
Schulz, J.2
McCleod, M.3
Patel, T.4
Hamm, J.T.5
Hecht, J.R.6
-
11
-
-
84884700039
-
Bevacizumab plus capecitabine versus capecitabine alone in elderly patients with previously untreated metastatic colorectal cancer (AVEX): An open-label, randomised phase 3 trial
-
D. Cunningham, I. Lang, E. Marcuello, V. Lorusso, J. Ocvirk, and D.B. Shin Bevacizumab plus capecitabine versus capecitabine alone in elderly patients with previously untreated metastatic colorectal cancer (AVEX): an open-label, randomised phase 3 trial Lancet Oncol 14 11 2013 1077 1085
-
(2013)
Lancet Oncol
, vol.14
, Issue.11
, pp. 1077-1085
-
-
Cunningham, D.1
Lang, I.2
Marcuello, E.3
Lorusso, V.4
Ocvirk, J.5
Shin, D.B.6
-
12
-
-
0029835349
-
Development of a novel form of an oral 5-fluorouracil derivative (S-1) directed to the potentiation of the tumor selective cytotoxicity of 5-fluorouracil by two biochemical modulators
-
T. Shirasaka, Y. Shimamato, H. Ohshimo, M. Yamaguchi, T. Kato, and K. Yonekura Development of a novel form of an oral 5-fluorouracil derivative (S-1) directed to the potentiation of the tumor selective cytotoxicity of 5-fluorouracil by two biochemical modulators Anticancer Drugs 7 5 1996 548 557
-
(1996)
Anticancer Drugs
, vol.7
, Issue.5
, pp. 548-557
-
-
Shirasaka, T.1
Shimamato, Y.2
Ohshimo, H.3
Yamaguchi, M.4
Kato, T.5
Yonekura, K.6
-
13
-
-
2442674385
-
Phase II study of oral S-1 for treatment of metastatic colorectal carcinoma
-
K. Shirao, A. Ohtsu, H. Takada, Y. Mitachi, K. Hirakawa, and N. Horikoshi Phase II study of oral S-1 for treatment of metastatic colorectal carcinoma Cancer 100 11 2004 2355 2361
-
(2004)
Cancer
, vol.100
, Issue.11
, pp. 2355-2361
-
-
Shirao, K.1
Ohtsu, A.2
Takada, H.3
Mitachi, Y.4
Hirakawa, K.5
Horikoshi, N.6
-
14
-
-
0034089123
-
Phase II study of S-1, a novel oral fluorophyrimidine derivative, in patients with metastatic colorectal carcinoma. S-1 Cooperative Colorectal Carcinoma Study Group
-
A. Ohtsu, H. Baba, Y. Sakata, Y. Mitachi, N. Horikoshi, and K. Sugimachi Phase II study of S-1, a novel oral fluorophyrimidine derivative, in patients with metastatic colorectal carcinoma. S-1 Cooperative Colorectal Carcinoma Study Group Br J Cancer 83 2 2000 141 145
-
(2000)
Br J Cancer
, vol.83
, Issue.2
, pp. 141-145
-
-
Ohtsu, A.1
Baba, H.2
Sakata, Y.3
Mitachi, Y.4
Horikoshi, N.5
Sugimachi, K.6
-
15
-
-
84888130928
-
Leucovorin, fluorouracil, and oxaliplatin plus bevacizumab versus S-1 and oxaliplatin plus bevacizumab in patients with metastatic colorectal cancer (SOFT): An open-label, non-inferiority, randomised phase 3 trial
-
Y. Yamada, D. Takahari, H. Matsumoto, H. Baba, M. Nakamura, and K. Yoshida Leucovorin, fluorouracil, and oxaliplatin plus bevacizumab versus S-1 and oxaliplatin plus bevacizumab in patients with metastatic colorectal cancer (SOFT): an open-label, non-inferiority, randomised phase 3 trial Lancet Oncol 14 13 2013 1278 1286
-
(2013)
Lancet Oncol
, vol.14
, Issue.13
, pp. 1278-1286
-
-
Yamada, Y.1
Takahari, D.2
Matsumoto, H.3
Baba, H.4
Nakamura, M.5
Yoshida, K.6
-
16
-
-
15944398713
-
Japanese translation of common terminology criteria for adverse events (CTCAE), and instructions and guidelines
-
[Japanese translation of common terminology criteria for adverse events (CTCAE), and instructions and guidelines]. Int J Clin Oncol 2004;9(Suppl. 3):1-82.
