99mTc-amoxicillin: A novel radiopharmaceutical for infection imaging

Arabian Journal of Chemistry

Volumn 12, Issue 8, 2019, Pages 2533-2539

  Shahzadi, Syeda Kiran ^a   Qadir, Muhammad Abdul ^a   Shabnam, Shahzad ^a   Javed, Muhammad ^b  

^a UNIVERSITY OF THE PUNJAB   (Pakistan)

^b Institute of Nuclear Medicine and Oncology   (Pakistan)

Author keywords

99mTc; 99mTc amoxicillin; Infection imaging; Radiopharmaceutical; Scintigraphy; Streptococcus pneumoniae

Indexed keywords

CHLORINE COMPOUNDS; NUCLEAR MEDICINE;

AMOXICILLIN; RADIOPHARMACEUTICAL; SCINTIGRAPHY; STREPTOCOCCUS PNEUMONIAE; ^99MTC;

BIOCHEMISTRY;

EID: 84928974980     PISSN: 18785352     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.arabjc.2015.04.003     Document Type: Review

References (24)

1. 99mTc-labeled antimicrobial peptide ubiquicidin (29–41) accumulates less in Escherichia coli infection than in Streptococcus pneumoniae infection. J. Nucl. Med. 45 (2004), 849–856.
2. Amoxicillin Susceptibility and Resistance Data (retrieved 20.07.13).
3. 99mTc-ciprofloxacin (Infecton). J. Clin. Pathol. 55 (2001), 817–823.
4. Fischman, A.J., Livni, E., Babich, J., Alpert, N.M., Liu, Y.Y., Thom, E., Cleeland, R., Prosser, B.L., Callahan, R.J., Correia, J.A., Pharmacokinetics of 18F-labeled fleroxacin in rabbits with Escherichia coli infections, studied with positron emission tomography. Antimicrob. Agents Chemother. 36 (1992), 2286–2292.
5. 99mTc-ceftizoxime scintigraphy in normal rats and abscess induced rats. Rev. Esp. Med. Nucl. 24 (2005), 312–318.
6. 99mTc-Infecton, a novel agent for detecting site of infection. J. Clin. Pathol. 51 (1996), 215–219.
7. Langer, O., Brunner, M., Zeitlinger, M., Ziegler, S., Müller, U., Dobrozemsky, G., Lackner, E., Joukhadar, C., Mitterhauser, M., Wadsak, W., Minar, E., Dudczak, R., Kletter, K., Müller, M., In vitro and in vivo evaluation of [18F] ciprofloxacin for the imaging of bacterial infections with PET. Eur. J. Nucl. Med. Mol. Imag. 32 (2005), 143–150.
8. 111In-biotin. Spine 33 (2008), E198–E204.
9. 99mTc-antimicrobial peptides: promising candidates for infection imaging. J. Nucl. Med. 47 (2003), 238–245.
10. Lupetti, A., Welling, M.M., Pauwels, E.K., Nibbering, P.H., Radiolabelled antimicrobial peptides for infection detection. Lancet Infect. Dis. 3 (2003), 223–229.
11. Martin-Comin, J., Soroa, V., Rabiller, G., Galli, R., Cuesta, L., Roca, M., Diagnosis of bone infection with 99mTc-ceftizoxime. Rev. Esp. Med. Nucl., 23, 2004, 357.
12. 99mTc-UBI in humans. Nucl. Med. Biol. 31 (2004), 373–379.
13. 99mTc labeled levofloxacin as an infection imaging agent: a novel method for labeling levofloxacin using cysteine·HCl as co-ligand and in vivo study. Turk. J. Chem. 36 (2012), 267–277.
14. Nibbering, P.H., Welling, M., van den Broek, P.J., Pauwels, E.K.J., Radiolabeled antimicrobial peptides for imaging of infection: a review. Nucl. Med. Commun. 19 (1998), 1117–1121.
15. Sarda, L., Saleh-Mghir, A., Peker, C., Meulemans, A., Crémieux, A.C., Le Guludec, D., Evaluation of (99m)Tc-ciprofloxacin scintigraphy in a rabbit model of Streptococcus pneumoniae prosthetic joint infection. J. Nucl. Med. 43 (2002), 239–245.
16. Sarda, L., Crémieux, A.C., Lebellec, Y., Meulemans, A., Lebtahi, R., Hayem, G., Génin, R., Delahaye, N., Huten, D., Le Guludec, D., Inability of 99mTc-ciprofloxacin scintigraphy to discriminate between septic and sterile osteoarticular diseases. J. Nucl. Med. 44 (2003), 920–926.
17. Siaens, R.H., Rennen, H.J., Boerman, O.C., Dierckx, R., Slegers, G., Synthesis and comparison of Tc-99m-enrofloxacin and Tc-99m-ciprofloxacin. J. Nucl. Med. 45 (2004), 2088–2094.
18. 99mTc ethambutol in tubercular lesion imaging. Tuberc. Res. Treat. Hind. Pub. Corp., 2010, 1–9.
19. Singh, A.K., Verma, J., Bhatnagar, A., Ali, A., Tc-99m labeled sparfloxacin: a specific infection imaging agent. J. Nucl. Med. 2 (2003), 103–109.
20. 99mTc Infection imaging with radiolabeled white-cell imaging in the evaluation of bacterial infection. Lancet 347 (1996), 233–235.
21. 99mTc-labeled human neutrophil peptide-1. J. Nucl. Med. 40 (1999), 2073–2080.
22. Welling, M.M., Paulusma-Annema, A., Balter, H.S., Pauwels, E.K., Nibbering, P.H., Technetium-99m labeled antimicrobial peptides discriminate between bacterial infections and sterile inflammations. Eur. J. Nucl. Med. 27 (2000), 292–301.
23. 99mTc-labeled antimicrobial peptides for detection of bacterial and Candida albicans infections. J. Nucl. Med. 42 (2001), 788–794.
24. Zijlstra, S., Gunawan, J., Freytag, C., Burchert, W., Synthesis and evaluation of fluorine-18 labeled compounds for imaging of bacterial infections with PET. Appl. Radiat. Isot. 64 (2006), 802–807.