-
(2004)
Int J Clin Oncol
, vol.9
, pp. 1-82
-
-
-
17
-
-
0034594628
-
New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada
-
P. Therasse, S.G. Arbuck, E.A. Eisenhauer, J. Wanders, R.S. Kaplan, and L. Rubinstein New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada J Natl Cancer Inst 92 3 2000 205 216
-
(2000)
J Natl Cancer Inst
, vol.92
, Issue.3
, pp. 205-216
-
-
Therasse, P.1
Arbuck, S.G.2
Eisenhauer, E.A.3
Wanders, J.4
Kaplan, R.S.5
Rubinstein, L.6
-
18
-
-
0036302615
-
Clinical determinants of survival in patients with 5-fluorouracil-based treatment for metastatic colorectal cancer: Results of a multivariate analysis of 3825 patients
-
C.H. Kohne, D. Cunningham, F. Di Costanzo, B. Glimelius, G. Blijham, and E. Aranda Clinical determinants of survival in patients with 5-fluorouracil-based treatment for metastatic colorectal cancer: results of a multivariate analysis of 3825 patients Ann Oncol 13 2 2002 308 317
-
(2002)
Ann Oncol
, vol.13
, Issue.2
, pp. 308-317
-
-
Kohne, C.H.1
Cunningham, D.2
Di Costanzo, F.3
Glimelius, B.4
Blijham, G.5
Aranda, E.6
-
19
-
-
84868208475
-
S-1 plus oxaliplatin versus capecitabine plus oxaliplatin for first-line treatment of patients with metastatic colorectal cancer: A randomised, non-inferiority phase 3 trial
-
Y.S. Hong, Y.S. Park, H.Y. Lim, J. Lee, T.W. Kim, and K.P. Kim S-1 plus oxaliplatin versus capecitabine plus oxaliplatin for first-line treatment of patients with metastatic colorectal cancer: a randomised, non-inferiority phase 3 trial Lancet Oncol 13 11 2012 1125 1132
-
(2012)
Lancet Oncol
, vol.13
, Issue.11
, pp. 1125-1132
-
-
Hong, Y.S.1
Park, Y.S.2
Lim, H.Y.3
Lee, J.4
Kim, T.W.5
Kim, K.P.6
-
20
-
-
77956150646
-
Irinotecan plus S-1 (IRIS) versus fluorouracil and folinic acid plus irinotecan (FOLFIRI) as second-line chemotherapy for metastatic colorectal cancer: A randomised phase 2/3 non-inferiority study (FIRIS study)
-
K. Muro, N. Boku, Y. Shimada, A. Tsuji, S. Sameshima, and H. Baba Irinotecan plus S-1 (IRIS) versus fluorouracil and folinic acid plus irinotecan (FOLFIRI) as second-line chemotherapy for metastatic colorectal cancer: a randomised phase 2/3 non-inferiority study (FIRIS study) Lancet Oncol 11 9 2010 853 860
-
(2010)
Lancet Oncol
, vol.11
, Issue.9
, pp. 853-860
-
-
Muro, K.1
Boku, N.2
Shimada, Y.3
Tsuji, A.4
Sameshima, S.5
Baba, H.6
-
21
-
-
34447255724
-
Different strategies of sequential and combination chemotherapy for patients with poor prognosis advanced colorectal cancer (MRC FOCUS): A randomised controlled trial
-
M.T. Seymour, T.S. Maughan, J.A. Ledermann, C. Topham, R. James, and S.J. Gwyther Different strategies of sequential and combination chemotherapy for patients with poor prognosis advanced colorectal cancer (MRC FOCUS): a randomised controlled trial Lancet 370 9582 2007 143 152
-
(2007)
Lancet
, vol.370
, Issue.9582
, pp. 143-152
-
-
Seymour, M.T.1
Maughan, T.S.2
Ledermann, J.A.3
Topham, C.4
James, R.5
Gwyther, S.J.6
-
22
-
-
34447277453
-
Sequential versus combination chemotherapy with capecitabine, irinotecan, and oxaliplatin in advanced colorectal cancer (CAIRO): A phase III randomised controlled trial
-
M. Koopman, N.F. Antonini, J. Douma, J. Wals, A.H. Honkoop, and F.L. Erdkamp Sequential versus combination chemotherapy with capecitabine, irinotecan, and oxaliplatin in advanced colorectal cancer (CAIRO): a phase III randomised controlled trial Lancet 370 9582 2007 135 142
-
(2007)
Lancet
, vol.370
, Issue.9582
, pp. 135-142
-
-
Koopman, M.1
Antonini, N.F.2
Douma, J.3
Wals, J.4
Honkoop, A.H.5
Erdkamp, F.L.6
-
23
-
-
80053384385
-
Sequential versus combination chemotherapy for the treatment of advanced colorectal cancer (FFCD 2000-05): An open-label, randomised, phase 3 trial
-
M. Ducreux, D. Malka, J. Mendiboure, P.L. Etienne, P. Texereau, and D. Auby Sequential versus combination chemotherapy for the treatment of advanced colorectal cancer (FFCD 2000-05): an open-label, randomised, phase 3 trial Lancet Oncol 12 11 2011 1032 1044
-
(2011)
Lancet Oncol
, vol.12
, Issue.11
, pp. 1032-1044
-
-
Ducreux, M.1
Malka, D.2
Mendiboure, J.3
Etienne, P.L.4
Texereau, P.5
Auby, D.6
-
24
-
-
0032104347
-
Comorbidity and age as predictors of risk for early mortality of male and female colon carcinoma patients: A population-based study
-
R. Yancik, M.N. Wesley, L.A. Ries, R.J. Havlik, S. Long, and B.K. Edwards Comorbidity and age as predictors of risk for early mortality of male and female colon carcinoma patients: a population-based study Cancer 82 11 1998 2123 2134
-
(1998)
Cancer
, vol.82
, Issue.11
, pp. 2123-2134
-
-
Yancik, R.1
Wesley, M.N.2
Ries, L.A.3
Havlik, R.J.4
Long, S.5
Edwards, B.K.6
|